ofloxacin has been researched along with Retinal Diseases in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Retinal Diseases: Diseases involving the RETINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ocular bioavailability of ofloxacin in aqueous humor after oral and topical administration is similar when the drug is applied as described." | 1.30 | Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration. ( Basci, NE; Batman, C; Bozkurt, A; Cekic, O; Kayaalp, SO; Yasar, U, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butler, NJ | 1 |
| Suhler, EB | 1 |
| Lai, WW | 1 |
| Chu, KO | 1 |
| Chan, KP | 1 |
| Choy, KW | 1 |
| Wang, CC | 1 |
| Tsang, CW | 1 |
| Pang, CP | 1 |
| Cekic, O | 1 |
| Batman, C | 1 |
| Yasar, U | 1 |
| Basci, NE | 1 |
| Bozkurt, A | 1 |
| Kayaalp, SO | 1 |
1 trial available for ofloxacin and Retinal Diseases
| Article | Year |
|---|---|
Differential aqueous and vitreous concentrations of moxifloxacin and ofloxacin after topical administration one hour before vitrectomy.
Topics: Adult; Aged; Anti-Infective Agents; Aqueous Humor; Aza Compounds; Biological Availability; Chromatog | 2007 |
2 other studies available for ofloxacin and Retinal Diseases
| Article | Year |
|---|---|
Levofloxacin-associated panuveitis with chorioretinal lesions.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Bites and Stings; Female; | 2012 |
Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration.
Topics: Administration, Oral; Administration, Topical; Anti-Infective Agents; Aqueous Humor; Chromatography, | 1998 |