olanzapine and Lupus-Erythematosus--Discoid

Hypertrophic discoid lupus erythematosus is a distinct form of chronic cutaneous (discoid) lupus, which is characterized by hyperkeratotic plaques that typically are observed over the face, arms, and upper trunk. We present the case of a 43-year-old man with verrucous plaques that were distributed symmetrically over the face, who initially was treated with oral antibiotics and topical glucocorticoids for acne vulgaris. A biopsy specimen confirmed the diagnosis of hypertrophic discoid lupus erythematosus. The clinical and histopathologic features of this clinical variant are reviewed.

Topics: Acne Vulgaris; Adult; Anti-Bacterial Agents; Antipsychotic Agents; Benzodiazepines; Glucocorticoids; Humans; Lupus Erythematosus, Discoid; Male; Olanzapine; Schizoid Personality Disorder; Sertraline; Smoking; Treatment Outcome