Page last updated: 2024-08-21

oleanolic acid and Acute Promyelocytic Leukemia

oleanolic acid has been researched along with Acute Promyelocytic Leukemia in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, CW; Ding, Y; Kang, HK; Kim, EJ; Kim, YH; Li, W; Sun, YN; Yan, XT; Yang, SY1
Bednarczyk-Cwynar, B; Paszel-Jaworska, A; Rubiś, B; Rybczyńska, M; Zaprutko, L1
Chang, CD; Hsu, JL; Huang, TC; Lin, PY; Rawendra, RD; Shih, WL1
Abdelrahim, M; Andreeff, M; Chen, W; Coombes, KR; Ju, Z; Kantarjian, H; Kardassis, D; Konopleva, M; Kornblau, S; Ling, X; Meyer, C; Qiu, Y; Ruvolo, V; Safe, S; Schimmer, A; Schober, W; Tsao, T; Watt, JC1
Barker, J; Carew, M; Ganbold, M; Jones, L; Ma, R1
Birkey Reffey, S; Gribble, GW; Heiss, EH; Honda, T; Itoh, S; Miyazono, K; Place, AE; Risingsong, R; Roberts, AB; Sporn, MB; Suh, N; ten Dijke, P; Williams, CR1
Ikeda, T; Kimura, F; Kufe, D; Motoyoshi, K; Nakata, Y; Ogura, K; Sato, K; Sporn, M1
Andreeff, M; Contractor, R; Issa, JP; Kogan, SC; Kondo, Y; Konoplev, S; Konopleva, M; Ling, X; Nagaoka, I; Ohsaka, A; Shi, Y; Tabe, Y; Tsao, T; Tsutsumi-Ishii, Y; Watt, JC1
Chen, YJ; Kuroyanagi, M; Takagi, R; Taki, T; Ueno, A; Umehara, K1

Trials

1 trial(s) available for oleanolic acid and Acute Promyelocytic Leukemia

ArticleYear
Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia.
    Cancer research, 2010, Jun-15, Volume: 70, Issue:12

    Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Chromatin Immunoprecipitation; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Luciferases; Mediator Complex Subunit 1; Neoplasm Recurrence, Local; Nitric Oxide; Oleanolic Acid; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering

2010

Other Studies

8 other study(ies) available for oleanolic acid and Acute Promyelocytic Leukemia

ArticleYear
Oleanane-type triterpenoid saponins from the roots of Pulsatilla koreana and their apoptosis-inducing effects on HL-60 human promyelocytic leukemia cells.
    Archives of pharmacal research, 2013, Volume: 36, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Promyelocytic, Acute; Oleanolic Acid; Plant Extracts; Plant Roots; Pulsatilla; Saponins; Spectrum Analysis

2013
Proapoptotic activity and ABCC1-related multidrug resistance reduction ability of semisynthetic oleanolic acid derivatives DIOXOL and HIMOXOL in human acute promyelocytic leukemia cells.
    Chemico-biological interactions, 2015, Dec-05, Volume: 242

    Topics: Antineoplastic Agents; Apoptosis; DNA Fragmentation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; MAP Kinase Signaling System; Molecular Targeted Therapy; Multidrug Resistance-Associated Proteins; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Transcription Factor RelA

2015
Potentiation of Acute Promyelocytic Leukemia Cell Differentiation and Prevention of Leukemia Development in Mice by Oleanolic Acid.
    Anticancer research, 2015, Volume: 35, Issue:12

    Topics: Animals; Cell Differentiation; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Mice; Oleanolic Acid; Tretinoin

2015
Cytotoxicity and bioavailability studies on a decoction of Oldenlandia diffusa and its fractions separated by HPLC.
    Journal of ethnopharmacology, 2010, Sep-15, Volume: 131, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; HL-60 Cells; Humans; Intestinal Mucosa; Leukemia, Promyelocytic, Acute; Oldenlandia; Oleanolic Acid; Phytotherapy; Triterpenes; Ursolic Acid

2010
Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.
    Cancer research, 2003, Mar-15, Volume: 63, Issue:6

    Topics: Acetyltransferases; Animals; Cell Cycle Proteins; DNA-Binding Proteins; Drug Synergism; Histone Acetyltransferases; Imidazoles; Leukemia, Promyelocytic, Acute; Lung; Macrophages; Mice; Mink; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oleanolic Acid; p300-CBP Transcription Factors; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad7 Protein; Terpenes; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triterpenes

2003
Triterpenoid CDDO-Im downregulates PML/RARalpha expression in acute promyelocytic leukemia cells.
    Cell death and differentiation, 2005, Volume: 12, Issue:5

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Caspases; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Leukemic; Humans; Imidazoles; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Nuclear Proteins; Oleanolic Acid; Oxides; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Proteins

2005
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
    Cancer biology & therapy, 2007, Volume: 6, Issue:12

    Topics: Acetylation; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Histones; Humans; Leukemia, Promyelocytic, Acute; Mice; Mice, Transgenic; Nicotinic Acids; Oleanolic Acid; PPAR gamma; Promoter Regions, Genetic; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Response Elements; RNA, Small Interfering; Tetrahydronaphthalenes; Tretinoin

2007
Studies on differentiation-inducing activities of triterpenes.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:2

    Topics: Animals; Cell Differentiation; Cell Division; Granulocytes; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Macrophages; Mice; Oleanolic Acid; Phagocytosis; Plant Extracts; Plants, Medicinal; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

1992