ofloxacin has been researched along with Staphylococcal Infections in 158 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Staphylococcal Infections: Infections with bacteria of the genus STAPHYLOCOCCUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levofloxacin is a synthetic fluoroquinolone that is usually used to treat chronic bacterial prostatitis." | 9.16 | Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients. ( Guo, YL; Jin, FS; Liu, DM; Shen, ZJ; Sun, YH; Zhang, ZC, 2012) |
| "The authors had for aim to evaluate the efficacy and tolerance of oral levofloxacin (500 mg once a day during ten days), as a treatment for acute bacterial sinusitis at risk for complications in adult patients." | 9.11 | [Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications]. ( Gehanno, P; Pessey, JJ; Serrano, E, 2005) |
| "The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections." | 9.10 | [Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003) |
| "Comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)." | 9.08 | Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group. ( Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D, 1998) |
| "The experience with lomefloxacin and ofloxacin respectively in the complex therapy of 26 and 40 patients with burns is described." | 9.08 | [Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns]. ( Alekseev, AA; Bobrovnikov, AE; Elagina, LV; Grishina, IA; Iakovlev, VP; Izotova, GN; Krutikov, MG, 1998) |
| " To this day, no other case of prostatic abscess due to this strain but susceptible to methicillin has been described." | 7.80 | Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureus producing Panton-Valentine leukocidin. ( Barraud, O; Brakbi, Y; Cypierre, A; Dubos, M; Fedou, AL; François, B; Fredon, F; Laurent, F, 2014) |
| "We investigated whether the foldable capsular vitreous body (FCVB) could release levofloxacin sustainably in vitro and inhibit endophthalmitis in rabbit models." | 7.79 | A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits. ( Feng, L; Gao, Q; Huang, X; Jiang, Z; Li, Y; Lin, J; Lin, X; Liu, Y; Wang, T; Xie, Z, 2013) |
| "The objective of the present study was to evaluate the effectiveness of topically applied gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis in a rabbit model." | 7.78 | Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis. ( Chen, H; Jiang, H; Liu, T; Song, Z; Wu, X; Xu, Y; Yang, L; Yue, W, 2012) |
| "The aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (NIH-II) in the daily clinical routine of urologists in their practices." | 7.77 | [Practice management of chronic bacterial prostatitis with levofloxacin]. ( Naber, KG; Roscher, K; Wagenlehner, F, 2011) |
| "5% levofloxacin in rabbits, and to determine its improved efficacy against experimental keratitis." | 7.76 | Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis. ( Chen, H; Jiang, HR; Wu, XG; Xin, M; Yang, LN, 2010) |
| "In the rabbit keratitis model, the ocular inflammation was significantly reduced by gatifloxacin as compared to levofloxacin but there was no significant difference between the groups in the number of viable bacteria." | 7.74 | Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis. ( Inoue, T; Kida, T; Naka, H; Sakaki, H; Tokushige, H; Wada, T, 2008) |
| "5% levofloxacin versus combined treatment with vancomycin and ceftazidime in an experimental model of bacterial endophthalmitis." | 7.74 | Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis. ( Abad, JL; Alió, JL; Fernandez, J; Ferrer, C; Rodríguez, A, 2008) |
| "Taurolidine is a broad-spectrum, non antibiotic antimicrobial agent, not previously tested against the common causes of bacterial keratitis." | 7.73 | Effectiveness of topical taurolidine versus ciprofloxacin, ofloxacin, and fortified cefazolin in a rabbit Staphylococcus aureus keratitis model. ( Gurkan, T; Oguz, E; Oguz, H; Ozbilge, H, 2005) |
| "3% ofloxacin solution) on methicillin-resistant Staphylococcus aureus (MRSA) keratitis were compared in a rabbit model." | 7.73 | Antibiotic effects of WP-0405, a thermo-setting ofloxacin gel, on methicillin-resistant Staphylococcus aureus keratitis in rabbits. ( Fukaya, Y; Hirata, H; Kamata, Y; Kambara, Y; Kurasawa, N; Kurita, A; Naito, A; Nakaya, S; Ohashi, Y; Sato, M; Shirasawa, E; Toyoda, Y; Tsuruga, H; Wada, T, 2006) |
| " In this study we investigate the emergence of fluoroquinolone (ciprofloxacin, levofloxacin) resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis." | 7.72 | Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis. ( Alfonso, EC; Marangon, FB; Miller, D; Muallem, MS; Romano, AC, 2004) |
| "The purpose of this study was to quantitatively compare, in a rabbit keratitis model, the levels of effectiveness of moxifloxacin, levofloxacin, and ciprofloxacin for the treatment of Staphylococcus aureus isolates of diverse antibiotic susceptibilities." | 7.72 | Effectiveness of ciprofloxacin, levofloxacin, or moxifloxacin for treatment of experimental Staphylococcus aureus keratitis. ( Dajcs, JJ; Girgis, DO; Marquart, ME; O'Callaghan, RJ; Thibodeaux, BA; Traidej, M, 2004) |
| "Methicillin-susceptible Staphylococcus aureus (MSSA) is the most common pathogen recovered from osteomyelitis patients." | 7.71 | Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits. ( Calhoun, JH; Mader, JT; Shirtliff, ME, 2001) |
| "To compare the antibacterial effect of povidone-iodine (PI) with that of ofloxacin in an experimental model of bacterial keratitis." | 7.70 | Effect of topical povidone-iodine versus topical ofloxacin on experimental Staphylococcus keratitis. ( Goldberg, MA; Lustbader, J; MacDowell, AL; Melki, SA; Safar, A; Scharper, M; Scharper, P; Yaghouti, F; Zeligs, B, 2000) |
| " This study, employing an experimental rabbit model of Staphylococcus keratitis, compared the effectiveness of two commonly prescribed formulations of fluoroquinolones to an experimental formulation, ciprofloxacin with polystyrene sulfonate (ciprofloxacin-PSS)." | 7.70 | Effectiveness of ciprofloxacin-polystyrene sulfonate (PSS), ciprofloxacin and ofloxacin in a Staphylococcus keratitis model. ( Engel, LS; Green, LC; Hill, JM; Moreau, JM; O'Callaghan, RJ, 1998) |
| "We investigated the use of an ofloxacin-impregnated bioabsorbable composite for the prevention of acute Staphylococcus aureus osteomyelitis." | 7.70 | Prophylaxis of acute osteomyelitis with absorbable ofloxacin-impregnated beads. ( Kourea, HP; Nicolau, DP; Nie, L; Nightingale, CH; Tessier, PR, 1998) |
| "The therapeutic effects of nimodipine (CAS 66085-59-4) and ofloxacin (CAS 82419-36-1) were investigated against experimental brain abscess formation in rats." | 7.69 | Effects of nimodipine and ofloxacin on staphylococcal brain abscesses in rats. ( Ceviz, A; Ciçek, R; Gül, K; Inalöz, SS; Sanli, A; Sari, I, 1997) |
| "We studied the efficacies of ofloxacin, rifampin, and clindamycin in a Staphylococcus aureus abscess model and seven antimicrobial regimens in an intracellular killing assay." | 7.69 | Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing. ( Bamberger, DM; Chern, RP; Dew, M; Herndon, BL; Kim, SC; Marcus, RF; Mitchell, H; Summers, LE; Suvarna, PR, 1997) |
| " In a murine model of hematogenous pyelonephritis, the in vivo efficacies of levofloxacin and ciprofloxacin were evaluated against two methicillin-susceptible and two methicillin-resistant S." | 7.69 | In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains. ( Barrett, JF; Frosco, MB; Kulwich, BA; Licata, L; Melton, JL; Stewart, FP, 1996) |
| "Eighteen episodes of peritonitis in 16 CAPD patients were treated with oral ofloxacin 400 mg initially, followed by 300 mg daily for a total of 10 days." | 7.67 | Oral treatment of peritonitis in CAPD patients with ofloxacin. ( Chan, MK; Chan, WW; Chau, PY, 1988) |
| "The study shows that it is possible to treat complicated urinary tract infections just as successfully with 200 mg i." | 6.67 | Comparison of i.v. ofloxacin and piperacillin in the treatment of complicated urinary tract infections. ( Schalkhäuser, K, 1990) |
| "Bacterial keratitis is a serious infectious ocular disease requiring prompt treatment to prevent frequent and severe visual disabilities." | 5.32 | A mucoadhesive polymer extracted from tamarind seed improves the intraocular penetration and efficacy of rufloxacin in topical treatment of experimental bacterial keratitis. ( Boldrini, E; Campa, M; Celandroni, F; Davini, P; Ghelardi, E; Parisio, E; Salvetti, S; Senesi, S; Tavanti, A, 2004) |
| "Levofloxacin is a synthetic fluoroquinolone that is usually used to treat chronic bacterial prostatitis." | 5.16 | Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients. ( Guo, YL; Jin, FS; Liu, DM; Shen, ZJ; Sun, YH; Zhang, ZC, 2012) |
| "The authors had for aim to evaluate the efficacy and tolerance of oral levofloxacin (500 mg once a day during ten days), as a treatment for acute bacterial sinusitis at risk for complications in adult patients." | 5.11 | [Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications]. ( Gehanno, P; Pessey, JJ; Serrano, E, 2005) |
| "The objective of this open-label, single-arm, multicenter study was to assess the efficacy and safety of levofloxacin in the treatment of complicated urinary tract infections." | 5.10 | [Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections]. ( Marchetti, F; Trinchieri, A, 2003) |
| "Levofloxacin is a useful quinolone for patients infected with osteomyelitis or tuberculosis." | 5.09 | [Tolerability and safety of levofloxacinin long-term treatment]. ( Almela, M; Alvárez, JL; García, S; Mensa, J; Ortega, M; Soriano, A; Soriano, E; Tomás, X, 2000) |
| "Ofloxacin and combined fortified tobramycin and cefazolin topical drops were comparable for treating cases of bacterial corneal ulcer." | 5.09 | Comparison of topical 0.3% ofloxacin with fortified tobramycin plus cefazolin in the treatment of bacterial keratitis. ( Ahuja, R; Panda, A; Sastry, SS, 1999) |
| "The experience with lomefloxacin and ofloxacin respectively in the complex therapy of 26 and 40 patients with burns is described." | 5.08 | [Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns]. ( Alekseev, AA; Bobrovnikov, AE; Elagina, LV; Grishina, IA; Iakovlev, VP; Izotova, GN; Krutikov, MG, 1998) |
| "Comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)." | 5.08 | Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group. ( Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D, 1998) |
| " To this day, no other case of prostatic abscess due to this strain but susceptible to methicillin has been described." | 3.80 | Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureus producing Panton-Valentine leukocidin. ( Barraud, O; Brakbi, Y; Cypierre, A; Dubos, M; Fedou, AL; François, B; Fredon, F; Laurent, F, 2014) |
| "We investigated whether the foldable capsular vitreous body (FCVB) could release levofloxacin sustainably in vitro and inhibit endophthalmitis in rabbit models." | 3.79 | A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits. ( Feng, L; Gao, Q; Huang, X; Jiang, Z; Li, Y; Lin, J; Lin, X; Liu, Y; Wang, T; Xie, Z, 2013) |
| "The objective of the present study was to evaluate the effectiveness of topically applied gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis in a rabbit model." | 3.78 | Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis. ( Chen, H; Jiang, H; Liu, T; Song, Z; Wu, X; Xu, Y; Yang, L; Yue, W, 2012) |
| "The aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (NIH-II) in the daily clinical routine of urologists in their practices." | 3.77 | [Practice management of chronic bacterial prostatitis with levofloxacin]. ( Naber, KG; Roscher, K; Wagenlehner, F, 2011) |
| "5% levofloxacin in rabbits, and to determine its improved efficacy against experimental keratitis." | 3.76 | Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis. ( Chen, H; Jiang, HR; Wu, XG; Xin, M; Yang, LN, 2010) |
| "5% levofloxacin versus combined treatment with vancomycin and ceftazidime in an experimental model of bacterial endophthalmitis." | 3.74 | Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis. ( Abad, JL; Alió, JL; Fernandez, J; Ferrer, C; Rodríguez, A, 2008) |
| "In the rabbit keratitis model, the ocular inflammation was significantly reduced by gatifloxacin as compared to levofloxacin but there was no significant difference between the groups in the number of viable bacteria." | 3.74 | Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis. ( Inoue, T; Kida, T; Naka, H; Sakaki, H; Tokushige, H; Wada, T, 2008) |
| "In vitro evidence of synergy between glycopeptides, fluoroquinolones (levofloxacin) and beta-lactams and of reduction of mutational frequencies by combinations are suggestive for a potential role in empirical therapy of severe pneumonia with suspected MRSA etiology." | 3.74 | In vitro evaluation of antibiotics' combinations for empirical therapy of suspected methicillin resistant Staphylococcus aureus severe respiratory infections. ( De Vecchi, E; Drago, L; Gismondo, MR; Nicola, L, 2007) |
| " Recently, the use of high doses of levofloxacin with rifampin has been recommended for staphylococcal infections." | 3.73 | Efficacy of high doses of levofloxacin in experimental foreign-body infection by methicillin-susceptible Staphylococcus aureus. ( Ariza, J; Cabellos, C; Doménech, A; Garcia, A; Gudiol, F; Murillo, O; Tubau, F, 2006) |
| "3% ofloxacin solution) on methicillin-resistant Staphylococcus aureus (MRSA) keratitis were compared in a rabbit model." | 3.73 | Antibiotic effects of WP-0405, a thermo-setting ofloxacin gel, on methicillin-resistant Staphylococcus aureus keratitis in rabbits. ( Fukaya, Y; Hirata, H; Kamata, Y; Kambara, Y; Kurasawa, N; Kurita, A; Naito, A; Nakaya, S; Ohashi, Y; Sato, M; Shirasawa, E; Toyoda, Y; Tsuruga, H; Wada, T, 2006) |
| "Taurolidine is a broad-spectrum, non antibiotic antimicrobial agent, not previously tested against the common causes of bacterial keratitis." | 3.73 | Effectiveness of topical taurolidine versus ciprofloxacin, ofloxacin, and fortified cefazolin in a rabbit Staphylococcus aureus keratitis model. ( Gurkan, T; Oguz, E; Oguz, H; Ozbilge, H, 2005) |
| "The purpose of this study was to quantitatively compare, in a rabbit keratitis model, the levels of effectiveness of moxifloxacin, levofloxacin, and ciprofloxacin for the treatment of Staphylococcus aureus isolates of diverse antibiotic susceptibilities." | 3.72 | Effectiveness of ciprofloxacin, levofloxacin, or moxifloxacin for treatment of experimental Staphylococcus aureus keratitis. ( Dajcs, JJ; Girgis, DO; Marquart, ME; O'Callaghan, RJ; Thibodeaux, BA; Traidej, M, 2004) |
| " In this study we investigate the emergence of fluoroquinolone (ciprofloxacin, levofloxacin) resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis." | 3.72 | Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis. ( Alfonso, EC; Marangon, FB; Miller, D; Muallem, MS; Romano, AC, 2004) |
| "The fourth-generation fluoroquinolone, gatifloxacin, is an effective prophylaxis against the development of keratitis after lamellar keratectomy in rabbits with an organism resistant to methicillin, levofloxacin, and ciprofloxacin." | 3.72 | Fluoroquinolone therapy in multiple-drug resistant staphylococcal keratitis after lamellar keratectomy in a rabbit model. ( Carpenter, TR; Kaufman, MB; McDonnell, PJ; Sarayba, MA; Sweet, PM; Taban, M; Tungsiripat, T, 2003) |
| "Methicillin-susceptible Staphylococcus aureus (MSSA) is the most common pathogen recovered from osteomyelitis patients." | 3.71 | Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits. ( Calhoun, JH; Mader, JT; Shirtliff, ME, 2001) |
| " This study, employing an experimental rabbit model of Staphylococcus keratitis, compared the effectiveness of two commonly prescribed formulations of fluoroquinolones to an experimental formulation, ciprofloxacin with polystyrene sulfonate (ciprofloxacin-PSS)." | 3.70 | Effectiveness of ciprofloxacin-polystyrene sulfonate (PSS), ciprofloxacin and ofloxacin in a Staphylococcus keratitis model. ( Engel, LS; Green, LC; Hill, JM; Moreau, JM; O'Callaghan, RJ, 1998) |
| "Vitreous levels of ofloxacin were above the MIC(90) at 2 and 8 h in all groups for most of the common microorganisms causing endophthalmitis and also at 24 h in traumatized-infected eyes." | 3.70 | Ofloxacin levels after intravitreal injection. Effects of trauma and inflammation. ( Basci, NE; Bozkurt, A; Kortunay, S; Kurt, E; Oguz Kayaalp, S; Oztürk, F; Sami Ilker, S; Ubeyt Inan, U, 1999) |
| "To compare the antibacterial effect of povidone-iodine (PI) with that of ofloxacin in an experimental model of bacterial keratitis." | 3.70 | Effect of topical povidone-iodine versus topical ofloxacin on experimental Staphylococcus keratitis. ( Goldberg, MA; Lustbader, J; MacDowell, AL; Melki, SA; Safar, A; Scharper, M; Scharper, P; Yaghouti, F; Zeligs, B, 2000) |
| "We investigated the use of an ofloxacin-impregnated bioabsorbable composite for the prevention of acute Staphylococcus aureus osteomyelitis." | 3.70 | Prophylaxis of acute osteomyelitis with absorbable ofloxacin-impregnated beads. ( Kourea, HP; Nicolau, DP; Nie, L; Nightingale, CH; Tessier, PR, 1998) |
| " In a murine model of hematogenous pyelonephritis, the in vivo efficacies of levofloxacin and ciprofloxacin were evaluated against two methicillin-susceptible and two methicillin-resistant S." | 3.69 | In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains. ( Barrett, JF; Frosco, MB; Kulwich, BA; Licata, L; Melton, JL; Stewart, FP, 1996) |
| "We studied the efficacies of ofloxacin, rifampin, and clindamycin in a Staphylococcus aureus abscess model and seven antimicrobial regimens in an intracellular killing assay." | 3.69 | Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing. ( Bamberger, DM; Chern, RP; Dew, M; Herndon, BL; Kim, SC; Marcus, RF; Mitchell, H; Summers, LE; Suvarna, PR, 1997) |
| "The therapeutic effects of nimodipine (CAS 66085-59-4) and ofloxacin (CAS 82419-36-1) were investigated against experimental brain abscess formation in rats." | 3.69 | Effects of nimodipine and ofloxacin on staphylococcal brain abscesses in rats. ( Ceviz, A; Ciçek, R; Gül, K; Inalöz, SS; Sanli, A; Sari, I, 1997) |
| "Ofloxacine (Tarivid-Hoechst) was used in 30 patients with infections of the respiratory system, including 12 with pneumonias, 18 with chronic bronchitis." | 3.68 | [Evaluation of the effectiveness of ofloxacin in the treatment of respiratory tract]. ( Chyrek-Borowska, S; Jakubicz, P; Siergiejko, Z, 1991) |
| "Ofloxacin, a new pyridone-carboxylic acid derivative, was evaluated in descending nephritis and subcutaneous abscess models with Staphylococcus aureus in mice in comparison with norfloxacin." | 3.67 | Chemotherapeutic efficacy of ofloxacin on renal and subcutaneous infection models with Staphylococcus aureus in mice. ( Fujimoto, T; Katami, K; Osada, Y; Sato, M; Tachizawa, H; Tsumura, M; Une, T, 1986) |
| " It was used alone 26 times and on 6 occasions it was associated with rifampin on 6 staphylococcal infections." | 3.67 | [Ofloxacin (RU 43280). Clinical study]. ( Bertrand, A; Despaux, E; Janbon, F; Jonquet, O; Reynes, J, 1987) |
| "Eighteen episodes of peritonitis in 16 CAPD patients were treated with oral ofloxacin 400 mg initially, followed by 300 mg daily for a total of 10 days." | 3.67 | Oral treatment of peritonitis in CAPD patients with ofloxacin. ( Chan, MK; Chan, WW; Chau, PY, 1988) |
| "The effect of a single day treatment with 600 mg norfloxacin 600 mg ofloxacin or 1,920 mg trimethoprim-sulfamethoxazol was determined on 114 patients with acute cystitis." | 3.67 | [Single day treatment in acute cystitis]. ( Kawaguchi, K; Yamaguchi, K, 1988) |
| " Drug-related adverse events were reported by 8." | 2.69 | A multicentre, double-blind, randomised study comparing the efficacy and safety of oral levofloxacin versus ciprofloxacin in the treatment of uncomplicated skin and skin structure infections. ( Jasovich, A; Neto, W; Nicodemo, AC; Robledo, JA, 1998) |
| "The study shows that it is possible to treat complicated urinary tract infections just as successfully with 200 mg i." | 2.67 | Comparison of i.v. ofloxacin and piperacillin in the treatment of complicated urinary tract infections. ( Schalkhäuser, K, 1990) |
| "Ofloxacin therapy was administered an average of 45 days per patient, and was well tolerated." | 2.67 | Oral ofloxacin for infections caused by bacteria resistant to oral antimicrobial agents. ( Eron, LJ; Gentry, LO, 1992) |
| " The choice of the initial dosage regimen actually takes into account toxicological, bacteriological and pharmacokinetic parameters." | 2.67 | A new approach to optimal antibiotic dosage regimen by coupling pharmacokinetics and killing curve parameters. ( Dellamonica, P; Drugeon, HB; Etesse, H; Garraffo, R; Lapalus, P, 1990) |
| "Ofloxacin was administered at a dose of 200 mg every 12 hours for a mean duration of ten days." | 2.66 | [Efficacy of injectable ofloxacin in treating septicemia. Multicenter study]. ( Doco-Lecompte, T; Modaï, J, 1989) |
| "Ofloxacin was radiolabeled with (99m) Tc using carbonyl core." | 1.39 | (99m) Tc-tricabonyl labeling of ofloxacin and its biological evaluation in Staphylococcus aureus as an infection imaging agent. ( Andishmand, A; Doroudi, A; Erfani, M; Hadisi, L; Mirshojaei, SF; Shafiei, M, 2013) |
| "We studied the pharmacokinetic and pharmacodynamic parameters of levofloxacin and rifampicin in bone and joint infections." | 1.38 | Pharmacokinetic and dynamic study of levofloxacin and rifampicin in bone and joint infections. ( Bensalem, M; Bland, S; Bru, JP; Gaillat, J; Garraffo, R; Guillaume, M; Janssen, C, 2012) |
| "Levofloxacin seems to be a good alternative treatment for patients with uncomplicated spontaneous ascites infections." | 1.36 | A recent evaluation of empirical cephalosporin treatment and antibiotic resistance of changing bacterial profiles in spontaneous bacterial peritonitis. ( Alişkan, H; Güçlü, M; Husamettin, E; Serin, E; Yakar, T, 2010) |
| "Levofloxacin 1." | 1.36 | Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models. ( Gordon, YJ; Kowalski, RP; Mah, FS; Romanowski, EG; Shanks, RM, 2010) |
| "Antofloxacin hydrochloride is a new fluoroquinolone antibiotic with broad-spectrum in vitro activity." | 1.35 | Pharmacokinetics/pharmacodynamics of antofloxacin hydrochloride in a neutropenic murine thigh model of Staphylococcus aureus infection. ( Xiao, XM; Xiao, YH, 2008) |
| "Levofloxacin was more efficient than cloxacillin (P < 0." | 1.35 | Intracellular antimicrobial activity appearing as a relevant factor in antibiotic efficacy against an experimental foreign-body infection caused by Staphylococcus aureus. ( Ariza, J; Cabellos, C; Cabo, J; Carreras, M; Euba, G; Gudiol, F; Murillo, O; Pachón, ME; Verdaguer, R, 2009) |
| " The efficacy of the rifampin-levofloxacin combination is not significantly improved by the dosage of levofloxacin." | 1.35 | Antagonistic effect of rifampin on the efficacy of high-dose levofloxacin in staphylococcal experimental foreign-body infection. ( Ariza, J; Cabellos, C; Cabo, J; Euba, G; Gudiol, F; Murillo, O; Pachón, ME; Tubau, F; Verdaguer, R, 2008) |
| "Levofloxacin treatment had no effect on IL-6 activities and concentrations in uninfected broilers." | 1.34 | Role of interleukin-6 in the pathogenesis of an avian model of Staphylococcus aureus arthritis. ( Cheng, GF; Gu, CQ; Hu, XY; Li, XM; Wang, DH; Zhou, Q; Zhou, SQ, 2007) |
| "A correlation was seen between both the area under the serum concentration curve and MIC (AUC/MIC) and the peak concentration/MIC (Cmax/MIC) versus area under the bactericidal killing curve (AUBKC) or Deltalog0-24 cfu/mL." | 1.33 | Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model. ( Cars, O; Odenholt, I, 2006) |
| " Efforts should be directed at modifying hospital policies for dosing of levofloxacin and DTCCs to prevent coadministration." | 1.33 | Coadministration of oral levofloxacin with agents that impair its absorption: potential impact on emergence of resistance. ( Barton, TD; Fishman, NO; Lautenbach, E; Quain, RD; Weiner, MG, 2005) |
| "The objective of this paper was to investigate the in vitro effects of linezolid combined with five antistaphylococcal antibiotics--doxycycline, fosfomycin, levofloxacin, rifampicin and vancomycin--upon methicillin-susceptible Staphylococcus aureus (MSSA)." | 1.33 | In vitro activity of linezolid in combination with doxycycline, fosfomycin, levofloxacin, rifampicin and vancomycin against methicillin-susceptible Staphylococcus aureus. ( Cantón, E; Colombo Gainza, E; Gil Brusola, A; Gobernado, M; Ortiz Estévez, R; Sahuquillo Arce, JM, 2006) |
| "The mutant selection window hypothesis, originally based on agar plate assays, may lead to new antimicrobial dosing strategies that severely restrict the acquisition of resistance." | 1.33 | The mutant selection window in rabbits infected with Staphylococcus aureus. ( Cui, J; Drlica, K; Liu, Y; Tong, W; Wang, R; Zhao, X, 2006) |
| "A rat model was used to investigate the efficacy of linezolid, alone or in combination with levofloxacin and vancomycin, in the prevention of vascular prosthetic graft infection resulting from methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides." | 1.32 | Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides. ( Cirioni, O; D'Amato, G; Del Prete, MS; Ghiselli, R; Giacometti, A; Mocchegiani, F; Orlando, F; Saba, V; Scalise, G; Silvestri, C, 2003) |
| "Bacterial keratitis is a serious infectious ocular disease requiring prompt treatment to prevent frequent and severe visual disabilities." | 1.32 | A mucoadhesive polymer extracted from tamarind seed improves the intraocular penetration and efficacy of rufloxacin in topical treatment of experimental bacterial keratitis. ( Boldrini, E; Campa, M; Celandroni, F; Davini, P; Ghelardi, E; Parisio, E; Salvetti, S; Senesi, S; Tavanti, A, 2004) |
| "We report a case of lumbar discitis caused by Staphylococcus lugdunensis in a 67-year-old man receiving chemotherapy for stage III IgA lambda multiple myeloma." | 1.31 | Three-year outcome in a patient with Staphylococcus lugdunensis discitis. ( Camacho, M; Costello, R; Guis, S; Mattei, JP; Roudier, J, 2002) |
| " Only the group treated with quinupristin/dalfopristin combined with levofloxacin or doxycycline showed no evidence of staphylococcal infection." | 1.31 | Quinupristin/dalfopristin bonding in combination with intraperitoneal antibiotics prevent infection of knitted polyester graft material in a subcutaneous rat pouch model infected with resistant Staphylococcus epidermidis. ( Cirioni, O; D'Amato, G; Del Prete, M; Ghiselli, R; Giacometti, A; Mocchegiani, F; Orlando, F; Saba, V; Scalise, G, 2002) |
| "Oral therapy of staphylococcal infection of orthopaedic implants with 900 mg/day rifampicin combined with either 1." | 1.30 | Oral treatment of Staphylococcus spp. infected orthopaedic implants with fusidic acid or ofloxacin in combination with rifampicin. ( Argenson, JN; Drancourt, M; Groulier, P; Raoult, D; Roiron, R; Stein, A, 1997) |
| "Levofloxacin was the most potent fluoroquinolone against both strains and its activity was not significantly affected by combination with omeprazole." | 1.30 | The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model. ( Aeschlimann, JR; Kaatz, GW; Rybak, MJ, 1999) |
| "Levofloxacin was no more effective than penicillin against the penicillin-resistant strain." | 1.30 | Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus. ( Chambers, HF; Chow, LL; Hackbarth, C; Xiang, Q, 1999) |
| "Vancomycin was the most effective prophylactic agent, exhibiting in vivo activity against all strains which was superior or equivalent to those of all other agents tested." | 1.29 | Comparative prophylactic efficacies of ciprofloxacin, ofloxacin, cefazolin, and vancomycin in experimental model of staphylococcal wound infection. ( Kaiser, AB; Kernodle, DS, 1994) |
| " The largest reductions of viable counts in the kidneys at each dosage as compared to the bacterial counts of untreated animals were achieved with coumermycin (3." | 1.27 | Efficacy of coumermycin, ofloxacin and vancomycin against methicillin-resistant Staphylococcus aureus in vitro and in experimental infections of mice. ( Breyer, S; Georgopoulos, A; Hirschl, AM; Rotter, ML; Stanek, G, 1988) |
| "Ofloxacin was active against all but one (Pseudomonas aeruginosa) blood culture isolates." | 1.27 | Comparative activity of ofloxacin with reference to bacterial strains isolated in in-patients and out-patients. ( Alkan, M; Berger, S; Bogokowski, B; Keren, G; Mark, Z; Rubinstein, E, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (6.96) | 18.7374 |
| 1990's | 48 (30.38) | 18.2507 |
| 2000's | 69 (43.67) | 29.6817 |
| 2010's | 28 (17.72) | 24.3611 |
| 2020's | 2 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Jinbo, Y | 2 |
| Kondo, H | 2 |
| Taguchi, M | 2 |
| Inoue, Y | 3 |
| Sakamoto, F | 2 |
| Tsukamoto, G | 2 |
| Higashide, M | 1 |
| Kuroda, M | 1 |
| Omura, CT | 1 |
| Kumano, M | 1 |
| Ohkawa, S | 1 |
| Ichimura, S | 1 |
| Ohta, T | 1 |
| Cormier, R | 1 |
| Burda, WN | 1 |
| Harrington, L | 1 |
| Edlinger, J | 1 |
| Kodigepalli, KM | 1 |
| Thomas, J | 1 |
| Kapolka, R | 1 |
| Roma, G | 1 |
| Anderson, BE | 1 |
| Turos, E | 1 |
| Shaw, LN | 1 |
| Bhawsar, S | 1 |
| Joshi, S | 1 |
| Deshpande, P | 1 |
| Yeole, R | 1 |
| Bhagwat, S | 1 |
| Patel, M | 1 |
| Sivaraman, GK | 1 |
| Gupta, SS | 1 |
| Visnuvinayagam, S | 1 |
| Muthulakshmi, T | 1 |
| Elangovan, R | 1 |
| Perumal, V | 1 |
| Balasubramanium, G | 1 |
| Lodha, T | 1 |
| Yadav, A | 1 |
| Dey, S | 2 |
| Bishayi, B | 2 |
| Maderuelo Riesco, I | 1 |
| Tarrazo Tarrazo, C | 1 |
| Martínez García, P | 1 |
| Rasamiravaka, T | 1 |
| Rasoanandrasana, S | 1 |
| Zafindraibe, NJ | 1 |
| Rakoto Alson, AO | 1 |
| Rasamindrakotroka, A | 1 |
| Erfani, M | 1 |
| Doroudi, A | 1 |
| Hadisi, L | 1 |
| Andishmand, A | 1 |
| Mirshojaei, SF | 1 |
| Shafiei, M | 1 |
| Berlutti, F | 1 |
| Frioni, A | 1 |
| Natalizi, T | 1 |
| Pantanella, F | 1 |
| Valenti, P | 1 |
| Dubos, M | 1 |
| Barraud, O | 1 |
| Fedou, AL | 1 |
| Fredon, F | 1 |
| Laurent, F | 1 |
| Brakbi, Y | 1 |
| Cypierre, A | 1 |
| François, B | 1 |
| Rasool, MH | 1 |
| Siddique, AB | 1 |
| Saqalein, M | 1 |
| Asghar, MJ | 1 |
| Zahoor, MA | 1 |
| Aslam, B | 1 |
| Shafiq, HB | 1 |
| Nisar, MA | 1 |
| Mikhail, M | 1 |
| Koenekoop, RK | 1 |
| Khan, A | 2 |
| Ullah, O | 1 |
| Ambreen, A | 1 |
| Ahmad, I | 1 |
| Akhtar, T | 1 |
| Gandapor, AJ | 1 |
| Khan, AM | 1 |
| Barberán, J | 2 |
| Aguilar, L | 2 |
| Giménez, MJ | 2 |
| Carroquino, G | 2 |
| Granizo, JJ | 1 |
| Prieto, J | 2 |
| Videler, WJ | 1 |
| van Drunen, CM | 1 |
| Reitsma, JB | 1 |
| Fokkens, WJ | 1 |
| Murillo, O | 4 |
| Pachón, ME | 3 |
| Euba, G | 3 |
| Verdaguer, R | 3 |
| Tubau, F | 3 |
| Cabellos, C | 4 |
| Cabo, J | 3 |
| Gudiol, F | 4 |
| Ariza, J | 4 |
| El Samad, Y | 1 |
| Havet, E | 1 |
| Bentayeb, H | 1 |
| Olory, B | 1 |
| Canarelli, B | 1 |
| Lardanchet, JF | 1 |
| Douadi, Y | 1 |
| Rousseau, F | 1 |
| Lescure, FX | 1 |
| Mertl, P | 1 |
| Eb, F | 1 |
| Schmit, JL | 1 |
| Xiao, XM | 1 |
| Xiao, YH | 1 |
| Brousse, C | 1 |
| Montigny, JP | 1 |
| Marroun, I | 1 |
| Garreau de Loubresse, C | 1 |
| Kahn, JE | 1 |
| Muller-Serieys, C | 1 |
| Saleh Mghir, A | 1 |
| Massias, L | 1 |
| Fantin, B | 1 |
| Tattevin, P | 1 |
| Basuino, L | 1 |
| Chambers, HF | 2 |
| Yakar, T | 1 |
| Güçlü, M | 1 |
| Serin, E | 1 |
| Alişkan, H | 1 |
| Husamettin, E | 1 |
| Vignaroli, C | 1 |
| Carreras, M | 1 |
| Chee, E | 1 |
| Looi, A | 1 |
| Hart, E | 1 |
| Azzopardi, K | 1 |
| Taing, H | 1 |
| Graichen, F | 1 |
| Jeffery, J | 1 |
| Mayadunne, R | 1 |
| Wickramaratna, M | 1 |
| O'Shea, M | 1 |
| Nijagal, B | 1 |
| Watkinson, R | 1 |
| O'Leary, S | 1 |
| Finnin, B | 1 |
| Tait, R | 1 |
| Robins-Browne, R | 1 |
| Kowalski, RP | 1 |
| Romanowski, EG | 1 |
| Mah, FS | 1 |
| Shanks, RM | 1 |
| Gordon, YJ | 1 |
| Wu, XG | 1 |
| Xin, M | 1 |
| Chen, H | 2 |
| Yang, LN | 1 |
| Jiang, HR | 1 |
| Fernández-Ruiz, M | 1 |
| Cervera, C | 1 |
| Pitart, C | 1 |
| Pérez, G | 1 |
| del Río, A | 1 |
| Miró, JM | 1 |
| Marco, F | 1 |
| Moreno, A | 1 |
| Kim, SJ | 1 |
| Toma, HS | 1 |
| Wagenlehner, F | 1 |
| Roscher, K | 1 |
| Naber, KG | 1 |
| Shi, G | 1 |
| Chen, X | 1 |
| Wang, H | 1 |
| Wang, S | 1 |
| Guo, X | 1 |
| Zhang, X | 1 |
| Wu, X | 1 |
| Jiang, H | 1 |
| Xu, Y | 1 |
| Yue, W | 1 |
| Yang, L | 1 |
| Song, Z | 1 |
| Liu, T | 1 |
| Gomes, F | 1 |
| Teixeira, P | 1 |
| Ceri, H | 1 |
| Oliveira, R | 1 |
| Jamal, T | 1 |
| Rahman, MA | 1 |
| Mirza, MA | 1 |
| Panda, AK | 1 |
| Talegaonkar, S | 1 |
| Iqbal, Z | 1 |
| Hafezi, F | 1 |
| Zhang, ZC | 1 |
| Jin, FS | 1 |
| Liu, DM | 1 |
| Shen, ZJ | 1 |
| Sun, YH | 1 |
| Guo, YL | 1 |
| Guillaume, M | 1 |
| Garraffo, R | 3 |
| Bensalem, M | 1 |
| Janssen, C | 1 |
| Bland, S | 1 |
| Gaillat, J | 1 |
| Bru, JP | 1 |
| Paleiron, N | 1 |
| Nguyen, BV | 1 |
| Commandeur, D | 1 |
| Danguy des Déserts, M | 1 |
| Rioualen, S | 1 |
| Ralec, B | 1 |
| André, M | 1 |
| Ould-Ahmed, M | 1 |
| Rousset, J | 1 |
| Wang, T | 1 |
| Huang, X | 1 |
| Gao, Q | 1 |
| Feng, L | 1 |
| Xie, Z | 1 |
| Jiang, Z | 1 |
| Liu, Y | 2 |
| Li, Y | 1 |
| Lin, X | 1 |
| Lin, J | 1 |
| Taha, AB | 1 |
| Ghiselli, R | 4 |
| Giacometti, A | 4 |
| Cirioni, O | 4 |
| Mocchegiani, F | 4 |
| Orlando, F | 2 |
| Del Prete, M | 1 |
| D'Amato, G | 2 |
| Scalise, G | 4 |
| Saba, V | 4 |
| Sotozono, C | 1 |
| Inagaki, K | 1 |
| Fujita, A | 1 |
| Koizumi, N | 1 |
| Sano, Y | 1 |
| Inatomi, T | 1 |
| Kinoshita, S | 1 |
| Trinchieri, A | 1 |
| Marchetti, F | 1 |
| Tungsiripat, T | 1 |
| Sarayba, MA | 1 |
| Kaufman, MB | 1 |
| Sweet, PM | 1 |
| Taban, M | 1 |
| Carpenter, TR | 1 |
| McDonnell, PJ | 2 |
| Solomon, R | 2 |
| Donnenfeld, ED | 2 |
| Perry, HD | 2 |
| Biser, S | 1 |
| Del Prete, MS | 1 |
| Silvestri, C | 1 |
| Matoba, AY | 1 |
| Zeitlinger, MA | 1 |
| Dehghanyar, P | 1 |
| Mayer, BX | 1 |
| Schenk, BS | 1 |
| Neckel, U | 1 |
| Heinz, G | 1 |
| Georgopoulos, A | 2 |
| Müller, M | 1 |
| Joukhadar, C | 1 |
| Entenza, JM | 2 |
| Vouillamoz, J | 2 |
| Glauser, MP | 2 |
| Moreillon, P | 2 |
| Tenover, FC | 1 |
| Weigel, LM | 1 |
| Appelbaum, PC | 1 |
| McDougal, LK | 1 |
| Chaitram, J | 1 |
| McAllister, S | 1 |
| Clark, N | 1 |
| Killgore, G | 1 |
| O'Hara, CM | 1 |
| Jevitt, L | 1 |
| Patel, JB | 1 |
| Bozdogan, B | 1 |
| Barequet, IS | 1 |
| Denton, P | 1 |
| Osterhout, GJ | 1 |
| Tuli, S | 1 |
| O'Brien, TP | 1 |
| Marangon, FB | 1 |
| Miller, D | 1 |
| Muallem, MS | 1 |
| Romano, AC | 1 |
| Alfonso, EC | 1 |
| Dajcs, JJ | 3 |
| Thibodeaux, BA | 3 |
| Marquart, ME | 2 |
| Girgis, DO | 2 |
| Traidej, M | 2 |
| O'Callaghan, RJ | 4 |
| Ghelardi, E | 1 |
| Tavanti, A | 1 |
| Davini, P | 1 |
| Celandroni, F | 1 |
| Salvetti, S | 1 |
| Parisio, E | 1 |
| Boldrini, E | 1 |
| Senesi, S | 1 |
| Campa, M | 1 |
| Oguz, H | 2 |
| Ozbilge, H | 1 |
| Oguz, E | 1 |
| Gurkan, T | 1 |
| Arnold, FW | 1 |
| Wojda, B | 1 |
| Gehanno, P | 1 |
| Pessey, JJ | 1 |
| Serrano, E | 1 |
| Quain, RD | 1 |
| Barton, TD | 1 |
| Fishman, NO | 1 |
| Weiner, MG | 1 |
| Lautenbach, E | 1 |
| Turgut, H | 1 |
| Sacar, S | 1 |
| Kaleli, I | 1 |
| Sacar, M | 1 |
| Goksin, I | 1 |
| Toprak, S | 1 |
| Asan, A | 1 |
| Cevahir, N | 1 |
| Tekin, K | 1 |
| Baltalarli, A | 1 |
| Ruotsalainen, E | 2 |
| Järvinen, A | 2 |
| Koivula, I | 1 |
| Kauma, H | 1 |
| Rintala, E | 1 |
| Lumio, J | 1 |
| Kotilainen, P | 1 |
| Vaara, M | 1 |
| Nikoskelainen, J | 1 |
| Valtonen, V | 2 |
| Ramdani-Bouguessa, N | 1 |
| Bes, M | 1 |
| Meugnier, H | 1 |
| Forey, F | 1 |
| Reverdy, ME | 1 |
| Lina, G | 1 |
| Vandenesch, F | 1 |
| Tazir, M | 1 |
| Etienne, J | 1 |
| Yağci, R | 1 |
| Oflu, Y | 1 |
| Dinçel, A | 1 |
| Kaya, E | 1 |
| Yağci, S | 1 |
| Bayar, B | 1 |
| Duman, S | 1 |
| Bozkurt, A | 3 |
| Mecikoglu, M | 1 |
| Saygi, B | 1 |
| Yildirim, Y | 1 |
| Karadag-Saygi, E | 1 |
| Ramadan, SS | 1 |
| Esemenli, T | 1 |
| Fukaya, Y | 1 |
| Kurita, A | 1 |
| Tsuruga, H | 1 |
| Naito, A | 1 |
| Nakaya, S | 1 |
| Sato, M | 2 |
| Kamata, Y | 1 |
| Hirata, H | 1 |
| Kambara, Y | 1 |
| Kurasawa, N | 1 |
| Wada, T | 2 |
| Toyoda, Y | 1 |
| Shirasawa, E | 1 |
| Ohashi, Y | 1 |
| Odenholt, I | 1 |
| Cars, O | 1 |
| Doménech, A | 1 |
| Garcia, A | 1 |
| Sánchez, B | 1 |
| Martínez, D | 1 |
| Cui, J | 1 |
| Wang, R | 1 |
| Tong, W | 1 |
| Drlica, K | 2 |
| Zhao, X | 2 |
| Sahuquillo Arce, JM | 1 |
| Colombo Gainza, E | 1 |
| Gil Brusola, A | 1 |
| Ortiz Estévez, R | 1 |
| Cantón, E | 1 |
| Gobernado, M | 1 |
| Rubinfeld, RS | 1 |
| Ehrenhaus, M | 1 |
| Wittpenn, JR | 1 |
| Solomon, KD | 1 |
| Manche, EE | 1 |
| Moshirfar, M | 1 |
| Matzkin, DC | 1 |
| Mozayeni, RM | 1 |
| Maloney, RK | 1 |
| Nguyen, HA | 1 |
| Grellet, J | 1 |
| Dubois, V | 1 |
| Saux, MC | 1 |
| Quentin, C | 1 |
| Zhou, Q | 1 |
| Gu, CQ | 1 |
| Hu, XY | 1 |
| Wang, DH | 1 |
| Li, XM | 1 |
| Zhou, SQ | 1 |
| Cheng, GF | 1 |
| Trampuz, A | 2 |
| Murphy, CK | 1 |
| Rothstein, DM | 1 |
| Widmer, AF | 1 |
| Landmann, R | 1 |
| Zimmerli, W | 2 |
| Foo, SS | 1 |
| Lye, DC | 1 |
| Drago, L | 1 |
| De Vecchi, E | 1 |
| Nicola, L | 1 |
| Gismondo, MR | 1 |
| Liskova, A | 1 |
| Benca, J | 1 |
| Kalavsky, E | 1 |
| Kovac, M | 1 |
| Rudinsky, B | 1 |
| Ondrusova, A | 1 |
| Kiwou, M | 1 |
| Ferrer, C | 1 |
| Rodríguez, A | 1 |
| Abad, JL | 1 |
| Fernandez, J | 1 |
| Alió, JL | 1 |
| Kida, T | 1 |
| Inoue, T | 1 |
| Tokushige, H | 1 |
| Naka, H | 1 |
| Sakaki, H | 1 |
| Kardén-Lilja, M | 1 |
| Kuusela, P | 1 |
| Vuopio-Varkila, J | 1 |
| Virolainen-Julkunen, A | 1 |
| Sarna, S | 1 |
| Lin, B | 1 |
| Su, X | 1 |
| Hori, S | 1 |
| Ohshita, Y | 1 |
| Utsui, Y | 1 |
| Hiramatsu, K | 1 |
| Sesso, R | 1 |
| Parisio, K | 1 |
| Dalboni, A | 1 |
| Rabelo, T | 1 |
| Barbosa, D | 1 |
| Cendoroglo, M | 1 |
| Pignatari, A | 1 |
| Draibe, S | 1 |
| Ajzen, H | 1 |
| Kernodle, DS | 1 |
| Kaiser, AB | 1 |
| Drancourt, M | 2 |
| Stein, A | 2 |
| Argenson, JN | 2 |
| Zannier, A | 1 |
| Curvale, G | 1 |
| Raoult, D | 2 |
| Gentry, LO | 2 |
| Rodriguez-Gomez, G | 1 |
| Khardori, N | 1 |
| Yassien, M | 1 |
| Wilson, K | 1 |
| Bow, EJ | 1 |
| Mandell, LA | 1 |
| Louie, TJ | 1 |
| Feld, R | 1 |
| Palmer, M | 1 |
| Zee, B | 1 |
| Pater, J | 1 |
| Tong, MC | 1 |
| Woo, JK | 1 |
| van Hasselt, CA | 1 |
| Frosco, MB | 1 |
| Melton, JL | 1 |
| Stewart, FP | 1 |
| Kulwich, BA | 1 |
| Licata, L | 1 |
| Barrett, JF | 1 |
| Roiron, R | 1 |
| Groulier, P | 1 |
| Bamberger, DM | 1 |
| Herndon, BL | 1 |
| Dew, M | 1 |
| Chern, RP | 1 |
| Mitchell, H | 1 |
| Summers, LE | 1 |
| Marcus, RF | 1 |
| Kim, SC | 1 |
| Suvarna, PR | 1 |
| Watanabe, H | 1 |
| Sato, S | 1 |
| Maeda, N | 1 |
| Shimomura, Y | 1 |
| Tano, Y | 1 |
| Ceviz, A | 1 |
| Inalöz, SS | 1 |
| Ciçek, R | 1 |
| Sari, I | 1 |
| Gül, K | 1 |
| Sanli, A | 1 |
| Nicolau, DP | 1 |
| Nie, L | 1 |
| Tessier, PR | 1 |
| Kourea, HP | 1 |
| Nightingale, CH | 1 |
| Nicodemo, AC | 1 |
| Robledo, JA | 1 |
| Jasovich, A | 1 |
| Neto, W | 1 |
| DeAbate, CA | 1 |
| Henry, D | 1 |
| Bensch, G | 1 |
| Jubran, A | 1 |
| Chodosh, S | 1 |
| Harper, L | 1 |
| Tipping, D | 1 |
| Talbot, GH | 1 |
| Colsky, AS | 1 |
| Kirsner, RS | 1 |
| Kerdel, FA | 1 |
| Moreau, JM | 3 |
| Green, LC | 1 |
| Engel, LS | 1 |
| Hill, JM | 1 |
| Le Thi Huong, D | 1 |
| Cassoux, N | 1 |
| Kemali, Z | 1 |
| Wechsler, B | 1 |
| Blétry, O | 1 |
| Le Hoang, P | 1 |
| Piette, JC | 1 |
| Schumacher-Perdreau, F | 1 |
| Peters, G | 1 |
| Krutikov, MG | 1 |
| Alekseev, AA | 1 |
| Bobrovnikov, AE | 1 |
| Grishina, IA | 1 |
| Elagina, LV | 1 |
| Izotova, GN | 1 |
| Iakovlev, VP | 1 |
| Akiyama, H | 2 |
| Yamasaki, O | 1 |
| Kanzaki, H | 2 |
| Tada, J | 1 |
| Arata, J | 2 |
| Tabe, Y | 1 |
| Nakamura, A | 1 |
| Oguri, T | 1 |
| Igari, J | 1 |
| Prenna, M | 1 |
| Montanari, MP | 1 |
| Mingoia, M | 1 |
| Biavasco, F | 1 |
| Ripa, S | 1 |
| Varaldo, PE | 1 |
| Aeschlimann, JR | 2 |
| Dresser, LD | 1 |
| Kaatz, GW | 3 |
| Rybak, MJ | 3 |
| Osada, T | 1 |
| Yamamura, K | 1 |
| Fujimoto, K | 1 |
| Mizuno, K | 1 |
| Sakurai, T | 1 |
| Ohta, M | 1 |
| Nabeshima, T | 1 |
| Fukuda, M | 1 |
| Inoue, A | 1 |
| Sasaki, K | 1 |
| Oztürk, F | 2 |
| Kortunay, S | 2 |
| Kurt, E | 2 |
| Ubeyt Inan, U | 1 |
| Sami Ilker, S | 1 |
| Basci, NE | 1 |
| Oguz Kayaalp, S | 1 |
| Xiang, Q | 1 |
| Chow, LL | 1 |
| Hackbarth, C | 1 |
| Inan, UU | 1 |
| Ilker, SS | 1 |
| Basci, N | 1 |
| Panda, A | 1 |
| Ahuja, R | 1 |
| Sastry, SS | 1 |
| Wenk, M | 1 |
| Rajacic, Z | 1 |
| Melki, SA | 1 |
| Safar, A | 1 |
| Yaghouti, F | 1 |
| Scharper, P | 1 |
| Scharper, M | 1 |
| Zeligs, B | 1 |
| MacDowell, AL | 1 |
| Goldberg, MA | 1 |
| Lustbader, J | 1 |
| Rao, SN | 1 |
| Fong, Y | 1 |
| Kampmeier, J | 1 |
| LaBree, LD | 1 |
| Tanzer, DJ | 1 |
| Snyder-Perlmutter, LS | 1 |
| Katz, HR | 1 |
| Melia, M | 1 |
| Ortega, M | 1 |
| Soriano, A | 1 |
| García, S | 1 |
| Almela, M | 1 |
| Alvárez, JL | 1 |
| Tomás, X | 1 |
| Mensa, J | 1 |
| Soriano, E | 1 |
| Goffi, L | 1 |
| Boccoli, G | 1 |
| Riva, A | 2 |
| Reid, G | 1 |
| Habash, M | 1 |
| Vachon, D | 1 |
| Denstedt, J | 1 |
| Riddell, J | 1 |
| Beheshti, M | 1 |
| Yoshii, T | 1 |
| Yoshikawa, T | 1 |
| Furudoi, S | 1 |
| Yoshioka, A | 1 |
| Ohtsuka, Y | 1 |
| Komori, T | 1 |
| Shirtliff, ME | 1 |
| Calhoun, JH | 1 |
| Mader, JT | 1 |
| Austin, MS | 1 |
| Stroman, DW | 2 |
| Schlech, BA | 1 |
| Ke, TL | 1 |
| Caballero, AR | 1 |
| Camacho, M | 1 |
| Guis, S | 1 |
| Mattei, JP | 1 |
| Costello, R | 1 |
| Roudier, J | 1 |
| Tillotson, G | 1 |
| Vaudaux, P | 1 |
| Francois, P | 1 |
| Bisognano, C | 1 |
| Schrenzel, J | 1 |
| Lew, DP | 1 |
| Graffunder, EM | 1 |
| Venezia, RA | 1 |
| D'Antonio, D | 1 |
| Pizzigallo, E | 1 |
| Iacone, A | 1 |
| Dell'Isola, M | 1 |
| Fioritoni, G | 1 |
| Betti, S | 1 |
| Piergallini, A | 1 |
| Di Gianfilippo, R | 1 |
| Olioso, P | 1 |
| Torlontano, G | 1 |
| Reynaud, AE | 1 |
| Espaze, EP | 1 |
| Coste-Burel, M | 1 |
| Richet, H | 1 |
| Torigoe, R | 1 |
| Yamada, T | 1 |
| Abe, Y | 1 |
| Shimoe, K | 1 |
| Umemura, S | 1 |
| Katayama, H | 1 |
| Nishihara, O | 1 |
| Yajima, H | 1 |
| Hondou, T | 1 |
| Sugase, M | 1 |
| Eron, LJ | 1 |
| Smith, JT | 1 |
| Barry, AL | 1 |
| Fuchs, PC | 1 |
| Chyrek-Borowska, S | 1 |
| Siergiejko, Z | 1 |
| Jakubicz, P | 1 |
| Dellamonica, P | 2 |
| Drugeon, HB | 1 |
| Etesse, H | 2 |
| Lapalus, P | 1 |
| Sawada, Y | 1 |
| Yotsuyanagi, T | 1 |
| Sone, K | 1 |
| Schalkhäuser, K | 1 |
| Seo, SM | 1 |
| Barriere, SL | 1 |
| Albrecht, LM | 1 |
| Doco-Lecompte, T | 1 |
| Modaï, J | 1 |
| Tronel, H | 1 |
| Voiriot, P | 1 |
| Weber, M | 1 |
| Dopff, C | 1 |
| Dewachter, P | 1 |
| Phelisse, F | 1 |
| Dureux, JB | 1 |
| Shah, PM | 1 |
| Yamaguchi, K | 1 |
| Kawaguchi, K | 1 |
| Chan, MK | 1 |
| Chau, PY | 1 |
| Chan, WW | 1 |
| Hirschl, AM | 1 |
| Stanek, G | 1 |
| Breyer, S | 1 |
| Rotter, ML | 1 |
| Konno, M | 1 |
| Bertrand, A | 1 |
| Janbon, F | 1 |
| Despaux, E | 1 |
| Jonquet, O | 1 |
| Reynes, J | 1 |
| Bernard, E | 1 |
| Giaume, F | 1 |
| Fujimoto, T | 1 |
| Katami, K | 1 |
| Osada, Y | 1 |
| Tsumura, M | 1 |
| Tachizawa, H | 1 |
| Une, T | 1 |
| Rubinstein, E | 1 |
| Mark, Z | 1 |
| Keren, G | 1 |
| Alkan, M | 1 |
| Berger, S | 1 |
| Bogokowski, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Conjunctival Floral Resistance in a Single Practice Site Comparing Povidone- Iodine Prep With or Without Post-Intravitreal Injection Second Generation Fluoroquinolones.[NCT02223338] | 120 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| [NCT00548002] | 430 participants (Actual) | Observational | 1999-01-31 | Completed | |||
| Concentration of Ofloxacin Into the Aqueous Humour of Patients After Topical Instillation According to the Severity of Dry Eye Disease[NCT05213156] | Phase 4 | 91 participants (Actual) | Interventional | 2019-09-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Average number of antibiotics to which isolated organisms were resistant, isolated organisms include only coagulase negative Staphylococcus species and Staphylococcus aureus. Antibiotics are those described in the methods section. (NCT02223338)
Timeframe: Through study completion, average of 4 weeks
| Intervention | antibiotics (Mean) |
|---|---|
| Ciprofloxacin | 5.44 |
| Standard Aseptic Technique | 3.23 |
"Resistance of all coagulase negative staph and staph aureus species to a panel of commonly used antibiotics will be determined and compared between groups. Resistance will be measured using minimum inhibitory concentrations which will be tested on the Siemens MicroScan instrument by doubling broth dilutions. Antibiotic susceptibility interpretations using the categories S for susceptible, I for Intermediate and R for Resistance based on the Clinical and Laboratory Standards Institute (CLSI) guidelines.~Ciprofloxacin will be tested using the Biomerieux E test strip. The test directly quantifies antimicrobial susceptibility in terms of discrete MIC values on a continuous gradient strip. The MIC values are also based on the CLSI guidelines giving interpretations of S, I or R.~For information on other antibiotics to be tested, please contact the investigator or provide more characters for input." (NCT02223338)
Timeframe: Cultured organisms will be subjected to resistance panels once they have grown and been identified. Cultures will be followed for 7 days total, and if no growth is recorded at that time they will be considered sterile.
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 10 |
| Standard Aseptic Technique | 6 |
3 reviews available for ofloxacin and Staphylococcal Infections
| Article | Year |
|---|---|
Fluoroquinolones as pneumococcal therapy: closing the barn door before the horse escapes.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple; Humans; | 2001 |
Ofloxacin, a bactericidal antibacterial.
Topics: Anti-Infective Agents; Bacteria; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Human | 1991 |
[Refractory respiratory tract infections. 6. New problems in refractory respiratory tract infections. c. Chemotherapy of methicillin-resistant Staphylococci infection].
Topics: Anti-Bacterial Agents; Cefmetazole; Cephamycins; Drug Therapy, Combination; Fosfomycin; Humans; Meth | 1987 |
25 trials available for ofloxacin and Staphylococcal Infections
| Article | Year |
|---|---|
Nebulized bacitracin/colimycin: a treatment option in recalcitrant chronic rhinosinusitis with Staphylococcus aureus? A double-blind, randomized, placebo-controlled, cross-over pilot study.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacitracin; Chron | 2008 |
Ophthalmic antibiotics and antimicrobial resistance a randomized, controlled study of patients undergoing intravitreal injections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aza Compounds; Azithromycin; Conjunctiva; Dru | 2011 |
Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients.
Topics: Adult; Anti-Bacterial Agents; Asian People; Ciprofloxacin; Escherichia coli Infections; Humans; Levo | 2012 |
[Multicentric study for evaluation of levofloxacin in the treatment of complicated urinary tract infections].
Topics: Anti-Infective Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Enterobacteriaceae | 2003 |
[Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications].
Topics: Acute Disease; Adolescent; Adult; Africa, Southern; Aged; Bacterial Infections; Female; France; Haem | 2005 |
Levofloxacin does not decrease mortality in Staphylococcus aureus bacteraemia when added to the standard treatment: a prospective and randomized clinical trial of 381 patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Chi-Square Distribution; Drug Therapy, Combination; | 2006 |
Methicillin-sensitive Staphylococcus aureus bacteraemia and endocarditis among injection drug users and nonaddicts: host factors, microbiological and serological characteristics.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Case-Control Studies; Electro | 2008 |
[The clinical observation of China-made ofloxacin eye drops in the treatment of bacterial infection of the external eye].
Topics: Adult; Aged; Conjunctivitis, Bacterial; Hordeolum; Humans; Middle Aged; Ofloxacin; Ophthalmic Soluti | 1994 |
Effect of sodium fusidate and ofloxacin on Staphylococcus aureus colonization and infection in patients on continuous ambulatory peritoneal dialysis.
Topics: Administration, Oral; Administration, Topical; Adult; Catheters, Indwelling; Female; Fusidic Acid; H | 1994 |
Oral rifampin plus ofloxacin for treatment of Staphylococcus-infected orthopedic implants.
Topics: Administration, Oral; Cohort Studies; Drug Therapy, Combination; Hip Prosthesis; Humans; Knee Prosth | 1993 |
Ofloxacin treatment of difficult infections of the skin and skin structure.
Topics: Abscess; Administration, Oral; Adult; Aged; Aged, 80 and over; Cellulitis; Drug Administration Sched | 1993 |
Quinolone-based antibacterial chemoprophylaxis in neutropenic patients: effect of augmented gram-positive activity on infectious morbidity. National Cancer Institute of Canada Clinical Trials Group.
Topics: Adult; Aged; Anti-Infective Agents; Antineoplastic Agents; Bacteremia; Colony Count, Microbial; Fema | 1996 |
A double-blind comparative study of ofloxacin otic drops versus neomycin-polymyxin B-hydrocortisone otic drops in the medical treatment of chronic suppurative otitis media.
Topics: Anti-Infective Agents; Chronic Disease; Double-Blind Method; Drug Combinations; Humans; Hydrocortiso | 1996 |
A multicentre, double-blind, randomised study comparing the efficacy and safety of oral levofloxacin versus ciprofloxacin in the treatment of uncomplicated skin and skin structure infections.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Female; Huma | 1998 |
Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chlamy | 1998 |
[Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns].
Topics: Adolescent; Adult; Anti-Infective Agents; Burns; Drug Resistance, Microbial; Drug Resistance, Multip | 1998 |
Comparison of topical 0.3% ofloxacin with fortified tobramycin plus cefazolin in the treatment of bacterial keratitis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefazolin; Cephalosporins; Co | 1999 |
Effect of topical ciprofloxacin 0.3% and ofloxacin 0.3% on the reduction of bacterial flora on the human conjunctiva.
Topics: Alcaligenes; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Conjunctiva; Conjunctivi | 2000 |
[Tolerability and safety of levofloxacinin long-term treatment].
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Female; Humans; Levofloxacin; | 2000 |
Oral fluoroquinolone therapy results in drug adsorption on ureteral stents and prevention of biofilm formation.
Topics: Administration, Oral; Adsorption; Anti-Infective Agents; Anti-Infective Agents, Urinary; Biofilms; C | 2001 |
Oral ofloxacin for infections caused by bacteria resistant to oral antimicrobial agents.
Topics: Administration, Oral; Adult; Aged; Bacterial Infections; Diabetes Complications; Drug Resistance, Mi | 1992 |
A new approach to optimal antibiotic dosage regimen by coupling pharmacokinetics and killing curve parameters.
Topics: Amikacin; Anti-Bacterial Agents; Cell Survival; Dose-Response Relationship, Drug; Drug Administratio | 1990 |
A silicone gel sheet dressing containing an antimicrobial agent for split thickness donor site wounds.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Collagen; Female; Gels; Humans | 1990 |
Comparison of i.v. ofloxacin and piperacillin in the treatment of complicated urinary tract infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gram-Negative Bacteria; Humans; Injections, Intr | 1990 |
[Efficacy of injectable ofloxacin in treating septicemia. Multicenter study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gram-Negative Bacteria; Humans; Injections, Intr | 1989 |
130 other studies available for ofloxacin and Staphylococcal Infections
| Article | Year |
|---|---|
Synthesis and antibacterial activity of thiazolopyrazine-incorporated tetracyclic quinolone antibacterial agents. 2.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Indica | 1994 |
Synthesis and antibacterial activity of thiazolopyrazine-incorporated tetracyclic quinolone antibacterials.
Topics: Animals; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Methicill | 1994 |
Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections.
Topics: Bacterial Proteins; Chromosomes, Bacterial; Electrophoresis, Gel, Pulsed-Field; Methicillin Resistan | 2008 |
Studies on the antimicrobial properties of N-acylated ciprofloxacins.
Topics: Acylation; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bartonella; Bartonella Infections; | 2012 |
WCK 1152, WCK 1153: Discovery and structure activity relationship for the treatment of resistant pneumococcal and staphylococcal respiratory infections.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Humans; Microbial Sensiti | 2022 |
Prevalence of S. aureus and/or MRSA from seafood products from Indian seafood products.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefoxitin; Gentamicins; Linezolid | 2022 |
Killing of S. aureus in murine peritoneal macrophages by Ascorbic acid along with antibiotics Chloramphenicol or Ofloxacin: Correlation with inflammation.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Chloramphenicol; Cyclooxygenase 2; Cyto | 2018 |
[Herpes zoster ophthalmicus in an immunosuppressed patient].
Topics: Acyclovir; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antiviral Agents; H | 2019 |
Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients.
Topics: Adolescent; Adult; Carrier State; Confidence Intervals; Drug Resistance, Multiple, Bacterial; Erythr | 2013 |
(99m) Tc-tricabonyl labeling of ofloxacin and its biological evaluation in Staphylococcus aureus as an infection imaging agent.
Topics: Animals; Anti-Bacterial Agents; Isotope Labeling; Male; Mice; Mice, Inbred BALB C; Muscle, Skeletal; | 2013 |
Influence of sub-inhibitory antibiotics and flow condition on Staphylococcus aureus ATCC 6538 biofilm development and biofilm growth rate: BioTimer assay as a study model.
Topics: Anti-Bacterial Agents; Azithromycin; Biofilms; Gentamicins; Microbial Sensitivity Tests; Models, The | 2014 |
Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureus producing Panton-Valentine leukocidin.
Topics: Abscess; Bacterial Toxins; Exotoxins; Humans; Leukocidins; Magnetic Resonance Imaging; Male; Methici | 2014 |
Occurrence and antibacterial susceptibility pattern of bacterial pathogens isolated from diarrheal patients in Pakistan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacillus cereus; Cef | 2016 |
Orbital cellulitis and multiple abscess formation after strabismus surgery.
Topics: Abscess; Administration, Topical; Anti-Bacterial Agents; Ceftriaxone; Child, Preschool; Drug Therapy | 2016 |
Antibiotic Sensitivity pattern of Bacterial Isolates of Neonatal Septicemia in Peshawar, Pakistan.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacteri | 2016 |
Effect of iNOS inhibitor LNMMA along with antibiotics Chloramphenicol or Ofloxacin in murine peritoneal macrophages regulates S.aureus infection as well as inflammation: An in vitro study.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Chloramphenicol; Cyclooxygenase 2; Cytokines; Disease | 2017 |
Levofloxacin plus rifampicin conservative treatment of 25 early staphylococcal infections of osteosynthetic devices for rigid internal fixation.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Coagulase; Drug Therapy, Combination; Female; | 2008 |
Antagonistic effect of rifampin on the efficacy of high-dose levofloxacin in staphylococcal experimental foreign-body infection.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Drug Interactions; Forei | 2008 |
[Treatment of osteoarticular infections with clindamycin in adults].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Diseases; Clindamy | 2008 |
Pharmacokinetics/pharmacodynamics of antofloxacin hydrochloride in a neutropenic murine thigh model of Staphylococcus aureus infection.
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred ICR; Mi | 2008 |
[Charcot's disease of the lumbosacral joint in spinal cord injury: a case report].
Topics: Accidents, Traffic; Adult; Arthropathy, Neurogenic; Bacteremia; Diagnostic Errors; Discitis; Epidura | 2008 |
High doses of levofloxacin vs moxifloxacin against staphylococcal experimental foreign-body infection: the effect of higher MIC-related pharmacokinetic parameters on efficacy.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Foreign Bodies; Levofloxacin; Male; | 2009 |
Bactericidal activity of the combination of levofloxacin with rifampin in experimental prosthetic knee infection in rabbits due to methicillin-susceptible Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Therapy, Combination; Humans; Knee Pros | 2009 |
Subinhibitory fluoroquinolone exposure selects for reduced beta-lactam susceptibility in methicillin-resistant Staphylococcus aureus and alterations in the SOS-mediated response.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Ciprofloxacin; Comm | 2009 |
A recent evaluation of empirical cephalosporin treatment and antibiotic resistance of changing bacterial profiles in spontaneous bacterial peritonitis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascitic Fluid; Bacterial Infections; Cefepime | 2010 |
Methicillin-resistant Staphylococcus aureus USA400 Clone, Italy.
Topics: Adult; Anti-Bacterial Agents; California; Female; Humans; Italy; Methicillin Resistance; Methicillin | 2009 |
Intracellular antimicrobial activity appearing as a relevant factor in antibiotic efficacy against an experimental foreign-body infection caused by Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Cloxacillin; Colony Count, Microbial; Cytoplasm; Disease Models, Ani | 2009 |
Onodi sinusitis presenting with orbital apex syndrome.
Topics: Abscess; Anti-Bacterial Agents; Combined Modality Therapy; Drainage; Drug Therapy, Combination; Ethm | 2009 |
Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Female; Foreign Bod | 2010 |
Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Colony Count, Mic | 2010 |
Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis.
Topics: Absorption; Administration, Topical; Animals; Anti-Bacterial Agents; Aqueous Humor; Bacterial Load; | 2010 |
Community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction. Role of antibiotic combination of linezolid plus levofloxacin.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Cerebral Infarction; Community-Acquired Infections; Drug T | 2010 |
[Practice management of chronic bacterial prostatitis with levofloxacin].
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Chronic Disease; Escherichia coli | 2011 |
Activity of sitafloxacin against extracellular and intracellular Staphylococcus aureus in vitro and in vivo: comparison with levofloxacin and moxifloxacin.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Cell Line; Chromatography, High Pressure Liquid; Dise | 2012 |
Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis.
Topics: Animals; Anti-Infective Agents, Local; Colony Count, Microbial; Conjunctival Diseases; Cornea; Eye; | 2012 |
Evaluation of antimicrobial activity of certain combinations of antibiotics against in vitro Staphylococcus epidermidis biofilms.
Topics: Biofilms; Clindamycin; Drug Combinations; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity T | 2012 |
Formulation, antimicrobial and toxicity evaluation of bioceramic based ofloxacin loaded biodegradable microspheres for periodontal infection.
Topics: Animals; Anti-Bacterial Agents; Cell Survival; Chemistry, Pharmaceutical; Escherichia coli; Escheric | 2012 |
Significant visual increase following infectious keratitis after collagen cross-linking.
Topics: Anti-Bacterial Agents; Collagen; Corneal Stroma; Corneal Topography; Corneal Ulcer; Cross-Linking Re | 2012 |
Pharmacokinetic and dynamic study of levofloxacin and rifampicin in bone and joint infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Arthritis, Infectious; Body Mass Index; Discit | 2012 |
[Miliary X-ray pattern is not always related to tuberculosis].
Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Combined Modality Therapy; Device Remov | 2013 |
A preliminary study to treat severe endophthalmitis via a foldable capsular vitreous body with sustained levofloxacin release in rabbits.
Topics: Animals; Anti-Bacterial Agents; Ciliary Body; Colony Count, Microbial; Cytokines; Drug Delivery Syst | 2013 |
Relationship and susceptibility profile of Staphylococcus aureus infection diabetic foot ulcers with Staphylococcus aureus nasal carriage.
Topics: Adult; Aged; Anti-Bacterial Agents; Carrier State; Diabetic Foot; Female; Humans; Levofloxacin; Male | 2013 |
Quinupristin/dalfopristin bonding in combination with intraperitoneal antibiotics prevent infection of knitted polyester graft material in a subcutaneous rat pouch model infected with resistant Staphylococcus epidermidis.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Disease Models, Anima | 2002 |
Methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis infections in the cornea.
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Child; Dibekacin; Eye Infections, Bacterial; Fe | 2002 |
Fluoroquinolone therapy in multiple-drug resistant staphylococcal keratitis after lamellar keratectomy in a rabbit model.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Corneal Stroma; Disease Mode | 2003 |
Bilateral methicillin-resistant staphylococcus aureus keratitis in a medical resident following an uneventful bilateral photorefractive keratectomy.
Topics: Adult; Cornea; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Eyelids; Female; | 2003 |
Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides.
Topics: Acetamides; Animals; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Drug Therapy, Combination; | 2003 |
Polymicrobial keratitis secondary to Burkholderia ambifaria, enterococcus, and staphylococcus aureus in a patient with herpetic stromal keratitis.
Topics: Amikacin; Burkholderia; Burkholderia Infections; Corneal Stroma; Drug Therapy, Combination; Enteroco | 2003 |
Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis.
Topics: Aged; Anti-Infective Agents; Area Under Curve; Blood Proteins; Drug Delivery Systems; Female; Humans | 2003 |
Efficacy of garenoxacin in treatment of experimental endocarditis due to Staphylococcus aureus or viridans group streptococci.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; En | 2004 |
Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Blotting, Southern; Carbon-Oxygen | 2004 |
Treatment of experimental bacterial keratitis with topical trovafloxacin.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Col | 2004 |
Ciprofloxacin and levofloxacin resistance among methicillin-sensitive Staphylococcus aureus isolates from keratitis and conjunctivitis.
Topics: Anti-Infective Agents; Ciprofloxacin; Conjunctivitis, Bacterial; Cross-Sectional Studies; Drug Resis | 2004 |
Effectiveness of ciprofloxacin, levofloxacin, or moxifloxacin for treatment of experimental Staphylococcus aureus keratitis.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Cornea; Drug Resistance, Bacterial; Fl | 2004 |
A mucoadhesive polymer extracted from tamarind seed improves the intraocular penetration and efficacy of rufloxacin in topical treatment of experimental bacterial keratitis.
Topics: Adhesives; Administration, Topical; Animals; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Colon | 2004 |
Effectiveness of topical taurolidine versus ciprofloxacin, ofloxacin, and fortified cefazolin in a rabbit Staphylococcus aureus keratitis model.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Cefazolin; Ciprofloxacin; Colony Cou | 2005 |
An analysis of a community-acquired pathogen in a Kentucky community: methicillin-resistant Staphylococcus aureus.
Topics: Adult; Anti-Bacterial Agents; Cefazolin; Clindamycin; Community-Acquired Infections; Erythromycin; F | 2005 |
Coadministration of oral levofloxacin with agents that impair its absorption: potential impact on emergence of resistance.
Topics: Administration, Oral; Adsorption; Aged; Anti-Bacterial Agents; Case-Control Studies; Cations, Divale | 2005 |
Systemic and local antibiotic prophylaxis in the prevention of Staphylococcus epidermidis graft infection.
Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Blood Vessel Prosthesis; Blood Vessel Prosth | 2005 |
Detection of methicillin-resistant Staphylococcus aureus strains resistant to multiple antibiotics and carrying the Panton-Valentine leukocidin genes in an Algiers hospital.
Topics: Algeria; Alleles; Anti-Bacterial Agents; Bacterial Toxins; Community-Acquired Infections; Drug Resis | 2006 |
Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.
Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Ciprofloxacin; Disease Models, Animal; | 2007 |
The effect of proteolytic enzyme serratiopeptidase in the treatment of experimental implant-related infection.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dru | 2006 |
Antibiotic effects of WP-0405, a thermo-setting ofloxacin gel, on methicillin-resistant Staphylococcus aureus keratitis in rabbits.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Cil | 2006 |
Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Escherichia coli; Escherichia coli | 2006 |
Efficacy of high doses of levofloxacin in experimental foreign-body infection by methicillin-susceptible Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cloxacillin; Disease Models, Anim | 2006 |
Conservative treatment of staphylococcal prosthetic joint infections in elderly patients.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replac | 2006 |
The mutant selection window in rabbits infected with Staphylococcus aureus.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Colony Count, Microbial; Dif | 2006 |
In vitro activity of linezolid in combination with doxycycline, fosfomycin, levofloxacin, rifampicin and vancomycin against methicillin-susceptible Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; En | 2006 |
Cytotoxic effects of the fluoroquinolone ofloxacin on stromal keratocytes.
Topics: Animals; Anti-Infective Agents; Corneal Stroma; Disease Models, Animal; Eye Infections, Bacterial; H | 2007 |
Methicillin-resistant Staphylococcus aureus infectious keratitis following refractive surgery.
Topics: Adult; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Health Personnel | 2007 |
Factors compromising the activity of moxifloxacin against intracellular Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Aza Compounds; Cell Line; Extracellular Space; Fluoroquinolones; Humans; Hydr | 2007 |
Role of interleukin-6 in the pathogenesis of an avian model of Staphylococcus aureus arthritis.
Topics: Animals; Anti-Bacterial Agents; Arthritis, Infectious; Chickens; Disease Models, Animal; Interleukin | 2007 |
Efficacy of a novel rifamycin derivative, ABI-0043, against Staphylococcus aureus in an experimental model of foreign-body infection.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Drug Therapy, Combi | 2007 |
Methicillin-sensitive Staphylococcus aureus tricuspid valve endocarditis with annular abscess cured with oral levofloxacin and rifampicin.
Topics: Abscess; Adult; Anti-Bacterial Agents; Cloxacillin; Endocarditis, Bacterial; Fever; Humans; Levoflox | 2007 |
In vitro evaluation of antibiotics' combinations for empirical therapy of suspected methicillin resistant Staphylococcus aureus severe respiratory infections.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactams; Drug Therapy, Combination; Humans; Levofloxacin; Meth | 2007 |
Antimicrobial susceptibility of cerebrospinal isolates from patients with meningitis.
Topics: Anti-Bacterial Agents; Cefotaxime; Chloramphenicol; Drug Resistance, Microbial; Haemophilus Infectio | 2007 |
Bactericidal effect of intravitreal levofloxacin in an experimental model of endophthalmitis.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Endophthalmitis; Female; Levofloxacin; Male; Microbial | 2008 |
Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis.
Topics: Animals; Anti-Inflammatory Agents; Aza Compounds; Cells, Cultured; Conjunctivitis; Endotoxins; Fluor | 2008 |
Sequential acquisition of norfloxacin and ofloxacin resistance by methicillin-resistant and -susceptible Staphylococcus aureus.
Topics: Base Sequence; Humans; Japan; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequenc | 1993 |
Comparative prophylactic efficacies of ciprofloxacin, ofloxacin, cefazolin, and vancomycin in experimental model of staphylococcal wound infection.
Topics: Animals; Cefazolin; Ciprofloxacin; Drug Resistance, Microbial; Female; Guinea Pigs; Male; Ofloxacin; | 1994 |
Tolerance of Staphylococcus epidermidis grown from indwelling vascular catheters to antimicrobial agents.
Topics: Anti-Bacterial Agents; Biofilms; Catheters, Indwelling; Drug Resistance, Microbial; Humans; In Vitro | 1995 |
In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains.
Topics: Acute Disease; Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Female; Kidne | 1996 |
Oral treatment of Staphylococcus spp. infected orthopaedic implants with fusidic acid or ofloxacin in combination with rifampicin.
Topics: Administration, Oral; Adult; Aged; Drug Therapy, Combination; Female; Fusidic Acid; Humans; Male; Mi | 1997 |
Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing.
Topics: Abscess; Animals; Anti-Infective Agents; Antibiotics, Antitubercular; Clindamycin; Microbial Sensiti | 1997 |
Levofloxacin versus ciprofloxacin, flucloxacillin, or vancomycin for treatment of experimental endocarditis due to methicillin-susceptible or -resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Endocarditis, Bacterial; Floxa | 1997 |
Bilateral corneal infection as a complication of laser in situ keratomileusis.
Topics: Adolescent; Cilastatin; Cornea; Corneal Diseases; Corneal Transplantation; Drug Therapy, Combination | 1997 |
Effects of nimodipine and ofloxacin on staphylococcal brain abscesses in rats.
Topics: Animals; Anti-Infective Agents; Brain Abscess; Calcium Channel Blockers; Male; Nimodipine; Ofloxacin | 1997 |
Prophylaxis of acute osteomyelitis with absorbable ofloxacin-impregnated beads.
Topics: Absorption; Acute Disease; Animals; Anti-Infective Agents; Bone and Bones; Female; Microspheres; Ofl | 1998 |
Analysis of antibiotic susceptibilities of skin wound flora in hospitalized dermatology patients. The crisis of antibiotic resistance has come to the surface.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Dermatitis; Drug Resistance, Microbial; | 1998 |
Effectiveness of ciprofloxacin-polystyrene sulfonate (PSS), ciprofloxacin and ofloxacin in a Staphylococcus keratitis model.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Disease Models, Anim | 1998 |
[Endogenous infectious endophthalmitis].
Topics: Aged; Amphotericin B; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Endophthalmitis; Fl | 1998 |
In-vitro activity of three fluoroquinolones, cefotaxime and clindamycin against staphylococci.
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Cephalosporins; Ciproflox | 1995 |
Effects of sucrose and silver on Staphylococcus aureus biofilms.
Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Bacterial Adhesion; Biofilms; Blood Coagulation | 1998 |
Molecular characterization of epidemic multiresistant Staphylococcus haemolyticus isolates.
Topics: Ampicillin; Anti-Bacterial Agents; Cefazolin; Cefmetazole; Cross Infection; DNA Restriction Enzymes; | 1998 |
Antistaphylococcal and antistreptococcal killing kinetics of ciprofloxacin, ofloxacin, sparfloxacin, and trovafloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbia | 1998 |
Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus.
Topics: Anti-Infective Agents; Bacterial Proteins; Biological Transport; Ciprofloxacin; Drug Synergism; Huma | 1999 |
Prophylaxis of local vascular graft infection with levofloxacin incorporated into albumin-sealed dacron graft (LVFX-ALB Graft).
Topics: Albumins; Animals; Anti-Infective Agents; Bacterial Adhesion; Blood Vessel Prosthesis Implantation; | 1999 |
[An animal model of corneal bacterial infection induced by intra-corneal injection of Staphylococcus epidermidis].
Topics: Animals; Anti-Infective Agents; Corneal Diseases; Disease Models, Animal; Injections; Ofloxacin; Rab | 1999 |
Ofloxacin levels after intravitreal injection. Effects of trauma and inflammation.
Topics: Animals; Anti-Infective Agents; Endophthalmitis; Eye Injuries; Half-Life; Injections; Ofloxacin; Osm | 1999 |
The effects of NorA inhibition on the activities of levofloxacin, ciprofloxacin and norfloxacin against two genetically related strains of Staphylococcus aureus in an in-vitro infection model.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; Drug Interactions; Drug Resistance, Microb | 1999 |
Efficacy of levofloxacin for experimental aortic-valve endocarditis in rabbits infected with viridans group streptococcus or Staphylococcus aureus.
Topics: Animals; Aortic Valve; Drug Resistance, Microbial; Endocarditis, Bacterial; Heart Valve Diseases; Le | 1999 |
The effect of long-term use and inflammation on the ocular penetration of topical ofloxacin.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Aqueous Humor; Endophthalmitis; Eye; Eye In | 1999 |
Pharmacokinetics and pharmacodynamics of levofloxacin against Streptococcus pneumoniae and Staphylococcus aureus in human skin blister fluid.
Topics: Anti-Infective Agents; Blister; Body Fluids; Granulocytes; Humans; Levofloxacin; Microbial Sensitivi | 2000 |
Effect of topical povidone-iodine versus topical ofloxacin on experimental Staphylococcus keratitis.
Topics: Animals; Anti-Infective Agents; Colony Count, Microbial; Cornea; Disease Models, Animal; Eye Infecti | 2000 |
The effectiveness of a topical antibiotic irrigating solution in a model of staphylococcal keratitis after lamellar keratectomy.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Colony Count, Microbial; Corneal Stroma; Co | 2000 |
Efficacy of rifampin-levofloxacin as a prophylactic agent in preventing Staphylococcus epidermidis graft infection.
Topics: Animals; Blood Vessel Prosthesis; Humans; Levofloxacin; Male; Methicillin Resistance; Microbial Sens | 2000 |
Evaluation of oral antimicrobial agent levels in tooth extraction sites.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alveolar Process; Anti-Bacterial A | 2001 |
Comparative evaluation of oral levofloxacin and parenteral nafcillin in the treatment of experimental methicillin-susceptible Staphylococcus aureus osteomyelitis in rabbits.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Humans; Infusions, Parenteral; Levofloxacin; M | 2001 |
Effectiveness of ciprofloxacin and ofloxacin in a prophylaxis model of Staphylococcus keratitis.
Topics: Animals; Anti-Infective Agents; Antibiotic Prophylaxis; Ciprofloxacin; Colony Count, Microbial; Corn | 2001 |
The effectiveness of tobramycin and Ocuflox in a prophylaxis model of Staphylococcus keratitis.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Colony Count, Microbi | 2001 |
Three-year outcome in a patient with Staphylococcus lugdunensis discitis.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; | 2002 |
Comparison of levofloxacin, alatrofloxacin, and vancomycin for prophylaxis and treatment of experimental foreign-body-associated infection by methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Disease Models, Anima | 2002 |
Risk factors associated with nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection including previous use of antimicrobials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chi-Square Distribution; Confiden | 2002 |
[Vascular graft infection by Staphylococcus epidermidis: efficacy of various perioperative prophylaxis protocols in an animal model].
Topics: Animals; Blood Vessel Prosthesis Implantation; Cefazolin; Drug Evaluation, Preclinical; Drug Implant | 2001 |
Occurrence of bacteremia in hematologic patients.
Topics: Adolescent; Adult; Aged; Bacteremia; Bone Marrow Transplantation; Catheterization; Ciprofloxacin; Fe | 1992 |
[In vitro kinetics of the activity of fusidic acid and fluoroquinolones combinations against staphylococci according to methicillin-resistance phenotype. Implications for the treatment of osteoarticular infections].
Topics: Bone Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fusidic Acid; Humans; In | 1992 |
[Levofloxacin in the field of dermatology].
Topics: Adolescent; Adult; Animals; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Levofloxaci | 1992 |
[Three cases of postpartum infection with methicillin-resistant Staphylococcus aureus (MRSA)].
Topics: Adult; Cefmetazole; Drug Therapy, Combination; Female; Humans; Imipenem; Methicillin Resistance; Min | 1992 |
Anti-staphylococcal activity of temafloxacin, ciprofloxacin, ofloxacin and enoxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Test | 1991 |
[Evaluation of the effectiveness of ofloxacin in the treatment of respiratory tract].
Topics: Administration, Oral; Adult; Aged; Bronchitis; Chronic Disease; Drug Resistance, Microbial; Enteroco | 1991 |
Efficacy of ofloxacin in experimental Staphylococcus aureus endocarditis.
Topics: Animals; Drug Resistance, Microbial; Endocarditis, Bacterial; Female; Methicillin; Microbial Sensiti | 1990 |
[In vivo bactericidal effect of ciprofloxacin, ofloxacin and pefloxacin against Staphylococcus aureus].
Topics: Animals; Ciprofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Rabbits; Staphylococcal | 1989 |
The role of quinolones in staphylococcal infection.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Humans; Norfloxacin; Ofloxacin; Pefloxacin; Staphylo | 1989 |
[Single day treatment in acute cystitis].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Cystitis; | 1988 |
Oral treatment of peritonitis in CAPD patients with ofloxacin.
Topics: Administration, Oral; Adolescent; Adult; Aged; Drug Administration Schedule; Female; Humans; Male; M | 1988 |
Efficacy of coumermycin, ofloxacin and vancomycin against methicillin-resistant Staphylococcus aureus in vitro and in experimental infections of mice.
Topics: Aminocoumarins; Animals; Anti-Bacterial Agents; Coumarins; Drug Resistance, Microbial; Male; Methici | 1988 |
[Ofloxacin (RU 43280). Clinical study].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Therapy, Combination; Enterobacteriaceae Infect | 1987 |
[Bone infections: treatment by ofloxacin. Apropos of 10 cases].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Enterobacteriaceae Infections; | 1987 |
Chemotherapeutic efficacy of ofloxacin on renal and subcutaneous infection models with Staphylococcus aureus in mice.
Topics: Abscess; Animals; Anti-Bacterial Agents; Autoradiography; Disease Models, Animal; Kinetics; Male; Mi | 1986 |
Comparative activity of ofloxacin with reference to bacterial strains isolated in in-patients and out-patients.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cross Infection; Dose-Response Relationship, | 1986 |