oleanane and Ovarian-Neoplasms

oleanane has been researched along with Ovarian-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for oleanane and Ovarian-Neoplasms

ArticleYear
Saponins and a lignan derivative of Terminalia tropophylla from the Madagascar Dry Forest.
    Phytochemistry, 2010, Volume: 71, Issue:1

    A study of an EtOH extract obtained from the roots of the Madagascan plant Terminalia tropophylla H. Perrier (Combretaceae) led to isolation of the oleanane-type triterpenoid saponin 1, the lignan derivative 2, and the two known saponins arjunglucoside I (3) and sericoside (4). The structures of compounds 1 (terminaliaside A) and 2 (4'-O-cinnamoyl cleomiscosin A) were elucidated using 1D and 2D NMR experiments and mass spectrometry. Compound 1 showed antiproliferative activity against the A2780 human ovarian cancer cell line with an IC(50) value of 1.2 microM.

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Ecosystem; Female; Humans; Inhibitory Concentration 50; Lignans; Madagascar; Molecular Structure; Oleanolic Acid; Ovarian Neoplasms; Phytotherapy; Plant Extracts; Plant Roots; Saponins; Terminalia; Triterpenes

2010