ofloxacin has been researched along with Tularemia in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Tularemia: A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.
| Excerpt | Relevance | Reference |
|---|---|---|
| " holarctica in a stem cell transplant recipient with chronic graft-versus-host disease who was receiving levofloxacin prophylaxis." | 3.79 | Treatment of tularemia in patient with chronic graft-versus-host disease. ( Kaufmann, M; Knabbe, C; Seibold, E; Splettstoesser, W; Weile, J, 2013) |
| "Pharmacokinetic and efficacy studies with levofloxacin were performed in the common marmoset (Callithrix jacchus) model of inhalational tularemia." | 3.76 | Bioavailability and efficacy of levofloxacin against Francisella tularensis in the common marmoset (Callithrix jacchus). ( Dean, RE; Lever, MS; Nelson, M; Pearce, PC; Simpson, AJ; Stevens, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weile, J | 1 |
| Seibold, E | 1 |
| Knabbe, C | 1 |
| Kaufmann, M | 1 |
| Splettstoesser, W | 1 |
| Klimpel, GR | 1 |
| Eaves-Pyles, T | 1 |
| Moen, ST | 1 |
| Taormina, J | 1 |
| Peterson, JW | 1 |
| Chopra, AK | 1 |
| Niesel, DW | 1 |
| Carness, P | 1 |
| Haithcoat, JL | 1 |
| Kirtley, M | 1 |
| Nasr, AB | 1 |
| Pyles, RB | 1 |
| Jezek, GE | 1 |
| Eaves-Pyles, TD | 1 |
| Nelson, M | 1 |
| Lever, MS | 1 |
| Dean, RE | 1 |
| Pearce, PC | 1 |
| Stevens, DJ | 1 |
| Simpson, AJ | 1 |
| Berton, M | 1 |
| Nojavan, H | 1 |
| Bens, G | 1 |
| Estève, E | 1 |
| Limaye, AP | 1 |
| Hooper, CJ | 1 |
| Aranda, EA | 1 |
| Syrjälä, H | 1 |
| Schildt, R | 1 |
| Räisäinen, S | 1 |
1 review available for ofloxacin and Tularemia
| Article | Year |
|---|---|
Treatment of tularemia with fluoroquinolones: two cases and review.
Topics: Adult; Anti-Infective Agents; Bacteremia; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Tulare | 1999 |
7 other studies available for ofloxacin and Tularemia
| Article | Year |
|---|---|
Treatment of tularemia in patient with chronic graft-versus-host disease.
Topics: Anti-Bacterial Agents; Chronic Disease; Doxycycline; Francisella tularensis; Graft vs Host Disease; | 2013 |
Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody.
Topics: Administration, Intranasal; Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Formatio | 2008 |
Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infection.
Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cells, Cultured; Colony Count, Microbi | 2010 |
Bioavailability and efficacy of levofloxacin against Francisella tularensis in the common marmoset (Callithrix jacchus).
Topics: Animals; Anti-Bacterial Agents; Callithrix; Chromatography, Liquid; Drug Administration Schedule; Fe | 2010 |
[Localized inflammatory alopecia of the scalp: an unusual presentation of tularemia].
Topics: Alopecia; Anti-Bacterial Agents; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Lymphatic | 2012 |
Treatment of tularemia with levofloxacin.
Topics: Aged; Anti-Infective Agents; Francisella tularensis; Humans; Levofloxacin; Male; Ofloxacin; Tularemi | 2001 |
In vitro susceptibility of Francisella tularensis to fluoroquinolones and treatment of tularemia with norfloxacin and ciprofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Francisella tularensis; Microbial Sensitivity Tests; Norfloxac | 1991 |