Page last updated: 2024-11-01

ofloxacin and Ventilator-Associated Pneumonia

ofloxacin has been researched along with Ventilator-Associated Pneumonia in 5 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The pharmacokinetics of levofloxacin and outcome of levofloxacin therapy in critically ill patients with ventilator-associated pneumonia (VAP) were assessed."7.74Pharmacokinetics and pharmacodynamics of levofloxacin in critically ill patients with ventilator-associated pneumonia. ( Benko, R; Doro, P; Gardi, J; Hajdu, E; Matuz, M; Molnar, A; Nagy, E; Peto, Z; Soos, G, 2007)
"The pharmacokinetics of levofloxacin and outcome of levofloxacin therapy in critically ill patients with ventilator-associated pneumonia (VAP) were assessed."3.74Pharmacokinetics and pharmacodynamics of levofloxacin in critically ill patients with ventilator-associated pneumonia. ( Benko, R; Doro, P; Gardi, J; Hajdu, E; Matuz, M; Molnar, A; Nagy, E; Peto, Z; Soos, G, 2007)
"Levofloxacin (200 mg/kg) was 73% effective, and ciprofloxacin (35 mg/kg) was ineffective in preventing death."1.39Assessment of the combination of doripenem plus a fluoroquinolone against non-susceptible Acinetobacter baumannii isolates from nosocomial pneumonia patients. ( Davies, TA; He, W; Lynch, AS; Queenan, AM, 2013)
"A 55 year-old male patient with chronic renal failure was hospitalized in intensive care unit following cardiopulmonary arrest."1.38[A case of ventilator-associated pneumonia due to Pantoea agglomerans]. ( Altın, N; Argun, C; Canbakan, B; Cesur, S; Koldaş, K; Kurşun, O; Sencan, I; Unal, N, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Queenan, AM1
Davies, TA1
He, W1
Lynch, AS1
Green, O1
Murray, P1
Gea-Banacloche, JC1
Hibbard, ML1
Kopelman, TR1
O'Neill, PJ1
Maly, TJ1
Matthews, MR1
Cox, JC1
Vail, SJ1
Quan, AN1
Drachman, DA1
Kurşun, O1
Unal, N1
Cesur, S1
Altın, N1
Canbakan, B1
Argun, C1
Koldaş, K1
Sencan, I1
Benko, R1
Matuz, M1
Doro, P1
Peto, Z1
Molnar, A1
Hajdu, E1
Nagy, E1
Gardi, J1
Soos, G1

Other Studies

5 other studies available for ofloxacin and Ventilator-Associated Pneumonia

ArticleYear
Assessment of the combination of doripenem plus a fluoroquinolone against non-susceptible Acinetobacter baumannii isolates from nosocomial pneumonia patients.
    Journal of chemotherapy (Florence, Italy), 2013, Volume: 25, Issue:3

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Carbapenems; Ciprofloxacin; Doripenem; D

2013
Sepsis caused by Elizabethkingia miricola successfully treated with tigecycline and levofloxacin.
    Diagnostic microbiology and infectious disease, 2008, Volume: 62, Issue:4

    Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Levofloxa

2008
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
    Surgical infections, 2010, Volume: 11, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug

2010
[A case of ventilator-associated pneumonia due to Pantoea agglomerans].
    Mikrobiyoloji bulteni, 2012, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Cefoperazone; Cross Infection; Drug Therapy, Combination; Enterobacteriaceae

2012
Pharmacokinetics and pharmacodynamics of levofloxacin in critically ill patients with ventilator-associated pneumonia.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Critical Illness; Female; Humans; Levofloxacin;

2007