Page last updated: 2024-11-01

ofloxacin and Pulmonary Fibrosis

ofloxacin has been researched along with Pulmonary Fibrosis in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
"We reported a case of fibrosing alveolitis following Legionella pneumonia."1.31[Fibrosing alveolitis following Legionella pneumonia]. ( Hatakeyama, S; Oka, T; Suzuki, K; Tachibana, A; Tateda, K; Yamaguchi, K, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suzuki, K1
Tachibana, A1
Hatakeyama, S1
Oka, T1
Yamaguchi, K1
Tateda, K1
Raffi, F1

Other Studies

2 other studies available for ofloxacin and Pulmonary Fibrosis

ArticleYear
[Fibrosing alveolitis following Legionella pneumonia].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2000, Volume: 38, Issue:4

    Topics: Anti-Inflammatory Agents; Clarithromycin; Drug Therapy, Combination; Humans; Legionnaires' Disease;

2000
Q-fever endocarditis.
    Lancet (London, England), 1989, Dec-02, Volume: 2, Issue:8675

    Topics: Endocarditis, Bacterial; Female; Humans; Middle Aged; Ofloxacin; Pulmonary Fibrosis; Q Fever

1989