ofloxacin and Torsade de Pointes

ofloxacin has been researched along with Torsade de Pointes in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (69.23)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshar, H; Birnbaum, Y; Patel, PD1
Zeineh, NS1
Abo-Salem, E; Chance, W; Nugent, K1
Estes, LL; Wilson, JW; Zeuli, JD1
Al-Khatib, SM; Allen LaPointe, NM; Califf, RM; Curtis, LH; Dans, PE; Hutchison, S; Schulman, KA; Sendersky, V; Usdin Yasuda, S; Woosley, RL; Wright, A; Østbye, T1
Gandhi, PJ; Menezes, PA; Ramaswamy, K; Rivera, AL; Vu, HT1
Amankwa, K; Krishnan, SC; Tisdale, JE1
Cox, CD; Meyerrose, GE; Peeters, MJ; Seifert, CF; Tsikouris, JP1
Kawai, H; Komiya, M; Matsumoto, T; Nakayasu, T; Shimada, J; Yamaguchi, H; Yokoyama, H1
Breithardt, G; Cakir, Y; Eckardt, L; Engelen, MA; Haverkamp, W; Hilker, E; Milberg, P; Mönnig, G; Osada, N; Ramtin, S; Stypmann, J1
Chiba, K; Hashimoto, K; Satoh, Y; Shiina, H; Sugiyama, A1
Byazrova, E; Curciumaru, I; Doddamani, S; Iannini, PB; Kramer, H1
Frothingham, R1

Trials

1 trial(s) available for ofloxacin and Torsade de Pointes

ArticleYear
Effects of three fluoroquinolones on QT analysis after standard treatment courses.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2006, Volume: 11, Issue:1

    Topics: Analysis of Variance; Aza Compounds; Ciprofloxacin; Cross-Over Studies; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Levofloxacin; Long QT Syndrome; Male; Moxifloxacin; Ofloxacin; Quinolines; Statistics, Nonparametric; Torsades de Pointes

2006

Other Studies

12 other study(ies) available for ofloxacin and Torsade de Pointes

ArticleYear
Levofloxacin-induced torsades de pointes.
    Texas Heart Institute journal, 2010, Volume: 37, Issue:2

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Coronary Angiography; Diagnosis, Differential; Electrocardiography; Female; Heart Rate; Humans; Levofloxacin; Myocardial Infarction; Ofloxacin; Torsades de Pointes

2010
A toxic combination.
    The American journal of medicine, 2010, Volume: 123, Issue:8

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Drug Therapy, Combination; Electrocardiography; Heart Conduction System; Humans; Male; Myocardial Ischemia; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Torsades de Pointes

2010
Antibiotic-induced cardiac arrhythmia in elderly patients.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Humans; Male; Ofloxacin; Torsades de Pointes

2011
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Fluconazole; Hematologic Neoplasms; Humans; Hypokalemia; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Mycoses; Ofloxacin; Pyrimidines; Risk Factors; Torsades de Pointes; Triazoles; Ventricular Dysfunction, Left; Voriconazole

2013
Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients.
    The American journal of medicine, 2003, Feb-01, Volume: 114, Issue:2

    Topics: Adult; Aged; Amitriptyline; Anti-Bacterial Agents; Anti-Infective Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clarithromycin; Cohort Studies; Drug Prescriptions; Drug Synergism; Erythromycin; Female; Fluoxetine; Heart Conduction System; Humans; Male; Middle Aged; Ofloxacin; Outpatients; Polypharmacy; Torsades de Pointes; United States

2003
Fluconazole- and levofloxacin-induced torsades de pointes in an intensive care unit patient.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Dec-01, Volume: 60, Issue:23

    Topics: Anti-Infective Agents; Antifungal Agents; Fluconazole; Humans; Intensive Care Units; Levofloxacin; Male; Middle Aged; Monitoring, Physiologic; Ofloxacin; Torsades de Pointes; United States

2003
Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors.
    Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:3

    Topics: Aged; Cardiovascular Diseases; Female; Fluoroquinolones; Humans; Levofloxacin; Lupus Erythematosus, Systemic; Ofloxacin; Osteomyelitis; Risk Factors; Torsades de Pointes

2004
Post-marketing surveillance of the safety of levofloxacin in Japan.
    Chemotherapy, 2007, Volume: 53, Issue:2

    Topics: Achilles Tendon; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Chemical and Drug Induced Liver Injury; Female; Humans; Hypoglycemia; Japan; Levofloxacin; Liver Diseases; Long QT Syndrome; Male; Middle Aged; Ofloxacin; Photosensitivity Disorders; Product Surveillance, Postmarketing; Seizures; Torsades de Pointes

2007
Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes.
    Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:6

    Topics: Action Potentials; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Fluoroquinolones; Heart Conduction System; In Vitro Techniques; Levofloxacin; Male; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Rabbits; Torsades de Pointes

2007
Proarrhythmic effects of fluoroquinolone antibacterial agents: in vivo effects as physiologic substrate for torsades.
    Toxicology and applied pharmacology, 2000, Nov-15, Volume: 169, Issue:1

    Topics: Action Potentials; Animals; Anti-Infective Agents; Dogs; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart; Heart Block; Levofloxacin; Long QT Syndrome; Male; Models, Animal; Ofloxacin; Torsades de Pointes; Ventricular Dysfunction, Right

2000
Risk of torsades de pointes with non-cardiac drugs. Prolongation of QT interval is probably a class effect of fluoroquinolones.
    BMJ (Clinical research ed.), 2001, Jan-06, Volume: 322, Issue:7277

    Topics: Anti-Infective Agents; Electrocardiography; Humans; Ofloxacin; Torsades de Pointes

2001
Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin.
    Pharmacotherapy, 2001, Volume: 21, Issue:12

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Electrocardiography; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Retrospective Studies; Torsades de Pointes

2001