Page last updated: 2024-11-01

ofloxacin and Wounds and Injuries

ofloxacin has been researched along with Wounds and Injuries in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.

Research Excerpts

ExcerptRelevanceReference
"When used in partial thickness skin wounds on rats, only an extremely small amount of OFLX was detected in the serum, being higher under gel containing 2% OFLX."1.29Release of Ofloxacin from silicone gel sheet. ( Hatayama, I; Sawada, Y; Sone, K, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mailler-Savage, EA1
Neal, KW1
Godsey, T1
Adams, BB1
Gloster, HM1
Sawada, Y1
Hatayama, I1
Sone, K1

Trials

1 trial available for ofloxacin and Wounds and Injuries

ArticleYear
Is levofloxacin necessary to prevent postoperative infections of auricular second-intention wounds?
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2008, Volume: 34, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ear Auricle; Female; Humans; Levofloxacin; Male; Mid

2008

Other Studies

1 other study available for ofloxacin and Wounds and Injuries

ArticleYear
Release of Ofloxacin from silicone gel sheet.
    British journal of plastic surgery, 1993, Volume: 46, Issue:7

    Topics: Adolescent; Adult; Animals; Drug Implants; Female; Humans; In Vitro Techniques; Male; Middle Aged; O

1993