ofloxacin and Stroke
ofloxacin has been researched along with Stroke in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Levofloxacin and placebo patients had a cumulative rate of infection of 6% and 6% (P=0." | 5.11 | The Early Systemic Prophylaxis of Infection After Stroke study: a randomized clinical trial. ( Cervera, A; Chamorro, A; Horcajada, JP; Mensa, J; Obach, V; Planas, AM; Revilla, M; Torres, F; Vargas, M, 2005) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Redondo, M | 1 |
| Zarruk, JG | 1 |
| Ceballos, P | 1 |
| Pérez, DI | 1 |
| Pérez, C | 1 |
| Perez-Castillo, A | 1 |
| Moro, MA | 1 |
| Brea, J | 1 |
| Val, C | 1 |
| Cadavid, MI | 1 |
| Loza, MI | 1 |
| Campillo, NE | 1 |
| Martínez, A | 1 |
| Gil, C | 1 |
| Chamorro, A | 1 |
| Horcajada, JP | 1 |
| Obach, V | 1 |
| Vargas, M | 1 |
| Revilla, M | 1 |
| Torres, F | 1 |
| Cervera, A | 1 |
| Planas, AM | 1 |
| Mensa, J | 1 |
Trials
1 trial available for ofloxacin and Stroke
| Article | Year |
|---|---|
The Early Systemic Prophylaxis of Infection After Stroke study: a randomized clinical trial.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Body Temperature; Brain; Brain Ischemia; C-React | 2005 |
Other Studies
1 other study available for ofloxacin and Stroke
| Article | Year |
|---|---|
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.
Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease | 2012 |