Page last updated: 2024-11-01

ofloxacin and Prostatitis

ofloxacin has been researched along with Prostatitis in 62 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Prostatitis: Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment.

Research Excerpts

ExcerptRelevanceReference
"Levofloxacin is a synthetic fluoroquinolone that is usually used to treat chronic bacterial prostatitis."9.16Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients. ( Guo, YL; Jin, FS; Liu, DM; Shen, ZJ; Sun, YH; Zhang, ZC, 2012)
"To compare the safety and efficacy of levofloxacin 750 mg QD for 2 weeks or levofloxacin 750 mg QD for 3 weeks to levofloxacin 500 mg QD for 4 weeks in treating chronic bacterial prostatitis (CBP)."9.14Safety and efficacy of levofloxacin 750 mg for 2 weeks or 3 weeks compared with levofloxacin 500 mg for 4 weeks in treating chronic bacterial prostatitis. ( Fisher, AC; Kahn, JB; Nicholson, SC; Paglia, M; Peterson, J; Qin, Z, 2010)
"The aim of this study was to confirm further the efficacy and safety of levofloxacin in patients with chronic bacterial prostatitis (CBP) in Europe."9.13Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis. ( Botto, H; Naber, KG; Roscher, K; Schaefer, V, 2008)
"For a 6-week short-term treatment levofloxacin is more effective than doxazosin for chronic prostatitis/chronic pelvic pain syndrome."9.13Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination. ( Jeong, CW; Jeong, H; Lee, SE; Lim, DJ; Son, H, 2008)
"To evaluate the clinical efficacy of the Chinese medicine Yiqigushen Capsule combined with levofloxacin on type III A prostatitis."9.13[Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis]. ( Guo, DF; Wang, HP; Zhang, HZ, 2008)
"Ninety-six patients with chronic bacterial prostatitis (CBP) and evidence of infection were randomized to receive a 4-week oral course of either prulifloxacin (a new fluoroquinolone) 600 mg or levofloxacin 500 mg once daily."9.12Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial. ( Barbone, F; De Maria, M; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2007)
"Longqingpian combined with Levofloxacin is highly effective for Type IIIA prostatitis, by relieving pain and voiding symptoms, decreasing the leukocyte count in EPS and improving the life quality of the patients."9.12[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis]. ( Cai, X; Huang, YF; Shang, XJ; Teng, WH; Xu, H, 2007)
"Subset analysis was done using a randomized, multicenter, double-blind, active control trial of 500 mg levofloxacin daily for 28 days vs 500 mg ciprofloxacin twice daily in 28 days in men with chronic bacterial prostatitis."9.11Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen. ( Kahn, JB; Schaeffer, AJ; Tennenberg, AM; Wu, SC, 2005)
"To compare the safety and efficacy of levofloxacin with that of ciprofloxacin for the treatment of chronic bacterial prostatitis."9.10Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study. ( Bundrick, W; Heron, SP; Kahn, JB; Ray, P; Schiff, WM; Tennenberg, AM; Wiesinger, BA; Wright, PA; Wu, SC; Zadeikis, N, 2003)
"To perform a Canadian multicenter randomized placebo-controlled trial to evaluate the safety and efficacy of 6 weeks of levofloxacin therapy compared with placebo in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)."9.10Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial. ( Barkin, J; Brock, G; Casey, RW; Clark, J; Downey, J; Flax, S; Goldfarb, B; Nickel, JC; Palmer, BW; Patrick, AB; Pommerville, PJ; Steinhoff, G; Zadra, J, 2003)
"Studies of ofloxacin pharmacokinetics and pathogen susceptibilities suggested that this new fluoroquinolone might be particularly well suited to the treatment of urinary tract infections and prostatitis."9.06Ofloxacin in the management of complicated urinary tract infections, including prostatitis. ( Cox, CE, 1989)
"The combination of levofloxacin and α1 adrenergic antagonist treatment is the current preferred choice for both bacterial and non-bacterial prostatitis."7.79Tamsulosin alters levofloxacin pharmacokinetics in prostates derived from rats with acute bacterial prostatitis. ( He, HX; He, Y; Qin, GD; Xiao, MZ; Yang, J; Zeng, Y; Zhou, YD, 2013)
"The aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (NIH-II) in the daily clinical routine of urologists in their practices."7.77[Practice management of chronic bacterial prostatitis with levofloxacin]. ( Naber, KG; Roscher, K; Wagenlehner, F, 2011)
"To evaluate the effect of levofloxacin (LVX) oral therapy on total serum prostate specific antigen (PSA) values in patients with histological prostatitis."7.72PSA decrease after levofloxacin therapy in patients with histological prostatitis. ( Bollito, E; Cracco, C; Guercio, S; Poggio, M; Scarpa, RM; Tarabuzzi, R; Terrone, C, 2004)
"Ofloxacin (OFLX), a new pyridonecarboxylic acid derivative for oral use, was administered in the treatment of 22 cases of bacterial prostatitis (acute 4, chronic 18)."7.67[Laboratory and clinical study of ofloxacin in the treatment of bacterial prostatitis]. ( Ando, K; Moriguchi, R; Naide, Y; Suzuki, K; Tamai, H, 1984)
"Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12."5.28[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992)
"Levofloxacin is a synthetic fluoroquinolone that is usually used to treat chronic bacterial prostatitis."5.16Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients. ( Guo, YL; Jin, FS; Liu, DM; Shen, ZJ; Sun, YH; Zhang, ZC, 2012)
"We obtained NIH-CPSI and IIEF-5 scores from 132 chronic prostatitis patients with ED and divided the patients into a control (n = 70) and a treatment group (n = 62), the former treated with oral levofloxacin 0."5.16[Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction]. ( Chao, WF; Huang, XK; Liang, P; Liu, JW; Wang, L; Wang, QT; Yang, H; Yang, W; Zhou, P, 2012)
"To compare the safety and efficacy of levofloxacin 750 mg QD for 2 weeks or levofloxacin 750 mg QD for 3 weeks to levofloxacin 500 mg QD for 4 weeks in treating chronic bacterial prostatitis (CBP)."5.14Safety and efficacy of levofloxacin 750 mg for 2 weeks or 3 weeks compared with levofloxacin 500 mg for 4 weeks in treating chronic bacterial prostatitis. ( Fisher, AC; Kahn, JB; Nicholson, SC; Paglia, M; Peterson, J; Qin, Z, 2010)
"For a 6-week short-term treatment levofloxacin is more effective than doxazosin for chronic prostatitis/chronic pelvic pain syndrome."5.13Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination. ( Jeong, CW; Jeong, H; Lee, SE; Lim, DJ; Son, H, 2008)
"The aim of this study was to confirm further the efficacy and safety of levofloxacin in patients with chronic bacterial prostatitis (CBP) in Europe."5.13Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis. ( Botto, H; Naber, KG; Roscher, K; Schaefer, V, 2008)
"To evaluate the clinical efficacy of the Chinese medicine Yiqigushen Capsule combined with levofloxacin on type III A prostatitis."5.13[Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis]. ( Guo, DF; Wang, HP; Zhang, HZ, 2008)
"Ninety-six patients with chronic bacterial prostatitis (CBP) and evidence of infection were randomized to receive a 4-week oral course of either prulifloxacin (a new fluoroquinolone) 600 mg or levofloxacin 500 mg once daily."5.12Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial. ( Barbone, F; De Maria, M; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2007)
"Longqingpian combined with Levofloxacin is highly effective for Type IIIA prostatitis, by relieving pain and voiding symptoms, decreasing the leukocyte count in EPS and improving the life quality of the patients."5.12[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis]. ( Cai, X; Huang, YF; Shang, XJ; Teng, WH; Xu, H, 2007)
"Subset analysis was done using a randomized, multicenter, double-blind, active control trial of 500 mg levofloxacin daily for 28 days vs 500 mg ciprofloxacin twice daily in 28 days in men with chronic bacterial prostatitis."5.11Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen. ( Kahn, JB; Schaeffer, AJ; Tennenberg, AM; Wu, SC, 2005)
"To perform a Canadian multicenter randomized placebo-controlled trial to evaluate the safety and efficacy of 6 weeks of levofloxacin therapy compared with placebo in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)."5.10Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial. ( Barkin, J; Brock, G; Casey, RW; Clark, J; Downey, J; Flax, S; Goldfarb, B; Nickel, JC; Palmer, BW; Patrick, AB; Pommerville, PJ; Steinhoff, G; Zadra, J, 2003)
"To compare the safety and efficacy of levofloxacin with that of ciprofloxacin for the treatment of chronic bacterial prostatitis."5.10Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study. ( Bundrick, W; Heron, SP; Kahn, JB; Ray, P; Schiff, WM; Tennenberg, AM; Wiesinger, BA; Wright, PA; Wu, SC; Zadeikis, N, 2003)
"Studies of ofloxacin pharmacokinetics and pathogen susceptibilities suggested that this new fluoroquinolone might be particularly well suited to the treatment of urinary tract infections and prostatitis."5.06Ofloxacin in the management of complicated urinary tract infections, including prostatitis. ( Cox, CE, 1989)
"The combination of levofloxacin and α1 adrenergic antagonist treatment is the current preferred choice for both bacterial and non-bacterial prostatitis."3.79Tamsulosin alters levofloxacin pharmacokinetics in prostates derived from rats with acute bacterial prostatitis. ( He, HX; He, Y; Qin, GD; Xiao, MZ; Yang, J; Zeng, Y; Zhou, YD, 2013)
"The aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (NIH-II) in the daily clinical routine of urologists in their practices."3.77[Practice management of chronic bacterial prostatitis with levofloxacin]. ( Naber, KG; Roscher, K; Wagenlehner, F, 2011)
"Men with prostatitis-like symptoms and any bacteria localized to prostate specific specimens were treated with levofloxacin or ciprofloxacin for 4 weeks with 6 months of followup."3.74Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis. ( Nickel, JC; Xiang, J, 2008)
"To evaluate the effect of levofloxacin (LVX) oral therapy on total serum prostate specific antigen (PSA) values in patients with histological prostatitis."3.72PSA decrease after levofloxacin therapy in patients with histological prostatitis. ( Bollito, E; Cracco, C; Guercio, S; Poggio, M; Scarpa, RM; Tarabuzzi, R; Terrone, C, 2004)
"Ofloxacin (OFLX), a new pyridonecarboxylic acid derivative for oral use, was administered in the treatment of 22 cases of bacterial prostatitis (acute 4, chronic 18)."3.67[Laboratory and clinical study of ofloxacin in the treatment of bacterial prostatitis]. ( Ando, K; Moriguchi, R; Naide, Y; Suzuki, K; Tamai, H, 1984)
"Ofloxacin, a new fluoroquinolone, was given to fifty patients (29 females and 21 males) aged 25 to 86 years with urinary tract infection or prostatitis."3.67[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections]. ( Acar, JF; Guibert, J, 1986)
"In this study, 20 men suffering from acute nongonococcal epididymitis were treated with ofloxacin 200mg bid given orally for 2 weeks."3.67Acute nongonococcal epididymitis. Aetiological and therapeutic aspects. ( Garbe, C; Schiefer, HG; Weidner, W, 1987)
"Prednisone in combination with an antibiotic can effectively relieve pain and voiding symptoms, improve QOL and reduce WBC in the EPS of CNP patients, and therefore well deserves to be recommended in clinical application."2.74[Corticoid combined with an antibiotic for chronic nonbacterial prostatitis]. ( Hou, Y; Lü, C; Wu, ZP; Xiao, N; Yang, MG; Zhao, XK, 2009)
"Tosufloxacin was as effective as levofloxacin when administered twice daily for 2 days as prophylaxis for TBP, which suggests that this regimen is useful for reducing the clinical and febrile infection rate following TBP."2.73Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin. ( Ishitoya, S; Kamoto, T; Ogawa, O; Okumura, K; Segawa, T; Yamamoto, S, 2008)
"Levofloxacin has such an activity profile."2.69A population pharmacokinetic analysis of the penetration of the prostate by levofloxacin. ( Boccumini, L; Corrado, M; Drusano, GL; Gombert, M; Kahn, J; North, D; Oefelein, M; Preston, SL; Van Guilder, M; Weisinger, B, 2000)
" In practice, adverse events (AEs) of BCG therapy could restrict its prescription by urologists."2.48[Diagnosis and management of adverse events occuring during BCG therapy for non-muscle invasive bladder cancer (NMIBC): review of the Cancer Committee of the French Association of Urology]. ( Davin, JL; Irani, J; Larré, S; Moreau, JL; Neuzillet, Y; Pfister, C; Pignot, G; Rouprêt, M; Soulié, M; Wallerand, H, 2012)
"Prostate cancer was detected in 20% of patients with a clinically relevant PSA decline."1.37Antimicrobial therapy for asymptomatic patients with elevated prostate-specific antigen: can the change in prostate-specific antigen reliably guide prostate biopsy decisions? ( Abdelhamid, M; Emran, A; Kamal, A; Mosharafa, A; Torky, M, 2011)
"coli."1.37Prevalence of fluoroquinolone-resistant Escherichia coli before and incidence of acute bacterial prostatitis after prostate biopsy. ( Baba, S; Fujita, T; Iwamura, M; Kimura, M; Kurosaka, S; Matsumoto, K; Minamida, S; Satoh, T; Tabata, K; Tsumura, H, 2011)
"Bacterial prostatitis is documented at a very low prevalence (7-13% of prostatitis overall considered) due to either reduced utilization of viral and bacteriological tests (Meares test, urethral swab, bacterial and viral PCR) or to the possibility that individual patients show a scarce expression of bacterial disease in biological fluids, because of intraglandular biofilm presence, with subsequent spreading of the sole plankton microrganisms."1.35[Chronic prostatitis and biofilm]. ( Bartoletti, R; Cai, T, 2009)
"Prostate cancer was found in 10."1.33Effects of antibacterial therapy on PSA change in the presence and absence of prostatic inflammation in patients with PSA levels between 4 and 10 ng/ml. ( Cetinkaya, M; Inal, G; Kaygisiz, O; Koşan, M; Oztürk, B; Uğurlu, O, 2006)
"Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12."1.28[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19907 (11.29)18.7374
1990's8 (12.90)18.2507
2000's32 (51.61)29.6817
2010's15 (24.19)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naber, KG3
Roscher, K2
Botto, H1
Schaefer, V1
Yang, MG1
Zhao, XK1
Wu, ZP1
Xiao, N1
Lü, C1
Hou, Y1
Shigemura, K1
Yasufuku, T1
Yamashita, M1
Arakawa, S1
Fujisawa, M1
Bartoletti, R2
Cai, T2
Paglia, M1
Peterson, J1
Fisher, AC1
Qin, Z1
Nicholson, SC1
Kahn, JB3
Mirone, V1
Magri, V1
Marras, E1
Skerk, V1
Markotić, A1
Restelli, A1
Garlaschi, MC1
Perletti, G1
Wagenlehner, F1
Mazzoli, S1
Meacci, F1
Boddi, V1
Mondaini, N1
Malossini, G1
Panas, M1
Karadima, G1
Kalfakis, N1
Vassilopoulos, D1
Minamida, S1
Satoh, T1
Tabata, K1
Kimura, M1
Tsumura, H1
Kurosaka, S1
Matsumoto, K1
Fujita, T1
Iwamura, M1
Baba, S1
Torky, M1
Mosharafa, A1
Emran, A1
Kamal, A1
Abdelhamid, M1
Faydaci, G1
Eryildirim, B1
Tarhan, F1
Goktas, C1
Tosun, C1
Kuyumcuoglu, U1
Oliveira-Reis, L1
Zhang, ZC1
Jin, FS1
Liu, DM1
Shen, ZJ1
Sun, YH1
Guo, YL1
La Vignera, S1
Condorelli, RA1
Calogero, AE1
Bellanca, S1
Salmeri, M1
Vicari, E2
Neuzillet, Y1
Rouprêt, M1
Wallerand, H1
Pignot, G1
Larré, S1
Irani, J1
Davin, JL1
Moreau, JL1
Soulié, M1
Pfister, C1
Kuz'menko, VV1
Kuz'menko, AV1
Kurnosova, NV1
Wang, L1
Liang, P1
Yang, W1
Zhou, P1
Huang, XK1
Liu, JW1
Chao, WF1
Yang, H1
Wang, QT1
Qin, GD1
Xiao, MZ1
Zhou, YD1
Yang, J1
He, HX1
He, Y1
Zeng, Y1
Sachs, HP1
Zhou, LQ1
Shen, M1
Zhao, Y1
Seo, SI1
Lee, SJ1
Kim, JC1
Choi, YJ1
SW, SW1
Hwang, TK1
Cho, YH1
Jeon, SS1
Woo, SH1
Hyun, JH1
Choi, HY1
Chai, SE1
Bundrick, W1
Heron, SP1
Ray, P1
Schiff, WM1
Tennenberg, AM2
Wiesinger, BA1
Wright, PA1
Wu, SC2
Zadeikis, N1
Nickel, JC3
Downey, J2
Clark, J2
Casey, RW1
Pommerville, PJ1
Barkin, J1
Steinhoff, G1
Brock, G1
Patrick, AB1
Flax, S1
Goldfarb, B1
Palmer, BW1
Zadra, J1
Ginsburg, AS1
Woolwine, SC1
Hooper, N1
Benjamin, WH1
Bishai, WR1
Dorman, SE1
Sterling, TR1
Guercio, S1
Terrone, C1
Tarabuzzi, R1
Poggio, M1
Cracco, C1
Bollito, E1
Scarpa, RM1
Schaeffer, AJ1
Smelov, V1
Perekalina, T1
Artemenko, N1
Smelova, N1
Ukleeva, G1
Gorelov, A1
Pust, RA1
Ackenheil-Koppe, HR1
Gilbert, P1
Weidner, W2
Makaryus, AN1
Byrns, K1
Makaryus, MN1
Natarajan, U1
Singer, C1
Goldner, B1
Olapade-Olaopa, EO1
Adebayo, SA1
Kaygisiz, O1
Uğurlu, O1
Koşan, M1
Inal, G1
Oztürk, B1
Cetinkaya, M1
Xu, H1
Shang, XJ1
Cai, X1
Teng, WH1
Huang, YF1
Giannarini, G1
Mogorovich, A1
Valent, F1
Morelli, G1
De Maria, M1
Manassero, F1
Barbone, F1
Selli, C1
Xiang, J1
Shigehara, K1
Miyagi, T1
Nakashima, T2
Shimamura, M1
Guo, DF1
Zhang, HZ1
Wang, HP1
Jeong, CW1
Lim, DJ1
Son, H1
Lee, SE1
Jeong, H1
Kobayashi, M1
Nukui, A1
Morita, T1
Yamamoto, S1
Ishitoya, S1
Segawa, T1
Kamoto, T1
Okumura, K1
Ogawa, O1
Hara, S1
Nakasu, H1
Suzuki, K2
Tamai, H1
Naide, Y1
Ando, K1
Moriguchi, R1
Espiritu, J1
Walton, T1
Ohkawa, M1
Yamaguchi, K1
Tokunaga, S1
Shoda, R1
Pfau, A1
Hennenfent, BR1
Feliciano, AE1
Nishimura, T1
Abe, H1
Ito, H1
Ikeda, K1
Oka, F1
Yamamoto, M1
Drusano, GL1
Preston, SL1
Van Guilder, M1
North, D1
Gombert, M1
Oefelein, M1
Boccumini, L1
Weisinger, B1
Corrado, M1
Kahn, J1
Johnston, B1
Karazanashvili, G1
Managadze, L1
Trinchiere, A1
Bravo, JL1
Horiba, M1
Asakawa, M1
Yasumoto, R1
Cox, CE1
Schiefer, HG1
Garbe, C1
Guibert, J1
Acar, JF1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-Blind, Phase 3B Study to Compare the Safety and Clinical Efficacy of Levofloxacin in 750mg for 2 Weeks and Levofloxacin 750mg for 3 Weeks to That of Levofloxacin 500mg for 4 Weeks in the Treatment of Chronic Prostatitis[NCT00402688]Phase 3242 participants (Actual)Interventional2006-11-30Completed
A Randomized Controlled Trial to Investigate the Infectious Outcomes of Intrarectal Povidone-iodine Cleansing Plus Formalin Disinfection of Needle Tip During Transrectal Ultrasound Guided Prostate Biopsy[NCT03879486]1,257 participants (Actual)Interventional2017-05-31Completed
A Multicenter, Double-Blind Study to Compare the Safety and Efficacy of Levofloxacin to That of Ciprofloxacin in the Treatment of Chronic Prostatitis[NCT00236808]Phase 3383 participants (Actual)Interventional2000-05-31Completed
A Study to Understand the Treatment Patterns in Patients With Chronic Bacterial Prostatitis (Category II), Chronic Pelvic Pain (Category IIIA, IIIB)Treataprost Added to Standard Antibiotic Treatment in Real-life Clinical Practice[NCT05306314]140 participants (Anticipated)Observational2022-04-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Clinical Success

Defined as cured or improved. Response is based on the resolution of signs and symptoms at post-therapy. (NCT00402688)
Timeframe: Posttherapy Visit (Study Day 33-36)

InterventionParticipants (Number)
Levofloxacin 750mg for 2 Weeks46
Levofloxacin 750mg for 3 Weeks48
Levofloxacin 500mg for 4 Weeks52

Clinical Success (Non-Relapse) or Failure (Relapse)

Number of Clinical Successes or Failures at 3 Month Poststudy Telephone Contact for Participants Cured/Improved at the Posttherapy Visit (NCT00402688)
Timeframe: Poststudy Telephone contact at 3 Months

,,
InterventionParticipants (Number)
Clinical SuccessFailureUnable to EvaluateMissing
Levofloxacin 500mg for 4 Weeks38419
Levofloxacin 750mg for 2 Weeks30808
Levofloxacin 750mg for 3 Weeks246117

Clinical Success (Non-Relapse) or Failure (Relapse)

Number of Clinical Successes or Failures at the 6-month Poststudy Telephone Contact For Participants Cured/Improved at the Posttherapy Visit (NCT00402688)
Timeframe: Poststudy Telephone Contact at 6 Months

,,
InterventionParticipants (Number)
Clinical SuccessFailureUnable to EvaluateMissing
Levofloxacin 500mg for 4 Weeks316114
Levofloxacin 750mg for 2 Weeks1910116
Levofloxacin 750mg for 3 Weeks194124

Clinical Success (Non-Relapse) or Failure (Relapse)

Number of Clinical Successes or Failures at the 6-Week Poststudy Telephone Contact for Participants Cured/Improved at the Posttherapy Visit (NCT00402688)
Timeframe: Poststudy Telephone contact at 6 weeks

,,
Interventionparticipants (Number)
Clinical SuccessFailureUnable to EvaluateMissing
Levofloxacin 500mg for 4 Weeks44512
Levofloxacin 750mg for 2 Weeks38305
Levofloxacin 750mg for 3 Weeks321213

Symptom Relief (Resolved)

Participants With Resolution of Prostatitis Signs and Symptoms; Resolution is defined as symptoms present (mild, moderate or severe) at Screening/Admission and absent (none) at the Posttherapy evaluation. (NCT00402688)
Timeframe: Posttherapy Visit (Study Day 33-36)

,,
InterventionParticipants (Number)
Dysuria (n=35, 43, 42)Suprapubic discomfort (n=41, 36, 45)Painful ejaculation (n=32, 39, 34)Low back pain (n=43, 44, 44)Perineal discomfort (n=40, 42, 50)Frequency (n=58, 63, 62)Urgency (n=48, 52, 58)Hesitancy (n=37, 39, 54)Decreased urinary stream (n=50, 47, 52)Urinary retention (n=24, 26, 27)Pain on digital rectal examination (n=60, 59, 61)Perineal tenderness or pain (n=44, 38, 43)Chills (n=4, 5, 7)Other (n=5, 8, 8)Fever (n=3, 2, 1)
Levofloxacin 500mg for 4 Weeks273020262930353830174228751
Levofloxacin 750mg for 2 Weeks232417202029201924133028312
Levofloxacin 750mg for 3 Weeks291923221924281621133024352

Total NIH-CPSI Score

National Institute of Health-Chronic Prostatitis Symptom Index numerically rates a total score (0-43) where 0 indicates no symptoms across any of the domains (pain or discomfort, urination, quality of life). (NCT00402688)
Timeframe: Screening/Admission, On-Therapy, Week 3, Week 4, Posttherapy (Study Day 33-36)

,,
InterventionScore on a scale (Mean)
Screening/Admission (n=73, 74, 75)On-Therapy (n=70, 70, 73)Week 3 (Visit 2) (n=62, 65, 68)Week 4 (Visit 3) (n=53, 57, 61)Posttherapy (Visit 4) (n=70, 71, 71)
Levofloxacin 500mg for 4 Weeks12.96.95.64.54.6
Levofloxacin 750mg for 2 Weeks11.87.26.55.15.4
Levofloxacin 750mg for 3 Weeks12.06.66.54.95.0

Reviews

4 reviews available for ofloxacin and Prostatitis

ArticleYear
[From cystitis to bacterial prostatitis: experience with levofloxacin].
    Le infezioni in medicina, 2009, Volume: 17 Suppl 5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cystitis; Double-Blind Method; Drug Therapy, Combinatio

2009
[Diagnosis and management of adverse events occuring during BCG therapy for non-muscle invasive bladder cancer (NMIBC): review of the Cancer Committee of the French Association of Urology].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2012, Volume: 22, Issue:16

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Anti-Infective Agents, Urinary; Arthralgia; BC

2012
Levofloxacin in the treatment of urinary tract infections and prostatitis.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 2

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug

2004
[Role of levofloxacin in the treatment of urinary tract infections].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2001, Volume: 73, Issue:2

    Topics: Anti-Infective Agents, Urinary; Female; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Urinary

2001

Trials

19 trials available for ofloxacin and Prostatitis

ArticleYear
Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis.
    International journal of antimicrobial agents, 2008, Volume: 32, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Chronic Disease; Gram-Negative Bacteria; Gram-Po

2008
[Corticoid combined with an antibiotic for chronic nonbacterial prostatitis].
    Zhonghua nan ke xue = National journal of andrology, 2009, Volume: 15, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Double-Blind Method; Drug Therapy

2009
Safety and efficacy of levofloxacin 750 mg for 2 weeks or 3 weeks compared with levofloxacin 500 mg for 4 weeks in treating chronic bacterial prostatitis.
    Current medical research and opinion, 2010, Volume: 26, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Double-Blind Method; Humans; L

2010
[Does antibiotherapy prevent unnecessary prostate biopsies in patients with high PSA values?].
    Actas urologicas espanolas, 2012, Volume: 36, Issue:4

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroi

2012
Safety and efficacy of levofloxacin versus ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients.
    Asian journal of andrology, 2012, Volume: 14, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Asian People; Ciprofloxacin; Escherichia coli Infections; Humans; Levo

2012
[Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction].
    Zhonghua nan ke xue = National journal of andrology, 2012, Volume: 18, Issue:10

    Topics: Adult; Capsules; Chronic Disease; Drugs, Chinese Herbal; Erectile Dysfunction; Humans; Levofloxacin;

2012
Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study.
    Urology, 2003, Volume: 62, Issue:3

    Topics: Adult; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; Double-Blind Met

2003
Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial.
    Urology, 2003, Volume: 62, Issue:4

    Topics: Adult; Aged; Anti-Infective Agents; Chronic Disease; Double-Blind Method; Humans; Levofloxacin; Male

2003
Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen.
    The Journal of urology, 2005, Volume: 174, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections;

2005
[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis].
    Zhonghua nan ke xue = National journal of andrology, 2007, Volume: 13, Issue:4

    Topics: Adult; Chronic Disease; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Phytotherapy; Prostatiti

2007
Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial.
    Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Chronic Disease; Dioxolanes; Double-Blind Method; Fluoroquinolones; Hu

2007
[Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis].
    Zhonghua nan ke xue = National journal of andrology, 2008, Volume: 14, Issue:1

    Topics: Adult; Anti-Infective Agents, Urinary; Capsules; Chronic Disease; Drug Therapy, Combination; Drugs,

2008
Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination.
    Urologia internationalis, 2008, Volume: 80, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Anti-Bacterial Agents; Doxazosin; Drug Therapy, Combination; Hu

2008
Antibiotic prophylaxis for transrectal prostate biopsy: a prospective randomized study of tosufloxacin versus levofloxacin.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Cystitis; Fluoroq

2008
Antimicrobial treatment for chronic prostatitis as a means of defining the role of Ureaplasma urealyticum.
    Urologia internationalis, 1993, Volume: 51, Issue:3

    Topics: Adult; Aged; Chronic Disease; Humans; Leukocyte Count; Male; Middle Aged; Minocycline; Ofloxacin; Pr

1993
A population pharmacokinetic analysis of the penetration of the prostate by levofloxacin.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Demography; Humans; Levofloxacin; Male; Middle Aged;

2000
Effectiveness and limits of antimicrobial treatment on seminal leukocyte concentration and related reactive oxygen species production in patients with male accessory gland infection.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Doxycycline; Epididymitis; Femal

2000
Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial.
    The Journal of urology, 2001, Volume: 165, Issue:5

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibodies, Bacterial; Bacteria; Bacterial In

2001
Ofloxacin in the management of complicated urinary tract infections, including prostatitis.
    The American journal of medicine, 1989, Dec-29, Volume: 87, Issue:6C

    Topics: Administration, Oral; Adult; Aged; Bacterial Infections; Carbenicillin; Drug Resistance, Microbial;

1989

Other Studies

39 other studies available for ofloxacin and Prostatitis

ArticleYear
Prophylactic use of isepamicin and levofloxacin for transrectal prostate biopsy: a retrospective single center study.
    International journal of urology : official journal of the Japanese Urological Association, 2009, Volume: 16, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy

2009
[Chronic prostatitis and biofilm].
    Le infezioni in medicina, 2009, Volume: 17 Suppl 1

    Topics: Adult; Biofilms; Chronic Disease; Ciprofloxacin; Contraception Behavior; Diet; Disease Susceptibilit

2009
Eradication of Chlamydia trachomatis parallels symptom regression in chronic bacterial prostatitis patients treated with a fluoroquinolone-macrolide combination.
    Andrologia, 2010, Volume: 42, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Drug Therap

2010
[Practice management of chronic bacterial prostatitis with levofloxacin].
    Aktuelle Urologie, 2011, Volume: 42, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Chronic Disease; Escherichia coli

2011
Epidemiological features and resistance pattern in uropathogens isolated from chronic bacterial prostatitis.
    Journal of microbiology (Seoul, Korea), 2011, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Enterococcus fa

2011
Hereditary neuropathy unmasked by levofloxacin.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:10

    Topics: Anti-Bacterial Agents; Charcot-Marie-Tooth Disease; Diagnosis, Differential; Family Health; Humans;

2011
Prevalence of fluoroquinolone-resistant Escherichia coli before and incidence of acute bacterial prostatitis after prostate biopsy.
    Urology, 2011, Volume: 78, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy, Needle; Carba

2011
Antimicrobial therapy for asymptomatic patients with elevated prostate-specific antigen: can the change in prostate-specific antigen reliably guide prostate biopsy decisions?
    Urologia internationalis, 2011, Volume: 87, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Asymptomatic Diseases; Biopsy; Diagnostic Errors; Drug Administration S

2011
[Prostate specific antigen decrease and prostate cancer diagnosis: recognizing the fundamental previous progresses and moving forward].
    Actas urologicas espanolas, 2012, Volume: 36, Issue:8

    Topics: Anti-Bacterial Agents; Biopsy, Needle; Humans; Male; Ofloxacin; Prostate; Prostate-Specific Antigen;

2012
Persistence of ultrasound alterations after antibiotic treatment with levofloxacin in patients with male accessory gland infection.
    Asian journal of andrology, 2012, Volume: 14, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Epididymis; Epididymitis; Genital Diseases, Male; Humans; Levofloxacin

2012
[Correction of psychoemotional status in patients with chronic bacterial prostatitis].
    Terapevticheskii arkhiv, 2012, Volume: 84, Issue:10

    Topics: Adult; Anti-Anxiety Agents; Anti-Infective Agents, Urinary; Biureas; Drug Therapy, Combination; Huma

2012
Tamsulosin alters levofloxacin pharmacokinetics in prostates derived from rats with acute bacterial prostatitis.
    Asian journal of andrology, 2013, Volume: 15, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Anti-Bacterial Agents; Drug Interactions; Escheric

2013
Consider the cost when prescribing antibiotics.
    American family physician, 2002, Sep-01, Volume: 66, Issue:5

    Topics: Anti-Infective Agents, Urinary; Cost-Benefit Analysis; Doxycycline; Humans; Male; Ofloxacin; Prostat

2002
[Detection of bacterial 16S rRAN gene in EPS of men with chronic pelvic pain syndrome and its clinical significance].
    Zhonghua nan ke xue = National journal of andrology, 2003, Volume: 9, Issue:4

    Topics: Anti-Bacterial Agents; Azithromycin; Chronic Disease; Humans; Levofloxacin; Male; Ofloxacin; Pelvic

2003
Effects of androgen deprivation on chronic bacterial prostatitis in a rat model.
    International journal of urology : official journal of the Japanese Urological Association, 2003, Volume: 10, Issue:9

    Topics: Androgen Antagonists; Animals; Anti-Infective Agents, Urinary; Castration; Chronic Disease; Enzyme I

2003
Bisacodyl rectal preparation can decrease infectious complications of transrectal ultrasound-guided prostate biopsy.
    Urology, 2003, Volume: 62, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Administration, Rectal; Adult; Aged; Aged, 80 and over; Antibi

2003
The rapid development of fluoroquinolone resistance in M. tuberculosis.
    The New England journal of medicine, 2003, Nov-13, Volume: 349, Issue:20

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Ciprofloxacin; Drug Resistance,

2003
PSA decrease after levofloxacin therapy in patients with histological prostatitis.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2004, Volume: 76, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Prostate-Specific A

2004
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
    Andrologia, 2005, Volume: 37, Issue:2-3

    Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxaci

2005
Clinical efficacy of ofloxacin (tarivid) in patients with chronic bacterial prostatitis: preliminary results.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adult; Anti-Infective Agents; Bacterial Infections; Clinical Trials as Topic; Escherichia coli Infec

1989
Effect of ciprofloxacin and levofloxacin on the QT interval: is this a significant "clinical" event?
    Southern medical journal, 2006, Volume: 99, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Electrocardiography; F

2006
Re: treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen.
    The Journal of urology, 2006, Volume: 175, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin;

2006
Effects of antibacterial therapy on PSA change in the presence and absence of prostatic inflammation in patients with PSA levels between 4 and 10 ng/ml.
    Prostate cancer and prostatic diseases, 2006, Volume: 9, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Biopsy; Carcinoma; Diagnosis, Differential; Humans; Male; Middle Aged;

2006
Clinical significance of nontraditional bacterial uropathogens in the management of chronic prostatitis.
    The Journal of urology, 2008, Volume: 179, Issue:4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Escherichia coli; Gram-Positive Bacteria; Humans; Levofloxacin

2008
Acute bacterial prostatitis after transrectal prostate needle biopsy: clinical analysis.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2008, Volume: 14, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Biopsy, Needle; Blood; Carbapenems; Cephalosporins; Drug Resistance, Ba

2008
Serum PSA and percent free PSA value changes after antibiotic treatment. A diagnostic method in prostate cancer suspects with asymptomatic prostatitis.
    Urologia internationalis, 2008, Volume: 80, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Humans; Male; Ofloxacin; Prostate-Specific Antigen; Prostatic Neoplasms

2008
[The investigation of prostatic fluid and tissue levels of DL-8280 and clinical study of DL-8280 in acute prostatitis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1984, Volume: 58, Issue:9

    Topics: Acute Disease; Adult; Anti-Infective Agents; Humans; Male; Middle Aged; Ofloxacin; Oxazines; Prostat

1984
[Laboratory and clinical study of ofloxacin in the treatment of bacterial prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1984, Volume: 30, Issue:10

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Evalu

1984
Acute renal failure due to ofloxacin.
    The West Virginia medical journal, 1995, Volume: 91, Issue:1

    Topics: Acute Kidney Injury; Aged; Fatal Outcome; Humans; Male; Ofloxacin; Prostatitis

1995
Oral ofloxacin: a critical review of the new drug application.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:2

    Topics: Administration, Oral; Escherichia coli Infections; Humans; Investigational New Drug Application; Mal

1993
Changes in white blood cell counts in men undergoing thrice-weekly prostatic massage, microbial diagnosis and antimicrobial therapy for genitourinary complaints.
    British journal of urology, 1998, Volume: 81, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Bacterial Infections; Drug

1998
IL-1ra versus IL-1 levels in prostatic fluid from prostatitis patients.
    Urologia internationalis, 1998, Volume: 60, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacterial Infections; Body Fluids; C

1998
National guideline for the management of prostatitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
    Sexually transmitted infections, 1999, Volume: 75 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, U

1999
Prostate-specific antigen (PSA) value change after antibacterial therapy of prostate inflammation, as a diagnostic method for prostate cancer screening in cases of PSA value within 4-10 ng/ml and nonsuspicious results of digital rectal examination.
    European urology, 2001, Volume: 39, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Humans; Male; Mass Screening; Middle Aged; Ofloxacin

2001
[Ofloxacin: a new ally in the treatment of urinary infections and bacterial prostatitis].
    Archivos espanoles de urologia, 1992, Volume: 45, Issue:2

    Topics: Bacterial Infections; Humans; Male; Ofloxacin; Prostatitis; Urinary Tract Infections

1992
[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis].
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:6

    Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Epididymitis; Escherichia coli; Humans;

1992
Ofloxacin concentration in human benign prostatic tissue after oral administration.
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:6

    Topics: Administration, Oral; Aged; Aged, 80 and over; Humans; Male; Ofloxacin; Prostate; Prostatic Hyperpla

1988
Acute nongonococcal epididymitis. Aetiological and therapeutic aspects.
    Drugs, 1987, Volume: 34 Suppl 1

    Topics: Acute Disease; Adolescent; Adult; Aging; Anti-Infective Agents; Epididymitis; Humans; Male; Middle A

1987
[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections].
    Pathologie-biologie, 1986, Volume: 34, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cystitis; Female; Humans; Male; Middle Age

1986