Page last updated: 2024-11-01

ofloxacin and Rupture, Spontaneous

ofloxacin has been researched along with Rupture, Spontaneous in 14 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.

Research Excerpts

ExcerptRelevanceReference
" A few days before he had been treated with ciprofloxacine 500mg bid for chlamydial urethritis."3.74[Fluorquinolone associated tendon rupture]. ( Bürr, P; Haschke, M; Rätz Bravo, A; Stoll, R, 2008)
"To report a case of spontaneous bleb formation in a presumed pellucid marginal corneal degeneration with acute hydrops."1.39Spontaneous bleb formation in a presumed pellucid marginal corneal degeneration with acute hydrops. ( Higashiura, R; Inoue, T; Maeda, N; Ohashi, Y; Suzuki, T; Toriyama, K, 2013)
"We describe 7 Achilles tendinitis occurring during fluoroquinolone treatment."1.28Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy. ( Audisio, F; De Bandt, M; Hayem, G; Jorgensen, C; Kahn, MF; Meyer, O; Palazzo, E; Ribard, P, 1992)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's11 (78.57)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Toriyama, K1
Inoue, T1
Suzuki, T1
Higashiura, R1
Maeda, N1
Ohashi, Y1
Schuster, S1
Diethelm, M1
Rätz Bravo, A1
Stoll, R1
Bürr, P1
Haschke, M1
Bernácer, L1
Artigues, A1
Serrano, A1
Haddow, LJ1
Chandra Sekhar, M1
Hajela, V1
Gopal Rao, G1
Cebrian, P1
Manjon, P1
Caba, P1
de La Red, G1
Mejía, JC1
Cervera, R1
Lladó, A1
Mensa, J1
Font, J1
Lado Lado, FL1
Rodríguez Moreno, C1
Velasco González, M1
Durán Parrondo, C1
Moar Calvo, B1
Sánchez Muñoz, LA1
Sanjuán Portugal, FJ1
Naya Machado, J1
Castiella Herrero, J1
Vyas, H1
Krishnaswamy, G1
Parmar, C1
Meda, KP1
Mallari, PL1
McCarty, DJ1
Daniell, M1
Taylor, H1
Pastural, M1
Audard, V1
Bralet, MP1
Rémy, P1
Salomon, L1
Tankovic, J1
Buisson, CB1
Lang, P1
Ribard, P1
Audisio, F1
Kahn, MF1
De Bandt, M1
Jorgensen, C1
Hayem, G1
Meyer, O1
Palazzo, E1

Reviews

2 reviews available for ofloxacin and Rupture, Spontaneous

ArticleYear
Achilles tendon rupture associated with combination therapy of levofloxacin and steroid in four patients and a review of the literature.
    Foot & ankle international, 2007, Volume: 28, Issue:12

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Casts, Surgical; Female; Fol

2007
Mycoplasma hominis infection in renal transplantation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:3

    Topics: Adult; Humans; Kidney Transplantation; Male; Mycoplasma hominis; Mycoplasma Infections; Ofloxacin; R

2002

Other Studies

12 other studies available for ofloxacin and Rupture, Spontaneous

ArticleYear
Spontaneous bleb formation in a presumed pellucid marginal corneal degeneration with acute hydrops.
    Cornea, 2013, Volume: 32, Issue:6

    Topics: Acute Disease; Anti-Bacterial Agents; Aqueous Humor; Blister; Combined Modality Therapy; Corneal Dis

2013
[Achilles heel of COPD].
    Praxis, 2013, Jul-03, Volume: 102, Issue:14

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aza Compounds; Diagnosis, Di

2013
[Fluorquinolone associated tendon rupture].
    Praxis, 2008, Nov-05, Volume: 97, Issue:22

    Topics: Achilles Tendon; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Bacte

2008
[Levofloxacin and bilateral spontaneous Achilles tendon rupture].
    Medicina clinica, 2003, Jan-25, Volume: 120, Issue:2

    Topics: Achilles Tendon; Aged; Anti-Infective Agents; Confusion; Humans; Levofloxacin; Male; Ofloxacin; Rupt

2003
Spontaneous Achilles tendon rupture in patients treated with levofloxacin.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:3

    Topics: Achilles Tendon; Aged; Female; Humans; Levofloxacin; Male; Ofloxacin; Rupture, Spontaneous

2003
Ultrasonography of non-traumatic rupture of the Achilles tendon secondary to levofloxacin.
    Foot & ankle international, 2003, Volume: 24, Issue:2

    Topics: Achilles Tendon; Adult; Anti-Infective Agents; Humans; Levofloxacin; Male; Muscular Diseases; Ofloxa

2003
Bilateral Achilles tendinitis with spontaneous rupture induced by levofloxacin in a patient with systemic sclerosis.
    Clinical rheumatology, 2003, Volume: 22, Issue:4-5

    Topics: Achilles Tendon; Cyclophosphamide; Drug Therapy, Combination; Follow-Up Studies; Humans; Levofloxaci

2003
[Partial bilateral rupture of the Achilles tendon associated to levofloxacin].
    Anales de medicina interna (Madrid, Spain : 1984), 2005, Volume: 22, Issue:1

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Ofloxacin; Rupture, Sponta

2005
[Levofloxacin-induced tendon rupture with fatal outcome].
    Anales de medicina interna (Madrid, Spain : 1984), 2006, Volume: 23, Issue:2

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Comorbidity; Fatal Outcome; Humans; Levofloxacin; Male

2006
Images in clinical medicine. Quinolone-associated rupture of the Achilles' tendon.
    The New England journal of medicine, 2007, Nov-15, Volume: 357, Issue:20

    Topics: Achilles Tendon; Aged, 80 and over; Anti-Bacterial Agents; Bronchitis; Female; Humans; Magnetic Reso

2007
Increased incidence of corneal perforation after topical fluoroquinolone treatment for microbial keratitis.
    American journal of ophthalmology, 2001, Volume: 131, Issue:1

    Topics: Anti-Infective Agents; Bacteria; Cornea; Corneal Diseases; Corneal Ulcer; Eye Infections, Bacterial;

2001
Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy.
    The Journal of rheumatology, 1992, Volume: 19, Issue:9

    Topics: Achilles Tendon; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cystitis; Female; Human

1992