okilactomycin has been researched along with Carcinoma--Ehrlich-Tumor* in 1 studies
1 other study(ies) available for okilactomycin and Carcinoma--Ehrlich-Tumor
| Article | Year |
|---|---|
Okilactomycin, a novel antibiotic produced by a Streptomyces species. I. Taxonomy, fermentation, isolation and characterization.
Okilactomycin, a novel antibiotic, was isolated from the culture filtrate of a strain of actinomycetes. The producing organism, strain YP-02908L, was identified as Streptomyces griseoflavus subsp. zamamiensis subsp. nov. The antibiotic was extracted with ethyl acetate and purified by silica gel column chromatography. It was obtained as colorless prisms from a dichloromethane solution. It exhibited weak antimicrobial activity against Ehrlich ascites carcinoma in vivo. The apparent molecular formula of okilactomycin was determined as C24H32O6. It is a new member of the lactone group antibiotics. Topics: Animals; Anti-Bacterial Agents; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Female; Injections, Intraperitoneal; Lactones; Mice; Neoplasms, Experimental | 1987 |