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ofloxacin and Sexually Transmitted Diseases

ofloxacin has been researched along with Sexually Transmitted Diseases in 16 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Sexually Transmitted Diseases: Diseases due to or propagated by sexual contact.

Research Excerpts

ExcerptRelevanceReference
"Efficacy and safety of ofloxacin (OFLX), a new quinolone antibacterial agent, were investigated in cases of sexually transmitted male urethritis and cervicitis."9.06[Efficacy of ofloxacin in sexually transmitted male urethritis and cervicitis]. ( Aso, Y; Higashihara, E; Hirose, T; Kishi, H; Kiyota, H; Kumamoto, Y; Machida, T; Okazaki, T; Sakai, S; Tsunekawa, T, 1988)
" trachomatis urethritis were treated for five days with 2 X 200 mg ofloxacin."9.06Ofloxacin: therapeutic results in Chlamydia trachomatis urethritis. ( Bischoff, W, 1986)
"Uncomplicated pelvic inflammatory disease (PID) is a common disease caused by numerous pathogens: sexually transmitted infections (such as Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium), anaerobes, and other organisms from the vaginal flora."6.74Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study. ( Judlin, P; Thiebaugeorges, O, 2009)
"Sexually transmitted diseases are an important cause of morbidity in women."6.38The clinical experience with ofloxacin in the treatment of sexually transmitted diseases. ( Corrado, ML, 1991)
"Efficacy and safety of ofloxacin (OFLX), a new quinolone antibacterial agent, were investigated in cases of sexually transmitted male urethritis and cervicitis."5.06[Efficacy of ofloxacin in sexually transmitted male urethritis and cervicitis]. ( Aso, Y; Higashihara, E; Hirose, T; Kishi, H; Kiyota, H; Kumamoto, Y; Machida, T; Okazaki, T; Sakai, S; Tsunekawa, T, 1988)
"Experience with ofloxacin in the United States in the treatment of sexually transmitted diseases is reviewed."5.06Clinical experience with ofloxacin in sexually transmitted disease. ( Beals, BS; Judson, FN; Tack, KJ, 1986)
" trachomatis urethritis were treated for five days with 2 X 200 mg ofloxacin."5.06Ofloxacin: therapeutic results in Chlamydia trachomatis urethritis. ( Bischoff, W, 1986)
"Uncomplicated pelvic inflammatory disease (PID) is a common disease caused by numerous pathogens: sexually transmitted infections (such as Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium), anaerobes, and other organisms from the vaginal flora."2.74Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study. ( Judlin, P; Thiebaugeorges, O, 2009)
"Gonorrhea, trichomoniasis, chlamydiosis and Ureaplasma infection were detected in 60, 31."2.67[Ofloxacin and ciprofloxacin in the treatment of sexually-transmitted diseases]. ( Bakalova, LA; Bednova, VN; Bugrov, AV; Kisina, VI; Navolotskaia, TI; Vakhnina, TE, 1992)
"Sexually transmitted diseases are an important cause of morbidity in women."2.38The clinical experience with ofloxacin in the treatment of sexually transmitted diseases. ( Corrado, ML, 1991)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's5 (31.25)18.2507
2000's3 (18.75)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woods, JL1
Scurlock, AM1
Hensel, DJ1
Haggerty, CL1
Ness, RB1
Judlin, P1
Thiebaugeorges, O1
Hooper, DC1
Bednova, VN1
Bakalova, LA1
Bugrov, AV1
Navolotskaia, TI1
Kisina, VI1
Vakhnina, TE1
Nakata, S1
Miki, M1
Okabe, K1
Mashimo, T1
Kobayashi, M1
Yamanaka, H1
Takahashi, O1
Onuki, T1
Corrado, ML1
Waldvogel, FA1
Neu, HC1
Kumamoto, Y1
Sakai, S1
Hirose, T1
Tsunekawa, T1
Machida, T1
Kiyota, H1
Okazaki, T1
Kishi, H1
Higashihara, E1
Aso, Y1
Hartinger, A1
Korting, HC1
Neubert, U1
Blaufuss, H1
Fransen, L1
Avonts, D1
Piot, P1
Judson, FN1
Beals, BS1
Tack, KJ1
Bischoff, W1

Reviews

3 reviews available for ofloxacin and Sexually Transmitted Diseases

ArticleYear
Diagnosis and treatment of pelvic inflammatory disease.
    Women's health (London, England), 2008, Volume: 4, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Chlamydia trachomatis; Female; Humans; Infertility, Fema

2008
New uses for new and old quinolones and the challenge of resistance.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2

    Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Humans; M

2000
The clinical experience with ofloxacin in the treatment of sexually transmitted diseases.
    American journal of obstetrics and gynecology, 1991, Volume: 164, Issue:5 Pt 2

    Topics: Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Ofloxacin; Pelvic Inflammato

1991

Trials

6 trials available for ofloxacin and Sexually Transmitted Diseases

ArticleYear
Levofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: a preliminary study.
    European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 145, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Female; Humans; Levofloxacin; Metronidazole; Ofl

2009
[Ofloxacin and ciprofloxacin in the treatment of sexually-transmitted diseases].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1992, Volume: 37, Issue:5

    Topics: Chlamydia Infections; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Female

1992
[Efficacy of ofloxacin in sexually transmitted male urethritis and cervicitis].
    The Japanese journal of antibiotics, 1988, Volume: 41, Issue:10

    Topics: Adult; Chlamydia Infections; Chlamydia trachomatis; Drug Evaluation; Female; Gonorrhea; Humans; Male

1988
Treatment of genital chlamydial infection with ofloxacin.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Doxycycline;

1986
Clinical experience with ofloxacin in sexually transmitted disease.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Clinical Trials as Topic; Double

1986
Ofloxacin: therapeutic results in Chlamydia trachomatis urethritis.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Clinical Trials as Topic;

1986

Other Studies

7 other studies available for ofloxacin and Sexually Transmitted Diseases

ArticleYear
Pelvic inflammatory disease in the adolescent: understanding diagnosis and treatment as a health care provider.
    Pediatric emergency care, 2013, Volume: 29, Issue:6

    Topics: Adolescent; Anti-Bacterial Agents; Arkansas; Ceftriaxone; Centers for Disease Control and Prevention

2013
National guideline for the management of epididymo-orchitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
    Sexually transmitted infections, 1999, Volume: 75 Suppl 1

    Topics: Anti-Bacterial Agents; Ceftriaxone; Chlamydia trachomatis; Ciprofloxacin; Doxycycline; Epididymitis;

1999
National guideline for the management of pelvic infection and perihepatitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
    Sexually transmitted infections, 1999, Volume: 75 Suppl 1

    Topics: Anti-Bacterial Agents; Cefoxitin; Ceftriaxone; Ciprofloxacin; Clindamycin; Contact Tracing; Female;

1999
[Clinical analysis of male urethritis].
    Hinyokika kiyo. Acta urologica Japonica, 1991, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Child; Gonorrhea; Humans; Japan; Lymphogranuloma Venereum; Male; Middle Aged; Min

1991
Clinical role of the quinolones today and in the future.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:12

    Topics: Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Clinical Protocols; Forecasting; Humans;

1989
Clinical use of the quinolones.
    Lancet (London, England), 1987, Dec-05, Volume: 2, Issue:8571

    Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthy

1987
[In vitro effectiveness of ofloxacin and ciprofloxacin in genital Chlamydia trachomatis isolates measured by minimal inhibitory concentration and minimal bactericidal concentration].
    Zeitschrift fur Hautkrankheiten, 1988, Jan-18, Volume: 63, Issue:1

    Topics: Chlamydia Infections; Chlamydia trachomatis; Ciprofloxacin; Dose-Response Relationship, Drug; Female

1988