Page last updated: 2024-11-01

ofloxacin and Urinary Tract Infections

ofloxacin has been researched along with Urinary Tract Infections in 235 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.

Research Excerpts

ExcerptRelevanceReference
"Prulifloxacin is as effective and well tolerated as levofloxacin in the treatment of respiratory and urinary tract infections."9.16Prulifloxacin versus levofloxacin in the treatment of respiratory and urinary tract infections: a multicentre, double-blind, randomized controlled clinical trial. ( Chen, Y; Huang, W; Li, Q; Lu, G; Lv, X; Sun, Y; Wu, G; Wu, X; Wu, Y; Yang, H; Zhang, G, 2012)
"The aim of this study was to investigate the urinary bactericidal titers (UBTs) and 24-h area under the UBT-versus-time curve (AUBT) of intravenous doripenem (500 mg every 8 h [q8h]), a new carbapenem, versus those of intravenous levofloxacin (250 mg q24h) in patients with complicated urinary tract infections (cUTIs) or pyelonephritis."9.14Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis. ( Naber, KG; Redman, R; Wagenlehner, C; Wagenlehner, FM; Weidner, W, 2009)
"Doripenem was evaluated in adults with complicated urinary tract infections and pyelonephritis in two phase 3 studies."9.14Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis. ( Damiao, R; Davies, T; Kaniga, K; Kotey, P; Naber, KG; Redman, R, 2010)
"A clinical study was conducted to compare the efficacy and safety of levofloxacin 750 mg once daily for 5 days to ciprofloxacin twice daily for 10 days for the treatment of complicated urinary tract infections (cUTI) or acute pyelonephritis (AP)."9.13A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis. ( Fisher, AC; Kahn, JB; Kaul, S; Khashab, M; Peterson, J, 2008)
" This multicenter clinical study was designed to compare FRPM 300 mg 3 times daily to Levofloxacin (LVFX), which is the standard treatment for patients with UTI, 100 mg 3 times daily for 7 days in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy."9.10[Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy]. ( Fujimoto, N; Iihara, K; Inatomi, H; Kobayashi, T; Matsumoto, T; Muratani, T; Nishimura, T; Takahashi, K; Yamada, Y, 2002)
"The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections."9.10[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003)
"Forty two paraplegic and quadriplegic hospitalized spinal cord injured patients with urinary tract infections (UTI) were included in a double blind, randomized treatment study comparing 7 days ofloxacin (300 mg bd) with trimethoprim-sulphamethoxazole (TMPSMX; 160-800 mg bd) or an alternative, chosen because of resistance to TMPSMX."9.09Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury. ( Delaney, G; Hayes, K; Hsieh, J; Nicosia, S; Potter, P; Reid, G, 2000)
"Levofloxacin, the optical S-(-) isomer of ofloxacin, was compared with ofloxacin in the treatment of complicated urinary tract infections (UTIs)."9.09Randomized, double-blind, comparative study of levofloxacin and ofloxacin in the treatment of complicated urinary tract infections. ( Peng, MY, 1999)
"This double-blind randomized study compared 3-day regimens of cefixime (400 mg once daily) and ofloxacin (200 mg twice a day) in the treatment of urinary tract infections in women."9.07Double-blind study comparing 3-day regimens of cefixime and ofloxacin in treatment of uncomplicated urinary tract infections in women. ( Leshem, Y; Raz, R; Rottensterich, E; Tabenkin, H, 1994)
"In order to reduce the dosage of aminoglycoside in the treatment of patients with complicated urinary tract infections (UTI) in outpatient clinics and to improve cost benefits, we tried both ofloxacin (OFX) treatment and a combination treatment with OFX and a single dose of aminoglycoside (isepamicin)."9.07Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside. ( Eto, K; Ishii, T; Kumazawa, J; Matsumoto, T; Saito, Y; Sawae, Y; Ueda, S; Yushita, Y, 1991)
"Studies of ofloxacin pharmacokinetics and pathogen susceptibilities suggested that this new fluoroquinolone might be particularly well suited to the treatment of urinary tract infections and prostatitis."9.06Ofloxacin in the management of complicated urinary tract infections, including prostatitis. ( Cox, CE, 1989)
"A single dose of 100 mg ofloxacin was compared with a multiple dose of cotrimoxazole in lower urinary tract infections in 137 women."9.06Failure of a single dose of 100 mg ofloxacin in lower urinary tract infections in females. ( Forsgren, A; Ode, B; Walder, M, 1987)
"The efficacies of ofloxacin and norfloxacin in the treatment of chronic complicated urinary tract infections were compared."9.06Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections. ( Rugendorff, EW, 1987)
"A simple open randomized study was performed to evaluate the comparative efficacy and safety of ofloxacin and cotrimoxazole in 40 patients with complicated urinary tract infections."9.06Ofloxacin vs. cotrimoxazole in patients with complicated urinary tract infections. ( Battaglia, AM; Battaglia, P; Bernardini, G; Vellucci, A, 1987)
"A multicenter trial on the efficacy and tolerability of ofloxacin in upper and lower respiratory tract infections and urinary tract infections was carried out on 1,436 patients (926 males and 510 females; mean age 55."9.06A multicenter study on clinical efficacy of ofloxacin in respiratory and urinary tract infections. ( Grassi, GG, 1986)
"Ofloxacin was administered to 18 patients and ciprofloxacin to 17 patients suffering from acute or chronic complicated urinary tract infections."9.06Clinical evaluation of ofloxacin versus ciprofloxacin in complicated urinary tract infections. ( Kromann-Andersen, B; Larsen, V; Pers, C; Rasmussen, F; Sommer, P, 1986)
"The clinical efficacy, safety and usefulness of DL-8280 for the treatment of complicated urinary tract infections were compared with those of pipemidic acid (PPA) by a double-blind method."9.05[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method]. ( Deguchi, K; Fujita, Y; Kishi, H; Niijima, T; Nishimura, Y; Nito, H; Ogawa, N; Ohmori, H; Saito, I; Tanaka, H, 1984)
"ofloxacin has established efficacy in the treatment of a wide variety of urinary tract infections, although, like other fluoroquinolones, it should be used rationally to preserve its activity."8.80Ofloxacin. A reappraisal of its use in the management of genitourinary tract infections. ( Balfour, JA; Lamb, HM; Onrust, SV, 1998)
"We evaluated, by Monte Carlo simulation, 500-mg once-daily, 100-mg thrice-daily, 200-mg twice-daily, and 200-mg thrice-daily dose regimens of levofloxacin (LVFX), for the ratio of area under the concentration-time curve for 24 h (AUC(0-24)) to minimum inhibitory concentration (MIC) (AUC(0-24)/MIC) and the ratio of maximum plasma concentration (C(max)) to MIC (C(max)/MIC), which predict microbiological outcomes, and the C(max)/MIC, which inhibits fluoroquinolone resistance selection, in complicated urinary tract infections (UTIs) with Escherichia coli or Pseudomonas aeruginosa."7.77Evaluation by Monte Carlo simulation of levofloxacin dosing for complicated urinary tract infections caused by Escherichia coli or Pseudomonas aeruginosa. ( Deguchi, T; Matsumoto, T; Seike, K; Yasuda, M, 2011)
"The pharmacodynamic targets representing 90% probability thresholds for bacterial eradication were determined in patients with complicated urinary tract infections (UTIs) treated with 500mg of levofloxacin every 24h for 7-14 days."7.76Microbiological outcome of complicated urinary tract infections treated with levofloxacin: a pharmacokinetic/pharmacodynamic analysis. ( Arakawa, S; Deguchi, T; Matsumoto, T; Monden, K; Nakane, K; Shimizu, T; Yasuda, M, 2010)
"Minimum inhibitory concentrations (MICs) and mutant prevention concentrations (MPCs) of prulifloxacin against 30 strains of Escherichia coli isolated from urinary tract infections as well as the 'biological cost' related to acquisition of resistance to the same drug in 10 uropathogenic E."7.74In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance. ( Gualco, L; Marchese, A; Schito, AM; Schito, GC, 2007)
"The aim of this study was to evaluate the in vitro activity of levofloxacin (LVX) in comparison to nalidixic acid (NAL), ofloxacin (OFX), norfloxacin (NOR), amoxicillin (AMX), cefixime (CFM), cotrimoxazole (SXT) and nitrofurantoin (FT), against 402 strains recently isolated from urine specimens in outpatient women suffering from lower urinary tract infections for which short-term treatment was not indicated."7.73[Evaluation of levofloxacin susceptibility against strains isolated from lower urinary tract infections in the community]. ( Dib, C; Durand, C; Moniot-Ville, N; Weber, P, 2005)
"Twenty patients with urinary tuberculosis were treated with ofloxacin (200 mg/day, 6 months), rifampin (600 mg/day, 3 months) and isoniazid (300 mg/day, 3 months) between 1989 and 1990."7.71Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study. ( Castiñeiras, AA; Della-Latta, P; Herreras, A; Pérez-Pascual, P; Zarranz, JE, 2002)
"The clinical efficacy of a single-day oral administration of levofloxacin (LVFX) for the prevention of urinary tract infections (UTI) after urogenital examinations and treatments for outpatients was assessed."7.71[Efficacy of a single-day administration of levofloxacin for the prevention of urinary tract infections after urogenital examinations and treatments for outpatients]. ( Arai, G; Hayashi, T; Hyochi, N; Kageyama, Y; Kawakami, S; Kihara, K; Kobayashi, T; Masuda, H; Okuno, T; Saito, K; Sakai, Y; Suzuki, M, 2001)
"Minimum inhibitory concentrations (MICs) of gatifloxacin were compared with those of gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin using an agar dilution method for 400 uropathogens cultured from the urine of urological patients with complicated and/or hospital-acquired urinary tract infections (UTI)."7.70In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections. ( Hollauer, K; Kirchbauer, D; Naber, KG; Witte, W, 2000)
"The minimal inhibitory concentrations (MIC) of ofloxacin against 400 isolates cultured from the urine of urological patients with complicated urinary tract infections (UTI) resulted in an inhibition of 94% (99%) of the gram-negative strains at a concentration of 1 mg/l (2 mg/l) and an inhibition of 59% (100%) of the gram-positive strains at a concentration of 1 mg/l (4 mg/l)."7.67[In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections]. ( Adam, D; Bartosik-Wich, B; Naber, KG; Wittenberger, R, 1986)
"The clinical efficacy of the new quinolone antibacterial agent ofloxacin (OFLX) on urinary tract infections (UTI) was reevaluated."7.67[Clinical reevaluation of ofloxacin (OFLX) in urinary tract infections]. ( Akiyama, T; Kurita, T; Matsuura, T, 1988)
"To study the treatment effects of ofloxacin (OFLX) on the patients with complicated urinary tract infections (UTI), OFLX at a daily dose of 600 mg divided into either two or three doses per day, was administered for 14 days to 114 patients with complicated UTI."7.67[Treatment of complicated urinary tract infections by ofloxacin]. ( Horiuchi, S; Kaneoya, F; Kojima, S; Nakame, Y; Negishi, T; Saitoh, H; Satake, I; Takahashi, T; Tari, K; Yoshida, K, 1988)
"In this study the in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections was examined."7.67[The in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections]. ( Tunçkanat, F; Yuluğ, N, 1988)
"During 1984 to 1988, 35 patients with urinary tract infection (UTI) and 37 patients with enteric fever were treated successfully with 400 mg ofloxacin twice a day for 7 to 10 days."7.67In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever. ( Srimuang, S; Tanphaichitra, D, 1988)
"Fifty-three patients with urinary tract infections (UTI) were treated with Ofloxacin, a new oral synthetic antimicrobial agent, and its clinical efficacy was studied."7.67[Clinical study of ofloxacin (OFLX) on urinary tract infections]. ( Inada, F; Inagaki, N; Miyata, M; Mizunaga, M; Morikawa, M; Okamura, K; Osanai, H; Yachiku, S, 1987)
"Clinical efficacy of ofloxacin (OFLX) against complicated urinary tract infections was examined in 20 patients."7.67[Clinical evaluation of ofloxacin against complicated urinary tract infections]. ( Nishio, S; Yoshihara, H, 1987)
"Doripenem was found not to be inferior to levofloxacin in terms of therapeutics and is now approved for use in the United States and Europe for the treatment of adults with cUTI, including pyelonephritis."6.74Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis. ( Hedrich, D; Kaniga, K; Kotey, P; Llorens, L; Naber, KG; Redman, R, 2009)
" This study concluded that the dosage regimen of LVFX 500 mg once daily was effective and tolerable for the treatment of LRTIs and UTIs."6.74Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China. ( Chen, BY; Ding, GH; Duan, J; Gu, JM; Guo, DY; Hao, QL; Huang, HH; Huang, JA; Li, HY; Li, QH; Liu, A; Lü, XJ; Ma, H; Ren, ZY; Shen, HH; Shi, MH; Si, B; Sun, SH; Sun, TY; Wu, GM; Xia, QM; Xiao, W; Xiao, ZK; Xiu, QY; Yang, HF; Yang, HP; Yao, WZ; Ying, KJ; Yu, YS; Yue, HM; Zhang, W; Zhang, YY; Zheng, HG, 2009)
"The study shows that it is possible to treat complicated urinary tract infections just as successfully with 200 mg i."6.67Comparison of i.v. ofloxacin and piperacillin in the treatment of complicated urinary tract infections. ( Schalkhäuser, K, 1990)
"Levofloxacin is a second generation fluoroquinolone with a post marketing history of well tolerated and successful use in a variety of clinical situations."6.41A risk-benefit assessment of levofloxacin in respiratory, skin and skin structure, and urinary tract infections. ( Garvin, CG; Jung, R; Martin, SJ, 2001)
"Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12."5.28[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992)
"Ofloxacin can cause retarded ossification and arthropathy in young animals, but there is no published information about its teratogenicity in humans."5.28Ofloxacin during the second trimester of pregnancy. ( Friedman, S; Hod, M; Merlob, P; Peled, Y, 1991)
"An analysis of subjects with concurrent bacteraemia and either nosocomial pneumonia, complicated intra-abdominal infection or complicated urinary tract infection from six phase 3 clinical trials demonstrated similar cure rates and clearance of bacteraemia in patients treated with doripenem and comparator agents."5.17Activity of doripenem versus comparators in subjects with baseline bacteraemia in six pooled phase 3 clinical trials. ( Kaniga, K; Lee, M; Redman, R; Rice, DA, 2013)
"Prulifloxacin is as effective and well tolerated as levofloxacin in the treatment of respiratory and urinary tract infections."5.16Prulifloxacin versus levofloxacin in the treatment of respiratory and urinary tract infections: a multicentre, double-blind, randomized controlled clinical trial. ( Chen, Y; Huang, W; Li, Q; Lu, G; Lv, X; Sun, Y; Wu, G; Wu, X; Wu, Y; Yang, H; Zhang, G, 2012)
"The aim of this study was to investigate the urinary bactericidal titers (UBTs) and 24-h area under the UBT-versus-time curve (AUBT) of intravenous doripenem (500 mg every 8 h [q8h]), a new carbapenem, versus those of intravenous levofloxacin (250 mg q24h) in patients with complicated urinary tract infections (cUTIs) or pyelonephritis."5.14Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis. ( Naber, KG; Redman, R; Wagenlehner, C; Wagenlehner, FM; Weidner, W, 2009)
"Doripenem was evaluated in adults with complicated urinary tract infections and pyelonephritis in two phase 3 studies."5.14Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis. ( Damiao, R; Davies, T; Kaniga, K; Kotey, P; Naber, KG; Redman, R, 2010)
"A clinical study was conducted to compare the efficacy and safety of levofloxacin 750 mg once daily for 5 days to ciprofloxacin twice daily for 10 days for the treatment of complicated urinary tract infections (cUTI) or acute pyelonephritis (AP)."5.13A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis. ( Fisher, AC; Kahn, JB; Kaul, S; Khashab, M; Peterson, J, 2008)
"The objective of this multicenter, randomized, controlled, parallel group trial was to evaluate the efficacy of levofloxacin 250 mg oral, once daily (LVFX), placebo one tablet oral once daily (Placebo [P] group) and ciprofloxacin (CPFX) 500 mg oral, twice daily (single blind), prophylaxis in preventing bacteriuria (> or = 10(3) CFU/ml) in post-surgical catheterized patients."5.12A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones. ( Drago, L; Esposito, S; Leone, S; Marchetti, F; Marvaso, A; Noviello, S, 2006)
" Overall bacteriuria rate at day 5 to 7 was 22% (levofloxacin 21%; TMP/SMZ 20%; control group 30%)."5.11Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate. ( Naber, KG; Schinzel, S; Wagenlehner, C; Wagenlehner, FM, 2005)
" This multicenter clinical study was designed to compare FRPM 300 mg 3 times daily to Levofloxacin (LVFX), which is the standard treatment for patients with UTI, 100 mg 3 times daily for 7 days in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy."5.10[Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy]. ( Fujimoto, N; Iihara, K; Inatomi, H; Kobayashi, T; Matsumoto, T; Muratani, T; Nishimura, T; Takahashi, K; Yamada, Y, 2002)
"The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections."5.10[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003)
"Forty two paraplegic and quadriplegic hospitalized spinal cord injured patients with urinary tract infections (UTI) were included in a double blind, randomized treatment study comparing 7 days ofloxacin (300 mg bd) with trimethoprim-sulphamethoxazole (TMPSMX; 160-800 mg bd) or an alternative, chosen because of resistance to TMPSMX."5.09Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury. ( Delaney, G; Hayes, K; Hsieh, J; Nicosia, S; Potter, P; Reid, G, 2000)
" They were compared with 23 acute pyelonephritis patients given ciprofloxacin in a dose 1 g/day."5.09[Tavanik effectiveness and safety in the treatment of urinary tract infection complications]. ( Loran, OB; Pushkar', DIu; Rasner, PI, 2001)
"The efficacy and safety of ofloxacin in the treatment of upper and lower urinary tract infections were studied with the drug use according to 4 regimens by comparison with nitrofurantoin in the treatment of lower urinary tract infections and trimethoprim/sulfamethoxazole in the treatment of upper urinary tract infections."5.08[Clinical experience with the use of ofloxacin in infections of the upper and lower urinary tracts: demonstrations of the results of clinical trials]. ( Liudvig, G, 1996)
"The efficacy and safety of levofloxacin and lomefloxacin in complicated urinary tract infections (UTIs) were compared in a randomized, open-label, multicenter study."5.08A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection. ( Callery-D'Amico, S; Cox, CE; Fowler, CL; Kim, SS; King, W; Klimberg, IW, 1998)
"The efficacy and safety of a 3-day regimen of sparfloxacin were compared with those of a 3-day regimen of ofloxacin for the treatment of community-acquired acute uncomplicated urinary tract infections."5.08Treatment of community-acquired acute uncomplicated urinary tract infection with sparfloxacin versus ofloxacin. The Sparfloxacin Multi Center UUTI Study Group. ( Dorr, MB; Ellison, W; Henry, D; Magner, DJ; Mansfield, DL; Sullivan, J; Talbot, GH, 1998)
"This double-blind randomized study compared 3-day regimens of cefixime (400 mg once daily) and ofloxacin (200 mg twice a day) in the treatment of urinary tract infections in women."5.07Double-blind study comparing 3-day regimens of cefixime and ofloxacin in treatment of uncomplicated urinary tract infections in women. ( Leshem, Y; Raz, R; Rottensterich, E; Tabenkin, H, 1994)
"A total of 125 ambulatory women (85 premenopausal and 40 postmenopausal) who experienced 174 acute urinary tract infections with mainly gram-negative bacteria (99%) was randomized to receive a single dose, 2-tablet treatment with either ofloxacin (400 mg."5.07Single dose quinolone treatment in acute uncomplicated urinary tract infection in women. ( Pfau, A; Sacks, TG, 1993)
"The efficacy and safety of ofloxacin for the treatment of pneumonia, urinary infection and skin infections in the institutionalized elderly is being studied in a multicenter North American trial."5.07Ofloxacin use in a geriatric population. ( Alessi, P; Cullison, J; Degelau, J; Meyers, B; Nicolle, LE, 1991)
"In order to reduce the dosage of aminoglycoside in the treatment of patients with complicated urinary tract infections (UTI) in outpatient clinics and to improve cost benefits, we tried both ofloxacin (OFX) treatment and a combination treatment with OFX and a single dose of aminoglycoside (isepamicin)."5.07Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside. ( Eto, K; Ishii, T; Kumazawa, J; Matsumoto, T; Saito, Y; Sawae, Y; Ueda, S; Yushita, Y, 1991)
"Studies of ofloxacin pharmacokinetics and pathogen susceptibilities suggested that this new fluoroquinolone might be particularly well suited to the treatment of urinary tract infections and prostatitis."5.06Ofloxacin in the management of complicated urinary tract infections, including prostatitis. ( Cox, CE, 1989)
"The drug Ofloxacin was tried clinically on 54 patients with different bacterial infections."5.06[Clinical trial of ofloxacin (Tarivid R)]. ( Angelova, I; Belovezhdov, N; Talakova, Ch, 1988)
"A single dose of 100 mg ofloxacin was compared with a multiple dose of cotrimoxazole in lower urinary tract infections in 137 women."5.06Failure of a single dose of 100 mg ofloxacin in lower urinary tract infections in females. ( Forsgren, A; Ode, B; Walder, M, 1987)
"The efficacies of ofloxacin and norfloxacin in the treatment of chronic complicated urinary tract infections were compared."5.06Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections. ( Rugendorff, EW, 1987)
"A simple open randomized study was performed to evaluate the comparative efficacy and safety of ofloxacin and cotrimoxazole in 40 patients with complicated urinary tract infections."5.06Ofloxacin vs. cotrimoxazole in patients with complicated urinary tract infections. ( Battaglia, AM; Battaglia, P; Bernardini, G; Vellucci, A, 1987)
"A multicenter trial on the efficacy and tolerability of ofloxacin in upper and lower respiratory tract infections and urinary tract infections was carried out on 1,436 patients (926 males and 510 females; mean age 55."5.06A multicenter study on clinical efficacy of ofloxacin in respiratory and urinary tract infections. ( Grassi, GG, 1986)
" regarding the safety and efficacy of ofloxacin in the treatment of urinary tract infections are presented."5.06Clinical experience with ofloxacin in urinary tract infection. ( Callery, SV; Cox, CE; Tack, KJ, 1986)
"Ofloxacin was administered to 18 patients and ciprofloxacin to 17 patients suffering from acute or chronic complicated urinary tract infections."5.06Clinical evaluation of ofloxacin versus ciprofloxacin in complicated urinary tract infections. ( Kromann-Andersen, B; Larsen, V; Pers, C; Rasmussen, F; Sommer, P, 1986)
"The clinical efficacy, safety and usefulness of DL-8280 for the treatment of complicated urinary tract infections were compared with those of pipemidic acid (PPA) by a double-blind method."5.05[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method]. ( Deguchi, K; Fujita, Y; Kishi, H; Niijima, T; Nishimura, Y; Nito, H; Ogawa, N; Ohmori, H; Saito, I; Tanaka, H, 1984)
"Levofloxacin and sparfloxacin are active against pathogens frequently involved in community-acquired upper and lower respiratory tract infections, including Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Legionella pneumophila, and Chlamydia pneumoniae."4.80Levofloxacin and sparfloxacin: new quinolone antibiotics. ( Chuck, SK; Jung, R; Martin, SJ; Messick, CR; Meyer, JM; Pendland, SL, 1998)
"ofloxacin has established efficacy in the treatment of a wide variety of urinary tract infections, although, like other fluoroquinolones, it should be used rationally to preserve its activity."4.80Ofloxacin. A reappraisal of its use in the management of genitourinary tract infections. ( Balfour, JA; Lamb, HM; Onrust, SV, 1998)
"We evaluated, by Monte Carlo simulation, 500-mg once-daily, 100-mg thrice-daily, 200-mg twice-daily, and 200-mg thrice-daily dose regimens of levofloxacin (LVFX), for the ratio of area under the concentration-time curve for 24 h (AUC(0-24)) to minimum inhibitory concentration (MIC) (AUC(0-24)/MIC) and the ratio of maximum plasma concentration (C(max)) to MIC (C(max)/MIC), which predict microbiological outcomes, and the C(max)/MIC, which inhibits fluoroquinolone resistance selection, in complicated urinary tract infections (UTIs) with Escherichia coli or Pseudomonas aeruginosa."3.77Evaluation by Monte Carlo simulation of levofloxacin dosing for complicated urinary tract infections caused by Escherichia coli or Pseudomonas aeruginosa. ( Deguchi, T; Matsumoto, T; Seike, K; Yasuda, M, 2011)
"We examined Enterococcus faecalis strains clinically isolated from 100 patients with urinary tract infections (UTIs) for their susceptibility to levofloxacin (LVX) by measuring the MIC and investigated amino acid mutations by direct DNA sequencing, which were then correlated with LVX resistance."3.77Mechanisms of and risk factors for fluoroquinolone resistance in clinical Enterococcus faecalis isolates from patients with urinary tract infections. ( Arakawa, S; Fujisawa, M; Kawabata, M; Matsumoto, M; Nakano, Y; Shigemura, K; Shirakawa, T; Tanaka, K; Yasufuku, T, 2011)
"The pharmacodynamic targets representing 90% probability thresholds for bacterial eradication were determined in patients with complicated urinary tract infections (UTIs) treated with 500mg of levofloxacin every 24h for 7-14 days."3.76Microbiological outcome of complicated urinary tract infections treated with levofloxacin: a pharmacokinetic/pharmacodynamic analysis. ( Arakawa, S; Deguchi, T; Matsumoto, T; Monden, K; Nakane, K; Shimizu, T; Yasuda, M, 2010)
"Because of high rates of trimethoprim-sulfamethoxazole resistance in Escherichia coli, Denver Health switched to levofloxacin as the initial therapy for urinary tract infections (UTIs) in 1999."3.74Emergence of fluoroquinolone resistance in outpatient urinary Escherichia coli isolates. ( Burman, WJ; Everhart, RM; Johnson, L; MacKenzie, TD; Mehler, PS; Price, CS; Rome, M; Rozwadowski, J; Sabel, A, 2008)
"Minimum inhibitory concentrations (MICs) and mutant prevention concentrations (MPCs) of prulifloxacin against 30 strains of Escherichia coli isolated from urinary tract infections as well as the 'biological cost' related to acquisition of resistance to the same drug in 10 uropathogenic E."3.74In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance. ( Gualco, L; Marchese, A; Schito, AM; Schito, GC, 2007)
"The aim of this study was to evaluate the in vitro activity of levofloxacin (LVX) in comparison to nalidixic acid (NAL), ofloxacin (OFX), norfloxacin (NOR), amoxicillin (AMX), cefixime (CFM), cotrimoxazole (SXT) and nitrofurantoin (FT), against 402 strains recently isolated from urine specimens in outpatient women suffering from lower urinary tract infections for which short-term treatment was not indicated."3.73[Evaluation of levofloxacin susceptibility against strains isolated from lower urinary tract infections in the community]. ( Dib, C; Durand, C; Moniot-Ville, N; Weber, P, 2005)
"Comparative susceptibility of microflora isolates from patients with complicated urinary tract infections to cefepime, other cephalosporins, amikacin, ciprofloxacin and ofloxacin was studied."3.72[Cefepime (maxipime) in the treatment of severe urinary tract infection]. ( Derevianko, II, 2003)
"Twenty patients with urinary tuberculosis were treated with ofloxacin (200 mg/day, 6 months), rifampin (600 mg/day, 3 months) and isoniazid (300 mg/day, 3 months) between 1989 and 1990."3.71Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study. ( Castiñeiras, AA; Della-Latta, P; Herreras, A; Pérez-Pascual, P; Zarranz, JE, 2002)
"We studied gastrointestinal (GI) colonization by Candida albicans in patients receiving oral norfloxacin, ciprofloxacin or ofloxacin as monotherapy for urinary tract infections."3.71The impact of norfloxacin, ciprofloxacin and ofloxacin on human gut colonization by Candida albicans. ( Cranidis, A; Kontoyiannis, DP; Maraki, S; Mavromanolakis, E; Samonis, G; Tselentis, Y, 2001)
"When seven elderly patients with fever due to bacterial infection failed to respond to ofloxacin 300 mg/day for 3 days, we prescribed Mao-bushi-saishin-to for 7 days."3.70Effect of Mao-bushi-saishin-to on infection of ofloxacin resistant bacteria and of unknown origin. ( Kamei, T; Tomioka, H; Toriumi, Y, 2000)
"The efficacy of single dose ofloxacin in lower urinary tract infections was investigated in this study."3.68Single dose of ofloxacin treatment in women with dysuria and frequency. ( Akdaş, A; Dillioğlugil, O; Ilker, Y; Simşek, F, 1993)
"The effects of orally administered ofloxacin on functional parameters of cell-mediated immunity were investigated in 15 patients with respiratory or urinary tract infections."3.68Effects of ofloxacin on cell-mediated immune response and lymphokine production. ( Arpinelli, F; Benedetti, M; Biglino, A; Busso, M; Forno, B; Pollono, AM; Pugliese, A, 1990)
"The minimal inhibitory concentrations (MIC) of ofloxacin against 400 isolates cultured from the urine of urological patients with complicated urinary tract infections (UTI) resulted in an inhibition of 94% (99%) of the gram-negative strains at a concentration of 1 mg/l (2 mg/l) and an inhibition of 59% (100%) of the gram-positive strains at a concentration of 1 mg/l (4 mg/l)."3.67[In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections]. ( Adam, D; Bartosik-Wich, B; Naber, KG; Wittenberger, R, 1986)
" Among quinolones, the most active agents are ciprofloxacin and ofloxacin (MIC modes: 4 and 2 mg/l), so these antimicrobials could be used for the treatment of urinary tract infections caused by Corynebacterium group D2."3.67[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity]. ( Cancet, B; Clave, D; Didier, J; Henry-Ferry, S; Marty, N, 1988)
"The therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 was compared in alloxan-induced diabetic mice with experimental respiratory and urinary tract infections."3.67Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice. ( Nishino, T; Obana, Y, 1988)
"During 1984 to 1988, 35 patients with urinary tract infection (UTI) and 37 patients with enteric fever were treated successfully with 400 mg ofloxacin twice a day for 7 to 10 days."3.67In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever. ( Srimuang, S; Tanphaichitra, D, 1988)
" It was used alone 26 times and on 6 occasions it was associated with rifampin on 6 staphylococcal infections."3.67[Ofloxacin (RU 43280). Clinical study]. ( Bertrand, A; Despaux, E; Janbon, F; Jonquet, O; Reynes, J, 1987)
"Fifty-three patients with urinary tract infections (UTI) were treated with Ofloxacin, a new oral synthetic antimicrobial agent, and its clinical efficacy was studied."3.67[Clinical study of ofloxacin (OFLX) on urinary tract infections]. ( Inada, F; Inagaki, N; Miyata, M; Mizunaga, M; Morikawa, M; Okamura, K; Osanai, H; Yachiku, S, 1987)
"Ofloxacin, a new fluoroquinolone, was given to fifty patients (29 females and 21 males) aged 25 to 86 years with urinary tract infection or prostatitis."3.67[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections]. ( Acar, JF; Guibert, J, 1986)
"A treatment with ofloxacin for 7 days was inferior to 14 days for febrile UTI in men and should therefore not be recommended."3.30Antimicrobial for 7 or 14 Days for Febrile Urinary Tract Infection in Men: A Multicenter Noninferiority Double-Blind, Placebo-Controlled, Randomized Clinical Trial. ( Abgrall, S; Aparicio, C; Aumaitre, H; Bercot, B; Bernard, L; Bourgarit-Durand, A; Bruyere, F; Canoui, E; Chabrol, A; Charlier, C; Chevret, S; de Lastours, V; Desseaux, K; Empana-Barat, F; Escaut, L; Etienne, M; Ferreyra, M; Fontaine, JP; Garrait, V; Gatey, C; Grall, N; Jaureguiberry, S; Lafaurie, M; Lefort, A; Madeleine, I; Meyssonnier, V; Molina, JM; Mongiat-Artus, P; Morrier, M; Pacanowski, J; Piet, E; Talarmin, JP, 2023)
"Doripenem was found not to be inferior to levofloxacin in terms of therapeutics and is now approved for use in the United States and Europe for the treatment of adults with cUTI, including pyelonephritis."2.74Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis. ( Hedrich, D; Kaniga, K; Kotey, P; Llorens, L; Naber, KG; Redman, R, 2009)
" This study concluded that the dosage regimen of LVFX 500 mg once daily was effective and tolerable for the treatment of LRTIs and UTIs."2.74Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China. ( Chen, BY; Ding, GH; Duan, J; Gu, JM; Guo, DY; Hao, QL; Huang, HH; Huang, JA; Li, HY; Li, QH; Liu, A; Lü, XJ; Ma, H; Ren, ZY; Shen, HH; Shi, MH; Si, B; Sun, SH; Sun, TY; Wu, GM; Xia, QM; Xiao, W; Xiao, ZK; Xiu, QY; Yang, HF; Yang, HP; Yao, WZ; Ying, KJ; Yu, YS; Yue, HM; Zhang, W; Zhang, YY; Zheng, HG, 2009)
"Prostate cancer was present in 93 patients (23%)."2.70Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk. ( Ali-Khan, MM; Canby-Hagino, E; Foley, JP; Griffith, BC; Morey, AF; Rozanski, TA, 2002)
" This pharmacokinetic modeling could be used to determine optimal treatment dose in clinical trials in a shorter time frame with fewer patients."2.69Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials. ( Berman, AL; Chow, AT; Corrado, M; Dornseif, B; Drusano, GL; Fowler, CL; Natarajan, J; Preston, SL; Reichl, V, 1998)
"Ofloxacin was well tolerated: adverse events were reported by 67 (12."2.67Ofloxacin versus trimethoprim and co-trimoxazole in the treatment of uncomplicated urinary tract infection in general practice. ( Cole, TP; Spencer, RC, 1992)
"The present study was undertaken to evaluate the clinical efficacy of long-term administration of ofloxacin (OFLX) to the patients following transurethral resection of the prostate."2.67[Study of the long-term administration of ofloxacin to the patients following transurethral resection of the prostate]. ( Hasuda, A; Morita, M; Suzuki, K, 1991)
" A treatment course of ofloxacin, once-a-day for three days, was as safe and effective as a standard course of TMP/SMX, twice a day for seven days."2.67Randomized study to evaluate efficacy and safety of ofloxacin vs. trimethoprim and sulfamethoxazole in treatment of uncomplicated urinary tract infection. ( Basista, MP, 1991)
"Ofloxacin was administered orally at a daily dosage of 300 mg and 600 mg in three divided doses for 14 days to 24 and 60 patients with chronic complicated urinary infections, respectively, in order to evaluate the therapeutic efficacy."2.67[Clinical evaluation of ofloxacin in the treatment of chronic complicated urinary tract infection]. ( Hisazumi, H; Kobashi, K; Koizumi, H; Motoi, I; Nagano, K; Nishino, A; Orito, M; Sawaki, M; Shyoda, R; Uchibayashi, T, 1990)
"Ofloxacin treatment was used for the treatment of lower respiratory tract infections in 35 patients."2.67Severe infections treated with intravenous ofloxacin: a prospective clinical multicentre Swiss study. ( Regamey, C; Steinbach-Lebbin, C, 1990)
" Dosage adjustment was made for patients in renal failure."2.67Efficacy of intravenous ofloxacin: a French multicentre trial in 185 patients. ( Beaucaire, G; Beuscart, C; Chidiac, C; Leroy, O; Mouton, Y; Senneville, E; Sivery, B; Vincent du Laurier, M, 1990)
"The study shows that it is possible to treat complicated urinary tract infections just as successfully with 200 mg i."2.67Comparison of i.v. ofloxacin and piperacillin in the treatment of complicated urinary tract infections. ( Schalkhäuser, K, 1990)
"Ofloxacin was administered in three different dosages in order to evaluate drug efficacy and tolerance: 600 mg/day for 3 days in 22 cases; 300 mg/day for 3 days in 22 cases; 600 mg/day for 5 days in 1 case."2.66[Use of ofloxacin in 45 cases of infection of the lower urinary tract in women]. ( Bottino, G; Marinello, M; Menna, C; Vergano, RM, 1989)
"Ofloxacin was also effective in the treatment of enteric fever, in which eradication was achieved in all seven patients."2.66Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections. ( Sahaphong, S; Srimuang, S; Tanphaichitra, D, 1986)
"Ofloxacin is a new quinolone-carboxylic acid derivative with a broad spectrum of activity, excellent bioavailability after oral administration and insignificant metabolisation."2.66[Summarized results of clinical phase II and III studies with ofloxacin (HOE 280) in Europe]. ( Blomer, R; Bruch, K; Zahlten, RN, 1986)
"Renal parenchymal malacoplakia is a rare cause of acute renal failure."2.42Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature. ( Chan, KW; Kung, WH; Li, R; Tam, VK, 2003)
" Many of the fluoroquinolone agents have once-daily dosing regimens, enhancing patient adherence."2.41The expanding role of fluoroquinolones. ( Schaeffer, AJ, 2002)
"Levofloxacin is a second generation fluoroquinolone with a post marketing history of well tolerated and successful use in a variety of clinical situations."2.41A risk-benefit assessment of levofloxacin in respiratory, skin and skin structure, and urinary tract infections. ( Garvin, CG; Jung, R; Martin, SJ, 2001)
"Oral levofloxacin was also similar in efficacy to amoxicillin/clavulanic acid or oral clarithromycin in patients with acute maxillary sinusitis treated for 7 to 14 days."2.40Levofloxacin. Its use in infections of the respiratory tract, skin, soft tissues and urinary tract. ( Lamb, HM; Langtry, HD, 1998)
"Ofloxacin is a quinolone carboxylic acid with a broad spectrum of activity for gram-negative pathogens that are common causes of urologic infections including cystitis, pyelonephritis, and prostatitis."2.38Worldwide clinical experience with ofloxacin in urologic cases. ( Corrado, ML, 1991)
"G6PD deficiency is very frequent with almost 400 millions of patients worldwide in Asia, Africa and Mediterranean."1.35[Ofloxacin is contraindicated in case of G6PD deficiency: is it evidenced based?]. ( Algayres, JP; Bonnefoy, S; Bordier, L; Callot, D; Carmoi, T; Lecoules, S, 2009)
"Levofloxacin 500 mg was given to 24 of the 85 patients who underwent simultaneous hysterectomy by intravenous injection since 1 day after the operation once a day and then given orally once a day for 4-8 days when the condition was improved."1.35[Prevention of peri-operative infection with levofloxacin in female patients undergoing surgery for stress urinary incontinence]. ( Cao, DY; Wang, JH; Zhang, Y; Zhu, L, 2008)
"Bacterial prostatitis is documented at a very low prevalence (7-13% of prostatitis overall considered) due to either reduced utilization of viral and bacteriological tests (Meares test, urethral swab, bacterial and viral PCR) or to the possibility that individual patients show a scarce expression of bacterial disease in biological fluids, because of intraglandular biofilm presence, with subsequent spreading of the sole plankton microrganisms."1.35[Chronic prostatitis and biofilm]. ( Bartoletti, R; Cai, T, 2009)
"aeruginosa from respiratory tract infections at 13-21%, which was the same trend as in past years."1.35[In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,919 clinical isolates obtained from 72 centers in 2007]. ( Aihara, M; Akiyama, T; Akizawa, K; Aoki, Y; Asano, Y; Baba, H; fujimoto, Y; Fujita, J; Fujita, S; Fujiwara, H; Genma, H; Gonda, H; Haruki, K; Hashikita, G; Hayashi, M; Heijyou, H; Hida, Y; Hiramatsu, K; Horiuchi, H; Ichiyama, S; Idomuki, M; Ieiri, T; Ikeda, N; Inuzuka, K; Iriyama, J; Ishii, Y; Ito, T; Iwata, M; Kaku, M; Kamioka, M; Kanda, M; Kang, D; Kanno, H; Katayama, Y; Kato, J; Kawahara, K; Kawamura, C; Kawano, S; Kawashima, C; Kinoshita, S; Kobayashi, Y; Kohno, S; Koike, K; Kon, S; Kondou, S; Kono, H; Kumasaka, K; Kusaba, K; Kusakabe, T; Kusano, N; Kuwabara, M; Maekawa, M; Maesaki, S; Masaki, H; Mashiba, K; Matsuda, J; Matsuda, K; Matsuo, S; Miki, M; Misawa, S; Miyajima, E; Miyanohara, H; Moro, K; Murakami, M; Murase, M; Murata, M; Nagai, A; Nakagawa, T; Nakamura, K; Nakashima, Y; Nakasone, I; Nakatani, K; Nakaya, H; Negayama, K; Ohno, A; Oka, M; Okabe, H; Okada, M; Okamoto, H; Okamoto, Y; Okayama, A; Okazaki, T; Okubo, S; Ono, J; Ota, H; Ozaki, Y; Saikawa, T; Saito, T; Sano, R; Sekine, I; Shigeta, M; Shimizu, C; Shiotani, J; Soma, M; Sugita, A; Sugiura, T; Sumitomo, M; Suwabe, A; Takubo, T; Taniguchi, N; Tashiro, H; Tateda, K; Tazawa, Y; Tominaga, M; Toyoshima, S; Uchida, T; Yamaguchi, I; Yamaguchi, K; Yamahata, K; Yamamoto, G; Yamamoto, Y; Yamane, N; Yamashita, M; Yamazaki, K; Yanagihara, K; Yasujima, M; Yoneyama, A; Yoshida, H; Yoshimura, H; Yuzuki, Y, 2009)
" By the antibacterial activity and bioavailability sodium furasidin is advantages among the nitrofurans."1.33[Results of the study on antibiotic resistance emergence among pathogens of community-acquired urinary tract infections in Moscow. Phase I]. ( Ivanov, DV; Sidorenko, SV, 2005)
" pneumoniae, MPC results were below susceptible breakpoints and within clinically achievable and sustainable drug concentrations for >24 hours of the dosing interval against."1.33Comparison of the minimum inhibitory, mutant prevention and minimum bactericidal concentrations of ciprofloxacin, levofloxacin and garenoxacin against enteric Gram-negative urinary tract infection pathogens. ( Blondeau, JM; Hansen, GT, 2005)
"Polymorphic ventricular tachycardia (PVT) is a form of ventricular tachycardia characterized by QRS complexes that seem to change direction during the tachycardia."1.31Levofloxacin induced polymorphic ventricular tachycardia with normal QT interval. ( Mousavi, MS; O'Donoghue, S; Paltoo, B, 2001)
"Ten patients with clinical symptoms of benign prostatic hyperplasia undergoing TUR-P received 200 mg of both drugs per os simultaneously 2 hours before surgery."1.31Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate. ( Chen, J; Chen, RR; Huang, HS, 2001)
"Ofloxacin serum levels were analyzed once prior to, on day 6 during and on day 3 after drug administration."1.30The influence of ofloxacin (Tarivid) on the parasite-host inter-relationship in patients with chronic urinary tract infection. ( Fünfstück, R; Gerth, J; Schubert, K; Stein, G; Straube, E; Wolfram, M, 1999)
"Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12."1.28[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992)
"Ofloxacin was determined to have the widest spectrum of activity and potential empiric use (90."1.28Ofloxacin, a new broad-spectrum fluoroquinolone. Results from a Multicenter, National Comparative Activity Surveillance Study. The Ofloxacin Surveillance Group. ( Erwin, ME; Jones, RN; Reller, LB; Rosati, LA; Sanchez, ML, 1992)
"Against respiratory tract infections with K."1.28In vivo evaluation of NM441, a new thiazeto-quinoline derivative. ( Kimura, K; Kise, M; Kitano, M; Matsuda, M; Nishino, T; Otsuki, M; Ozaki, M; Segawa, J; Shibata, K; Tomii, Y, 1991)
"Ofloxacin can cause retarded ossification and arthropathy in young animals, but there is no published information about its teratogenicity in humans."1.28Ofloxacin during the second trimester of pregnancy. ( Friedman, S; Hod, M; Merlob, P; Peled, Y, 1991)
"Ofloxacin was administered to 26 males infected with Ureaplasma urealyticum."1.28Effect of ofloxacin in the treatment of genitourinary tract infection with Ureaplasma urealyticum. ( Hoshino, H; Kawamura, N; Koinuma, A; Nakajima, N; Tanaka, M, 1989)
"Ofloxacin (Tarivid) is a 4-quinolone of the latest generation."1.27[Assessment of the genotoxic risk caused by the gyrase inhibitor ofloxacin using sister chromatid exchange rate analysis]. ( Brugger, P; Klein, G; Kullich, W, 1988)
"Ofloxacin (OFLX) was administered at a dose of 200 mg, three times daily (600 mg) for 14 days, to 15 patients suffering from complicated urinary tract infection."1.27[Clinical study of ofloxacin in complicated urinary tract infection]. ( Akazawa, N; Asahi, T; Hayata, S; Okita, K; Sasaki, H; Tsugawa, M, 1988)
"Ciprofloxacin was the most active agent."1.27In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species. ( Allocati, N; Cellini, L; Di Girolamo, A; Piccolomini, R; Scazzocchio, F; Selan, L, 1988)
"Treatment with ofloxacin in 15 patients with chronic renal failure at different stages is reported with respect to patients undergoing hemodialysis treatment."1.27[Ofloxacin treatment in nephrologic problem patients with various degrees of chronic renal failure (including dialysis treatment). Preliminary results]. ( Dörfler, A; Schulz, W, 1986)
"Ofloxacin was active against all but one (Pseudomonas aeruginosa) blood culture isolates."1.27Comparative activity of ofloxacin with reference to bacterial strains isolated in in-patients and out-patients. ( Alkan, M; Berger, S; Bogokowski, B; Keren, G; Mark, Z; Rubinstein, E, 1986)

Research

Studies (235)

TimeframeStudies, this research(%)All Research%
pre-199057 (24.26)18.7374
1990's66 (28.09)18.2507
2000's87 (37.02)29.6817
2010's21 (8.94)24.3611
2020's4 (1.70)2.80

Authors

AuthorsStudies
Higashide, M1
Kuroda, M1
Omura, CT1
Kumano, M1
Ohkawa, S1
Ichimura, S1
Ohta, T1
Blango, MG1
Mulvey, MA1
Prasada Rao, CMM1
Vennila, T1
Kosanam, S1
Ponsudha, P1
Suriyakrishnaan, K1
Alarfaj, AA1
Hirad, AH1
Sundaram, SR1
Surendhar, PA1
Selvam, N1
Lecuru, M1
Daniau, C1
Alfandari, S1
Dumartin, C1
Bajolet, O1
Blanchard, H1
Simon, L1
Colomb-Cotinat, M1
Lafaurie, M1
Chevret, S1
Fontaine, JP1
Mongiat-Artus, P1
de Lastours, V1
Escaut, L1
Jaureguiberry, S1
Bernard, L1
Bruyere, F1
Gatey, C1
Abgrall, S1
Ferreyra, M1
Aumaitre, H1
Aparicio, C1
Garrait, V1
Meyssonnier, V1
Bourgarit-Durand, A1
Chabrol, A1
Piet, E1
Talarmin, JP1
Morrier, M1
Canoui, E1
Charlier, C1
Etienne, M1
Pacanowski, J1
Grall, N1
Desseaux, K1
Empana-Barat, F1
Madeleine, I1
Bercot, B1
Molina, JM1
Lefort, A1
Axford, SB1
Andersen, CC1
Stark, MJ1
Ouni, B1
Fathallah, N1
Slim, R1
Brahim, A1
Ben Salem, C1
Páez-Canro, C1
Alzate, JP1
González, LM1
Rubio-Romero, JA1
Lethaby, A1
Gaitán, HG1
Rice, DA1
Kaniga, K3
Lee, M1
Redman, R4
Goyal, T1
Varshney, A1
Sharma, V1
Zawar, V1
Mumoli, N1
Cei, M1
Carmoi, T1
Bordier, L1
Bonnefoy, S1
Callot, D1
Lecoules, S1
Algayres, JP1
Johnson, L1
Sabel, A1
Burman, WJ1
Everhart, RM1
Rome, M1
MacKenzie, TD1
Rozwadowski, J1
Mehler, PS1
Price, CS1
Cao, DY1
Zhu, L1
Wang, JH1
Zhang, Y1
Lajiness, MJ1
Wagenlehner, FM2
Wagenlehner, C2
Weidner, W1
Naber, KG11
Koul, S1
Bhan-Kotwal, S1
Jenkins, HS1
Carmaciu, CD1
Llorens, L1
Kotey, P2
Hedrich, D1
Lin, JN1
Lai, CH1
Chen, YH1
Huang, CK1
Lin, HF1
Eng, HL1
Lin, HH1
Bartoletti, R1
Cai, T1
Zhang, YY1
Huang, HH1
Ren, ZY1
Zheng, HG1
Yu, YS1
Lü, XJ1
Xiao, ZK1
Yang, HF1
Xiu, QY1
Chen, BY1
Yue, HM1
Hao, QL1
Huang, JA1
Ma, H1
Xiao, W1
Guo, DY1
Si, B1
Sun, SH1
Zhang, W1
Li, QH1
Shen, HH1
Duan, J1
Li, HY1
Yao, WZ1
Gu, JM1
Xia, QM1
Ying, KJ1
Liu, A1
Yang, HP1
Shi, MH1
Sun, TY1
Ding, GH1
Wu, GM1
Yamaguchi, K2
Ohno, A1
Ishii, Y1
Tateda, K1
Iwata, M2
Kanda, M2
Akizawa, K1
Shimizu, C1
Kon, S1
Nakamura, K1
Matsuda, K1
Tominaga, M1
Nakagawa, T1
Sugita, A1
Ito, T1
Kato, J1
Suwabe, A1
Yamahata, K1
Kawamura, C2
Tashiro, H2
Horiuchi, H2
Katayama, Y1
Kondou, S1
Misawa, S1
Murata, M1
Kobayashi, Y1
Okamoto, H1
Yamazaki, K1
Okada, M1
Haruki, K1
Kanno, H1
Aihara, M1
Maesaki, S1
Hashikita, G1
Miyajima, E1
Sumitomo, M1
Saito, T1
Yamane, N2
Kawashima, C1
Akiyama, T2
Ieiri, T1
Yamamoto, Y1
Okamoto, Y1
Okabe, H1
Moro, K1
Shigeta, M1
Yoshida, H2
Yamashita, M1
Hida, Y1
Takubo, T1
Kusakabe, T1
Masaki, H1
Heijyou, H1
Nakaya, H1
Kawahara, K1
Sano, R1
Matsuo, S1
Kono, H1
Yuzuki, Y1
Ikeda, N1
Idomuki, M1
Soma, M1
Yamamoto, G1
Kinoshita, S2
Kawano, S1
Oka, M1
Kusano, N1
Kang, D1
Ono, J2
Yasujima, M2
Miki, M1
Hayashi, M1
Okubo, S1
Toyoshima, S2
Kaku, M2
Sekine, I1
Shiotani, J1
Tazawa, Y2
Yoneyama, A1
Kumasaka, K1
Koike, K1
Taniguchi, N1
Ozaki, Y1
Uchida, T1
Murakami, M1
Inuzuka, K1
Gonda, H1
Yamaguchi, I1
fujimoto, Y1
Iriyama, J1
Asano, Y1
Genma, H1
Maekawa, M1
Yoshimura, H1
Nakatani, K1
Baba, H1
Ichiyama, S1
Fujita, S1
Kuwabara, M2
Okazaki, T1
Fujiwara, H1
Ota, H1
Nagai, A1
Fujita, J1
Negayama, K2
Sugiura, T1
Kamioka, M1
Murase, M1
Nakasone, I2
Okayama, A1
Aoki, Y1
Kusaba, K1
Nakashima, Y1
Miyanohara, H1
Hiramatsu, K1
Saikawa, T1
Yanagihara, K1
Matsuda, J1
Kohno, S1
Mashiba, K1
Deguchi, T3
Nakane, K1
Yasuda, M3
Shimizu, T1
Monden, K1
Arakawa, S5
Matsumoto, T5
Drago, L3
Nicola, L2
Mattina, R1
De Vecchi, E2
Mirone, V1
Bush, LM1
Kaye, D1
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Schaeffer, AJ1
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Yamada, Y1
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Ramalakshmi, S1
Bastacky, S1
Johnson, JP1
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Shikano, M1
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Masuda, H1
Kawakami, S1
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Kihara, K1
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Thyroff-Friesinger, U2
Liassine, N1
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Rahal, K1
Morita, M2
Ito, S1
Suzuki, K4
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Cole, TP1
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Fennig, S1
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Horiba, M1
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Nicolle, LE1
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Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Non-Inferiority Study for Shortening Tuberculosis Treatment With Sitafloxacin-Containing Regimens[NCT05454345]Phase 3620 participants (Anticipated)Interventional2022-10-01Not yet recruiting
A Multicenter, Double-Blind, Randomized, Phase 3 Study of Doripenem Verus a Comparator Antibiotic in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis[NCT00229021]Phase 3741 participants (Actual)Interventional2003-12-31Completed
A Multicenter, Phase 3 Study of the Safety and Effectiveness of Doripenem in Complicated Lower Urinary Tract Infection or Pyelonephritis[NCT00210990]Phase 3403 participants (Actual)Interventional2004-03-31Completed
[NCT02729116]Phase 2/Phase 330 participants (Anticipated)Interventional2016-07-31Active, not recruiting
Antibiotic Prophylaxis for HDR Brachytherapy in the Treatment of Prostate Cancer: a Phase III Randomized Trial[NCT03862170]Phase 3255 participants (Anticipated)Interventional2015-02-10Suspended (stopped due to Covid-19 pandemic)
A Multicenter, Double-blind, Randomized Study to Compare the Efficacy and Safety of Levofloxacin 750 mg Once Daily for Five Days Versus Ciprofloxacin Twice Daily for Ten Days in the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis[NCT00210886]Phase 31,109 participants (Actual)Interventional2004-10-31Completed
Controlling Antimicrobial Use Through Reducing Unnecessary Treatment of Catheter Associated Urinary Tract Infections (CARCUTI)[NCT02650518]Phase 2/Phase 3500 participants (Anticipated)Interventional2015-12-31Recruiting
Antibiotic Prophylaxis for Transrectal Prostate Biopsy-Ciprofloxacin vs. Trimethoprim/Sulfamethoxazole[NCT02734732]Phase 22,800 participants (Anticipated)Interventional2015-04-30Recruiting
Does Prophylaxis With Macrobid Reduce the Incidence of Urinary Tract Infection in Patients Who Receive a Sub-Urethral Sling for the Treatment of Stress Urinary Incontinence: Randomized, Double Blinded Placebo Controlled Clinical Trial[NCT00734968]Phase 4161 participants (Actual)Interventional2008-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Post-operative UTI Following the Placement of Sub-urethral Sling for the Treatment of Stress Urinary Incontinence

The overall rate of UTI following the placement of sub-urethral sling for the treatment of stress urinary incontinence in our study was 24.8% (n = 37) (NCT00734968)
Timeframe: 6 weeks

Interventionparticipants (Number)
Treatment13
Placebo24

Incidence of Post-operative UTI in Placebo Group

The incidence of UTI in the placebo group was 32%. (NCT00734968)
Timeframe: 6 weeks

Interventionparticipants (Number)
Treatment13
Placebo24

Incidence of Post-operative UTI in Treatment Group

The incidence of UTI in the nitrofurantoin group was 17.6%. (NCT00734968)
Timeframe: 6 weeks

Interventionparticipants (Number)
Treatment13
Placebo24

Reviews

23 reviews available for ofloxacin and Urinary Tract Infections

ArticleYear
Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non-pregnant women.
    The Cochrane database of systematic reviews, 2019, Jan-25, Volume: 1

    Topics: Anti-Bacterial Agents; Asymptomatic Infections; Azithromycin; Chlamydia Infections; Chlamydia tracho

2019
[From cystitis to bacterial prostatitis: experience with levofloxacin].
    Le infezioni in medicina, 2009, Volume: 17 Suppl 5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cystitis; Double-Blind Method; Drug Therapy, Combinatio

2009
The expanding role of fluoroquinolones.
    The American journal of medicine, 2002, Jul-08, Volume: 113 Suppl 1A

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Ga

2002
Renal parenchymal malacoplakia: a rare cause of ARF with a review of recent literature.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:6

    Topics: Acute Kidney Injury; Aged; Biopsy, Needle; Cefuroxime; Diagnosis, Differential; Drug Therapy, Combin

2003
Levofloxacin in the treatment of urinary tract infections and prostatitis.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 2

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug

2004
[Levofloxacin (Tavanic) and therapy of urogenital infections].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2004, Volume: 49, Issue:6

    Topics: Animals; Female; Humans; Levofloxacin; Male; Ofloxacin; Urinary Tract Infections

2004
[Levofloxacin and other antibacterial drugs].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2006, Volume: 51, Issue:6

    Topics: Anti-Bacterial Agents; Bacterial Infections; Dermatitis; Dosage Forms; Humans; Levofloxacin; Ofloxac

2006
Usefulness and problems of the urinary tract infection criteria for evaluating drug efficacy for complicated urinary tract infections.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2007, Volume: 13, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amdinocillin Pivoxil; Anti-Infective Agents, Urinary; Cephalosporins

2007
Fluoroquinolones reviewed.
    Drug and therapeutics bulletin, 1993, Aug-31, Volume: 31, Issue:18

    Topics: Adult; Anti-Infective Agents; Child; Ciprofloxacin; Clinical Trials as Topic; Female; Humans; Norflo

1993
[Ten-year experience with the use of ofloxacin (Tarivid*). New treatment regimens].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:9

    Topics: Anti-Infective Agents; Drug Administration Schedule; Humans; Ofloxacin; Respiratory Tract Infections

1996
Levofloxacin and sparfloxacin: new quinolone antibiotics.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3

    Topics: Absorption; Anti-Infective Agents; Bronchitis; Drug Interactions; Drug Resistance, Microbial; Fluoro

1998
Levofloxacin. Its use in infections of the respiratory tract, skin, soft tissues and urinary tract.
    Drugs, 1998, Volume: 56, Issue:3

    Topics: Animals; Anti-Infective Agents; Humans; Levofloxacin; Ofloxacin; Respiratory Tract Infections; Skin

1998
Ofloxacin. A reappraisal of its use in the management of genitourinary tract infections.
    Drugs, 1998, Volume: 56, Issue:5

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Drug Resistance; Female

1998
[Levofloxacin for prevalent infections in primary care medicine].
    Enfermedades infecciosas y microbiologia clinica, 1999, Volume: 17 Suppl 1

    Topics: Anti-Infective Agents; Bacterial Infections; Community-Acquired Infections; Humans; Levofloxacin; Of

1999
New uses for new and old quinolones and the challenge of resistance.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2

    Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Humans; M

2000
The fluoroquinolones after ciprofloxacin and ofloxacin.
    Current clinical topics in infectious diseases, 2000, Volume: 20

    Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Naphthyridines; Ofloxacin; Pi

2000
A risk-benefit assessment of levofloxacin in respiratory, skin and skin structure, and urinary tract infections.
    Drug safety, 2001, Volume: 24, Issue:3

    Topics: Animals; Anti-Infective Agents; Drug Resistance, Microbial; Drug-Related Side Effects and Adverse Re

2001
[The first 'respiration' fluoroquinolone--levofloxacin (Tavanic) in therapy of bacterial infections. Pharmacodynamics principles in optimization of administration regimens].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2001, Volume: 46, Issue:7

    Topics: Acute Disease; Animals; Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infec

2001
[Role of levofloxacin in the treatment of urinary tract infections].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2001, Volume: 73, Issue:2

    Topics: Anti-Infective Agents, Urinary; Female; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Urinary

2001
[Use of levofloxacin in the antibiotic prophylaxis for diagnostic procedures in urology].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2002, Volume: 74, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinar

2002
Worldwide clinical experience with ofloxacin in urologic cases.
    Urology, 1991, Volume: 37, Issue:3 Suppl

    Topics: Female; Global Health; Humans; Male; Ofloxacin; Urinary Tract Infections

1991
The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans.
    Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:5

    Topics: Anti-Bacterial Agents; Bacteria; Blood Proteins; Ciprofloxacin; Enoxacin; Fluorine; Humans; Kidney;

1985
The role of 4-quinolones in the treatment of infections.
    Comprehensive therapy, 1987, Volume: 13, Issue:2

    Topics: Bacterial Infections; Ciprofloxacin; Humans; Kinetics; Norfloxacin; Ofloxacin; Oxazines; Urinary Tra

1987

Trials

74 trials available for ofloxacin and Urinary Tract Infections

ArticleYear
Antimicrobial for 7 or 14 Days for Febrile Urinary Tract Infection in Men: A Multicenter Noninferiority Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 06-16, Volume: 76, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Double-Blind Method; Fever; Humans; Male; Ofloxacin; U

2023
Activity of doripenem versus comparators in subjects with baseline bacteraemia in six pooled phase 3 clinical trials.
    International journal of antimicrobial agents, 2013, Volume: 41, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Carbapenems; Cross Infection; Doripenem; Female; Humans; Imipenem

2013
Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Carbapenems; Doripenem; Double-Blin

2009
Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Carbapenems; Doripenem; Double-Blind Method; Fema

2009
Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2009, Volume: 15, Issue:5

    Topics: Administration, Oral; Adolescent; Aged; Anti-Bacterial Agents; China; Dizziness; Drug Administration

2009
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Antibiotic prophylaxis in catheter-associated urinary infections.
    The new microbiologica, 2012, Volume: 35, Issue:2

    Topics: Antibiotic Prophylaxis; Female; Humans; Levofloxacin; Male; Ofloxacin; Urinary Catheterization; Urin

2012
Prulifloxacin versus levofloxacin in the treatment of respiratory and urinary tract infections: a multicentre, double-blind, randomized controlled clinical trial.
    Chemotherapy, 2012, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dioxolanes; Disk Diffusion Antimicrobial Tests; Doub

2012
Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk.
    The Journal of urology, 2002, Volume: 168, Issue:3

    Topics: Administration, Oral; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Biopsy, Needle; Humans

2002
[Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2002, Volume: 76, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; b

2002
[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2003, Volume: 75, Issue:1

    Topics: Anti-Infective Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Enterobacteriaceae

2003
Perioperative antibiotic prophylaxis in ureteroscopic stone removal.
    European urology, 2003, Volume: 44, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antibiotic Prophylaxis; Dose-Response Relationship, D

2003
Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate.
    European urology, 2005, Volume: 47, Issue:4

    Topics: Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Bacteriuria; Dr

2005
[Clinical significance of antibiotic prophylaxis for transrectal prostate biopsy].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2001, Volume: 39, Issue:12

    Topics: Aged; Aged, 80 and over; Antibiotic Prophylaxis; Biopsy, Needle; Ciprofloxacin; Drug Therapy, Combin

2001
A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis;

2006
Early discharge of hospitalised patients with community-acquired urosepsis when treated with levofloxacin in sequential therapy.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2006, Volume: 78, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Community-Acquired Infections; Drug Administr

2006
Usefulness and problems of the urinary tract infection criteria for evaluating drug efficacy for complicated urinary tract infections.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2007, Volume: 13, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amdinocillin Pivoxil; Anti-Infective Agents, Urinary; Cephalosporins

2007
Identification and pretherapy susceptibility of pathogens in patients with complicated urinary tract infection or acute pyelonephritis enrolled in a clinical study in the United States from November 2004 through April 2006.
    Clinical therapeutics, 2007, Volume: 29, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Ciprof

2007
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method].
    Hinyokika kiyo. Acta urologica Japonica, 1984, Volume: 30, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Clinical Trials as T

1984
[Clinical study on antimicrobial prophylaxis following extracorporeal shock wave lithotripsy].
    Hinyokika kiyo. Acta urologica Japonica, 1995, Volume: 41, Issue:4

    Topics: Adult; Bacteriuria; Cephalosporins; Female; Humans; Lithotripsy; Male; Middle Aged; Ofloxacin; Preme

1995
Application of NONMEM method for evaluation of relative biological availability of ofloxacin.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:1

    Topics: Adult; Biological Availability; Female; Humans; Male; Middle Aged; Nonlinear Dynamics; Ofloxacin; Re

1994
Double-blind study comparing 3-day regimens of cefixime and ofloxacin in treatment of uncomplicated urinary tract infections in women.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Cefixime; Cefotaxime; Double-Blin

1994
Effective postcoital quinolone prophylaxis of recurrent urinary tract infections in women.
    The Journal of urology, 1994, Volume: 152, Issue:1

    Topics: Adult; Ciprofloxacin; Coitus; Female; Humans; Norfloxacin; Ofloxacin; Prospective Studies; Recurrenc

1994
[Clinical study of Chinese ofloxacin].
    Zhonghua yi xue za zhi, 1993, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Aged; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxacin; Respiratory Tract

1993
Single dose quinolone treatment in acute uncomplicated urinary tract infection in women.
    The Journal of urology, 1993, Volume: 149, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Ciprofloxacin; Female; Gram-Negative Bacterial Infect

1993
Fleroxacin versus ofloxacin in patients with complicated urinary tract infection: a controlled clinical study.
    The American journal of medicine, 1993, Mar-22, Volume: 94, Issue:3A

    Topics: Adult; Aged; Aged, 80 and over; Female; Fleroxacin; Humans; Male; Middle Aged; Ofloxacin; Prospectiv

1993
Pharmacokinetics of ofloxacin--measurement of drug concentration in saliva of patients with impaired renal function.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Anti-Infective Agents; Female; Humans; Kidney Diseases; Male; Middle Aged; Ofloxacin; Saliva; Urinar

1995
Evaluation of clinical efficacy of antimicrobials in complicated urinary tract infections. Comparison of Japanese criteria with IDSA guidelines. Infectious Diseases Society of America.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacteriuria; Female; Gram-Negative Bacteria;

1995
A randomised controlled trial of ofloxacin 200 mg 4 times daily or twice daily vs ciprofloxacin 500 mg twice daily in elderly nursing home patients with complicated UTI.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Aged; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Female; Humans; Male; Nursing H

1995
Single dose UTI prophylaxis in transurethral surgery. Oral ofloxacin vs parenteral cefotaxime.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Cefotaxime; Cephalosp

1995
3-day course of ofloxacin versus cefalexin in the treatment of urinary tract infections in postmenopausal women.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:9

    Topics: Aged; Anti-Infective Agents, Urinary; Cephalexin; Cephalosporins; Costs and Cost Analysis; Female; H

1996
[Clinical experience with the use of ofloxacin in infections of the upper and lower urinary tracts: demonstrations of the results of clinical trials].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:9

    Topics: Anti-Infective Agents, Urinary; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema

1996
Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials.
    JAMA, 1998, Jan-14, Volume: 279, Issue:2

    Topics: Adult; Anti-Infective Agents; Area Under Curve; Bacterial Infections; Bayes Theorem; Dose-Response R

1998
A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection.
    Urology, 1998, Volume: 51, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Female; Fluor

1998
Treatment of community-acquired acute uncomplicated urinary tract infection with sparfloxacin versus ofloxacin. The Sparfloxacin Multi Center UUTI Study Group.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Community-Acquired Infections; Female; Fluo

1998
Efficacy of one dose fluoroquinolone before prostate biopsy.
    Urology, 1998, Volume: 52, Issue:4

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Biopsy, Needle; Costs and Cost Analysis; Follow-Up St

1998
[Efficacy of lomefloxacin in treatment of nonspecific inflammatory diseases and in prophylaxis of postoperative complications in urology].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Female; F

1998
A randomized trial of short-course ciprofloxacin, ofloxacin, or trimethoprim/sulfamethoxazole for the treatment of acute urinary tract infection in women. Ciprofloxacin Urinary Tract Infection Group.
    The American journal of medicine, 1999, Volume: 106, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary

1999
Antibiotic prophylaxis for transrectal biopsy of the prostate: a prospective randomized study of the prophylactic use of single dose oral fluoroquinolone versus trimethoprim-sulfamethoxazole.
    International urology and nephrology, 1999, Volume: 31, Issue:4

    Topics: Administration, Oral; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotic Prophy

1999
Quinolones for short-term treatment of uncomplicated urinary tract infection.
    East African medical journal, 1999, Volume: 76, Issue:10

    Topics: 4-Quinolones; Administration, Oral; Adult; Anti-Infective Agents; Bacterial Infections; Female; Fluo

1999
Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury.
    International journal of antimicrobial agents, 2000, Volume: 13, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Biofilms; Double-Blin

2000
Ciprofloxacin 250 mg twice daily versus ofloxacin 200 mg twice daily in the treatment of complicated urinary tract infections in women.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2000, Volume: 19, Issue:5

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Double-Blind Method; Drug Administ

2000
An open, non comparative study of ofloxacin i.v. on the treatment of acute symptomatic urinary tract infection.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2000, Volume: 83, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Dose-Response Relationship, Drug; Drug

2000
Oral fluoroquinolone therapy results in drug adsorption on ureteral stents and prevention of biofilm formation.
    International journal of antimicrobial agents, 2001, Volume: 17, Issue:4

    Topics: Administration, Oral; Adsorption; Anti-Infective Agents; Anti-Infective Agents, Urinary; Biofilms; C

2001
Patient-initiated treatment of uncomplicated recurrent urinary tract infections in young women.
    Annals of internal medicine, 2001, Jul-03, Volume: 135, Issue:1

    Topics: Adult; Algorithms; Anti-Infective Agents, Urinary; Feasibility Studies; Female; Follow-Up Studies; H

2001
Randomized, double-blind, comparative study of levofloxacin and ofloxacin in the treatment of complicated urinary tract infections.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 1999, Volume: 32, Issue:1

    Topics: Adult; Aged; Anti-Infective Agents; Bacteria; Double-Blind Method; Female; Humans; Levofloxacin; Mal

1999
[Tavanik effectiveness and safety in the treatment of urinary tract infection complications].
    Klinicheskaia meditsina, 2001, Volume: 79, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Male; Middle Aged; Of

2001
Spectrum and susceptibility of pathogens causing acute uncomplicated lower UTI in females and its correlation to bacteriologic outcome after single dose therapy with fosfomycin trometamol versus ofloxacin/co-trimoxazole.
    Infection, 1992, Volume: 20 Suppl 4

    Topics: Acute Disease; Adolescent; Adult; Aged; Drug Administration Schedule; Female; Fosfomycin; Humans; Mi

1992
Ofloxacin versus trimethoprim and co-trimoxazole in the treatment of uncomplicated urinary tract infection in general practice.
    The British journal of clinical practice, 1992,Spring, Volume: 46, Issue:1

    Topics: Adult; Aged; Escherichia coli Infections; Family Practice; Female; Humans; Male; Middle Aged; Ofloxa

1992
[Study of the long-term administration of ofloxacin to the patients following transurethral resection of the prostate].
    Hinyokika kiyo. Acta urologica Japonica, 1991, Volume: 37, Issue:1

    Topics: Aged; Drug Administration Schedule; Drug Evaluation; Humans; Male; Middle Aged; Ofloxacin; Postopera

1991
Randomized study to evaluate efficacy and safety of ofloxacin vs. trimethoprim and sulfamethoxazole in treatment of uncomplicated urinary tract infection.
    Urology, 1991, Volume: 37, Issue:3 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Ofloxacin; Superinfection; Trimet

1991
Ofloxacin use in a geriatric population.
    Chemotherapy, 1991, Volume: 37 Suppl 1

    Topics: Aged; Cross Infection; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Ofloxacin; Pneumonia;

1991
Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside.
    Chemotherapy, 1991, Volume: 37 Suppl 1

    Topics: Administration, Oral; Adolescent; Aged; Bacteriuria; Drug Therapy, Combination; Gentamicins; Humans;

1991
Ofloxacin in urinary tract infections.
    Scandinavian journal of infectious diseases. Supplementum, 1990, Volume: 68

    Topics: Administration, Oral; Drug Administration Schedule; Half-Life; Humans; Ofloxacin; Time Factors; Urin

1990
[Clinical evaluation of ofloxacin in the treatment of chronic complicated urinary tract infection].
    Hinyokika kiyo. Acta urologica Japonica, 1990, Volume: 36, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Humans; M

1990
Fosfomycin trometamol versus ofloxacin/co-trimoxazole as single dose therapy of acute uncomplicated urinary tract infection in females: a multicentre study.
    Infection, 1990, Volume: 18 Suppl 2

    Topics: Adolescent; Adult; Aged; Bacteriuria; Drug Administration Schedule; Drug Therapy, Combination; Drug

1990
Severe infections treated with intravenous ofloxacin: a prospective clinical multicentre Swiss study.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl D

    Topics: Adolescent; Adult; Aged; Female; Gastrointestinal Diseases; Humans; Injections, Intravenous; Male; M

1990
Efficacy of intravenous ofloxacin: a French multicentre trial in 185 patients.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl D

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Female; Fran

1990
Comparison of i.v. ofloxacin and piperacillin in the treatment of complicated urinary tract infections.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl D

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gram-Negative Bacteria; Humans; Injections, Intr

1990
[Single-dose amoxicillin, TMP-SMX and ofloxacin therapy in lower urinary tract infections].
    Mikrobiyoloji bulteni, 1989, Volume: 23, Issue:3

    Topics: Adult; Amoxicillin; Female; Humans; Middle Aged; Ofloxacin; Trimethoprim, Sulfamethoxazole Drug Comb

1989
[Use of ofloxacin in 45 cases of infection of the lower urinary tract in women].
    Minerva ginecologica, 1989, Volume: 41, Issue:11

    Topics: Adult; Drug Administration Schedule; Drug Evaluation; Female; Humans; Middle Aged; Ofloxacin; Urinar

1989
Ofloxacin in the management of complicated urinary tract infections, including prostatitis.
    The American journal of medicine, 1989, Dec-29, Volume: 87, Issue:6C

    Topics: Administration, Oral; Adult; Aged; Bacterial Infections; Carbenicillin; Drug Resistance, Microbial;

1989
[Clinical trial of ofloxacin (Tarivid R)].
    Vutreshni bolesti, 1988, Volume: 27, Issue:3

    Topics: Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Hum

1988
Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxa

1986
Ofloxacin compared with ciprofloxacin in the treatment of complicated lower urinary tract infections.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22 Suppl C

    Topics: Ciprofloxacin; Double-Blind Method; Humans; Ofloxacin; Prospective Studies; Random Allocation; Urina

1988
Failure of a single dose of 100 mg ofloxacin in lower urinary tract infections in females.
    Scandinavian journal of infectious diseases, 1987, Volume: 19, Issue:6

    Topics: Anti-Infective Agents, Urinary; Clinical Trials as Topic; Drug Combinations; Escherichia coli Infect

1987
Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections.
    Drugs, 1987, Volume: 34 Suppl 1

    Topics: Adult; Anti-Infective Agents; Bacteriuria; Female; Humans; Male; Microbial Sensitivity Tests; Norflo

1987
Ofloxacin vs. cotrimoxazole in patients with complicated urinary tract infections.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Drug Combinations; Female; Humans; Male; Middle Aged; O

1987
[Summarized results of clinical phase II and III studies with ofloxacin (HOE 280) in Europe].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Anti-Infective Agents; Bacterial Infections; Clinical Trials as Topic; Drug Evaluation; Drug Resista

1986
[Ofloxacin versus pipemidic acid and co-trimoxazole].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Adult; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dos

1986
A multicenter study on clinical efficacy of ofloxacin in respiratory and urinary tract infections.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adult; Aged; Anti-Infective Agents; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Ofl

1986
Clinical experience with ofloxacin in urinary tract infection.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Anti-Infective Agents; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Ofloxacin;

1986
Clinical evaluation of ofloxacin versus ciprofloxacin in complicated urinary tract infections.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Anti-Infective Agents; Ciprofloxacin; Clinical Trials as Topic; Double-Blind Method; Female; Humans;

1986

Other Studies

139 other studies available for ofloxacin and Urinary Tract Infections

ArticleYear
Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Bacterial Proteins; Chromosomes, Bacterial; Electrophoresis, Gel, Pulsed-Field; Methicillin Resistan

2008
Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Cell Membrane Permeability; Cells, Cultured; Drug Resistan

2010
Assessment of Bacterial Isolates from the Urine Specimens of Urinary Tract Infected Patient.
    BioMed research international, 2022, Volume: 2022

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli

2022
Evolution of antibiotic treatments for healthcare-associated infections caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae in France.
    Infectious diseases now, 2022, Volume: 52, Issue:7

    Topics: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Cla

2022
Standardised antenatal antibiotic regimens and neonatal sepsis-Are we certain we have it right?
    The Australian & New Zealand journal of obstetrics & gynaecology, 2020, Volume: 60, Issue:2

    Topics: Anti-Bacterial Agents; Female; Humans; Neonatal Sepsis; Ofloxacin; Pregnancy; Quinolones; Urinary Tr

2020
Anaphylactic shock secondary to oral ofloxacin administration with cross-reactivity to levofloxacin and ciprofloxacin.
    Therapie, 2018, Volume: 73, Issue:6

    Topics: Administration, Oral; Adolescent; Anaphylaxis; Ciprofloxacin; Cross Reactions; Drug Hypersensitivity

2018
A rare case of facial annular bullous erythema nodosum leprosum reaction in a young boy.
    International journal of dermatology, 2016, Volume: 55, Issue:6

    Topics: Adolescent; Anti-Infective Agents, Urinary; Drug Eruptions; Erythema Nodosum; Humans; Leprosy, Lepro

2016
A case of purple urine.
    QJM : monthly journal of the Association of Physicians, 2009, Volume: 102, Issue:2

    Topics: Aged, 80 and over; Anti-Infective Agents, Urinary; Dehydration; Female; Humans; Hypernatremia; Oflox

2009
[Ofloxacin is contraindicated in case of G6PD deficiency: is it evidenced based?].
    La Revue de medecine interne, 2009, Volume: 30, Issue:4

    Topics: Contraindications; Diabetes Complications; Escherichia coli Infections; Female; Glucosephosphate Deh

2009
Emergence of fluoroquinolone resistance in outpatient urinary Escherichia coli isolates.
    The American journal of medicine, 2008, Volume: 121, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Drug Resist

2008
[Prevention of peri-operative infection with levofloxacin in female patients undergoing surgery for stress urinary incontinence].
    Zhonghua yi xue za zhi, 2008, Jun-03, Volume: 88, Issue:21

    Topics: Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Drug Administration Schedule; F

2008
Common antibiotics for the treatment of urinary tract infections.
    Urologic nursing, 2008, Volume: 28, Issue:5

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Costs; Humans; Nitrofurantoin; Nurse's Role; Ofloxacin; P

2008
Organic psychosis induced by ofloxacin and metronidazole.
    British journal of hospital medicine (London, England : 2005), 2009, Volume: 70, Issue:4

    Topics: Adolescent; Anti-Infective Agents; Antipsychotic Agents; Citalopram; Drug Therapy, Combination; Fema

2009
Urinary Mycobacterium szulgai infection in an immunocompetent patient.
    Southern medical journal, 2009, Volume: 102, Issue:9

    Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Immunocompetence; Isoniazid; Levof

2009
[Chronic prostatitis and biofilm].
    Le infezioni in medicina, 2009, Volume: 17 Suppl 1

    Topics: Adult; Biofilms; Chronic Disease; Ciprofloxacin; Contraception Behavior; Diet; Disease Susceptibilit

2009
[In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,919 clinical isolates obtained from 72 centers in 2007].
    The Japanese journal of antibiotics, 2009, Volume: 62, Issue:4

    Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; G

2009
Microbiological outcome of complicated urinary tract infections treated with levofloxacin: a pharmacokinetic/pharmacodynamic analysis.
    International journal of antimicrobial agents, 2010, Volume: 35, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Computer Simulation; Female; H

2010
In vitro selection of resistance in Escherichia coli and Klebsiella spp. at in vivo fluoroquinolone concentrations.
    BMC microbiology, 2010, Apr-21, Volume: 10

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Ciprofloxacin; Dioxolanes; DNA Gyrase; DNA Mutational Ana

2010
Catheter-associated urinary tract infection IDSA guidelines: why the levofloxacin?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Aug-15, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Catheter-Related Infections; Humans; Levofloxacin; Of

2010
Risk factors and mechanisms of fluoroquinolone resistance in 156 Escherichia coli strains clinically isolated from urinary tract infections.
    Scandinavian journal of infectious diseases, 2011, Volume: 43, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, B

2011
High rates of quinolone resistance among urinary tract infections in the ED.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents

2012
Ofloxacin: new applications for the prevention of urinary tract infections in renal graft recipients.
    Transplant infectious disease : an official journal of the Transplantation Society, 2011, Volume: 13, Issue:4

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Dru

2011
Evaluation by Monte Carlo simulation of levofloxacin dosing for complicated urinary tract infections caused by Escherichia coli or Pseudomonas aeruginosa.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2011, Volume: 17, Issue:5

    Topics: Anti-Bacterial Agents; Area Under Curve; Computer Simulation; Databases, Factual; Escherichia coli;

2011
Consensus statement on the role of fluoroquinolones in the management of urinary tract infections.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2011, Volume: 44, Issue:2

    Topics: Anti-Bacterial Agents; Consensus Development Conferences as Topic; Drug Resistance, Bacterial; Esche

2011
Mechanisms of and risk factors for fluoroquinolone resistance in clinical Enterococcus faecalis isolates from patients with urinary tract infections.
    Journal of clinical microbiology, 2011, Volume: 49, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resist

2011
Relationship between urinary tract infection categorization and pathogens' antimicrobial susceptibilities.
    Urologia internationalis, 2012, Volume: 88, Issue:2

    Topics: Anti-Infective Agents; Catheter-Related Infections; Ceftazidime; Enterococcus faecalis; Escherichia

2012
Comparative in vitro activity of sitafloxacin against bacteria isolated from Thai patients with urinary tract infections and lower respiratory tract infections.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95 Suppl 2

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Levofloxaci

2012
Acute renal failure caused by severe coagulopathy induced by the interaction between warfarin potassium and levofloxacin: a case report.
    Journal of anesthesia, 2012, Volume: 26, Issue:6

    Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Anticoagulants; Blood Coagulation Disorders; Card

2012
Four consecutive cases of Achilles tendon disorders associated with levofloxacin treatment in hemodialysis patients.
    Clinical and experimental nephrology, 2012, Volume: 16, Issue:6

    Topics: Achilles Tendon; Administration, Oral; Aged; Anti-Infective Agents, Urinary; Dose-Response Relations

2012
Bacteriological conversion in twenty urinary tuberculosis patients treated with ofloxacin, rifampin and isoniazid: a 10-year follow-up study.
    International microbiology : the official journal of the Spanish Society for Microbiology, 2002, Volume: 5, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antitubercular Agents; Drug Therapy, Combination; Femal

2002
Erythema multiforme-like rash in a patient sensitive to ofloxacin.
    Acta dermato-venereologica, 2002, Volume: 82, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Conjunctivitis, Bacterial; Drug Hypersensitivity; Drug Therapy, Comb

2002
Levofloxacin-induced granulomatous interstitial nephritis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:2

    Topics: Female; Granuloma; Humans; Levofloxacin; Middle Aged; Nephritis, Interstitial; Ofloxacin; Urinary Tr

2003
[Antibacterial activity of gatifloxacin against various fresh clinical isolates in 2002].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cefdinir; Cephalosporins; Ciprof

2002
[Comparative in vitro bacteriostatic and bactericidal activity of levofloxacin and ciprofloxacin against urinary tract pathogens determined by MIC, MBC, Time-Kill curves and bactericidal index analysis].
    Le infezioni in medicina, 2002, Volume: 10, Issue:2

    Topics: Anti-Infective Agents; Ciprofloxacin; Gram-Negative Bacteria; Humans; Levofloxacin; Microbial Sensit

2002
Pyocystis in patients on chronic dialysis. A potentially misdiagnosed syndrome.
    International urology and nephrology, 2002, Volume: 34, Issue:3

    Topics: Aged; Anti-Infective Agents; Diagnostic Errors; Diverticulitis; Female; Humans; Kidney Failure, Chro

2002
[Cefepime (maxipime) in the treatment of severe urinary tract infection].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:7

    Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; D

2003
Longer than recommended empiric antibiotic treatment of urinary tract infection in women: an avoidable waste of money.
    Journal of clinical pharmacy and therapeutics, 2004, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Drug Administration Schedule; Drug Costs; D

2004
Physician adherence to recommendations for duration of empiric antibiotic treatment for uncomplicated urinary tract infection in women: a national drug utilization analysis.
    Pharmacoepidemiology and drug safety, 2004, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Drug Utilization; Female; Humans; Middle Aged; Nitrofurantoin; Ofloxacin; T

2004
Urinary tract infection caused by Aerococcus viridans, a case report.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:11

    Topics: Aged; Aged, 80 and over; Bacteremia; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male;

2004
[Evaluation of levofloxacin susceptibility against strains isolated from lower urinary tract infections in the community].
    Pathologie-biologie, 2005, Volume: 53, Issue:2

    Topics: Anti-Infective Agents, Urinary; Bacterial Infections; Community-Acquired Infections; Escherichia col

2005
Evolution of fluoroquinolone resistance among Escherichia coli urinary tract isolates from a French university hospital: application of the dynamic regression model.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:4

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli

2005
[Uroinfections and the possibilities of therapy with levofloxacin].
    Khirurgiia, 2004, Volume: 60, Issue:4-5

    Topics: Anti-Infective Agents, Urinary; Drug Administration Schedule; Genital Diseases, Male; Humans; Levofl

2004
[Results of the study on antibiotic resistance emergence among pathogens of community-acquired urinary tract infections in Moscow. Phase I].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2005, Volume: 50, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacterial Infections; Ce

2005
In vitro activity of lomefloxacin, a new difluorinated quinolone, against urinary bacterial isolates: comparison with enoxacin and ofloxacin.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Anti-Infective Agents; Bacteria; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Of

1989
In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Humans; Microbial Sensitivity Tes

1989
Ofloxacin in the treatment of genito-urinary tract infections.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Female Urogenital Disea

1989
Experience with ofloxacin for short and long-term treatment of urinary tract infections in renal transplant recipients.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Follow-Up Studies; Humans; Kidney Transplantation; Ofloxacin; Postoperative Complications; Recurrenc

1989
Comparison of the minimum inhibitory, mutant prevention and minimum bactericidal concentrations of ciprofloxacin, levofloxacin and garenoxacin against enteric Gram-negative urinary tract infection pathogens.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteri

2005
A puzzling case of high serum creatinine in a healthy woman.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Creatinine; Drug Administration Schedule; False Positive Reactions; Fe

2006
Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event?
    Southern medical journal, 2006, Volume: 99, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Electrocardiography; F

2006
Clinical efficacy and tolerability of levofloxacin in patients with liver disease: a prospective, non comparative, observational study.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:1

    Topics: Administration, Oral; Anti-Bacterial Agents; Chronic Disease; Drug Tolerance; Female; Humans; Levofl

2006
A Rare but serious side effect of Levofloxacin: hypoglycemia in a geriatric patient.
    Diabetes care, 2006, Volume: 29, Issue:7

    Topics: Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemia; Levofloxacin; Middle Aged; Ofloxacin; Pneum

2006
Continuous versus intermittent levofloxacin treatment in complicated urinary tract infections caused by urinary obstruction temporarily relieved by foreign body insertion.
    International journal of antimicrobial agents, 2006, Volume: 28 Suppl 1

    Topics: Anti-Infective Agents, Urinary; Biofilms; Drug Administration Schedule; Female; Foreign Bodies; Huma

2006
Prevalence and natural history of colonization with fluoroquinolone-resistant gram-negative bacilli in community-dwelling people with spinal cord dysfunction.
    Archives of physical medicine and rehabilitation, 2006, Volume: 87, Issue:10

    Topics: Anti-Bacterial Agents; Carrier State; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial;

2006
Levofloxacin-induced interstitial nephritis and vasculitis in an elderly woman.
    The Israel Medical Association journal : IMAJ, 2006, Volume: 8, Issue:10

    Topics: Acute Kidney Injury; Aged, 80 and over; Anti-Bacterial Agents; Fatal Outcome; Female; Humans; Levofl

2006
In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance.
    International journal of antimicrobial agents, 2007, Volume: 29, Issue:6

    Topics: Anti-Infective Agents, Urinary; Bacterial Adhesion; Ciprofloxacin; Dioxolanes; Drug Resistance, Bact

2007
[In vitro activity of prulifloxacin, levofloxacin and ciprofloxacin against urinary pathogens].
    Le infezioni in medicina, 2006, Volume: 14, Issue:1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Dioxolanes; Drug Resistance, Multiple, Bacterial; Fluoroquinol

2006
[A case of urinary tract infection caused by Flavimonas oryzihabitans].
    Mikrobiyoloji bulteni, 2007, Volume: 41, Issue:1

    Topics: Anti-Infective Agents, Urinary; Bacteriuria; Carbapenems; Drug Resistance, Multiple, Bacterial; Fema

2007
[Drug-resistant bacteria isolated from pharyngeal swab cultures and urine in acutely or chronically febrile elderly nursing home inmates].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2007, Volume: 44, Issue:3

    Topics: Acute Disease; Aged; Chronic Disease; Drug Resistance, Bacterial; Escherichia coli; Fever; Fluoroqui

2007
Multidrug-induced erythema multiforme.
    Journal of investigational allergology & clinical immunology, 2007, Volume: 17, Issue:3

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Ceftriaxone; Ci

2007
Tissue reactions of suture materials (polyglactine 910, chromed catgut and polydioxanone) on rat bladder wall and their role in bladder stone formation.
    Urological research, 2008, Volume: 36, Issue:1

    Topics: Animals; Anti-Infective Agents, Urinary; Catgut; Cystitis; Female; Foreign-Body Reaction; Mucous Mem

2008
Acute bacterial prostatitis after transrectal prostate needle biopsy: clinical analysis.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2008, Volume: 14, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Biopsy, Needle; Blood; Carbapenems; Cephalosporins; Drug Resistance, Ba

2008
Demonstration of persistence of Salmonella typhimurium in an AIDS patient by molecular methods.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Bacteriophage Typing; Bacteriuria; Diarrhea; DNA Trans

1994
Lack of increase in resistance to quinolones in general practice isolates of Escherichia coli.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:1

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Clavulanic Acids;

1994
North American (United States and Canada) comparative susceptibility of two fluoroquinolones: ofloxacin and ciprofloxacin. A 53-medical-center sample of spectra of activity. North American Ofloxacin Study Group.
    Diagnostic microbiology and infectious disease, 1994, Volume: 18, Issue:1

    Topics: Bacteria; Bacterial Infections; Canada; Ciprofloxacin; Enterobacteriaceae; Female; Genitalia; Humans

1994
Single dose of ofloxacin treatment in women with dysuria and frequency.
    International urology and nephrology, 1993, Volume: 25, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Drug Resistance, Micr

1993
Criteria for use of ofloxacin and lomefloxacin in adult inpatients and outpatients.
    Clinical pharmacy, 1993, Volume: 12, Issue:6

    Topics: Adult; Anti-Infective Agents; Fluoroquinolones; Gram-Negative Bacterial Infections; Humans; Infectio

1993
In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:3

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Lung Diseases

1993
[Ecology of pathogenic bacteria in the infected urine].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1996, Volume: 70, Issue:7

    Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Drug Resistance, Microbial; Escherichia co

1996
Therapeutic effects of cefozopran against experimental mixed urinary tract infection with Enterococcus faecalis and Pseudomonas aeruginosa in mice.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:3

    Topics: Ampicillin; Animals; Cefozopran; Ceftazidime; Cephalosporins; Cilastatin; Enterococcus faecalis; Fem

1997
Development of a rapid assay for detecting gyrA mutations in Escherichia coli and determination of incidence of gyrA mutations in clinical strains isolated from patients with complicated urinary tract infections.
    Journal of clinical microbiology, 1997, Volume: 35, Issue:9

    Topics: Anti-Infective Agents; Asparagine; Ciprofloxacin; DNA Gyrase; DNA Topoisomerases, Type II; DNA, Bact

1997
Neuropsychiatric complications following quinolone overdose in renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Confusion; Drug Over

1999
The influence of ofloxacin (Tarivid) on the parasite-host inter-relationship in patients with chronic urinary tract infection.
    International journal of antimicrobial agents, 1999, Volume: 11, Issue:3-4

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Adhesion; Colony Count, Microbial; Female; Hu

1999
National guideline for the management of prostatitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
    Sexually transmitted infections, 1999, Volume: 75 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, U

1999
Shiga toxin-producing Escherichia coli urinary tract infection associated with hemolytic-uremic syndrome in an adult and possible adverse effect of ofloxacin therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Escherichia coli Infections; Escherichia coli O157; Fem

2000
[Activities of antimicrobial agents against 5,180 clinical isolates obtained from 26 medical institutions during 1998 in Japan. Levofloxacin--Surveillance Group].
    The Japanese journal of antibiotics, 2000, Volume: 53, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Ba

2000
In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections.
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:3

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gatifloxaci

2000
Effect of Mao-bushi-saishin-to on infection of ofloxacin resistant bacteria and of unknown origin.
    Complementary therapies in medicine, 2000, Volume: 8, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents; Bacterial Infections; Body

2000
[Pharma-clinics. The drug of the month. Levofloxacin (Tavanic)].
    Revue medicale de Liege, 2000, Volume: 55, Issue:11

    Topics: Acute Disease; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Bronchit

2000
Seasonal variation in fluoroquinolone prescribing.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:2

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Utilization Review; England; Humans; Norfloxacin; Ofloxac

1999
Levofloxacin induced polymorphic ventricular tachycardia with normal QT interval.
    Pacing and clinical electrophysiology : PACE, 2001, Volume: 24, Issue:5

    Topics: Anti-Infective Agents, Urinary; Electrocardiography; Female; Humans; Levofloxacin; Middle Aged; Oflo

2001
Activity of levofloxacin and ciprofloxacin against urinary pathogens.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:1

    Topics: Anti-Infective Agents; Bacterial Adhesion; Ciprofloxacin; Drug Resistance, Microbial; Escherichia co

2001
The impact of norfloxacin, ciprofloxacin and ofloxacin on human gut colonization by Candida albicans.
    Scandinavian journal of infectious diseases, 2001, Volume: 33, Issue:6

    Topics: Adult; Aged; Anti-Infective Agents; Candida albicans; Ciprofloxacin; Digestive System; Female; Human

2001
Patient-initiated treatment of recurrent urinary tract infection in women.
    Annals of internal medicine, 2001, Jul-03, Volume: 135, Issue:1

    Topics: Adult; Anti-Infective Agents, Urinary; Female; Follow-Up Studies; Humans; Middle Aged; Ofloxacin; Pa

2001
Acute fatal hepatitis related to levofloxacin.
    Journal of hepatology, 2001, Volume: 35, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chemical and Drug In

2001
Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2001, Volume: 100, Issue:8

    Topics: Aged; Anti-Infective Agents; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Postoperative Compli

2001
[Antibiotics in urinary tract infections. One quinolone for 3 days].
    MMW Fortschritte der Medizin, 2001, Oct-04, Volume: 143, Issue:40

    Topics: Anti-Infective Agents, Urinary; Clinical Trials as Topic; Drug Administration Schedule; Humans; Oflo

2001
Spectrum and activity of three contemporary fluoroquinolones tested against Pseudomonas aeruginosa isolates from urinary tract infections in the SENTRY Antimicrobial Surveillance Program (Europe and the Americas; 2000): more alike than different!
    Diagnostic microbiology and infectious disease, 2001, Volume: 41, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cipro

2001
[Efficacy of a single-day administration of levofloxacin for the prevention of urinary tract infections after urogenital examinations and treatments for outpatients].
    Hinyokika kiyo. Acta urologica Japonica, 2001, Volume: 47, Issue:11

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents, Urinar

2001
Effect of subminimal inhibitory concentrations of three fluoroquinolones on adherence of uropathogenic strains of Escherichia coli.
    International journal of antimicrobial agents, 2002, Volume: 19, Issue:1

    Topics: Anti-Infective Agents; Bacterial Adhesion; Cell Line; Ciprofloxacin; Escherichia coli; Escherichia c

2002
[Profile and sensitivity to antibiotics of 2063 uropathogenic bacteria isolated in the center of Tunisia].
    Bulletin de la Societe de pathologie exotique (1990), 2002, Volume: 95, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Colistin; Escherichia coli; Female;

2002
[Resistance to new quinolones among the enterobacteria].
    Archives de l'Institut Pasteur d'Algerie. Institut Pasteur d'Algerie, 1992, Volume: 58

    Topics: Drug Resistance, Microbial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Nalidixic Aci

1992
[Clinical evaluation of oral ofloxacin in 3-day therapy for transurethral resection of the prostate].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:7

    Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Administration Schedule; Humans; Male; Middle Ag

1992
The dipstick test in the diagnosis of UTI and the effect of pretreatment catheter exchange in catheter-associated UTI.
    Infection, 1992, Volume: 20 Suppl 3

    Topics: Bacteriuria; Esterases; Evaluation Studies as Topic; Humans; Japan; Leukocyte Count; Levofloxacin; N

1992
Ofloxacin-induced delirium.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:4

    Topics: Delirium; Female; Hospitalization; Humans; Middle Aged; Ofloxacin; Psychoses, Substance-Induced; Uri

1992
[Ofloxacin: a new ally in the treatment of urinary infections and bacterial prostatitis].
    Archivos espanoles de urologia, 1992, Volume: 45, Issue:2

    Topics: Bacterial Infections; Humans; Male; Ofloxacin; Prostatitis; Urinary Tract Infections

1992
[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:6

    Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Epididymitis; Escherichia coli; Humans;

1992
Ofloxacin, a new broad-spectrum fluoroquinolone. Results from a Multicenter, National Comparative Activity Surveillance Study. The Ofloxacin Surveillance Group.
    Diagnostic microbiology and infectious disease, 1992, Volume: 15, Issue:5

    Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Microbial; Enterobacteriaceae; Haemophilus influen

1992
In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:12

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dogs; Drug Evaluati

1991
Ofloxacin during the second trimester of pregnancy.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:11

    Topics: Adult; Cartilage, Articular; Female; Fetus; Gestational Age; Humans; Infant, Newborn; Maternal-Fetal

1991
[In vitro sensitivity of gram-negative bacteria isolated from urinary tract infections to various antibiotics].
    Mikrobiyoloji bulteni, 1991, Volume: 25, Issue:1

    Topics: Amikacin; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftazi

1991
Effects of ofloxacin on cell-mediated immune response and lymphokine production.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:5

    Topics: Analysis of Variance; Humans; Immunity, Cellular; Interferon Type I; Interferon-gamma; Interleukin-2

1990
[Pefloxacin in the treatment of recurrent urinary tract infections].
    Casopis lekaru ceskych, 1990, Jul-27, Volume: 129, Issue:30

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Ofloxacin; Pefloxacin; Recurrence; Urinary Tract Inf

1990
[In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Aged; Anti-Infective Agents, Urinary; Bacteria; Cross Infection; Dose-Response Relationship, Drug; F

1986
[An epidemiologic study of the antibiotic susceptibility of bacteria isolated from patients with urinary tract infections].
    Mikrobiyoloji bulteni, 1989, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Bacteria; Cefotaxime; Escherichia coli; Escheric

1989
Effect of ofloxacin in the treatment of genitourinary tract infection with Ureaplasma urealyticum.
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:12

    Topics: Adult; Humans; Male; Mycoplasmatales Infections; Ofloxacin; Ureaplasma; Urinary Tract Infections

1989
Clinical role of the quinolones today and in the future.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:12

    Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Clinical Protocols; Forecasting; Humans;

1989
In vivo activity of ciprofloxacin, ofloxacin, norfloxacin and pipemidic acid against Escherichia coli infections in mice.
    Drugs under experimental and clinical research, 1989, Volume: 15, Issue:2

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli Infections; Female; Mice; Microbial

1989
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:8

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquino

1989
[Assessment of the genotoxic risk caused by the gyrase inhibitor ofloxacin using sister chromatid exchange rate analysis].
    Wiener medizinische Wochenschrift (1946), 1988, Mar-15, Volume: 138, Issue:5

    Topics: Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Ofloxacin; Oxazines; Sister Chr

1988
Clinical use of the quinolones.
    Lancet (London, England), 1987, Dec-05, Volume: 2, Issue:8571

    Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthy

1987
In vitro and in vivo antibacterial activity of AM-833, a new quinolone derivative.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Micr

1986
[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity].
    Pathologie-biologie, 1988, Volume: 36, Issue:5

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance,

1988
In vitro susceptibility of urinary pathogens to quinolones compared to other antimicrobial agents.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Anti-Bacterial Agents; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Norfloxacin; Ofloxac

1987
[Clinical reevaluation of ofloxacin (OFLX) in urinary tract infections].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Humans; Middle Aged; Ofloxacin; Oxazines; Urinary T

1988
[Treatment of complicated urinary tract infections by ofloxacin].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Male; Middle Aged; Ofloxacin;

1988
[Therapy of complicated urinary tract infections using ofloxacin--a 2d generation antibacterial quinolone].
    Casopis lekaru ceskych, 1988, May-06, Volume: 127, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Female; Humans; Male; Middle Aged; O

1988
[Personal experience with ofloxacin in patients with resistant urinary tract infections].
    Vnitrni lekarstvi, 1988, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Drug Resistance, Microbial; Female;

1988
[Clinical study of ofloxacin in complicated urinary tract infection].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:7

    Topics: Administration, Oral; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Ofloxacin; Urinary Tract I

1988
Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:5

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Experimental; Female; Fluoroquinol

1988
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:5

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Microbial Sensitivity Tests; Nalid

1988
Serum and prostatic tissue concentrations of ofloxacin.
    Clinical therapeutics, 1988, Volume: 10 Spec No

    Topics: Administration, Oral; Aged; Aged, 80 and over; Half-Life; Humans; Male; Middle Aged; Ofloxacin; Post

1988
Single low-dose ofloxacin for the treatment of uncomplicated urinary tract infection in young women.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Contraceptive Devices, Female; Contraceptives, Oral; Female; Humans; Middle Aged;

1988
[The in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections].
    Mikrobiyoloji bulteni, 1988, Volume: 22, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Ofloxa

1988
In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; beta-Lactamases; Enterobacteriaceae; Half-Life; Humans;

1988
[Ofloxacin (RU 43280). Clinical study].
    Pathologie-biologie, 1987, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Therapy, Combination; Enterobacteriaceae Infect

1987
[The role of ofloxacin (Tarivid) therapy in respiratory and urinary tract infections].
    Mikrobiyoloji bulteni, 1987, Volume: 21, Issue:3

    Topics: Acute Disease; Chronic Disease; Escherichia coli; Humans; Klebsiella; Ofloxacin; Proteus; Pseudomona

1987
[Ofloxacin treatment in nephrologic problem patients with various degrees of chronic renal failure (including dialysis treatment). Preliminary results].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Adult; Aged; Aluminum Hydroxide; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infections; Cre

1986
Ofloxacin: clinical evaluation in urinary and respiratory infections.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adult; Aged; Anti-Infective Agents; Female; Humans; Male; Middle Aged; Ofloxacin; Oxazines; Pneumoni

1986
Ofloxacin therapy of difficult-to-treat infections due to multiresistant organisms.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacteriuria; Drug Re

1987
[Clinical study of ofloxacin (OFLX) on urinary tract infections].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacteria;

1987
[Clinical evaluation of ofloxacin against complicated urinary tract infections].
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:9

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacteria; Drug

1987
Application of ofloxacin in gynaecology.
    Drugs, 1987, Volume: 34 Suppl 1

    Topics: Anti-Bacterial Agents; Female; Genital Diseases, Female; Humans; Lactobacillus; Microbial Sensitivit

1987
Bacteriological and clinical experiences with ofloxacin in urinary tract infections.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Humans; Ofloxacin; Urinary Tract Infect

1987
Comparative activity of ofloxacin with reference to bacterial strains isolated in in-patients and out-patients.
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cross Infection; Dose-Response Relationship,

1986
[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections].
    Pathologie-biologie, 1986, Volume: 34, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cystitis; Female; Humans; Male; Middle Age

1986
The in-vitro activity of EN 272, a quinolone-7-carboxylic acid, in comparison with other quinolones.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naph

1985
[Anti-bacterial effect of ofloxacin--in vitro and in vivo results].
    Mikrobiyoloji bulteni, 1985, Volume: 19, Issue:4

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Enterobacteriaceae; Humans; Microbial Sensiti

1985
[The study of urinary tract infection with a possible cause of fungi and evaluation of the efficacy of 5-FC].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:10

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Candida albicans; Candidiasis; Cyto

1985