ofloxacin has been researched along with Salmonella Infections, Animal in 6 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Salmonella Infections, Animal: Infections in animals with bacteria of the genus SALMONELLA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levofloxacin (L-ofloxacin) is a fluoroquinolone derivative." | 1.30 | Successful treatment of murine listeriosis and salmonellosis with levofloxacin. ( Bornitz, F; Hof, H; Kretschmar, M; Nichterlein, T, 1998) |
| " Single oral dosing of 20 mg/kg of either ofloxacin or ciprofloxacin showed that ofloxacin achieves approximately a four-fold higher peak serum or liver concentration than ciprofloxacin, which may contribute to its better efficacy in this infection model." | 1.28 | In-vivo evaluation of ofloxacin in Salmonella typhimurium infection in mice. ( Fu, KP; Hilliard, J; Isaacson, D; McGuire, JL; Rosenthale, ME; Tobia, AJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, LA | 1 |
| Luke, A | 1 |
| Sauder, K | 1 |
| Moons, DS | 1 |
| Horowitz, JC | 1 |
| Higgins, PD | 1 |
| Hung, CR | 2 |
| Wang, PS | 1 |
| Nichterlein, T | 1 |
| Bornitz, F | 1 |
| Kretschmar, M | 1 |
| Hof, H | 1 |
| Bogsch, I | 1 |
| Graf, Z | 1 |
| Seeger, K | 1 |
| Fischbach, K | 1 |
| Fu, KP | 1 |
| Hilliard, J | 1 |
| Isaacson, D | 1 |
| Tobia, AJ | 1 |
| Rosenthale, ME | 1 |
| McGuire, JL | 1 |
6 other studies available for ofloxacin and Salmonella Infections, Animal
| Article | Year |
|---|---|
Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice.
Topics: Actins; Analysis of Variance; Animals; Anti-Infective Agents; Cecum; Colitis; Colon; Cytokines; Fema | 2012 |
Gastric oxidative stress and hemorrhagic ulcer in Salmonella typhimurium-infected rats.
Topics: Allopurinol; Animals; Anti-Infective Agents; Dimethyl Sulfoxide; Free Radical Scavengers; Gastric Ju | 2004 |
Modulation of gastric hemorrhage and ulceration by oxidative stress and histamine release in Salmonella typhimurium-infected rats.
Topics: Allopurinol; Animals; Antioxidants; Dimethyl Sulfoxide; Disease Models, Animal; Gastric Juice; Gastr | 2005 |
Successful treatment of murine listeriosis and salmonellosis with levofloxacin.
Topics: Animals; Anti-Infective Agents; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, | 1998 |
[Therapy of salmonellosis in Macaca arctoides].
Topics: Administration, Oral; Animals; Chloramphenicol; Gentamicins; Macaca; Monkey Diseases; Neomycin; Oflo | 1990 |
In-vivo evaluation of ofloxacin in Salmonella typhimurium infection in mice.
Topics: Ampicillin; Animals; Chloramphenicol; Ciprofloxacin; Female; Liver; Mice; Microbial Sensitivity Test | 1990 |