okaramine-b and Lyme-Disease

okaramine-b has been researched along with Lyme-Disease* in 1 studies

Other Studies

1 other study(ies) available for okaramine-b and Lyme-Disease

Article	Year
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease. International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2 A novel L-glutamate-gated anion channel (IscaGluCl1) has been cloned from the black-legged tick, Ixodes scapularis, which transmits multiple pathogens including the agents of Lyme disease and human granulocytic anaplasmosis. When mRNA encoding IscaGluCl1 was expressed in Xenopus laevis oocytes, we detected robust 50-400 nA currents in response to 100 μM L-glutamate. Responses to L-glutamate were concentration-dependent (pEC Topics: Abelmoschus; Acaricides; Animals; Azetidines; Azocines; Chloride Channels; Disease Vectors; Drug Discovery; Glutamic Acid; Indole Alkaloids; Ivermectin; Ixodes; Lyme Disease; Oocytes; Penicillium; Xenopus laevis	2018

Article

Year

The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.

International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2

A novel L-glutamate-gated anion channel (IscaGluCl1) has been cloned from the black-legged tick, Ixodes scapularis, which transmits multiple pathogens including the agents of Lyme disease and human granulocytic anaplasmosis. When mRNA encoding IscaGluCl1 was expressed in Xenopus laevis oocytes, we detected robust 50-400 nA currents in response to 100 μM L-glutamate. Responses to L-glutamate were concentration-dependent (pEC

Topics: Abelmoschus; Acaricides; Animals; Azetidines; Azocines; Chloride Channels; Disease Vectors; Drug Discovery; Glutamic Acid; Indole Alkaloids; Ivermectin; Ixodes; Lyme Disease; Oocytes; Penicillium; Xenopus laevis

2018