Page last updated: 2024-11-01

ofloxacin and Vaginosis, Bacterial

ofloxacin has been researched along with Vaginosis, Bacterial in 5 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Vaginosis, Bacterial: Polymicrobial, nonspecific vaginitis associated with positive cultures of Gardnerella vaginalis and other anaerobic organisms and a decrease in lactobacilli. It remains unclear whether the initial pathogenic event is caused by the growth of anaerobes or a primary decrease in lactobacilli.

Research Excerpts

ExcerptRelevanceReference
"Uncomplicated pelvic inflammatory disease (PID) is a common disease caused by numerous pathogens: sexually transmitted infections (such as Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium), anaerobes, and other organisms from the vaginal flora."6.74Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study. ( Judlin, P; Thiebaugeorges, O, 2009)
"Women with clinically diagnosed cervicitis and BV received doxycycline and ofloxacin and were randomized to treatment with metronidazole gel or placebo."5.10Interrelationships of bacterial vaginosis and cervical inflammation. ( Schwebke, JR; Weiss, HL, 2002)
"Uncomplicated pelvic inflammatory disease (PID) is a common disease caused by numerous pathogens: sexually transmitted infections (such as Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium), anaerobes, and other organisms from the vaginal flora."2.74Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study. ( Judlin, P; Thiebaugeorges, O, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Judlin, P1
Thiebaugeorges, O1
Domingues, D1
Távora Tavira, L1
Duarte, A1
Sanca, A1
Prieto, E1
Exposto, F1
Chandeying, V1
Skov, S1
Kemapunmanus, M1
Law, M1
Geater, A1
Rowe, P1
Kane, KY1
Pierce, R1
Schwebke, JR1
Weiss, HL1

Reviews

1 review available for ofloxacin and Vaginosis, Bacterial

ArticleYear
Clinical inquiries. What are the most effective treatments for bacterial vaginosis in nonpregnant women?
    The Journal of family practice, 2001, Volume: 50, Issue:5

    Topics: Administration, Oral; Adult; Antifungal Agents; Clindamycin; Evidence-Based Medicine; Female; Guidel

2001

Trials

3 trials available for ofloxacin and Vaginosis, Bacterial

ArticleYear
Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study.
    European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 145, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Female; Humans; Levofloxacin; Metronidazole; Ofl

2009
Evaluation of two clinical protocols for the management of women with vaginal discharge in southern Thailand.
    Sexually transmitted infections, 1998, Volume: 74, Issue:3

    Topics: Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Clinical Protocols; Doxycycline; Female; Go

1998
Interrelationships of bacterial vaginosis and cervical inflammation.
    Sexually transmitted diseases, 2002, Volume: 29, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adult; Anti-Bacterial Agents; Anti-Infective Agents;

2002

Other Studies

1 other study available for ofloxacin and Vaginosis, Bacterial

ArticleYear
Genital mycoplasmas in women attending a family planning clinic in Guiné-Bissau and their susceptibility to antimicrobial agents.
    Acta tropica, 2003, Volume: 86, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Colony Count, Microbial; Drug Resistance, Bacterial; Drug Resistance,

2003