Page last updated: 2024-11-01

ofloxacin and Testicular Diseases

ofloxacin has been researched along with Testicular Diseases in 1 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Testicular Diseases: Pathological processes of the TESTIS.

Research Excerpts

ExcerptRelevanceReference
"Ofloxacin was also used to establish a dose-response relationship in doses of 36, 72 and 360 mg kg(-1) day(-1) p."1.31Adverse testicular effects of some quinolone members in rats. ( Abd-Allah, AR; Abdel-Aziz, AA; Aly, HA; Hamada, FM; Moustafa, AM, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abd-Allah, AR1
Aly, HA1
Moustafa, AM1
Abdel-Aziz, AA1
Hamada, FM1

Other Studies

1 other study available for ofloxacin and Testicular Diseases

ArticleYear
Adverse testicular effects of some quinolone members in rats.
    Pharmacological research, 2000, Volume: 41, Issue:2

    Topics: Acid Phosphatase; Animals; Anti-Infective Agents; Ciprofloxacin; Fertility; L-Lactate Dehydrogenase;

2000