ofloxacin has been researched along with Rhabdomyolysis in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of ofloxacin/levofloxacin-induced rhabdomyolysis and to compare other reported cases from the literature." | 8.82 | Acute rhabdomyolysis associated with ofloxacin/levofloxacin therapy. ( Chang, CM; Hsiao, SH; Hsu, MY; Lee, YY; Tsao, CJ; Wu, TJ, 2005) |
| "Rhabdomyolysis is a well-known complication of various drug therapies." | 5.38 | Levofloxacin-induced rhabdomyolysis in a hemodialysis patient. ( Bell, R; Gupta, A; Guron, N; Harris, M, 2012) |
| "Levofloxacin is a recent fluoroquinolone and its muscular toxicity is not well documented." | 5.32 | A case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin. ( Debien, B; Nadaud, J; Olive, F; Pats, B; Perez, JP; Petitjeans, F; Villevieille, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, A | 1 |
| Guron, N | 1 |
| Harris, M | 1 |
| Bell, R | 1 |
| Petitjeans, F | 1 |
| Nadaud, J | 1 |
| Perez, JP | 1 |
| Debien, B | 1 |
| Olive, F | 1 |
| Villevieille, T | 1 |
| Pats, B | 1 |
| Hsiao, SH | 1 |
| Chang, CM | 1 |
| Tsao, CJ | 1 |
| Lee, YY | 1 |
| Hsu, MY | 1 |
| Wu, TJ | 1 |
| Korzets, A | 1 |
| Gafter, U | 1 |
| Dicker, D | 1 |
| Herman, M | 1 |
| Ori, Y | 1 |
| Baril, L | 1 |
| Maisonobe, T | 1 |
| Jasson-Molinier, M | 1 |
| Haroche, J | 1 |
| Bricaire, F | 1 |
| Caumes, E | 1 |
1 review available for ofloxacin and Rhabdomyolysis
| Article | Year |
|---|---|
Acute rhabdomyolysis associated with ofloxacin/levofloxacin therapy.
Topics: Adult; Anti-Bacterial Agents; Creatine Kinase; Humans; Levofloxacin; Male; Ofloxacin; Rhabdomyolysis | 2005 |
4 other studies available for ofloxacin and Rhabdomyolysis
| Article | Year |
|---|---|
Levofloxacin-induced rhabdomyolysis in a hemodialysis patient.
Topics: Aged; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Ofloxacin; Renal Dialysis; Rhabdomyolysis | 2012 |
A case of rhabdomyolysis with fatal outcome after a treatment with levofloxacin.
Topics: Aged; Anti-Infective Agents; Fatal Outcome; Female; Humans; Levofloxacin; Ofloxacin; Rhabdomyolysis | 2003 |
Levofloxacin and rhabdomyolysis in a renal transplant patient.
Topics: Aged; Anti-Bacterial Agents; Humans; Kidney Transplantation; Levofloxacin; Male; Ofloxacin; Rhabdomy | 2006 |
Acute rhabdomyolysis during treatment with ofloxacin-a case report.
Topics: Acute Disease; Anti-Infective Agents; Escherichia coli Infections; Female; Humans; Middle Aged; Oflo | 1999 |