ofloxacin has been researched along with Sleep Initiation and Maintenance Disorders in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study concluded that the dosage regimen of LVFX 500 mg once daily was effective and tolerable for the treatment of LRTIs and UTIs." | 6.74 | Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China. ( Chen, BY; Ding, GH; Duan, J; Gu, JM; Guo, DY; Hao, QL; Huang, HH; Huang, JA; Li, HY; Li, QH; Liu, A; Lü, XJ; Ma, H; Ren, ZY; Shen, HH; Shi, MH; Si, B; Sun, SH; Sun, TY; Wu, GM; Xia, QM; Xiao, W; Xiao, ZK; Xiu, QY; Yang, HF; Yang, HP; Yao, WZ; Ying, KJ; Yu, YS; Yue, HM; Zhang, W; Zhang, YY; Zheng, HG, 2009) |
| " This study concluded that the dosage regimen of LVFX 500 mg once daily was effective and tolerable for the treatment of LRTIs and UTIs." | 2.74 | Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China. ( Chen, BY; Ding, GH; Duan, J; Gu, JM; Guo, DY; Hao, QL; Huang, HH; Huang, JA; Li, HY; Li, QH; Liu, A; Lü, XJ; Ma, H; Ren, ZY; Shen, HH; Shi, MH; Si, B; Sun, SH; Sun, TY; Wu, GM; Xia, QM; Xiao, W; Xiao, ZK; Xiu, QY; Yang, HF; Yang, HP; Yao, WZ; Ying, KJ; Yu, YS; Yue, HM; Zhang, W; Zhang, YY; Zheng, HG, 2009) |
| " In all, 130 adverse reactions have been recorded in 116 patients (5." | 2.66 | Safety profile of ofloxacin: the Italian data base. ( Fostini, R; Granata, F; Koverech, A; Picari, M; Recchia, G; Toniolo, D, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, YY | 1 |
| Huang, HH | 1 |
| Ren, ZY | 1 |
| Zheng, HG | 1 |
| Yu, YS | 1 |
| Lü, XJ | 1 |
| Xiao, ZK | 1 |
| Yang, HF | 1 |
| Xiu, QY | 1 |
| Chen, BY | 1 |
| Yue, HM | 1 |
| Hao, QL | 1 |
| Huang, JA | 1 |
| Ma, H | 1 |
| Xiao, W | 1 |
| Guo, DY | 1 |
| Si, B | 1 |
| Sun, SH | 1 |
| Zhang, W | 1 |
| Li, QH | 1 |
| Shen, HH | 1 |
| Duan, J | 1 |
| Li, HY | 1 |
| Yao, WZ | 1 |
| Gu, JM | 1 |
| Xia, QM | 1 |
| Ying, KJ | 1 |
| Liu, A | 1 |
| Yang, HP | 1 |
| Shi, MH | 1 |
| Sun, TY | 1 |
| Ding, GH | 1 |
| Wu, GM | 1 |
| Yew, WW | 1 |
| Wong, CF | 1 |
| Wong, PC | 1 |
| Lee, J | 1 |
| Chau, CH | 1 |
| Koverech, A | 1 |
| Picari, M | 1 |
| Granata, F | 1 |
| Fostini, R | 1 |
| Toniolo, D | 1 |
| Recchia, G | 1 |
2 trials available for ofloxacin and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China.
Topics: Administration, Oral; Adolescent; Aged; Anti-Bacterial Agents; China; Dizziness; Drug Administration | 2009 |
Safety profile of ofloxacin: the Italian data base.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Clinical Trials as Topic; Drug Eruptions; Female; Ga | 1986 |
1 other study available for ofloxacin and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Adverse neurological reactions in patients with multidrug-resistant pulmonary tuberculosis after coadministration of cycloserine and ofloxacin.
Topics: Adult; Cycloserine; Depression; Drug Therapy, Combination; Humans; Male; Middle Aged; Ofloxacin; Sei | 1993 |