Page last updated: 2024-08-21

oleanolic acid and Cancer of Prostate

oleanolic acid has been researched along with Cancer of Prostate in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (33.33)29.6817
2010's11 (61.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Akbaş, F; Bulut, Ş; Ghaffari-Moghaddam, M; Köse, A; Şenol, H; Topçu, G1
Liu, LQ; Tian, FJ; Zhu, WB1
Gattass, CR; Martins, CA; Rocha, GDG; Takiya, CM1
Arbab, AS; Deeb, D; Gao, X; Gautam, SC; Liu, Y1
Lin, X; Liu, G; Liu, J; Liu, M; Ma, L; Wu, N; Zhang, Y1
Cao, L; Gao, H; Qu, S; Yang, J; Yao, M; Zhang, L1
Chen, L; Li, X; Song, Y; Xiao, Y; Xing, Y; Zhang, P; Zhu, H1
Chen, X; Gu, W; Lei, H; Tang, C; Wang, W; Wu, J; Wu, Y; Xiao, W; Xu, H; Zhang, J1
Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Jiang, H1
Arbab, AS; Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Janic, B; Jiang, H; Rojanasakul, Y1
Arbab, AS; Deeb, D; Divine, GW; Dulchavsky, SA; Gao, X; Gautam, SC; Jiang, D; Liu, Y1
Ali, MM; Arbab, AS; Deeb, D; Gao, X; Gautam, SC; Iskander, AS; Janic, B; Shankar, A; Varma, NR1
Deeb, D; Gao, X; Gautam, SC; Liu, Y1
Bomshteyn, A; Hao, M; Katdare, M; Kisilis, E; Oktem, O; Rathnam, P; Saxena, BB; Zhu, L1
Fisher, PB; Hyer, ML; Krajewska, M; Lebedeva, IV; Meyer, C; Reed, JC; Shi, R1
Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC1
Brodie, AM; Grigoryev, DN; Ling, YZ; Liu, Y; Long, BJ; Nnane, IP1
Kim, DS; Kim, JY; Koo, HM1

Other Studies

18 other study(ies) available for oleanolic acid and Cancer of Prostate

ArticleYear
Synthesis and Anticancer Activity of Novel Derivatives of α,β-Unsaturated Ketones Based on Oleanolic Acid: in Vitro and in Silico Studies against Prostate Cancer Cells.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Male; Molecular Docking Simulation; Molecular Structure; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Structure-Activity Relationship

2023
Chikusetsu (CHI) triggers mitochondria-regulated apoptosis in human prostate cancer via reactive oxygen species (ROS) production.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Apoptosis; Apoptosis Inducing Factor; Caspases; Cell Line, Tumor; Cell Proliferation; Endodeoxyribonucleases; Humans; Male; Mitochondria; Oleanolic Acid; Prostatic Neoplasms; Reactive Oxygen Species; Saponins; Signal Transduction

2017
Pomolic acid exhibits anticancer potential against a docetaxel‑resistant PC3 prostate cell line.
    Oncology reports, 2019, Volume: 42, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Epithelial-Mesenchymal Transition; Humans; Male; Multidrug Resistance-Associated Proteins; Oleanolic Acid; Prostatic Neoplasms

2019
Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.
    Molecules (Basel, Switzerland), 2012, Dec-11, Volume: 17, Issue:12

    Topics: Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation; Humans; Male; Mice; NF-kappa B; Oleanolic Acid; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; STAT3 Transcription Factor; Telomerase

2012
Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Male; MCF-7 Cells; Membrane Proteins; Mitochondria; Oleanolic Acid; Oxidative Phosphorylation; Prostatic Neoplasms; Protein Isoforms; Proto-Oncogene Proteins c-myc; Pyruvate Kinase; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014
Saikosaponin‑d inhibits proliferation of DU145 human prostate cancer cells by inducing apoptosis and arresting the cell cycle at G0/G1 phase.
    Molecular medicine reports, 2014, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; G1 Phase Cell Cycle Checkpoints; Humans; Male; Membrane Potential, Mitochondrial; Oleanolic Acid; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Saponins; Tumor Suppressor Protein p53; Up-Regulation

2014
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:6

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Cycle; Cell Proliferation; Flow Cytometry; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation.
    Oncotarget, 2016, Sep-13, Volume: 7, Issue:37

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cysteine Endopeptidases; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Prostatic Neoplasms; Proteolysis; Sumoylation; Xenograft Model Antitumor Assays

2016
Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
    The Prostate, 2009, Jun-01, Volume: 69, Issue:8

    Topics: Animals; Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; NF-kappa B; Nuclear Proteins; Oleanolic Acid; Prostatic Neoplasms; Protein Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Transplantation, Heterologous; Triterpenes

2009
Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism.
    Biochemical pharmacology, 2010, Feb-01, Volume: 79, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Growth Inhibitors; Humans; Male; Oleanolic Acid; Prostatic Neoplasms; Reactive Oxygen Species

2010
Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling.
    Carcinogenesis, 2011, Volume: 32, Issue:5

    Topics: Adenocarcinoma; Animals; Animals, Genetically Modified; Apoptosis; Blotting, Western; Cell Proliferation; Disease Progression; Female; Humans; Immunoenzyme Techniques; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oleanolic Acid; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2011
MRI to assess chemoprevention in transgenic adenocarcinoma of mouse prostate (TRAMP).
    BMC medical imaging, 2011, Dec-13, Volume: 11

    Topics: Animals; Chemoprevention; Disease Progression; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Oleanolic Acid; Prostate; Prostatic Neoplasms; Seminal Vesicles

2011
Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells.
    Biochemical and biophysical research communications, 2012, Jan-06, Volume: 417, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Male; NF-kappa B; Oleanolic Acid; Prostatic Neoplasms; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; TOR Serine-Threonine Kinases

2012
Boc-lysinated-betulonic acid: a potent, anti-prostate cancer agent.
    Bioorganic & medicinal chemistry, 2006, Sep-15, Volume: 14, Issue:18

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Hydrophobic and Hydrophilic Interactions; Immunohistochemistry; In Vitro Techniques; Lysine; Male; Mice; Mice, Nude; Mitosis; Molecular Conformation; Oleanolic Acid; Prostatic Neoplasms; Solubility; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2006
Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Cancer research, 2008, Apr-15, Volume: 68, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; Male; Oleanolic Acid; Prostatic Neoplasms; RNA Interference; RNA, Double-Stranded; RNA, Neoplasm; RNA, Small Interfering

2008
CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Journal of experimental therapeutics & oncology, 2008, Volume: 7, Issue:1

    Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Humans; Male; Mice; NF-kappa B; Nitric Oxide; Oleanolic Acid; Prostatic Neoplasms; Protein Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2008
Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.
    Cancer research, 2000, Dec-01, Volume: 60, Issue:23

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgen Receptor Antagonists; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Cell Division; Chlorocebus aethiops; Finasteride; Growth Inhibitors; Humans; Ketoconazole; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms, Hormone-Dependent; Oleanolic Acid; Pregnadienes; Prostatic Neoplasms; Receptors, Androgen; Saponins; Steroid 17-alpha-Hydroxylase; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2000
Development of C-20 modified betulinic acid derivatives as antitumor agents.
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Adenocarcinoma; Antineoplastic Agents; Betulinic Acid; Drug Screening Assays, Antitumor; Humans; Male; Melanoma; Oleanolic Acid; Pentacyclic Triterpenes; Prostatic Neoplasms; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2001