Page last updated: 2024-08-21

oleanolic acid and Cancer of Colon

oleanolic acid has been researched along with Cancer of Colon in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's8 (38.10)29.6817
2010's8 (38.10)24.3611
2020's4 (19.05)2.80

Authors

AuthorsStudies
Huang, R; Lin, Q; Liu, Z; Xia, X; Yang, J; Zeng, J; Zhao, N1
Paduch, R; Piet, M1
Bahr, HI; El-Sherbiny, M; Elbahaie, AM; Elmahdi, HS; Gabr, AM; Ibrahiem, AT; Soliman, N; Youssef, AM; Zaitone, SA1
Huiwen, M; Jie, T; Qiaoyun, L; Shaojun, Z; Xianjun, F; Xirui, X; Xuqun, S; Yunxin, L1
Cheng, H; Fan, H; Li, L; Miao, Y; Shen, W; Sun, D; Tan, J; Xu, C; Yang, Y; Zhang, F; Zhang, H1
Abekura, F; Chang, HW; Cho, SH; Chung, TW; Ha, KT; Ha, SH; Kim, CH; Kim, JS; Kwon, KM; Lee, YC; Park, JY1
Chae, MK; Cho, J; Jeong, IH; Kim, SM; Lee, C; Ryu, EK; Yim, MS1
Choi, SH; Fink, S; Kim, BG; Letterio, JJ; Markowitz, SD; Robinson, J; Sporn, MB; Yan, M1
Leake, I1
Feng, L; Gu, JF; Jia, XB; Li, Y; Liu, BX; Wang, RP; Wu, J; Yuan, JR; Zhao, BJ; Zhou, JY; Zou, X1
Ai, Y; Huang, Z; Kang, F; Lai, Y; Peng, S; Tian, J; Xue, X; Zhang, Y1
Hong, SH; Kim, BM1
Gurfinkel, DM; Rao, AV1
Andreef, M; Chintharlapalli, S; Konopleva, M; Papineni, S; Safe, S; Samudio, I1
Daniel, H; Juan, ME; Planas, JM; Ruiz-Gutierrez, V; Wenzel, U1
Fong, W; He, M; Jiang, Z; Liang, Z; Zhao, Z1
Indranie, C; Jagan, P; Janakiram, NB; Malisetty, SV; Rao, CV; Steele, VE1
Araújo, FR; Castro, MB; Cunha, WR; Furtado, MA; Furtado, RA; Oliveira, WL; Rodrigues, EP; Tavares, DC1
Hara, A; Kawamori, T; Mori, H; Tanaka, T; Yamahara, J1
Delaude, C; Khan, IA; Lacaille-Dubois, MA; Mitaine-Offer, AC; Miyamoto, T1
Guo, WJ; Li, J; Yang, QY1

Other Studies

21 other study(ies) available for oleanolic acid and Cancer of Colon

ArticleYear
Anti-Colon Cancer Activity of Dietary Phytochemical Soyasaponin I and the Induction of Metabolic Shifts in HCT116.
    Molecules (Basel, Switzerland), 2022, Jul-08, Volume: 27, Issue:14

    Topics: Colonic Neoplasms; Humans; Molecular Docking Simulation; Oleanolic Acid; Phytochemicals; Saponins

2022
Ursolic and oleanolic acids in combination therapy inhibit migration of colon cancer cells through down-regulation of the uPA/uPAR-dependent MMPs pathway.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Cadherins; Colonic Neoplasms; Down-Regulation; Humans; Irinotecan; Matrix Metalloproteinase 2; Oleanolic Acid; Ursolic Acid

2022
Chemopreventive effect of α-hederin/carboplatin combination against experimental colon hyperplasia and impact on JNK signaling.
    Toxicology mechanisms and methods, 2021, Volume: 31, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Carboplatin; Colon; Colonic Neoplasms; Hyperplasia; Male; Mice; Oleanolic Acid; Phosphatidylinositol 3-Kinases

2021
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
    Journal of pharmacological sciences, 2021, Volume: 146, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bassia scoparia; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cysteine Endopeptidases; G1 Phase Cell Cycle Checkpoints; Humans; Oleanolic Acid; Phytotherapy; Proto-Oncogene Proteins c-myc; Resting Phase, Cell Cycle; Signal Transduction

2021
α-Hederin inhibits interleukin 6-induced epithelial-to-mesenchymal transition associated with disruption of JAK2/STAT3 signaling in colon cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 101

    Topics: Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Interleukin-6; Janus Kinase 2; Oleanolic Acid; Saponins; Signal Transduction; STAT3 Transcription Factor

2018
Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Animals; Cell Movement; Colonic Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neoplasm Proteins; NF-kappa B; Oleanolic Acid; Saponins

2019
Hybrid PET/MR imaging of tumors using an oleanolic acid-conjugated nanoparticle.
    Biomaterials, 2013, Volume: 34, Issue:33

    Topics: Animals; Cell Proliferation; Colonic Neoplasms; Ferric Compounds; HT29 Cells; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Nanoparticles; Oleanolic Acid; Positron-Emission Tomography

2013
Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Enzyme Induction; Hydroxyprostaglandin Dehydrogenases; Intestinal Mucosa; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II; Oleanolic Acid; Smad4 Protein; STAT Transcription Factors

2014
Colorectal cancer: chemopreventive action of synthetic triterpenoids in CRC.
    Nature reviews. Gastroenterology & hepatology, 2014, Volume: 11, Issue:7

    Topics: Animals; Carcinogenesis; Colonic Neoplasms; Hydroxyprostaglandin Dehydrogenases; Oleanolic Acid

2014
Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway.
    BMC complementary and alternative medicine, 2014, Oct-24, Volume: 14

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Hedera; Humans; Mitochondria; Oleanolic Acid; Plant Extracts; Plant Leaves

2014
Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.
    Journal of medicinal chemistry, 2015, Mar-12, Volume: 58, Issue:5

    Topics: Amino Acids; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Molecular Structure; Nitric Oxide Donors; Oleanolic Acid; Signal Transduction; Structure-Activity Relationship; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:2

    Topics: Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Caspase 2; Caspase 8; Caspase 9; Cell Line, Tumor; Colonic Neoplasms; Cyclosporine; Flow Cytometry; Humans; Inhibitor of Apoptosis Proteins; Mitochondria; Oleanolic Acid; Oligopeptides; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Saponins; Signal Transduction; Survivin

2011
Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity.
    Nutrition and cancer, 2003, Volume: 47, Issue:1

    Topics: Acetylation; Anticarcinogenic Agents; Cell Division; Colonic Neoplasms; Fabaceae; Fermentation; Humans; Molecular Structure; Oleanolic Acid; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured

2003
2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways.
    Molecular pharmacology, 2005, Volume: 68, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Oleanolic Acid; PPAR gamma; Signal Transduction

2005
Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells.
    The British journal of nutrition, 2008, Volume: 100, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Death; Cell Membrane Permeability; Cell Proliferation; Colonic Neoplasms; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; HT29 Cells; Humans; Necrosis; Olea; Oleanolic Acid; Reactive Oxygen Species; Triterpenes

2008
A comparable, chemical and pharmacological analysis of the traditional Chinese medicinal herbs Oldenlandia diffusa and O. corymbosa and a new valuation of their biological potential.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:4

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyclopentane Monoterpenes; Glucosides; Humans; Iridoids; Oldenlandia; Oleanolic Acid; Phytotherapy; Plant Extracts; Pyrans; Zebrafish

2008
Chemoprevention of colon carcinogenesis by oleanolic acid and its analog in male F344 rats and modulation of COX-2 and apoptosis in human colon HT-29 cancer cells.
    Pharmaceutical research, 2008, Volume: 25, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; HT29 Cells; Humans; Macrophages; Male; Mice; Nitric Oxide Synthase Type II; Oleanolic Acid; Precancerous Conditions; Rats; Rats, Inbred F344

2008
Ursolic acid and oleanolic acid suppress preneoplastic lesions induced by 1,2-dimethylhydrazine in rat colon.
    Toxicologic pathology, 2008, Volume: 36, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Colonic Neoplasms; Male; Melastomataceae; Oleanolic Acid; Plant Components, Aerial; Precancerous Conditions; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2008
Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats.
    Cancer research, 1995, Mar-15, Volume: 55, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biogenic Polyamines; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Nucleolus Organizer Region; Oleanolic Acid; Ornithine Decarboxylase; Precancerous Conditions; Rats; Rats, Inbred F344; Sesquiterpenes

1995
Three new triterpene saponins from two species of Carpolobia.
    Journal of natural products, 2002, Volume: 65, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Cisplatin; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Molecular Structure; Nigeria; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Plants, Medicinal; Polygalaceae; Saponins; Stereoisomerism; Triterpenes; Tumor Cells, Cultured

2002
Effects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15.
    World journal of gastroenterology, 2002, Volume: 8, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Humans; Oleanolic Acid; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2002