Page last updated: 2024-11-01

ofloxacin and Spinal Cord Injuries

ofloxacin has been researched along with Spinal Cord Injuries in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Forty two paraplegic and quadriplegic hospitalized spinal cord injured patients with urinary tract infections (UTI) were included in a double blind, randomized treatment study comparing 7 days ofloxacin (300 mg bd) with trimethoprim-sulphamethoxazole (TMPSMX; 160-800 mg bd) or an alternative, chosen because of resistance to TMPSMX."9.09Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury. ( Delaney, G; Hayes, K; Hsieh, J; Nicosia, S; Potter, P; Reid, G, 2000)
"Forty two paraplegic and quadriplegic hospitalized spinal cord injured patients with urinary tract infections (UTI) were included in a double blind, randomized treatment study comparing 7 days ofloxacin (300 mg bd) with trimethoprim-sulphamethoxazole (TMPSMX; 160-800 mg bd) or an alternative, chosen because of resistance to TMPSMX."5.09Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury. ( Delaney, G; Hayes, K; Hsieh, J; Nicosia, S; Potter, P; Reid, G, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brousse, C1
Montigny, JP1
Marroun, I1
Garreau de Loubresse, C1
Kahn, JE1
Reid, G1
Potter, P1
Delaney, G1
Hsieh, J1
Nicosia, S1
Hayes, K1

Trials

1 trial available for ofloxacin and Spinal Cord Injuries

ArticleYear
Ofloxacin for the treatment of urinary tract infections and biofilms in spinal cord injury.
    International journal of antimicrobial agents, 2000, Volume: 13, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Biofilms; Double-Blin

2000

Other Studies

1 other study available for ofloxacin and Spinal Cord Injuries

ArticleYear
[Charcot's disease of the lumbosacral joint in spinal cord injury: a case report].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2008, Volume: 51, Issue:9

    Topics: Accidents, Traffic; Adult; Arthropathy, Neurogenic; Bacteremia; Diagnostic Errors; Discitis; Epidura

2008