olanzapine and Thrombocytopenia

The use of atypical antipsychotics in the United States has increased over the past decade, since atypical antipsychotics such as olanzapine and clozapine were introduced. Of the adverse effects associated with olanzapine, bone marrow suppression is one of the most common, but spontaneous intracranial hemorrhage secondary to thrombocytopenia is rare. The present case report describes an 88-year-old man who presented with an intracranial hemorrhage after taking olanzapine for 2 weeks. This case emphasizes the importance of monitoring the potential adverse effects associated with olanzapine and other antipsychotics, especially in elderly patients.

Topics: Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Depressive Disorder; Humans; Intracranial Hemorrhages; Male; Olanzapine; Thrombocytopenia

Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Lithium Carbonate; Liver Function Tests; Neutropenia; Olanzapine; Retreatment; Thrombocytopenia; Valproic Acid

Topics: Aged; Antipsychotic Agents; Benzodiazepines; Fatal Outcome; Humans; Male; Olanzapine; Thrombocytopenia

Topics: Antipsychotic Agents; Benzodiazepines; Female; Humans; Leukocyte Count; Leukopenia; Middle Aged; Olanzapine; Pirenzepine; Schizophrenia, Paranoid; Thrombocytopenia

Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia