Page last updated: 2024-11-01

ofloxacin and Sinusitis

ofloxacin has been researched along with Sinusitis in 41 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.

Research Excerpts

ExcerptRelevanceReference
"Levofloxacin 750 mg for 5 days represents a safe and effective treatment regimen for acute bacterial sinusitis."9.12A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. ( Anon, J; Kahn, J; Khashab, M; Paglia, M; Poole, M; Xiang, J, 2006)
"Treatment guidelines for acute bacterial rhinosinusitis (ABRS) recommend 10 to 14 days of therapy with high-dose amoxicillin, amoxicillin/clavulanate, cefdinir, cefpodoxime, cefuroxime, a macrolide, or a newer fluoroquinolone, among other agents."9.11Cefdinir versus levofloxacin in patients with acute rhinosinusitis of presumed bacterial etiology: a multicenter, randomized, double-blind study. ( Busman, TA; Henry, DC; Kapral, D; Paris, MM, 2004)
"The authors had for aim to evaluate the efficacy and tolerance of oral levofloxacin (500 mg once a day during ten days), as a treatment for acute bacterial sinusitis at risk for complications in adult patients."9.11[Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications]. ( Gehanno, P; Pessey, JJ; Serrano, E, 2005)
"We previously reported that a 6-month low-dose course of ofloxacin combined with long-term low-dose erythromycin therapy (EM therapy) was superior to EM therapy alone for sinobronchial syndrome (SBS), especially during the initial 2 months of treatment."9.10Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome. ( Fujimura, M; Mizuguchi, M; Mizuhashi, K; Nakatsumi, Y; Sasaki, S; Yasui, M, 2002)
"Levofloxacin is effective for the treatment of sinusitis in adults and pay attention to the course of treatment for raising the efficacy of treatment."9.09[Comparison of the effectiveness of levofloxacin and cefuroxime for the treatment of sinusitis]. ( Li, XP; Qin, ZM; Tan, QL; Yin, AF; Zheng, RH; Zhou, YY; Zhu, L, 2000)
"In this comparative trial, outpatients with acute sinusitis were randomly assigned to receive levofloxacin (500 mg orally once daily) or amoxicillin-clavulanate (500/125 mg orally 3 times daily) for 10 to 14 days."9.09Comparison of the effectiveness of levofloxacin and amoxicillin-clavulanate for the treatment of acute sinusitis in adults. ( Adelglass, J; Campbell, T; DeAbate, CA; Fowler, CL; LoCocco, J; McElvaine, P, 1999)
"It has been established that long-term low-dose erythromycin therapy (EM therapy) is very effective for sinobronchial syndrome, a common condition in Japan characterized by chronic upper and lower airway inflammation."9.08Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. ( Fujimura, M; Ishiura, Y; Matsuda, T; Nakatsumi, Y; Nomura, M; Saito, M; Shibata, K, 1995)
"To evaluate the efficacy and safety of levofloxacin (500 mg orally once daily for 10 to 14 days) in treating adult outpatients with acute bacterial sinusitis."9.08Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults. ( Anthony, KE; Fowler, CL; Kim, SS; Kopp, EJ; LoCoco, JM; Sydnor, TA, 1998)
"Adult patients with acute sinusitis (n = 236) were randomized in a double-blind study to levofloxacin 500 mg orally once daily (n = 119) or clarithromycin 500 mg orally twice daily (n = 117) for 10-14 days."9.08Efficacy and safety of oral levofloxacin compared with clarithromycin in the treatment of acute sinusitis in adults: a multicentre, double-blind, randomized study. The Canadian Sinusitis Study Group. ( Anstey, RJ; Lasko, B; Lau, CY; Martel, A; Reddington, JL; Saint-Pierre, C, 1998)
"A multicentric study was conducted to evaluate the clinical efficacy and tolerance of ofloxacin in the treatment of chronic sinusitis and chronic otitis (CSOM) in outpatients."9.07Effectiveness and safety of ofloxacin in chronic otitis media and chronic sinusitis in adult outpatients. ( Cohen, B; Gehanno, P, 1993)
"The present study compared ofloxacin and erythromycin in a double-blind study with parallel groups for clinical efficacy and the number and severity of adverse reactions in patients treated in general practice for acute or chronic sinusitis."9.07Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. ( Egede, F; Husfeldt, P; Nielsen, PB, 1993)
" The objective is to determine the effect of application of topical ofloxacin on nasal and sinus mucosa in patients with proven existence of bacterial biofilms and persistent chronic sinusitis after FESS."7.81Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis. ( Ezzat, WF; Fawaz, SA; Hamdy, TA; Rabie, H; Shokry, YA, 2015)
"A previous study found that a single 2-g dose of azithromycin extended release (AZ-ER) was as efficacious as 10 days of levofloxacin (LFX) 500 mg QD in adults with acute bacterial rhinosinusitis (ABRS)."7.74Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial. ( de Caprariis, PJ; Marple, BF; Reisman, A; Roberts, CS, 2007)
"The PharMetrics Patient-Centric claims database was searched over a 3-year period for episodes of acute rhinosinusitis treated within 5 days with moxifloxacin or levofloxacin."7.73Moxifloxacin versus levofloxacin for treatment of acute rhinosinusitis: a retrospective database analysis of treatment duration, outcomes, and charges. ( Friedman, HS; Keating, KN; Perfetto, EM, 2006)
"Levofloxacin 750 mg for 5 days represents a safe and effective treatment regimen for acute bacterial sinusitis."5.12A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis. ( Anon, J; Kahn, J; Khashab, M; Paglia, M; Poole, M; Xiang, J, 2006)
"Treatment guidelines for acute bacterial rhinosinusitis (ABRS) recommend 10 to 14 days of therapy with high-dose amoxicillin, amoxicillin/clavulanate, cefdinir, cefpodoxime, cefuroxime, a macrolide, or a newer fluoroquinolone, among other agents."5.11Cefdinir versus levofloxacin in patients with acute rhinosinusitis of presumed bacterial etiology: a multicenter, randomized, double-blind study. ( Busman, TA; Henry, DC; Kapral, D; Paris, MM, 2004)
"The authors had for aim to evaluate the efficacy and tolerance of oral levofloxacin (500 mg once a day during ten days), as a treatment for acute bacterial sinusitis at risk for complications in adult patients."5.11[Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications]. ( Gehanno, P; Pessey, JJ; Serrano, E, 2005)
"We previously reported that a 6-month low-dose course of ofloxacin combined with long-term low-dose erythromycin therapy (EM therapy) was superior to EM therapy alone for sinobronchial syndrome (SBS), especially during the initial 2 months of treatment."5.10Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome. ( Fujimura, M; Mizuguchi, M; Mizuhashi, K; Nakatsumi, Y; Sasaki, S; Yasui, M, 2002)
"Levofloxacin is effective for the treatment of sinusitis in adults and pay attention to the course of treatment for raising the efficacy of treatment."5.09[Comparison of the effectiveness of levofloxacin and cefuroxime for the treatment of sinusitis]. ( Li, XP; Qin, ZM; Tan, QL; Yin, AF; Zheng, RH; Zhou, YY; Zhu, L, 2000)
"In this comparative trial, outpatients with acute sinusitis were randomly assigned to receive levofloxacin (500 mg orally once daily) or amoxicillin-clavulanate (500/125 mg orally 3 times daily) for 10 to 14 days."5.09Comparison of the effectiveness of levofloxacin and amoxicillin-clavulanate for the treatment of acute sinusitis in adults. ( Adelglass, J; Campbell, T; DeAbate, CA; Fowler, CL; LoCocco, J; McElvaine, P, 1999)
"It has been established that long-term low-dose erythromycin therapy (EM therapy) is very effective for sinobronchial syndrome, a common condition in Japan characterized by chronic upper and lower airway inflammation."5.08Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. ( Fujimura, M; Ishiura, Y; Matsuda, T; Nakatsumi, Y; Nomura, M; Saito, M; Shibata, K, 1995)
"To evaluate the efficacy and safety of levofloxacin (500 mg orally once daily for 10 to 14 days) in treating adult outpatients with acute bacterial sinusitis."5.08Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults. ( Anthony, KE; Fowler, CL; Kim, SS; Kopp, EJ; LoCoco, JM; Sydnor, TA, 1998)
"Adult patients with acute sinusitis (n = 236) were randomized in a double-blind study to levofloxacin 500 mg orally once daily (n = 119) or clarithromycin 500 mg orally twice daily (n = 117) for 10-14 days."5.08Efficacy and safety of oral levofloxacin compared with clarithromycin in the treatment of acute sinusitis in adults: a multicentre, double-blind, randomized study. The Canadian Sinusitis Study Group. ( Anstey, RJ; Lasko, B; Lau, CY; Martel, A; Reddington, JL; Saint-Pierre, C, 1998)
"A multicentric study was conducted to evaluate the clinical efficacy and tolerance of ofloxacin in the treatment of chronic sinusitis and chronic otitis (CSOM) in outpatients."5.07Effectiveness and safety of ofloxacin in chronic otitis media and chronic sinusitis in adult outpatients. ( Cohen, B; Gehanno, P, 1993)
"The present study compared ofloxacin and erythromycin in a double-blind study with parallel groups for clinical efficacy and the number and severity of adverse reactions in patients treated in general practice for acute or chronic sinusitis."5.07Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. ( Egede, F; Husfeldt, P; Nielsen, PB, 1993)
"Levofloxacin and sparfloxacin are active against pathogens frequently involved in community-acquired upper and lower respiratory tract infections, including Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Legionella pneumophila, and Chlamydia pneumoniae."4.80Levofloxacin and sparfloxacin: new quinolone antibiotics. ( Chuck, SK; Jung, R; Martin, SJ; Messick, CR; Meyer, JM; Pendland, SL, 1998)
" The objective is to determine the effect of application of topical ofloxacin on nasal and sinus mucosa in patients with proven existence of bacterial biofilms and persistent chronic sinusitis after FESS."3.81Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis. ( Ezzat, WF; Fawaz, SA; Hamdy, TA; Rabie, H; Shokry, YA, 2015)
"Levofloxacin (levogyre form of ofloxacin) has been approved for the treatment of acute and chronic sinusitis, pneumonia, and exacerbation of bronchopulmonary diseases, urinary, digestive and biliary infections in adults."3.76[Levofloxacin in children]. ( Cohen, R; Grimprel, E, 2010)
"A previous study found that a single 2-g dose of azithromycin extended release (AZ-ER) was as efficacious as 10 days of levofloxacin (LFX) 500 mg QD in adults with acute bacterial rhinosinusitis (ABRS)."3.74Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial. ( de Caprariis, PJ; Marple, BF; Reisman, A; Roberts, CS, 2007)
"The PharMetrics Patient-Centric claims database was searched over a 3-year period for episodes of acute rhinosinusitis treated within 5 days with moxifloxacin or levofloxacin."3.73Moxifloxacin versus levofloxacin for treatment of acute rhinosinusitis: a retrospective database analysis of treatment duration, outcomes, and charges. ( Friedman, HS; Keating, KN; Perfetto, EM, 2006)
"Ofloxacin was used at a dosage of 300 mg to 800 mg daily for three to 20 days in 206 cases of various infectious diseases in the otorhinolaryngological field such as otitis media, external otitis, paranasal sinusitis, tonsillitis and pharyngolaryngitis."2.66Clinical efficacy of ofloxacin in the treatment of otorhinolaryngological infections. ( Baba, S, 1986)
"We suspected drug-induced pneumonitis, because her history of fever seemed to be related to drug administration for sinusitis."1.33[A case of drug-induced pneumonitis due to levofloxacin and kampo medicine]. ( Arakaki, N; Shimoji, T; Tamaki, K; Tohyama, M, 2006)
"Sinusitis was induced in six rabbits in order to evaluate its influence on the proliferation of cells in the olfactory epithelium compared with the respiratory epithelium during conservative antibiotic therapy."1.31Uptake of BrdU in olfactory and respiratory epithelium of rabbits with experimental sinusitis. ( Egawa, M; Kurono, Y; Matsune, S; Ohyama, M, 2000)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.44)18.7374
1990's11 (26.83)18.2507
2000's22 (53.66)29.6817
2010's7 (17.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ezzat, WF1
Fawaz, SA1
Rabie, H1
Hamdy, TA1
Shokry, YA1
El-Hennawi, DM1
Ahmed, MR2
Farid, AM1
Al Murtadah, AM1
Bakshi, SS2
Videler, WJ1
van Drunen, CM1
Reitsma, JB1
Fokkens, WJ1
Guss, J1
Abuzeid, WM1
Doghramji, L1
Edelstein, PH1
Chiu, AG1
Hekiert, AM1
Cohen, MB1
Montone, KT1
Palmer, JN1
Govindaraj, S1
Grimprel, E1
Cohen, R1
Pessey, JJ2
Fujimura, M3
Mizuguchi, M1
Nakatsumi, Y3
Mizuhashi, K1
Sasaki, S1
Yasui, M1
Iakovlev, SV1
Iakovlev, VP1
Kriukov, AI1
Sedinkin, AA1
Aleksanian, TA1
Li, XP1
Qin, ZM1
Zheng, RH1
Tan, QL1
Zhou, YY1
Zhu, L1
Yin, AF1
Henry, DC1
Kapral, D1
Busman, TA1
Paris, MM1
Anon, JB1
Gehanno, P2
Serrano, E1
Poole, M1
Anon, J1
Paglia, M1
Xiang, J1
Khashab, M1
Kahn, J1
Keating, KN1
Friedman, HS1
Perfetto, EM1
Hadley, JA1
De Benedetto, M1
Salerni, L1
De Benedetto, L1
Passali, GC1
Passali, D1
Pea, F1
Marioni, G2
Pavan, F1
Staffieri, C2
Bottin, R1
Staffieri, A2
Furlanut, M1
Rinaldi, R1
Ottaviano, G1
Marchese-Ragona, R1
Giacomelli, L1
Ferraro, SM1
Tohyama, M1
Arakaki, N1
Tamaki, K1
Shimoji, T1
Ivanov, DV1
Budanov, SV1
Marple, BF1
Roberts, CS1
de Caprariis, PJ1
Reisman, A1
Cohen, B1
Husfeldt, P1
Egede, F1
Nielsen, PB1
Gaillot, O1
Berche, P1
Ishiura, Y2
Saito, M2
Shibata, K2
Nomura, M2
Matsuda, T2
Martin, SJ1
Meyer, JM1
Chuck, SK1
Jung, R1
Messick, CR1
Pendland, SL1
Sydnor, TA1
Kopp, EJ1
Anthony, KE1
LoCoco, JM1
Kim, SS1
Fowler, CL2
Adelglass, J1
DeAbate, CA1
McElvaine, P1
LoCocco, J1
Campbell, T1
Lasko, B1
Lau, CY1
Saint-Pierre, C1
Reddington, JL1
Martel, A1
Anstey, RJ1
Ramos, P1
Hueto, J1
El'kun, GB1
Douadi, Y1
Lescure, X1
Schmit, JL1
Matsune, S1
Egawa, M1
Ohyama, M1
Kurono, Y1
Scheen, AJ1
Baba, S1

Reviews

7 reviews available for ofloxacin and Sinusitis

ArticleYear
[Update on levofloxacin in the management of acute sinusitis with risk of complications].
    Presse medicale (Paris, France : 1983), 2002, Jun-15, Volume: 31, Issue:21 Pt 2

    Topics: Abscess; Acute Disease; Anti-Infective Agents; Cellulitis; Clinical Trials as Topic; Disease Progres

2002
[Levofloxacin in the treatment of respiratory infections].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:8

    Topics: Acute Disease; Anti-Infective Agents; Bronchitis, Chronic; Clinical Trials as Topic; Drug Resistance

2002
Current management of acute bacterial rhinosinusitis and the role of moxifloxacin.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jul-15, Volume: 41 Suppl 2

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Infections; Clinical Trials as Topic; Drug Resistanc

2005
[Rhinosinusitis: etiopathogenesis and antimicrobial therapy, an update].
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2006, Volume: 26, Issue:1 Suppl 82

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Aza Compounds; Bacteria

2006
[Levofloxacin and other antibacterial drugs].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2006, Volume: 51, Issue:6

    Topics: Anti-Bacterial Agents; Bacterial Infections; Dermatitis; Dosage Forms; Humans; Levofloxacin; Ofloxac

2006
Levofloxacin and sparfloxacin: new quinolone antibiotics.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3

    Topics: Absorption; Anti-Infective Agents; Bronchitis; Drug Interactions; Drug Resistance, Microbial; Fluoro

1998
[Usefulness of levofloxacin in sinusitis].
    Enfermedades infecciosas y microbiologia clinica, 1999, Volume: 17 Suppl 1

    Topics: Anti-Infective Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Levofloxacin; O

1999

Trials

16 trials available for ofloxacin and Sinusitis

ArticleYear
Comparative study of the efficacy of topical steroid and antibiotic combination therapy versus oral antibiotic alone when treating acute rhinosinusitis.
    The Journal of laryngology and otology, 2015, Volume: 129, Issue:5

    Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Amoxicillin; Anti-Bacterial Age

2015
Nebulized bacitracin/colimycin: a treatment option in recalcitrant chronic rhinosinusitis with Staphylococcus aureus? A double-blind, randomized, placebo-controlled, cross-over pilot study.
    Rhinology, 2008, Volume: 46, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacitracin; Chron

2008
Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome.
    Respirology (Carlton, Vic.), 2002, Volume: 7, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Bronchiolitis; Bronchitis; Drug Therapy, Combina

2002
[Comparison of the effectiveness of levofloxacin and cefuroxime for the treatment of sinusitis].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2000, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Drug Administrati

2000
Cefdinir versus levofloxacin in patients with acute rhinosinusitis of presumed bacterial etiology: a multicenter, randomized, double-blind study.
    Clinical therapeutics, 2004, Volume: 26, Issue:12

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Cefdinir; Cephalosporins; Double-Blind Method; Fe

2004
[Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications].
    Medecine et maladies infectieuses, 2005, Volume: 35, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Africa, Southern; Aged; Bacterial Infections; Female; France; Haem

2005
A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 134, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Double-Blind Me

2006
Effectiveness and safety of ofloxacin in chronic otitis media and chronic sinusitis in adult outpatients.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1993, Volume: 250 Suppl 1

    Topics: Administration, Oral; Adult; Ambulatory Care; Bacterial Infections; Chronic Disease; Humans; Ofloxac

1993
Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1993, Volume: 250 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Erythromycin; Fami

1993
Additive effect of continuous low dose ofloxacin on erythromycin therapy for sinobronchial syndrome.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bronchitis; Drug Thera

1995
Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome.
    Respiratory medicine, 1995, Volume: 89, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Carbocysteine; Drug Administratio

1995
Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:4

    Topics: Acute Disease; Adult; Anti-Infective Agents; Bacterial Infections; Exudates and Transudates; Female;

1998
Comparison of the effectiveness of levofloxacin and amoxicillin-clavulanate for the treatment of acute sinusitis in adults.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1999, Volume: 120, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Am

1999
Efficacy and safety of oral levofloxacin compared with clarithromycin in the treatment of acute sinusitis in adults: a multicentre, double-blind, randomized study. The Canadian Sinusitis Study Group.
    The Journal of international medical research, 1998, Volume: 26, Issue:6

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agen

1998
[Effectiveness of maxaquin and tarivid in combined therapy of patients with chronic sinusitis].
    Vestnik otorinolaringologii, 1999, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antitubercular Agents; Chronic Disease; Drug Therapy

1999
Clinical efficacy of ofloxacin in the treatment of otorhinolaryngological infections.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Anti-Infective Agents; Bacterial Infections; Clinical Trials as Topic; Humans; Laryngitis; Ofloxacin

1986

Other Studies

18 other studies available for ofloxacin and Sinusitis

ArticleYear
Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:9

    Topics: Administration, Intranasal; Administration, Topical; Adult; Anti-Bacterial Agents; Biofilms; Case-Co

2015
Comparative study of the efficacy of topical steroid and antibiotic combination therapy versus oral antibiotic alone when treating acute rhinosinusitis.
    The Journal of laryngology and otology, 2015, Volume: 129, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Dexamethasone; Female; Glucocorticoids; Humans; Male; Ofloxacin;

2015
Comment on: Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:9

    Topics: Biofilms; Chronic Disease; Humans; Nose; Ofloxacin; Paranasal Sinuses; Rhinitis; Sinusitis

2016
Authors’ reply.
    The Journal of laryngology and otology, 2015, Volume: 129, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Dexamethasone; Female; Glucocorticoids; Humans; Male; Ofloxacin;

2015
Fluoroquinolone-resistant Pseudomonas aeruginosa in chronic rhinosinusitis.
    ORL; journal for oto-rhino-laryngology and its related specialties, 2009, Volume: 71, Issue:5

    Topics: Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Comorbidity; Drug Resistance, Bacterial; Fluo

2009
Ecthyma gangrenosum mimicking acute invasive fungal sinusitis in an immunocompromised patient.
    Ear, nose, & throat journal, 2010, Volume: 89, Issue:6

    Topics: Acetamides; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Ecthyma; Humans; Immunocompromise

2010
[Levofloxacin in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17 Suppl 4

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Child; Community-Acquired Infections; Humans; Le

2010
[Therapeutic and diagnostic policy in acute sinusitis].
    Vestnik otorinolaringologii, 2002, Issue:5

    Topics: Acute Disease; Adult; Algorithms; Anti-Bacterial Agents; Bacteria; Child; Diagnosis, Differential; H

2002
Moxifloxacin versus levofloxacin for treatment of acute rhinosinusitis: a retrospective database analysis of treatment duration, outcomes, and charges.
    Current medical research and opinion, 2006, Volume: 22, Issue:2

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Aza Compounds; Database Management Systems; Female; Flu

2006
Value of short-course antimicrobial therapy in acute bacterial rhinosinusitis.
    International journal of antimicrobial agents, 2005, Volume: 26 Suppl 3

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Azithromycin; Bacterial Infections; Dose-Response Relat

2005
Penetration of levofloxacin into paranasal sinuses mucosa of patients with chronic rhinosinusitis after a single 500 mg oral dose.
    Pharmacological research, 2007, Volume: 55, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chronic Disease; Female; H

2007
Burkholderia cepacia complex nasal isolation in immunocompetent patients with sinonasal polyposis not associated with cystic fibrosis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2007, Volume: 26, Issue:1

    Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; Burkholderi

2007
[A case of drug-induced pneumonitis due to levofloxacin and kampo medicine].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Female; Humans; Levofloxacin; Medici

2006
Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial.
    Clinical therapeutics, 2007, Volume: 29, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Dela

2007
In vitro susceptibility to ciprofloxacin of bacterial strains isolated from chronic otitis media and chronic sinusitis.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Adult; Anti-Infective Agents; Bacteria; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial;

1995
[A new antibiotic: levofloxacine].
    Presse medicale (Paris, France : 1983), 2000, Jun-17, Volume: 29, Issue:21

    Topics: Anti-Infective Agents; Bronchitis; Community-Acquired Infections; Humans; Ofloxacin; Pneumonia; Sinu

2000
Uptake of BrdU in olfactory and respiratory epithelium of rabbits with experimental sinusitis.
    Acta oto-laryngologica, 2000, Volume: 120, Issue:4

    Topics: Animals; Anti-Infective Agents; Bromodeoxyuridine; Cell Division; Immunohistochemistry; Ofloxacin; O

2000
[Pharma-clinics. The drug of the month. Levofloxacin (Tavanic)].
    Revue medicale de Liege, 2000, Volume: 55, Issue:11

    Topics: Acute Disease; Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Bronchit

2000