ofloxacin has been researched along with Syndrome in 12 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously reported that a 6-month low-dose course of ofloxacin combined with long-term low-dose erythromycin therapy (EM therapy) was superior to EM therapy alone for sinobronchial syndrome (SBS), especially during the initial 2 months of treatment." | 9.10 | Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome. ( Fujimura, M; Mizuguchi, M; Mizuhashi, K; Nakatsumi, Y; Sasaki, S; Yasui, M, 2002) |
| "It has been established that long-term low-dose erythromycin therapy (EM therapy) is very effective for sinobronchial syndrome, a common condition in Japan characterized by chronic upper and lower airway inflammation." | 9.08 | Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. ( Fujimura, M; Ishiura, Y; Matsuda, T; Nakatsumi, Y; Nomura, M; Saito, M; Shibata, K, 1995) |
| "We previously reported that a 6-month low-dose course of ofloxacin combined with long-term low-dose erythromycin therapy (EM therapy) was superior to EM therapy alone for sinobronchial syndrome (SBS), especially during the initial 2 months of treatment." | 5.10 | Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome. ( Fujimura, M; Mizuguchi, M; Mizuhashi, K; Nakatsumi, Y; Sasaki, S; Yasui, M, 2002) |
| "It has been established that long-term low-dose erythromycin therapy (EM therapy) is very effective for sinobronchial syndrome, a common condition in Japan characterized by chronic upper and lower airway inflammation." | 5.08 | Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. ( Fujimura, M; Ishiura, Y; Matsuda, T; Nakatsumi, Y; Nomura, M; Saito, M; Shibata, K, 1995) |
| " Monitoring for toxicity is incompletely reliable in identifying all potential serious side effects such as the "temafloxacin syndrome." | 4.79 | Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety. ( Goldstein, EJ, 1996) |
| " We diagnosed Legionnaires' pneumonia accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS), and started treatment with ciprofloxacin and methylprednisolone at 1 mg/kg/day." | 3.77 | [A case of Legionnaires' pneumonia accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) with transient altered mental status and cerebellar symptoms, which responded to treatment by antibiotics and corticoste ( Akazawa, K; Hibi, M; Hibino, M; Hikino, K; Oe, M, 2011) |
| "Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the red man syndrome ." | 3.71 | Uncommon vancomycin-induced side effects. ( Baptista, MI; Da Cunha, CA; Kondo, W; Martins, LT; Rocha, JL, 2002) |
| "The clinical features of the dry eye and ocular surface disease and management issues are discussed." | 1.35 | Management of evaporative dry eye in ectrodactyly-ectodermal dysplasia-clefting syndrome. ( Dogru, M; Endo, K; Goto, E; Matsumoto, Y; Ota, Y; Tsubota, K; Uchino, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marchant, J | 1 |
| Ota, Y | 1 |
| Matsumoto, Y | 1 |
| Dogru, M | 1 |
| Goto, E | 1 |
| Uchino, Y | 1 |
| Endo, K | 1 |
| Tsubota, K | 1 |
| Chee, E | 1 |
| Looi, A | 1 |
| Jun, EJ | 1 |
| Chung, SK | 1 |
| Hibino, M | 1 |
| Hibi, M | 1 |
| Akazawa, K | 1 |
| Hikino, K | 1 |
| Oe, M | 1 |
| Rocha, JL | 1 |
| Kondo, W | 1 |
| Baptista, MI | 1 |
| Da Cunha, CA | 1 |
| Martins, LT | 1 |
| Fujimura, M | 3 |
| Mizuguchi, M | 1 |
| Nakatsumi, Y | 3 |
| Mizuhashi, K | 1 |
| Sasaki, S | 1 |
| Yasui, M | 1 |
| Savitskaia, KI | 1 |
| Tsar'kova, LN | 1 |
| Shanina, AG | 1 |
| Nasonov, VN | 1 |
| Solodilova, OE | 1 |
| Rusanova, EV | 1 |
| Ishiura, Y | 2 |
| Saito, M | 2 |
| Shibata, K | 2 |
| Nomura, M | 2 |
| Matsuda, T | 2 |
| Goldstein, EJ | 1 |
| Nickel, JC | 1 |
| Downey, J | 1 |
| Johnston, B | 1 |
| Clark, J | 1 |
1 review available for ofloxacin and Syndrome
| Article | Year |
|---|---|
Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Fluoroquinolones; Humans; Levoflox | 1996 |
5 trials available for ofloxacin and Syndrome
| Article | Year |
|---|---|
Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Bronchiolitis; Bronchitis; Drug Therapy, Combina | 2002 |
[Use of ofloxacin in the treatment of infections of the lower respiratory tract].
Topics: Adolescent; Adult; Asthma; Bronchitis; Chronic Disease; Female; Gram-Negative Bacterial Infections; | 1994 |
Additive effect of continuous low dose ofloxacin on erythromycin therapy for sinobronchial syndrome.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bronchitis; Drug Thera | 1995 |
Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Carbocysteine; Drug Administratio | 1995 |
Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibodies, Bacterial; Bacteria; Bacterial In | 2001 |
6 other studies available for ofloxacin and Syndrome
| Article | Year |
|---|---|
When antibiotics turn toxic.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antioxidants; Ciprofloxacin; Female; Fluoroquinolon | 2018 |
Management of evaporative dry eye in ectrodactyly-ectodermal dysplasia-clefting syndrome.
Topics: Adult; Corneal Diseases; Dry Eye Syndromes; Ectodermal Dysplasia; Eye Abnormalities; Foot Deformitie | 2008 |
Onodi sinusitis presenting with orbital apex syndrome.
Topics: Abscess; Anti-Bacterial Agents; Combined Modality Therapy; Drainage; Drug Therapy, Combination; Ethm | 2009 |
Toxic anterior segment syndrome after cataract surgery.
Topics: Aged; Anterior Eye Segment; Corneal Edema; Drug Therapy, Combination; Endotoxins; Female; Humans; Ke | 2010 |
[A case of Legionnaires' pneumonia accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) with transient altered mental status and cerebellar symptoms, which responded to treatment by antibiotics and corticoste
Topics: Adrenal Cortex Hormones; Cerebellar Ataxia; Corpus Callosum; Encephalitis; Humans; Legionnaires' Dis | 2011 |
Uncommon vancomycin-induced side effects.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Eosinophilia; Erythema; Female; Fever; Hip Pros | 2002 |