ofloxacin has been researched along with Retinal Detachment in 1 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Retinal Detachment: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ocular bioavailability of ofloxacin in SRF after oral and combined administration is equivalent." | 2.69 | Penetration of topical, oral, and combined administered ofloxacin into the subretinal fluid. ( Basci, NE; Batman, C; Bozkurt, A; Cekiç, O; Kayaalp, SO; Totan, Y; Yasar, U; Zilelioglu, O, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cekiç, O | 1 |
| Batman, C | 1 |
| Yasar, U | 1 |
| Totan, Y | 1 |
| Basci, NE | 1 |
| Bozkurt, A | 1 |
| Zilelioglu, O | 1 |
| Kayaalp, SO | 1 |
1 trial available for ofloxacin and Retinal Detachment
| Article | Year |
|---|---|
Penetration of topical, oral, and combined administered ofloxacin into the subretinal fluid.
Topics: Administration, Oral; Administration, Topical; Adult; Anti-Infective Agents; Antibiotic Prophylaxis; | 1999 |