Page last updated: 2024-11-01

ofloxacin and Rupture

ofloxacin has been researched along with Rupture in 19 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Rupture: Forcible or traumatic tear or break of an organ or other soft part of the body.

Research Excerpts

ExcerptRelevanceReference
"We present a rare case of spontaneous bilateral Achilles tendon rupture induced by levofloxacin, one of the fluoroquinolone antibiotics."8.82Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature. ( Amano, M; Kowatari, K; Nakashima, K; Ono, A; Toh, S; Yoshihara, M, 2004)
" We present a report of a 65-year-old woman with a bilateral Achilles tendon rupture following use of levofloxacin and corticosteroids for pneumonia."7.78[Bilateral Achilles tendon rupture following levofloxacin and glucocorticoid use]. ( Bénard, MR; Kok, LM; van Arkel, ER, 2012)
"An 80-year-old man treated by levofloxacin developed multiple tendon ruptures."7.72Rupture of multiple tendons after levofloxacin therapy. ( Bitar, S; Braun, D; Cosserat, F; Gillet, P; Loeuille, D; Petitpain, N; Trechot, P, 2004)
"We present a rare case of spontaneous bilateral Achilles tendon rupture induced by levofloxacin, one of the fluoroquinolone antibiotics."4.82Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature. ( Amano, M; Kowatari, K; Nakashima, K; Ono, A; Toh, S; Yoshihara, M, 2004)
" We present a report of a 65-year-old woman with a bilateral Achilles tendon rupture following use of levofloxacin and corticosteroids for pneumonia."3.78[Bilateral Achilles tendon rupture following levofloxacin and glucocorticoid use]. ( Bénard, MR; Kok, LM; van Arkel, ER, 2012)
"A 72-year-old female dialysis patient with insulin-dependent diabetes mellitus who was under long-term medication with oral prednisolone due to chronic obstructive pulmonary disease was given levofloxacin for one week to treat an acute bronchitis (one 500 mg dose on the first day, 125 mg/day orally from second day onwards)."3.74[Fluoroquinolone-induced Achilles tendon rupture]. ( Maurin, N, 2008)
"An 80-year-old man treated by levofloxacin developed multiple tendon ruptures."3.72Rupture of multiple tendons after levofloxacin therapy. ( Bitar, S; Braun, D; Cosserat, F; Gillet, P; Loeuille, D; Petitpain, N; Trechot, P, 2004)
"Sodium cyanide can cause severe injuries to the cornea and the anterior segment."1.38Spontaneous resolution of extensive descemet membrane detachment caused by sodium cyanide injury to the eye. ( Pan, F; Yao, YF; Zhang, B, 2012)
"We report five cases of tendinitis induced by fluoroquinolones, three caused by levofloxacin and two by ciprofloxacin."1.34[Fluoroquinolone-induced tendon diseases]. ( Bruscas Izu, C; Mauri Llerda, JA; Medrano San Ildefonso, M, 2007)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (84.21)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
London, L1
Turker, T1
Kutz, JE1
Kok, LM1
Bénard, MR1
van Arkel, ER1
Zhang, B1
Pan, F1
Yao, YF1
Greene, BL1
Pouzaud, F1
Rat, P1
Cambourieu, C1
Nourry, H1
Warnet, JM1
Tomás, ME1
Pérez Carreras, M1
Morillasa, JD1
Castellano, G1
Solís, JA1
Shah, P1
Melhus, A1
Apelqvist, J1
Larsson, J1
Eneroth, M1
Kahn, F1
Christensson, B1
Kowatari, K1
Nakashima, K1
Ono, A1
Yoshihara, M1
Amano, M1
Toh, S1
Pohjola-Sintonen, S1
Kannisto, M1
Braun, D1
Petitpain, N1
Cosserat, F1
Loeuille, D1
Bitar, S1
Gillet, P1
Trechot, P1
Lüthje, P1
Nurmi, I1
Nyyssönen, T1
Vaucher, N1
Mosquet, B1
Levast, M1
Medrano San Ildefonso, M1
Mauri Llerda, JA1
Bruscas Izu, C1
Maurin, N1
Nuño Mateo, FJ1
Noval Menéndez, J1
Suárez, M1
Guinea, O1

Reviews

1 review available for ofloxacin and Rupture

ArticleYear
Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2004, Volume: 9, Issue:2

    Topics: Achilles Tendon; Aged; Anti-Infective Agents; Appendicitis; Humans; Levofloxacin; Male; Ofloxacin; R

2004

Other Studies

18 other studies available for ofloxacin and Rupture

ArticleYear
Cough... followed by calf pain.
    Advance for nurse practitioners, 2007, Volume: 15, Issue:7

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Humans; Magnetic Resonance Imaging; Male; Ofloxacin; R

2007
Can oral levofloxacin cause of flexor digitorum profundus rupture?
    Medical hypotheses, 2011, Volume: 77, Issue:4

    Topics: Administration, Oral; Anti-Bacterial Agents; Finger Injuries; Humans; Levofloxacin; Ofloxacin; Ruptu

2011
[Bilateral Achilles tendon rupture following levofloxacin and glucocorticoid use].
    Nederlands tijdschrift voor geneeskunde, 2012, Volume: 156, Issue:13

    Topics: Achilles Tendon; Aged; Anti-Infective Agents; Casts, Surgical; Female; Glucocorticoids; Humans; Levo

2012
Spontaneous resolution of extensive descemet membrane detachment caused by sodium cyanide injury to the eye.
    Cornea, 2012, Volume: 31, Issue:11

    Topics: Burns, Chemical; Descemet Membrane; Eye Burns; Humans; Intraocular Pressure; Male; Microscopy, Acous

2012
Physical therapist management of fluoroquinolone-induced Achilles tendinopathy.
    Physical therapy, 2002, Volume: 82, Issue:12

    Topics: Achilles Tendon; Adult; Anti-Infective Agents; Humans; Levofloxacin; Male; Maxillary Sinusitis; Oflo

2002
[Tenotoxic potential of fluoroquinolones in the choice of surgical antibiotic prophylaxis in ophthalmology].
    Journal francais d'ophtalmologie, 2002, Volume: 25, Issue:9

    Topics: Achilles Tendon; Aged; Animals; Antibiotic Prophylaxis; Cells, Cultured; Ciprofloxacin; Data Interpr

2002
[Rupture of the Achilles' tendon secondary to levofloxacin].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Achilles Tendon; Adult; Ceftriaxone; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Humans

2003
Tendon abnormalities and hypersensitivity of levofloxacin.
    Prescrire international, 2003, Volume: 12, Issue:63

    Topics: Anti-Infective Agents; Humans; Hypersensitivity; Levofloxacin; Ofloxacin; Rupture; Tendons

2003
[Do tendon lesions occur during quinolone administration?].
    Deutsche medizinische Wochenschrift (1946), 2003, Oct-17, Volume: 128, Issue:42

    Topics: Achilles Tendon; Adult; Age Factors; Anti-Infective Agents; Bronchitis; Ciprofloxacin; Enzyme Inhibi

2003
Levofloxacin-associated Achilles tendon rupture and tendinopathy.
    Scandinavian journal of infectious diseases, 2003, Volume: 35, Issue:10

    Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Levofloxacin; Male;

2003
[A rapid development of Achilles tendon rupture following quinolone treatment].
    Lakartidningen, 2004, Jan-15, Volume: 101, Issue:3

    Topics: Achilles Tendon; Anti-Infective Agents, Urinary; Female; Fluoroquinolones; Humans; Middle Aged; Oflo

2004
[The rupture of both Achilles tendons as a complication from fluoroquinolone treatment].
    Duodecim; laaketieteellinen aikakauskirja, 2004, Volume: 120, Issue:8

    Topics: Achilles Tendon; Dose-Response Relationship, Drug; Drug Administration Schedule; Finland; Fluoroquin

2004
Rupture of multiple tendons after levofloxacin therapy.
    Joint bone spine, 2004, Volume: 71, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Ofloxacin; Risk Factors;

2004
Missed Achilles tendon rupture due to oral levofloxacin: surgical treatment and result.
    Archives of orthopaedic and trauma surgery, 2005, Volume: 125, Issue:2

    Topics: Achilles Tendon; Administration, Oral; Anti-Bacterial Agents; Diagnostic Errors; Humans; Levofloxaci

2005
[Achilles tendon rupture during ofloxacin treatment and a short course of prednisolone].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:9 Pt 1

    Topics: Achilles Tendon; Anti-Bacterial Agents; Glucocorticoids; Humans; Male; Middle Aged; Ofloxacin; Predn

2006
[Fluoroquinolone-induced tendon diseases].
    Anales de medicina interna (Madrid, Spain : 1984), 2007, Volume: 24, Issue:5

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary;

2007
[Fluoroquinolone-induced Achilles tendon rupture].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:6

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Bronchitis; Diabetes Mellitus, Type 1; Female; Humans;

2008
[Achilles pain and functional impotence in a patient with chronic obstructive pulmonary disease with pneumonia. Tendon rupture caused by levofloxacin].
    Revista clinica espanola, 2001, Volume: 201, Issue:9

    Topics: Achilles Tendon; Aged; Anti-Infective Agents; Humans; Levofloxacin; Male; Ofloxacin; Pain; Pneumonia

2001