Page last updated: 2024-08-21

oleanolic acid and Cancer of Ovary

oleanolic acid has been researched along with Cancer of Ovary in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (33.33)29.6817
2010's11 (52.38)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Johnson, RK; Kingston, DG; Prakash Chaturvedula, VS; Schilling, JK1
Bian, M; Fan, R; Liu, W; Liu, Y; Liu, Z; Sun, Y; Xu, Z1
Chen, L; Chen, YC; Li, B; Rankin, GO; Ren, N; Rojanasakul, Y; Tu, Y; Wang, Y; Wu, Y1
Bremner, DH; Chen, X; Li, S; Niu, S; Zhang, H; Zhang, X; Zhang, Y; Zhu, LM1
Chou, YT; Hsieh, SL; Lee, OK; Sung, PL; Wang, PH; Wen, KC; Wu, CW1
Chang, CM; Chen, YJ; Horng, HC; Lee, WL; Sung, PL; Wang, PH; Wen, KC1
Bucur, H; Chen, YC; Chen, ZD; Compton, C; Jia, LY; Li, B; Rankin, GO; Sawant, DA; Tu, YY; Xia, HL1
Gao, FH; Lei, H; Ma, CM; Qin, DJ; Tang, CX; Wang, YY; Wei, W; Wu, YL; Xu, HZ; Yang, L1
Chen, Y; Feng, X; Guan, F; Shan, Y; Wang, M; Wang, Q; Zhao, X1
Cho, YJ; Choi, JH; Jang, DS; Lee, JS; Lee, KT; Woo, JH1
Cai, H; Gao, F; Jin, J; Lei, H; Luo, H; Ma, C; Qin, D; Tang, C; Wang, T; Wang, W; Wang, Y; Wu, Y; Wu, YL; Xiao, W; Xu, H; Zhang, J1
Chen, P; Chen, X; Lin, LG; Lu, JJ; Meng, FC; Qiang, WA; Tang, ZH; Wang, YT; Wu, QS; Zhang, QW1
Ames, RY; Duan, Z; Hornicek, FJ; Mankin, H; Ryan, M; Seiden, MV1
Benedetti-Panici, P; Biffoni, M; Cognetti, F; Ferretti, G; Greggi, S; Mariani, G; Pasquini, L; Petronelli, A; Petrucci, E; Russo, MA; Saulle, E; Scambia, G; Sporn, M; Testa, U1
Brodie, PJ; Callmander, M; Cao, S; Kingston, DG; Rakotobe, E; Randrianaivo, R; Rasamison, VE1
Arbab, AS; Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Guo, AM; Liu, Y1
Arbab, AS; Deeb, D; Gao, X; Gautam, SC; Liu, A; Liu, P; Liu, Y1
Andriantsiferana, R; Chaturvedula, VS; Kingston, DG; Miller, JS; Rasamison, VE; Schilling, JK1
Andreeff, M; Freedman, RS; Hu, W; Konopleva, M; Melichar, B; Melicharova, K1
Berger, JM; Bursuker, I; Hoch, J; Kingston, DG; Mamber, SW; Neddermann, KM; Seo, Y1
Abdel-Kader, M; Adams, H; Dalton, JM; Derveld, I; Hoch, J; Kingston, DG; Malone, S; Mamber, SW; Seo, Y; Werkhoven, MC; Wisse, JH1

Other Studies

21 other study(ies) available for oleanolic acid and Cancer of Ovary

ArticleYear
New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
    Journal of natural products, 2003, Volume: 66, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Guyana; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plant Stems; Plants, Medicinal; Rubiaceae; Stereoisomerism; Triterpenes; Tumor Cells, Cultured

2003
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Jun-02, Volume: 26, Issue:31

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Coordination Complexes; Endoplasmic Reticulum Stress; Female; Gold; Humans; Oleanolic Acid; Ovarian Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Thioredoxin-Disulfide Reductase

2020
Standardized Saponin Extract from Baiye No.1 Tea (
    Molecules (Basel, Switzerland), 2020, Jul-31, Volume: 25, Issue:15

    Topics: Apoptosis; Camellia sinensis; Cell Line, Tumor; Cell Survival; Cyclin A2; Cyclin-Dependent Kinase Inhibitor p27; Female; Flowers; Gene Expression Regulation; Humans; Oleanolic Acid; Ovarian Neoplasms; Plant Extracts; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; S Phase Cell Cycle Checkpoints; Saponins; Signal Transduction; Tumor Suppressor Protein p53

2020
Co-delivery of doxorubicin and oleanolic acid by triple-sensitive nanocomposite based on chitosan for effective promoting tumor apoptosis.
    Carbohydrate polymers, 2020, Nov-01, Volume: 247

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Proliferation; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Mice; Nanocomposites; Oleanolic Acid; Ovarian Neoplasms; Tissue Distribution; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
α2,3-sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; beta-Galactoside alpha-2,3-Sialyltransferase; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Drug Synergism; ErbB Receptors; Female; Humans; Immunohistochemistry; Immunoprecipitation; Kaplan-Meier Estimate; Mice; Mice, Inbred C57BL; Microarray Analysis; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Oleanolic Acid; Ovarian Neoplasms; Ovary; Peritoneal Neoplasms; Peritoneum; Prognosis; Protein Kinase Inhibitors; Saponins; Sialyltransferases; Signal Transduction; Survival Rate

2017
The role of α2,3-linked sialylation on clear cell type epithelial ovarian cancer.
    Taiwanese journal of obstetrics & gynecology, 2018, Volume: 57, Issue:2

    Topics: Adenocarcinoma, Clear Cell; Animals; beta-Galactoside alpha-2,3-Sialyltransferase; Cadherins; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cystadenocarcinoma, Serous; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms, Glandular and Epithelial; Oleanolic Acid; Ovarian Neoplasms; Saponins; Sialyltransferases

2018
Anti-Proliferation Effect of Theasaponin E₁ on the ALDH-Positive Ovarian Cancer Stem-Like Cells.
    Molecules (Basel, Switzerland), 2018, Jun-17, Volume: 23, Issue:6

    Topics: Aldehyde Dehydrogenase; Biomarkers; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Structure; Neoplastic Stem Cells; Oleanolic Acid; Ovarian Neoplasms; Saponins; Tea

2018
Hsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Dithiothreitol; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; MAP Kinase Signaling System; Molecular Structure; Molecular Targeted Therapy; Neoplasm Proteins; Oleanolic Acid; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; RNA Interference; RNA, Small Interfering; Structure-Activity Relationship; Transfection; Up-Regulation

2015
Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells.
    Nutrition and cancer, 2016, Volume: 68, Issue:2

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Oleanolic Acid; Ovarian Neoplasms; Reactive Oxygen Species; Saponins; TOR Serine-Threonine Kinases

2016
Eclalbasaponin II induces autophagic and apoptotic cell death in human ovarian cancer cells.
    Journal of pharmacological sciences, 2016, Volume: 132, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Female; Humans; JNK Mitogen-Activated Protein Kinases; Oleanolic Acid; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Saponins; TOR Serine-Threonine Kinases

2016
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells.
    Oncotarget, 2016, Nov-22, Volume: 7, Issue:47

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Molecular Docking Simulation; Oleanolic Acid; Ovarian Neoplasms; Ubiquitin-Specific Peptidase 7; Up-Regulation; Xenograft Model Antitumor Assays

2016
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Dec-01, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase 2; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; G1 Phase Cell Cycle Checkpoints; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Oleanolic Acid; Ovarian Neoplasms; Saponins

2016
CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:4

    Topics: Apoptosis; Blotting, Western; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Interleukin-6; Oleanolic Acid; Ovarian Neoplasms; Phosphorylation; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tumor Cells, Cultured

2009
High sensitivity of ovarian cancer cells to the synthetic triterpenoid CDDO-Imidazolide.
    Cancer letters, 2009, Sep-18, Volume: 282, Issue:2

    Topics: Antibiotics, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Enzyme Activation; Female; Glutathione; Humans; Imidazoles; Mitochondria; Oleanolic Acid; Ovarian Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; STAT3 Transcription Factor; TNF-Related Apoptosis-Inducing Ligand

2009
Saponins and a lignan derivative of Terminalia tropophylla from the Madagascar Dry Forest.
    Phytochemistry, 2010, Volume: 71, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Ecosystem; Female; Humans; Inhibitory Concentration 50; Lignans; Madagascar; Molecular Structure; Oleanolic Acid; Ovarian Neoplasms; Phytotherapy; Plant Extracts; Plant Roots; Saponins; Terminalia; Triterpenes

2010
Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; NF-kappa B; Oleanolic Acid; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2011
ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Hydrogen Peroxide; Oleanolic Acid; Ovarian Neoplasms; Reactive Oxygen Species; Signal Transduction

2013
Two new triterpene esters from the twigs of Brachylaena ramiflora from the Madagascar rainforest.
    Journal of natural products, 2002, Volume: 65, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Drug Screening Assays, Antitumor; Esters; Female; Humans; Inhibitory Concentration 50; Madagascar; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Ovarian Neoplasms; Palmitates; Pentacyclic Triterpenes; Plant Shoots; Plants, Medicinal; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Triterpenes; Tumor Cells, Cultured

2002
Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
    Gynecologic oncology, 2004, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Female; Growth Inhibitors; Humans; Oleanolic Acid; Ovarian Neoplasms; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors

2004
A new triterpene saponin from Pittosporum viridiflorum from the Madagascar rainforest.
    Journal of natural products, 2002, Volume: 65, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Madagascar; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Ovarian Neoplasms; Plants, Medicinal; Saccharomyces cerevisiae; Saponins; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2002
Bioactive saponins from Acacia tenuifolia from the suriname rainforest.
    Journal of natural products, 2002, Volume: 65, Issue:2

    Topics: Acacia; Animals; Antifungal Agents; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Ovarian Neoplasms; Plants, Medicinal; Saponins; Stereoisomerism; Suriname; Triterpenes; Tumor Cells, Cultured; Yeasts

2002