ofloxacin has been researched along with Typhoid Fever in 67 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Typhoid Fever: An acute systemic febrile infection caused by SALMONELLA TYPHI, a serotype of SALMONELLA ENTERICA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adults and children clinically diagnosed with uncomplicated enteric fever were enrolled in the study to receive gatifloxacin (10 mg/kg/day) in a single dose or ofloxacin (20 mg/kg/day) in two divided doses for 7 days." | 9.17 | Gatifloxacin versus ofloxacin for the treatment of uncomplicated enteric fever in Nepal: an open-label, randomized, controlled trial. ( Agrawal, K; Arjyal, A; Baker, S; Basnyat, B; Campbell, J; Dolecek, C; Dongol, S; Farrar, J; Giri, A; Karkey, A; Koirala, KD; Koirala, S; Pathak, KR; Shakya, M; Shilpakar, O; Shrestha, K; Shrestha, R; Shrestha, UM; Thapa, SD; Wolbers, M, 2013) |
| "This intervention study was conducted to determine the efficacy of Levofloxacin in the treatment of uncomplicated enteric fever." | 9.15 | Effectiveness of levofloxacin in enteric fever. ( Ahmed, MA; Ali, MH; Haque, MA; Islam, MA; Rokonuzzaman, SM; Uddin, MN, 2011) |
| "The main objective of this study was to determine the clinical efficacy and safety of levofloxacin in an open setting for typhoid fever cases." | 9.12 | Open study on efficacy and safety of levofloxacin in treatment of uncomplicated typhoid fever. ( Chen, K; Nelwan, RH; Paramita, D, 2006) |
| "We conducted a randomized open trial of oral chloramphenicol (50mg/kg/day in four divided doses for 14 days) versus ofloxacin (15 mg/kg/day in two divided doses for 3 days) in 50 adults with culture-confirmed uncomplicated typhoid fever in Vientiane, Laos." | 9.11 | A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos. ( Blacksell, SD; Darasavath, C; Mayxay, M; Newton, PN; Phetsouvanh, R; Phongmany, S; Ramsay, AC; Rattanavong, O; Sisouphone, S; Syhavong, B; Thammavong, C; Vongphachane, P; White, NJ, 2005) |
| "In a double blind randomized study, 80 Vietnamese children with uncomplicated typhoid fever were randomized to receive identical syrup preparations of ibuprofen (10 mg/kg) or paracetamol (12 mg/kg) every 6 h until 36 h after defervescence." | 9.11 | Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever. ( Chinh, MT; Day, NP; Diep, TS; Farrar, JJ; Hanh, VT; House, D; Parry, CM; Tham, CT; Thao, NT; Vinh, H; Wain, J; White, NJ, 2004) |
| "An open, randomised comparison of 2 or 3 days of oral ofloxacin (10 mg/kg/day) for uncomplicated typhoid fever was conducted in 235 Vietnamese children." | 9.11 | Comparative trial of short-course ofloxacin for uncomplicated typhoid fever in Vietnamese children. ( Bay, PV; Day, NP; Diep, TS; Duong, NM; Ho, VA; Parry, CM; Phuong, le T; Truong, NT; Vinh, H; Wain, J; White, NJ, 2005) |
| ", resistant to chloramphenicol, ampicillin, and cotrimoxazole) and nalidixic acid-resistant enteric fever, azithromycin (1 g once daily for 5 days at 20 mg/kg/day) and ofloxacin (200 mg orally twice a day for 5 days at 8 mg/kg/day) were compared in an open randomized study in adults admitted to a hospital with uncomplicated enteric fever." | 9.09 | A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. ( Chinh, NT; Diep, TS; Farrar, JJ; Ha, HD; Ly, NT; Parry, CM; Thong, MX; Wain, J; White, NJ, 2000) |
| "Cefixime, an orally administered third generation cephalosporin, was compared with ofloxacin for the treatment of uncomplicated typhoid fever in children." | 9.09 | A comparative study of ofloxacin and cefixime for treatment of typhoid fever in children. The Dong Nai Pediatric Center Typhoid Study Group. ( Cao, XT; Kneen, R; Nguyen, TA; Parry, CM; Truong, DL; White, NJ, 1999) |
| "An open randomized comparison of 2 days (Ofx2) versus 3 days (Ofx3) of oral ofloxacin treatment (15 mg/kg/day) was conducted with Vietnamese children between 1 and 15 years of age with suspected typhoid fever." | 9.08 | Two or three days of ofloxacin treatment for uncomplicated multidrug-resistant typhoid fever in children. ( Bethell, D; Cao, NN; Mai, TC; Nguyen, MD; Nguyen, TT; Tu, SD; Vinh, H; Vo, TN; Wain, J; White, NJ, 1996) |
| "An open, randomized comparison of ofloxacin (200 mg, every 12 h) given orally for 5 days and ceftriaxone (3 g, once daily) given intravenously for 3 days in the treatment of uncomplicated enteric fever was conducted in Ho Chi Minh City, Vietnam." | 9.07 | Comparison of ofloxacin and ceftriaxone for short-course treatment of enteric fever. ( Day, NP; Diep, TS; Duong, NM; Ha, HD; Hien, TT; Hoa, NT; Smith, MD; Wain, J; White, NJ, 1994) |
| "Ofloxacin has been successfully used in the treatment of typhoid fever and Salmonella infectious of adults for many years." | 7.69 | Ofloxacin versus co-trimoxazole in the treatment of typhoid fever in children. ( Akan, O; Ceyhan, M; Ecevit, Z; Figen, G; Kanra, G; Seçmeer, G, 1997) |
| "Ofloxacin was used in the treatment of 20 cases of typhoid fever, 32 cases of bacillary dysentery and 50 cases of gonococcal infection." | 7.68 | [Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea]. ( Jiang, YF; Wang, QN; Zou, QY, 1991) |
| "In recent times there have been several reports of chloramphenicol resistant enteric fever necessitating the use of other antimicrobial agents." | 7.68 | Chloramphenicol resistant enteric fever. ( Chakravorty, B; Gupta, B; Jain, N; Krishna, A; Rajvanshi, P; Sen, MK, 1993) |
| "During 1984 to 1988, 35 patients with urinary tract infection (UTI) and 37 patients with enteric fever were treated successfully with 400 mg ofloxacin twice a day for 7 to 10 days." | 7.67 | In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever. ( Srimuang, S; Tanphaichitra, D, 1988) |
| "Nine patients with typhoid fever were given ofloxacin in a daily dosage of 400 mg for ten days." | 7.67 | [Treatment of typhoid fever using ofloxacin. Clinical experience and determination of antibiotic diffusion into the mesenteric lymph nodes]. ( Bru, JP; Croize, J; Fourtillan, JB; Le Noc, P; Leclercq, P; Lefebvre, MA; Micoud, M; Stahl, JP, 1986) |
| "Ofloxacin, 300 mg 12-hourly, was given orally to 64 patients with typhoid fever, all with positive blood cultures." | 7.67 | Treatment of typhoid fever with ofloxacin. ( Gu, XJ; Tai, TY; Wang, F; Zhang, MF, 1989) |
| "Uncomplicated typhoid fever due to isolates of MDR S." | 6.73 | Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever. ( Bay, PV; Farrar, JJ; Hien, TT; Ho, VA; Lanh, MN; Parry, CM; Phuong, le T; Tham, NT; Tung, le T; Wain, J, 2007) |
| " The mean (95% CI) oral bioavailability was 91% (74 to 109%)." | 6.68 | Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever. ( Bethell, DB; Day, NP; Dung, NM; Dung, NQ; Linh, NT; Loan, HT; MacGowan, AP; McMullin, C; Minh, LT; Tam, DT; Vinh, H; White, LO; White, NJ, 1996) |
| "Typhoid fever is an important cause of morbidity and mortality in patients especially in developing country." | 5.33 | Levofloxacin in enteric fever--a study. ( Baliga, V; Desai, A; Gawde, A; Kadam, GS; Naikwadi, A; Rao, SK; Sawardekar, SS, 2005) |
| "Recently we experienced two male typhoid patients who required additional treatment with CP sodium succinate (CP succinate) to OFLX therapy." | 5.28 | [Combination therapy with ofloxacin and chloramphenicol against typhoid fever]. ( Doi, H; Honda, S; Ichimura, H; Koda, T; Kurimura, O; Tamura, I, 1990) |
| "The antibiotic of choice for the treatment of typhoid fever in most parts of the world is still chloramphenicol." | 5.28 | Therapeutic implications of ofloxacin in the treatment of typhoid fever caused by multiply resistant Salmonella typhi. ( Ashfaq, MK; Farooqui, BJ; Ishaq, M; Khan, MA, 1990) |
| "Ofloxacin was well absorbed orally." | 5.28 | [Efficacy of ofloxacin in treating typhoid fever]. ( Gu, XJ; Wang, F; Zhang, MF, 1989) |
| "Adults and children clinically diagnosed with uncomplicated enteric fever were enrolled in the study to receive gatifloxacin (10 mg/kg/day) in a single dose or ofloxacin (20 mg/kg/day) in two divided doses for 7 days." | 5.17 | Gatifloxacin versus ofloxacin for the treatment of uncomplicated enteric fever in Nepal: an open-label, randomized, controlled trial. ( Agrawal, K; Arjyal, A; Baker, S; Basnyat, B; Campbell, J; Dolecek, C; Dongol, S; Farrar, J; Giri, A; Karkey, A; Koirala, KD; Koirala, S; Pathak, KR; Shakya, M; Shilpakar, O; Shrestha, K; Shrestha, R; Shrestha, UM; Thapa, SD; Wolbers, M, 2013) |
| "There is a clear relationship between ofloxacin susceptibility and clinical outcome in ofloxacin treated patients with enteric fever." | 5.15 | The influence of reduced susceptibility to fluoroquinolones in Salmonella enterica serovar Typhi on the clinical response to ofloxacin therapy. ( Baker, S; Campbell, JI; Chinh, NT; Farrar, JJ; Hien, TT; Parry, CM; Vinh, H; Wain, J, 2011) |
| "This intervention study was conducted to determine the efficacy of Levofloxacin in the treatment of uncomplicated enteric fever." | 5.15 | Effectiveness of levofloxacin in enteric fever. ( Ahmed, MA; Ali, MH; Haque, MA; Islam, MA; Rokonuzzaman, SM; Uddin, MN, 2011) |
| "To study the epidemiological pattern, clinical picture, the recent trends of multidrug-resistant typhoid fever (MDRTF), and therapeutic response of ofloxacin and ceftriaxone in MDRTF." | 5.12 | Multidrug-resistant typhoid fever. ( Gupta, N; Kumar, R, 2007) |
| "The main objective of this study was to determine the clinical efficacy and safety of levofloxacin in an open setting for typhoid fever cases." | 5.12 | Open study on efficacy and safety of levofloxacin in treatment of uncomplicated typhoid fever. ( Chen, K; Nelwan, RH; Paramita, D, 2006) |
| "We conducted a randomized open trial of oral chloramphenicol (50mg/kg/day in four divided doses for 14 days) versus ofloxacin (15 mg/kg/day in two divided doses for 3 days) in 50 adults with culture-confirmed uncomplicated typhoid fever in Vientiane, Laos." | 5.11 | A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos. ( Blacksell, SD; Darasavath, C; Mayxay, M; Newton, PN; Phetsouvanh, R; Phongmany, S; Ramsay, AC; Rattanavong, O; Sisouphone, S; Syhavong, B; Thammavong, C; Vongphachane, P; White, NJ, 2005) |
| "An open, randomised comparison of 2 or 3 days of oral ofloxacin (10 mg/kg/day) for uncomplicated typhoid fever was conducted in 235 Vietnamese children." | 5.11 | Comparative trial of short-course ofloxacin for uncomplicated typhoid fever in Vietnamese children. ( Bay, PV; Day, NP; Diep, TS; Duong, NM; Ho, VA; Parry, CM; Phuong, le T; Truong, NT; Vinh, H; Wain, J; White, NJ, 2005) |
| "In a double blind randomized study, 80 Vietnamese children with uncomplicated typhoid fever were randomized to receive identical syrup preparations of ibuprofen (10 mg/kg) or paracetamol (12 mg/kg) every 6 h until 36 h after defervescence." | 5.11 | Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever. ( Chinh, MT; Day, NP; Diep, TS; Farrar, JJ; Hanh, VT; House, D; Parry, CM; Tham, CT; Thao, NT; Vinh, H; Wain, J; White, NJ, 2004) |
| ", resistant to chloramphenicol, ampicillin, and cotrimoxazole) and nalidixic acid-resistant enteric fever, azithromycin (1 g once daily for 5 days at 20 mg/kg/day) and ofloxacin (200 mg orally twice a day for 5 days at 8 mg/kg/day) were compared in an open randomized study in adults admitted to a hospital with uncomplicated enteric fever." | 5.09 | A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. ( Chinh, NT; Diep, TS; Farrar, JJ; Ha, HD; Ly, NT; Parry, CM; Thong, MX; Wain, J; White, NJ, 2000) |
| "Cefixime, an orally administered third generation cephalosporin, was compared with ofloxacin for the treatment of uncomplicated typhoid fever in children." | 5.09 | A comparative study of ofloxacin and cefixime for treatment of typhoid fever in children. The Dong Nai Pediatric Center Typhoid Study Group. ( Cao, XT; Kneen, R; Nguyen, TA; Parry, CM; Truong, DL; White, NJ, 1999) |
| " In a paired, open, randomized study during an epidemic of multidrug-resistant typhoid in southern Vietnam, two short-course ofloxacin regimens (15 mg/kg daily for 3 days and 10 mg/kg daily for 5 days) were compared for the treatment of uncomplicated typhoid fever." | 5.08 | Short course of ofloxacin for treatment of multidrug-resistant typhoid. ( Bethell, DB; Bui, MC; Le, TP; Nguyen, MD; Nguyen, TT; Pham, TT; To, SD; Tran, TH; Wain, J; Walsh, AL, 1995) |
| "An open randomized comparison of 2 days (Ofx2) versus 3 days (Ofx3) of oral ofloxacin treatment (15 mg/kg/day) was conducted with Vietnamese children between 1 and 15 years of age with suspected typhoid fever." | 5.08 | Two or three days of ofloxacin treatment for uncomplicated multidrug-resistant typhoid fever in children. ( Bethell, D; Cao, NN; Mai, TC; Nguyen, MD; Nguyen, TT; Tu, SD; Vinh, H; Vo, TN; Wain, J; White, NJ, 1996) |
| "An open, randomized comparison of ofloxacin (200 mg, every 12 h) given orally for 5 days and ceftriaxone (3 g, once daily) given intravenously for 3 days in the treatment of uncomplicated enteric fever was conducted in Ho Chi Minh City, Vietnam." | 5.07 | Comparison of ofloxacin and ceftriaxone for short-course treatment of enteric fever. ( Day, NP; Diep, TS; Duong, NM; Ha, HD; Hien, TT; Hoa, NT; Smith, MD; Wain, J; White, NJ, 1994) |
| "Thirteen hospitalized patients with various infections, five with typhoid fever, two with gastroenteritis, four with respiratory tract infection and two with biliary tract infection, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally." | 5.06 | Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report. ( Altucci, P; Briante, V; Cristiano, P; Leonessa, V; Morelli, G; Paradisi, F, 1986) |
| "Recently, the cefixime-ofloxacin combination is approved by Drug Controller General of India to treat typhoid fever." | 3.85 | In vitro efficacy and in silico analysis of cefixime-ofloxacin combination for Salmonella Typhi from bloodstream infection. ( Babu, P; Bakthavatchalam, YD; Doss, CGP; Kumar, DT; Munusamy, E; Ravi, R; Shankar, BA; Tayubi, IA; Thukkaram, B; Veeraraghavan, B, 2017) |
| "Ofloxacin has been successfully used in the treatment of typhoid fever and Salmonella infectious of adults for many years." | 3.69 | Ofloxacin versus co-trimoxazole in the treatment of typhoid fever in children. ( Akan, O; Ceyhan, M; Ecevit, Z; Figen, G; Kanra, G; Seçmeer, G, 1997) |
| " He had noticed high fever since one month ago, and had been treated with prednisolone with the diagnosis of fever of unknown origin in a hospital." | 3.69 | [A case report--typhoid fever complicated with liver and gallbladder abscess, treated for long-time as fever of unknown origin]. ( Fukuda, J; Irimajiri, S; Kawashima, I; Matsuoka, Y; Obana, M; Suzuki, A; Suzuki, H; Suzuki, T, 1997) |
| "In the present study, 33 adult patients with salmonella infections consisting of 13 typhoid fever, 9 paratyphoid fever, 8 enterocolitis, 2 carriers, 1 acute gastroenteritis have been treated with ofloxacin." | 3.68 | [Ofloxacin treatment of salmonella infections]. ( Altay, G; Arman, D; Unlü, S, 1993) |
| "Ofloxacin was used in the treatment of 20 cases of typhoid fever, 32 cases of bacillary dysentery and 50 cases of gonococcal infection." | 3.68 | [Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea]. ( Jiang, YF; Wang, QN; Zou, QY, 1991) |
| "In recent times there have been several reports of chloramphenicol resistant enteric fever necessitating the use of other antimicrobial agents." | 3.68 | Chloramphenicol resistant enteric fever. ( Chakravorty, B; Gupta, B; Jain, N; Krishna, A; Rajvanshi, P; Sen, MK, 1993) |
| "Thirty-four hospitalized patients with various infections: 19 with typhoid fever, 4 with gastroenteritis, 7 with lower respiratory tract infections, 2 with biliary tract infections, 1 with brucellosis and 1 with infection of necrotic ulceration of the feet, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally." | 3.67 | Clinical experience with ofloxacin (DL-8280) in the therapy of various infections. ( Altucci, P; Cristiano, P; Iovene, MR; Mandia, L; Morelli, G; Paradisi, F, 1989) |
| "Ofloxacin, 300 mg 12-hourly, was given orally to 64 patients with typhoid fever, all with positive blood cultures." | 3.67 | Treatment of typhoid fever with ofloxacin. ( Gu, XJ; Tai, TY; Wang, F; Zhang, MF, 1989) |
| "During 1984 to 1988, 35 patients with urinary tract infection (UTI) and 37 patients with enteric fever were treated successfully with 400 mg ofloxacin twice a day for 7 to 10 days." | 3.67 | In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever. ( Srimuang, S; Tanphaichitra, D, 1988) |
| "We investigated the clinical efficiency and safety of ofloxacin, a new fluoroquinolone, for the treatment of various documented bacterial infections in 26 patients (10 females, 16 males) aged 17 to 84 years." | 3.67 | [Evaluation of the use of ofloxacin in the treatment of various infections]. ( Bertrand, JL; Lucht, F; Peyramond, D; Salord, F; Tigaud, S; Vedrinne, JM, 1986) |
| "Nine patients with typhoid fever were given ofloxacin in a daily dosage of 400 mg for ten days." | 3.67 | [Treatment of typhoid fever using ofloxacin. Clinical experience and determination of antibiotic diffusion into the mesenteric lymph nodes]. ( Bru, JP; Croize, J; Fourtillan, JB; Le Noc, P; Leclercq, P; Lefebvre, MA; Micoud, M; Stahl, JP, 1986) |
| "Cefixime can also be used for treatment of enteric fever but may not perform as well as fluoroquinolones." | 2.82 | Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins. ( Basnyat, B; Darton, TC; Eyre, D; Kuehn, R; Parry, CM; Stoesser, N, 2022) |
| "Uncomplicated typhoid fever due to isolates of MDR S." | 2.73 | Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever. ( Bay, PV; Farrar, JJ; Hien, TT; Ho, VA; Lanh, MN; Parry, CM; Phuong, le T; Tham, NT; Tung, le T; Wain, J, 2007) |
| " The mean (95% CI) oral bioavailability was 91% (74 to 109%)." | 2.68 | Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever. ( Bethell, DB; Day, NP; Dung, NM; Dung, NQ; Linh, NT; Loan, HT; MacGowan, AP; McMullin, C; Minh, LT; Tam, DT; Vinh, H; White, LO; White, NJ, 1996) |
| "Ofloxacin was also effective in the treatment of enteric fever, in which eradication was achieved in all seven patients." | 2.66 | Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections. ( Sahaphong, S; Srimuang, S; Tanphaichitra, D, 1986) |
| "We found serological evidence of acute murine typhus in 21 of 125 (17%) patients, with 12 of 21 (57%) patients polymerase chain reaction (PCR)-positive for Rickettsia typhi." | 1.42 | Undifferentiated febrile illness in Kathmandu, Nepal. ( Arjyal, A; Baker, S; Basnyat, B; Blacksell, SD; Day, N; Dolecek, C; Dongol, S; Farrar, J; Giri, A; Karkey, A; Paris, DH; Thompson, CN; Thwaites, G, 2015) |
| "Typhoid fever is an important cause of morbidity and mortality in patients especially in developing country." | 1.33 | Levofloxacin in enteric fever--a study. ( Baliga, V; Desai, A; Gawde, A; Kadam, GS; Naikwadi, A; Rao, SK; Sawardekar, SS, 2005) |
| "One hundred and seventy-eight cases of typhoid patients were studied on clinical and bacteriological aspects." | 1.30 | [Clinical and laboratory studies with typhoid fever 178 patients]. ( Ji, B; Lu, M; Ouyang, K, 1997) |
| "In this study, typhoid fever was diagnosed by isolation of Salmonella typhi from blood or by a positive Widal's reaction in 170 Pakistani children." | 1.29 | Multidrug-resistant Salmonella typhi in Pakistani children: clinical features and treatment. ( Bux, D; Hasan, M; Rathore, MH, 1996) |
| "typhi were effective against typhoid caused by ampicillin, chloramphenicol and sulfamethoxazole/trimethoprim-resistant strains." | 1.28 | Therapy of multidrug resistant typhoid in 58 children. ( Bhutta, ZA; Farooqui, BJ; Naqvi, SH, 1992) |
| "The antibiotic of choice for the treatment of typhoid fever in most parts of the world is still chloramphenicol." | 1.28 | Therapeutic implications of ofloxacin in the treatment of typhoid fever caused by multiply resistant Salmonella typhi. ( Ashfaq, MK; Farooqui, BJ; Ishaq, M; Khan, MA, 1990) |
| "Ofloxacin was well absorbed orally." | 1.28 | [Efficacy of ofloxacin in treating typhoid fever]. ( Gu, XJ; Wang, F; Zhang, MF, 1989) |
| "Recently we experienced two male typhoid patients who required additional treatment with CP sodium succinate (CP succinate) to OFLX therapy." | 1.28 | [Combination therapy with ofloxacin and chloramphenicol against typhoid fever]. ( Doi, H; Honda, S; Ichimura, H; Koda, T; Kurimura, O; Tamura, I, 1990) |
| "210 clinical isolates of typhoid salmonellae, cultivated from blood of patients with typhoid fever (108 strains of Salmonella typhi, 99 strains of Salmonella paratyphi A and three strains of Salmonella paratyphi B) as well as 266 random clinical isolates of Escherichia coli (n = 152), Klebsiella spp." | 1.27 | In vitro activity of ofloxacin against 210 clinical isolates of typhoid salmonellae. ( Hannan, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (20.90) | 18.7374 |
| 1990's | 22 (32.84) | 18.2507 |
| 2000's | 16 (23.88) | 29.6817 |
| 2010's | 12 (17.91) | 24.3611 |
| 2020's | 3 (4.48) | 2.80 |
| Authors | Studies |
|---|---|
| Fazaludeen Koya, S | 1 |
| Hasan Farooqui, H | 1 |
| Mehta, A | 1 |
| Selvaraj, S | 1 |
| Galea, S | 1 |
| Kuehn, R | 3 |
| Stoesser, N | 3 |
| Eyre, D | 3 |
| Darton, TC | 3 |
| Basnyat, B | 8 |
| Parry, CM | 9 |
| Pokharel, S | 1 |
| Karki, M | 1 |
| Acharya, B | 1 |
| Marasini, B | 1 |
| Arjyal, A | 6 |
| Thompson, CN | 2 |
| Karkey, A | 5 |
| Dongol, S | 5 |
| Wolbers, M | 2 |
| Darton, T | 1 |
| Farrar, JJ | 6 |
| Thwaites, GE | 1 |
| Dolecek, C | 4 |
| Baker, S | 6 |
| Bakthavatchalam, YD | 1 |
| Kumar, DT | 1 |
| Tayubi, IA | 1 |
| Shankar, BA | 1 |
| Babu, P | 1 |
| Munusamy, E | 1 |
| Thukkaram, B | 1 |
| Ravi, R | 1 |
| Doss, CGP | 1 |
| Veeraraghavan, B | 1 |
| Tiwaskar, M | 1 |
| Koirala, S | 1 |
| Shilpakar, O | 1 |
| Shrestha, K | 1 |
| Shrestha, R | 1 |
| Shrestha, UM | 2 |
| Agrawal, K | 1 |
| Koirala, KD | 2 |
| Thapa, SD | 2 |
| Giri, A | 2 |
| Shakya, M | 1 |
| Pathak, KR | 1 |
| Campbell, J | 1 |
| Farrar, J | 2 |
| Näsström, E | 1 |
| Vu Thieu, NT | 1 |
| Voong Vinh, P | 1 |
| Ha Thanh, T | 1 |
| Johansson, A | 1 |
| Thwaites, G | 2 |
| Antti, H | 1 |
| Blacksell, SD | 2 |
| Paris, DH | 1 |
| Day, N | 1 |
| Rasool, MH | 1 |
| Siddique, AB | 1 |
| Saqalein, M | 1 |
| Asghar, MJ | 1 |
| Zahoor, MA | 1 |
| Aslam, B | 1 |
| Shafiq, HB | 1 |
| Nisar, MA | 1 |
| Thapa, R | 1 |
| Banerjee, P | 1 |
| Akhtar, N | 1 |
| Jain, TS | 1 |
| Truusalu, K | 1 |
| Mikelsaar, RH | 1 |
| Naaber, P | 1 |
| Karki, T | 1 |
| Kullisaar, T | 1 |
| Zilmer, M | 1 |
| Mikelsaar, M | 1 |
| Duggal, S | 1 |
| Mahajan, RK | 1 |
| Biswas, NK | 1 |
| Chandel, DS | 1 |
| Duggal, N | 1 |
| Hans, C | 1 |
| Eberlein, M | 1 |
| Chahla, MF | 1 |
| Baierlein, SA | 1 |
| Mahon, RT | 1 |
| Gaborieau, V | 1 |
| Weill, FX | 1 |
| Marchou, B | 1 |
| Vinh, H | 6 |
| Chinh, NT | 2 |
| Wain, J | 9 |
| Campbell, JI | 1 |
| Hien, TT | 4 |
| Ali, MH | 1 |
| Rokonuzzaman, SM | 1 |
| Ahmed, MA | 1 |
| Uddin, MN | 1 |
| Haque, MA | 1 |
| Islam, MA | 1 |
| Garg, B | 1 |
| Madan, M | 1 |
| Kumar, V | 1 |
| Malhotra, R | 1 |
| Thanh, DP | 1 |
| Lobzin, IuV | 1 |
| Kovalenko, AN | 1 |
| Hanh, VT | 1 |
| Chinh, MT | 1 |
| House, D | 1 |
| Tham, CT | 1 |
| Thao, NT | 1 |
| Diep, TS | 4 |
| Day, NP | 5 |
| White, NJ | 9 |
| Duong, NM | 3 |
| Phuong, le T | 2 |
| Truong, NT | 1 |
| Bay, PV | 2 |
| Ho, VA | 2 |
| Phongmany, S | 1 |
| Phetsouvanh, R | 1 |
| Sisouphone, S | 1 |
| Darasavath, C | 1 |
| Vongphachane, P | 1 |
| Rattanavong, O | 1 |
| Mayxay, M | 1 |
| Ramsay, AC | 1 |
| Thammavong, C | 1 |
| Syhavong, B | 1 |
| Newton, PN | 1 |
| Kadhiravan, T | 1 |
| Wig, N | 1 |
| Kapil, A | 1 |
| Kabra, SK | 1 |
| Renuka, K | 1 |
| Misra, A | 1 |
| Hannan, A | 2 |
| Ahmed, SA | 1 |
| Akhtar, MA | 1 |
| Anwar, CM | 1 |
| Mahmood, S | 1 |
| Kaleem, M | 1 |
| Iqbal, M | 1 |
| Tanphaichitra, D | 3 |
| Srimuang, S | 3 |
| Kadam, GS | 1 |
| Naikwadi, A | 1 |
| Rao, SK | 1 |
| Sawardekar, SS | 1 |
| Gawde, A | 1 |
| Baliga, V | 1 |
| Desai, A | 1 |
| Nelwan, RH | 1 |
| Chen, K | 1 |
| Paramita, D | 1 |
| Lanh, MN | 1 |
| Tung, le T | 1 |
| Tham, NT | 1 |
| Kumar, R | 1 |
| Gupta, N | 1 |
| Dutta, S | 1 |
| Sur, D | 1 |
| Manna, B | 1 |
| Sen, B | 1 |
| Bhattacharya, M | 1 |
| Bhattacharya, SK | 1 |
| Nair, S | 1 |
| Clemens, JD | 1 |
| Ochiai, RL | 1 |
| Kurimura, O | 4 |
| Doi, H | 4 |
| Morioka, Y | 1 |
| Tran, TH | 1 |
| Bethell, DB | 3 |
| Nguyen, TT | 2 |
| To, SD | 1 |
| Le, TP | 1 |
| Bui, MC | 1 |
| Nguyen, MD | 2 |
| Pham, TT | 1 |
| Walsh, AL | 1 |
| Patel, AK | 1 |
| Kaji, BC | 1 |
| Declercq, J | 1 |
| Verhaegen, J | 1 |
| Verbist, L | 1 |
| Lammens, J | 1 |
| Stuyck, J | 1 |
| Fabry, G | 1 |
| Smith, MD | 1 |
| Hoa, NT | 1 |
| Ha, HD | 2 |
| Unlü, S | 1 |
| Arman, D | 1 |
| Altay, G | 1 |
| Hou, SR | 1 |
| Chakravorty, B | 1 |
| Jain, N | 1 |
| Gupta, B | 1 |
| Rajvanshi, P | 1 |
| Sen, MK | 1 |
| Krishna, A | 1 |
| Rathore, MH | 1 |
| Bux, D | 1 |
| Hasan, M | 1 |
| Phi, LT | 1 |
| Len, NV | 1 |
| Chuong, LV | 1 |
| Vo, TN | 1 |
| Cao, NN | 1 |
| Mai, TC | 1 |
| Bethell, D | 1 |
| Tu, SD | 1 |
| Dung, NM | 1 |
| McMullin, C | 1 |
| Loan, HT | 1 |
| Tam, DT | 1 |
| Minh, LT | 1 |
| Linh, NT | 1 |
| Dung, NQ | 1 |
| MacGowan, AP | 1 |
| White, LO | 1 |
| Seçmeer, G | 1 |
| Kanra, G | 1 |
| Figen, G | 1 |
| Akan, O | 1 |
| Ceyhan, M | 1 |
| Ecevit, Z | 1 |
| Kawashima, I | 1 |
| Suzuki, T | 1 |
| Suzuki, A | 1 |
| Obana, M | 1 |
| Suzuki, H | 1 |
| Matsuoka, Y | 1 |
| Irimajiri, S | 1 |
| Fukuda, J | 1 |
| Lu, M | 1 |
| Ji, B | 1 |
| Ouyang, K | 1 |
| Cao, XT | 1 |
| Kneen, R | 1 |
| Nguyen, TA | 1 |
| Truong, DL | 1 |
| Ly, NT | 1 |
| Thong, MX | 1 |
| Hazir, T | 1 |
| Qazi, SA | 1 |
| Abbas, KA | 1 |
| Khan, MA | 2 |
| Sasikumar, K | 1 |
| Ravishankar, NK | 1 |
| Satishchandra, P | 1 |
| Ooishi, A | 1 |
| Tamura, R | 1 |
| Naqvi, SH | 1 |
| Bhutta, ZA | 1 |
| Farooqui, BJ | 2 |
| Zou, QY | 1 |
| Wang, QN | 1 |
| Jiang, YF | 1 |
| Sabbour, MS | 1 |
| Osman, LM | 1 |
| Ishaq, M | 1 |
| Ashfaq, MK | 1 |
| Ichimura, H | 2 |
| Koda, T | 1 |
| Honda, S | 2 |
| Tamura, I | 2 |
| Gu, XJ | 2 |
| Zhang, MF | 2 |
| Wang, F | 2 |
| Tsubakio, T | 1 |
| Oomura, M | 1 |
| Cristiano, P | 2 |
| Iovene, MR | 1 |
| Morelli, G | 2 |
| Mandia, L | 1 |
| Paradisi, F | 2 |
| Altucci, P | 2 |
| Tai, TY | 1 |
| Sahaphong, S | 1 |
| Lo, WL | 1 |
| Peyramond, D | 1 |
| Tigaud, S | 1 |
| Lucht, F | 1 |
| Vedrinne, JM | 1 |
| Salord, F | 1 |
| Bertrand, JL | 1 |
| Stahl, JP | 1 |
| Leclercq, P | 1 |
| Croize, J | 1 |
| Lefebvre, MA | 1 |
| Bru, JP | 1 |
| Fourtillan, JB | 1 |
| Le Noc, P | 1 |
| Micoud, M | 1 |
| Leonessa, V | 1 |
| Briante, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Parallel Group, Double Blinded, 1:1, Randomized Controlled Phase III Trial of Co-trimoxazole Versus Azithromycin for the Treatment of Undifferentiated Fever In Nepal[NCT02773407] | Phase 3 | 330 participants (Actual) | Interventional | 2016-05-23 | Completed | ||
| Azithromycin and Cefixime Combination Versus Azithromycin Alone for the Out-patient Treatment of Clinically Suspected or Confirmed Uncomplicated Typhoid Fever in South Asia; a Randomised Controlled Trial[NCT04349826] | Phase 4 | 1,500 participants (Anticipated) | Interventional | 2021-05-23 | Recruiting | ||
| Long Term Protection by and Persistence of Vi Antibodies Induced by Vi-rEPA Conjugate Vaccines in Vietnamese Children Injected at 2-5 Years or at 5-8 Years of Age[NCT00386789] | 0 participants | Observational | 2006-10-05 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ofloxacin and Typhoid Fever
| Article | Year |
|---|---|
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone | 2022 |
22 trials available for ofloxacin and Typhoid Fever
| Article | Year |
|---|---|
Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Child; Drug Resistance, Multipl | 2017 |
Gatifloxacin versus ofloxacin for the treatment of uncomplicated enteric fever in Nepal: an open-label, randomized, controlled trial.
Topics: Adolescent; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gati | 2013 |
The influence of reduced susceptibility to fluoroquinolones in Salmonella enterica serovar Typhi on the clinical response to ofloxacin therapy.
Topics: Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Salmon | 2011 |
Effectiveness of levofloxacin in enteric fever.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Ofloxacin; Treat | 2011 |
Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever.
Topics: Acetaminophen; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distributi | 2004 |
Comparative trial of short-course ofloxacin for uncomplicated typhoid fever in Vietnamese children.
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Drug Administratio | 2005 |
A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos.
Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Chloramphenicol; Female; Health Care | 2005 |
Open study on efficacy and safety of levofloxacin in treatment of uncomplicated typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 2006 |
Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Blood Cell Count; Child; Child, Preschool; D | 2007 |
Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Blood Cell Count; Child; Child, Preschool; D | 2007 |
Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Blood Cell Count; Child; Child, Preschool; D | 2007 |
Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Blood Cell Count; Child; Child, Preschool; D | 2007 |
Multidrug-resistant typhoid fever.
Topics: Administration, Oral; Blood; Ceftriaxone; Chi-Square Distribution; Child; Child, Preschool; Drug Res | 2007 |
Short course of ofloxacin for treatment of multidrug-resistant typhoid.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Administration Schedule; Drug Resistance, Mic | 1995 |
Comparison of ofloxacin and ceftriaxone for short-course treatment of enteric fever.
Topics: Adolescent; Adult; Ceftriaxone; Drug Resistance, Microbial; Female; Humans; Male; Middle Aged; Oflox | 1994 |
[Clinical study of Chinese ofloxacin].
Topics: Adolescent; Adult; Aged; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxacin; Respiratory Tract | 1993 |
Effects on growth of single short courses of fluoroquinolones.
Topics: Adolescent; Anti-Infective Agents; Body Height; Child; Child, Preschool; Ciprofloxacin; Disease Outb | 1996 |
Two or three days of ofloxacin treatment for uncomplicated multidrug-resistant typhoid fever in children.
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Drug Resistance, Microbial; Female; Huma | 1996 |
Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever.
Topics: Administration, Oral; Adolescent; Anti-Infective Agents; Area Under Curve; Biological Availability; | 1996 |
A comparative study of ofloxacin and cefixime for treatment of typhoid fever in children. The Dong Nai Pediatric Center Typhoid Study Group.
Topics: Adolescent; Anti-Infective Agents; Cefixime; Cefotaxime; Cephalosporins; Child; Child, Preschool; Dr | 1999 |
A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Drug Resistance, Mult | 2000 |
A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Drug Resistance, Mult | 2000 |
A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Drug Resistance, Mult | 2000 |
A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Drug Resistance, Mult | 2000 |
Experience with ofloxacin in enteric fever.
Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Drug Administration Schedule; Fem | 1990 |
Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxa | 1986 |
Ofloxacin in treatment of typhoid fever: a preliminary study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Clinical Trials as Topic; Humans; Ofloxacin; Oxazines; Sal | 1988 |
Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cholangitis; Clinical Trials a | 1986 |
44 other studies available for ofloxacin and Typhoid Fever
| Article | Year |
|---|---|
Quantifying antibiotic use in typhoid fever in India: a cross-sectional analysis of private sector medical audit data, 2013-2015.
Topics: Anti-Bacterial Agents; Cefixime; Cephalosporins; Child; Cross-Sectional Studies; Drug Prescriptions; | 2022 |
Outbreak of acute undifferentiated febrile illness in Kathmandu, Nepal: clinical and epidemiological investigation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Cefixime; Child; Di | 2020 |
In vitro efficacy and in silico analysis of cefixime-ofloxacin combination for Salmonella Typhi from bloodstream infection.
Topics: Anti-Bacterial Agents; Bacteremia; Cefixime; Humans; India; Microbial Sensitivity Tests; Ofloxacin; | 2017 |
Cefixime-ofloxacin Combination in the Management of Uncomplicated Typhoid Fever in the Indian Community Setting.
Topics: Anti-Bacterial Agents; Cefixime; Drug Combinations; Humans; India; Ofloxacin; Salmonella typhi; Typh | 2019 |
Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever.
Topics: Area Under Curve; Bacterial Proteins; Biomarkers; Case-Control Studies; Fluoroquinolones; Gas Chroma | 2014 |
Undifferentiated febrile illness in Kathmandu, Nepal.
Topics: Anti-Bacterial Agents; Fever; Fluoroquinolones; Gatifloxacin; Humans; Nepal; Ofloxacin; Prospective | 2015 |
Occurrence and antibacterial susceptibility pattern of bacterial pathogens isolated from diarrheal patients in Pakistan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacillus cereus; Cef | 2016 |
Transient dysautonomia and cerebellitis in childhood enteric fever.
Topics: Anti-Bacterial Agents; Ataxia; Autonomic Nervous System; Ceftriaxone; Cerebellar Diseases; Cerebellu | 2008 |
Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin.
Topics: Animals; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Limosilactobacillus ferme | 2008 |
Splenic abscess due to Salmonella enterica Serotype typhi in a young adult.
Topics: Abdominal Abscess; Anti-Bacterial Agents; Ceftriaxone; Humans; Male; Metronidazole; Ofloxacin; Salmo | 2008 |
A fall in Ghana.
Topics: Accidental Falls; Adult; Anti-Bacterial Agents; Back Pain; Bacteremia; Diagnosis, Differential; Ghan | 2009 |
[A case of Salmonella enterica serovar typhi with decreased susceptibility to ciprofloxacin].
Topics: Anti-Bacterial Agents; Bacteremia; Ceftriaxone; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; | 2010 |
Sacroiliitis caused by Salmonella typhi: a case report.
Topics: Anti-Bacterial Agents; Blood Sedimentation; C-Reactive Protein; Diarrhea; Humans; Levofloxacin; Magn | 2011 |
Highly resistant Salmonella enterica serovar Typhi with a novel gyrA mutation raises questions about the long-term efficacy of older fluoroquinolones for treating typhoid fever.
Topics: Adolescent; Amino Acid Sequence; Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; DNA Gyrase | 2012 |
[Combined infection of abdominal typhoid and hepatitis A and E].
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Ciprofloxacin; Diagnosis, Diffe | 2003 |
Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhi.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefixime; Child; Child, Preschool; Ciprofloxacin; Drug Res | 2005 |
Ofloxacin--a possible breakthrough in the treatment of typhoid fever caused by chloramphenicol resistant Salmonella typhi.
Topics: Anti-Bacterial Agents; Chloramphenicol; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Te | 1989 |
In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Humans; Microbial Sensitivity Tes | 1989 |
Levofloxacin in enteric fever--a study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin | 2005 |
Emergence of highly fluoroquinolone-resistant Salmonella enterica serovar Typhi in a community-based fever surveillance from Kolkata, India.
Topics: Anti-Bacterial Agents; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Electrophoresis, | 2008 |
[Therapeutic effect of ofloxacin in a patient with typhoid fever].
Topics: Anti-Infective Agents; Female; Humans; Middle Aged; Ofloxacin; Oxazines; Typhoid Fever | 1984 |
Resistant Salmonella meningitis treated with oflaxacin--a quinolone compound.
Topics: Contraindications; Humans; Meningitis, Bacterial; Ofloxacin; Salmonella typhi; Typhoid Fever | 1994 |
Salmonella typhi osteomyelitis.
Topics: Adult; Cefotaxime; Forearm; Humans; Male; Ofloxacin; Osteomyelitis; Trimethoprim, Sulfamethoxazole D | 1994 |
[Ofloxacin treatment of salmonella infections].
Topics: Carrier State; Humans; Ofloxacin; Paratyphoid Fever; Salmonella Food Poisoning; Salmonella Infection | 1993 |
Chloramphenicol resistant enteric fever.
Topics: Adolescent; Adult; Chloramphenicol; Chloramphenicol Resistance; Ciprofloxacin; Female; Gentamicins; | 1993 |
Multidrug-resistant Salmonella typhi in Pakistani children: clinical features and treatment.
Topics: Ampicillin Resistance; Anti-Infective Agents; Cefotaxime; Ceftriaxone; Cephalosporins; Child; Child, | 1996 |
Ofloxacin versus co-trimoxazole in the treatment of typhoid fever in children.
Topics: Anti-Bacterial Agents; Child; Female; Humans; Male; Ofloxacin; Time Factors; Treatment Outcome; Trim | 1997 |
[A case report--typhoid fever complicated with liver and gallbladder abscess, treated for long-time as fever of unknown origin].
Topics: Abscess; Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Cholecystectomy; Diagnostic Errors; | 1997 |
[Clinical and laboratory studies with typhoid fever 178 patients].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Female; Hepatitis; Humans; Male; Microbial Se | 1997 |
Therapeutic re-appraisal of multiple drug resistant Salmonella typhi (MDRST) in Pakistani children.
Topics: Amoxicillin; Cefotaxime; Ceftriaxone; Child; Child, Preschool; Chloramphenicol; Drug Resistance, Mul | 2002 |
Resistant Salmonella meningitis treated with ofloxacin--a quinolone compound.
Topics: Administration, Oral; Adult; Humans; Male; Meningitis, Bacterial; Ofloxacin; Salmonella typhi; Typho | 1992 |
[Efficacy of levofloxacin on typhoid fever].
Topics: Aged; Female; Humans; Levofloxacin; Ofloxacin; Typhoid Fever | 1992 |
Therapy of multidrug resistant typhoid in 58 children.
Topics: Adolescent; Ampicillin Resistance; Aztreonam; Cefotaxime; Ceftriaxone; Child; Child, Preschool; Chlo | 1992 |
[Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea].
Topics: Adult; Dysentery, Bacillary; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Ag | 1991 |
Therapeutic implications of ofloxacin in the treatment of typhoid fever caused by multiply resistant Salmonella typhi.
Topics: Adult; Drug Resistance, Microbial; Humans; Ofloxacin; Salmonella typhi; Typhoid Fever | 1990 |
[Combination therapy with ofloxacin and chloramphenicol against typhoid fever].
Topics: Adolescent; Adult; Chloramphenicol; Drug Therapy, Combination; Humans; Male; Ofloxacin; Typhoid Feve | 1990 |
[Efficacy of ofloxacin in treating typhoid fever].
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Ofloxacin; Salmonella typhi; Typhoid Fever | 1989 |
[Studies on the clinical and bacteriological effects of ofloxacin on the typhoid patients and carriers].
Topics: Adult; Aged; Carrier State; Child; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; O | 1989 |
Clinical experience with ofloxacin (DL-8280) in the therapy of various infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Child; Female; Gastroenteritis; Humans; Male; Middle | 1989 |
Treatment of typhoid fever with ofloxacin.
Topics: Adolescent; Adult; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Salmon | 1989 |
In vitro activity of ofloxacin against 210 clinical isolates of typhoid salmonellae.
Topics: Anti-Bacterial Agents; Humans; Ofloxacin; Oxazines; Paratyphoid Fever; Salmonella; Salmonella paraty | 1986 |
In vitro and clinical evaluation of ofloxacin in urinary tract infection and enteric fever.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; beta-Lactamases; Enterobacteriaceae; Half-Life; Humans; | 1988 |
[Evaluation of the use of ofloxacin in the treatment of various infections].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Blood Bactericidal Activity; D | 1986 |
[Treatment of typhoid fever using ofloxacin. Clinical experience and determination of antibiotic diffusion into the mesenteric lymph nodes].
Topics: Adolescent; Adult; Anti-Infective Agents; Diffusion; Female; Humans; Lymph Nodes; Male; Mesentery; M | 1986 |