Page last updated: 2024-08-21

oleanolic acid and Alzheimer Disease

oleanolic acid has been researched along with Alzheimer Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Basile, L; Copani, A; Giuffrida, ML; Guccione, S; Merlo, S; Sortino, MA1
Guo, Q; He, J; Li, H; Yao, L; Zhang, H1
Berté, TE; Bürger, C; Cechinel-Filho, V; Dalmagro, AP; de Souza, MM; Dos Santos, DA; Gonçalves, AE; Meyre-Silva, C; Weber, CJ; Zimath, PL1
Guo, W; Liu, S; Sun, W; Wang, K; Xu, J; Zhang, L; Zhang, Y; Zhou, Z1
Wang, S; Xu, Y; Yang, H; Yu, L; Zhu, X1
Ahn, YJ; Kwon, HW; Na, YE; Perumalsamy, H; Wang, X1
Adcott, J; Bertrand, HC; Callard, R; Castillo-Quan, JI; Cochemé, HM; Gatliff, J; Gomez Perez-Nievas, B; Ivanov, DK; Kerr, F; Khericha, M; Martinez, P; Noble, W; Partridge, L; Snoeren, I; Sofola-Adesakin, O; Thornton, J; Wells, G1
Calingasan, NY; Dumont, M; Flint Beal, M; Gouras, GK; Liby, K; Lin, MT; Nathan, C; Sporn, M; Tampellini, D; Wille, E; Williams, C1
Hu, YZ; Li, P; Xu, L; Yang, ZL; Zhou, YQ1
Chen, XL; Hu, HT; Liu, Y; Qian, YH; Ren, HM; Xu, JH1

Other Studies

10 other study(ies) available for oleanolic acid and Alzheimer Disease

ArticleYear
Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Alzheimer Disease; Cell Cycle; Cell Death; Cell Division; DNA Polymerase beta; DNA Replication; Enzyme Inhibitors; Flavones; Humans; Molecular Structure; Neurons; Neuroprotective Agents; Parkinson Disease

2015
Oleanolic acid alleviates oxidative stress in Alzheimer's disease by regulating stanniocalcin-1 and uncoupling protein-2 signalling.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:7

    Topics: Alzheimer Disease; Cell Line; Glycoproteins; Humans; Oleanolic Acid; Oxidative Stress; Signal Transduction; Uncoupling Protein 2

2020
Taraxerol as a possible therapeutic agent on memory impairments and Alzheimer's disease: Effects against scopolamine and streptozotocin-induced cognitive dysfunctions.
    Steroids, 2018, Volume: 132

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Cognitive Dysfunction; Male; Maze Learning; Memory; Oleanolic Acid; Rats; Rats, Wistar; Scopolamine; Streptozocin

2018
Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer's Disease Model Rats by Maintaining Synaptic Plasticity.
    CNS & neurological disorders drug targets, 2018, Volume: 17, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antipsychotic Agents; Avoidance Learning; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Electric Stimulation; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Microscopy, Electron, Transmission; Oleanolic Acid; Peptide Fragments; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Synaptic Potentials

2018
Esculentoside A suppresses Aβ(1-42)-induced neuroinflammation by down-regulating MAPKs pathways in vivo.
    Neurological research, 2015, Volume: 37, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Astrocytes; Disease Models, Animal; Down-Regulation; Encephalitis; Hippocampus; Inflammation Mediators; Male; MAP Kinase Signaling System; Memory; Mice; Mice, Inbred C57BL; Microglia; Oleanolic Acid; Peptide Fragments; Saponins

2015
Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease.
    Scientific reports, 2015, Nov-04, Volume: 5

    Topics: Agastache; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Animals, Genetically Modified; Behavior, Animal; Disease Models, Animal; Drosophila; Eating; Eye; Flavones; Fluorescence Resonance Energy Transfer; Gene Expression Regulation; Humans; Longevity; Male; Oleanolic Acid; Phenotype; Triterpenes

2015
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease.
    PLoS genetics, 2017, Volume: 13, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Gene Expression Profiling; Glycogen Synthase Kinase 3; Humans; Kelch-Like ECH-Associated Protein 1; Lithium Chloride; Longevity; Mice; Microscopy, Confocal; Neurons; NF-E2-Related Factor 2; Oleanolic Acid; Peptide Fragments; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Thiadiazoles; Triazoles

2017
Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.
    Journal of neurochemistry, 2009, Volume: 109, Issue:2

    Topics: Alzheimer Disease; Animals; Cricetinae; Disease Models, Animal; Female; Memory; Memory Disorders; Mice; Mice, Transgenic; Oleanolic Acid; Plaque, Amyloid; Triterpenes

2009
Akebia saponin D, a saponin component from Dipsacus asper Wall, protects PC 12 cells against amyloid-beta induced cytotoxicity.
    Cell biology international, 2009, Volume: 33, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Cell Survival; Cytoprotection; Dipsacaceae; Drugs, Chinese Herbal; L-Lactate Dehydrogenase; Oleanolic Acid; PC12 Cells; Rats; Saponins

2009
The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by beta-amyloid protein 25-35.
    Anatomical science international, 2002, Volume: 77, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Hydro-Lyases; Lipid Peroxidation; Malondialdehyde; Neurons; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Peptide Fragments; Rats; Saponins; Tetrazolium Salts; Thiazoles

2002