ofloxacin has been researched along with Postoperative Complications in 72 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized, open, prospective study including 45 patients with either soft tissue infections (29 cases) or pneumonia (15 cases) after surgical intervention and one case having both indications was carried out with ofloxacin." | 9.06 | Treatment of surgical infections with a modern quinolone: therapy of soft tissue infections and pneumonia with ofloxacin. ( Fritzen, T; Marx, E; Uy, J, 1986) |
| " Hypoglycemia because of use of levofloxacin is a rarely reported complication." | 7.74 | Fatal hypoglycemia with levofloxacin use in an elderly patient in the post-operative period. ( Abraham, J; Jacob, JJ; Kapoor, R; Singh, M, 2008) |
| " We compared the efficacy of oral levofloxacin (LVFX) and intravenous cephazolin (CEZ) in patients receiving TACE/TAI for hepatocellular carcinoma (HCC) using a prospective design." | 5.14 | Antibiotic prophylaxis in transcatheter treatment of hepatocellular carcinoma: an open randomized prospective study of oral versus intravenous administration. ( Ebisutani, C; Inoue, H; Kinoshita, Y; Nishi, K; Sato, S; Yoshie, T, 2010) |
| "This partially masked randomized placebo-controlled multinational clinical study was designed to evaluate prospectively the prophylactic effect of intracameral cefuroxime and/or perioperative topical levofloxacin on postoperative endophthalmitis after cataract surgery." | 5.12 | ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study. ( Barry, P; Gettinby, G; Lees, F; Peterson, M; Revie, CW; Seal, DV; Wilhelmus, KR, 2006) |
| "This partially masked randomized placebo-controlled multinational clinical study to evaluate prospectively the prophylactic effect of intracameral cefuroxime injection and/or perioperative levofloxacin eyedrops on the incidence of endophthalmitis after phacoemulsification cataract surgery began in September 2003 and was terminated early in January 2006." | 5.12 | ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study. ( Barry, P; Gettinby, G; Lees, F; Peterson, M; Revie, CW; Seal, DV, 2006) |
| "Use of intracameral cefuroxime at the end of surgery reduced the occurrence of postoperative endophthalmitis." | 5.12 | Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors. ( , 2007) |
| "The purpose of this prospective, randomized study was to evaluate the effect of oral ofloxacin prophylaxis on endotoxin/cytokine release in aortic aneurysm repair, in 25 patients with infrarenal aortic aneurysm at a University hospital." | 5.10 | Oral antibiotic prophylaxis can influence the inflammatory response in aortic aneurysm repair: results of a randomized clinical study. ( Holzheimer, RG, 2003) |
| "Perioperative use of ofloxacin for prophylaxis was investigated in 20 patients with focal hepatic formations (hemangioma, adenocarcinoma, echinococcosis)." | 5.10 | [Perioperative management of focal liver diseases by ofloxacin]. ( Elagina, LV; Ikramov, RZ; Izotova, GN; Khlebnikov, EP; Kybyshkin, VA; Pavlova, MV; Vishnevskiĭ, VA, 2002) |
| "A randomized, open, prospective study including 45 patients with either soft tissue infections (29 cases) or pneumonia (15 cases) after surgical intervention and one case having both indications was carried out with ofloxacin." | 5.06 | Treatment of surgical infections with a modern quinolone: therapy of soft tissue infections and pneumonia with ofloxacin. ( Fritzen, T; Marx, E; Uy, J, 1986) |
| "Our protocol to achieve high aqueous humor concentrations of levofloxacin may be favorable in preventing endophthalmitis after eye surgery." | 3.77 | Efficient penetration into aqueous humor by administration of oral and topical levofloxacin. ( Ishida, M; Iwaki, M; Kataoka, T; Niwa, K; Zako, M, 2011) |
| "To present a case of advancing keratoconus treated with corneal collagen cross-linking (CXL) with ultraviolet A (UVA) light and riboflavin complicated with sterile infiltrates." | 3.76 | Corneal infiltrates after corneal collagen cross-linking. ( Balidis, MO; Mangioris, GF; Papadopoulos, NT; Papadopoulou, DN; Poulas, JL; Seiler, T, 2010) |
| " Renal-dose levofloxacin was utilized as part of an antimicrobial regimen to treat post-operative peritonitis." | 3.74 | Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia. ( Gregory, J; Huesmann, G; Jakoby, MG; Vallurupalli, S, 2008) |
| " Hypoglycemia because of use of levofloxacin is a rarely reported complication." | 3.74 | Fatal hypoglycemia with levofloxacin use in an elderly patient in the post-operative period. ( Abraham, J; Jacob, JJ; Kapoor, R; Singh, M, 2008) |
| "Prostate cancer was detected in 34." | 2.73 | Time of administration of a single dose of oral levofloxacin and its effect in infectious complications from transrectal prostate biopsy. ( Argyropoulos, AN; Doumas, K; Farmakis, A; Gkialas, I; Liakatas, I; Lykourinas, M, 2007) |
| "He suddenly fell into septic shock about 12 hours after the biopsy." | 1.36 | [Septic shock due to fluoroquinolone-resistant Escherichia coli after trans-rectal prostate needle biopsy]. ( Fujishima, Y; Kato, R; Matsuura, T; Obara, W; Sato, K; Shimaya, R; Suzuki, Y; Tokiwa, S, 2010) |
| "Clarithromycin (CAM) was started for M." | 1.33 | [A case of Mycobacterium fortuitum meningitis following surgery for meningioma]. ( Eguchi, K; Fujikawa, K; Fukuda, T; Motomura, M; Ooe, N; Suenaga, A, 2006) |
| "levofloxacin has proven to be successful reducing the recurrence rate." | 1.32 | [Mitigated erysipelas after implantation of foreign material]. ( Sauer, J; Seifert, A; Weyer, T, 2004) |
| "Because increased hepatotoxicity was observed with first line antituberculous agents using four drug standard induction therapy in orthotopic liver transplant patients, we evaluated the efficacy and adverse effects of a novel continuation regimen for the treatment of tuberculosis in orthotopic liver transplant patients at a University Hospital in New York City." | 1.31 | Tuberculosis in orthotopic liver transplant patients: increased toxicity of recommended agents; cure of disseminated infection with nonconventional regimens. ( Emre, S; Meyers, BR; Miller, C; Papanicolaou, GA; Sheiner, P, 2000) |
| "Ten patients with clinical symptoms of benign prostatic hyperplasia undergoing TUR-P received 200 mg of both drugs per os simultaneously 2 hours before surgery." | 1.31 | Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate. ( Chen, J; Chen, RR; Huang, HS, 2001) |
| "Ciprofloxacin was the quinolone of choice in 24/32 (75%) of assessable cases." | 1.29 | An audit of ciprofloxacin use in a district general hospital. ( Fenelon, LE; MacGowan, AP; Reeves, DS; Smyth, EG; Speirs, GE; Speller, DC; Wilcox, MH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (9.72) | 18.7374 |
| 1990's | 8 (11.11) | 18.2507 |
| 2000's | 46 (63.89) | 29.6817 |
| 2010's | 10 (13.89) | 24.3611 |
| 2020's | 1 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Wang, Y | 2 |
| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, J | 7 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
| Bi, Z | 1 |
| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
| Richter, C | 1 |
| Edelhäuser, BAH | 1 |
| Engelmann, D | 1 |
| Brenmoehl, J | 1 |
| Söhnchen, C | 1 |
| Murr, N | 1 |
| Alpers, M | 1 |
| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
| Liao, Y | 1 |
| Cheng, J | 1 |
| Kong, X | 1 |
| Li, S | 1 |
| Zhang, M | 4 |
| Zhang, H | 1 |
| Yang, T | 2 |
| Dong, Y | 1 |
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| Hu, J | 2 |
| Wang, H | 2 |
| Liu, Y | 4 |
| Mi, Y | 1 |
| Kong, H | 1 |
| Xi, D | 1 |
| Yan, W | 1 |
| Luo, X | 1 |
| Ning, Q | 1 |
| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
| Reddy, K | 1 |
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| Ma, WY | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
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| Gao, F | 1 |
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| Cai, X | 1 |
| Ji, RY | 1 |
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| Zhu, ZQ | 1 |
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| Shi, ZE | 1 |
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| Chen, S | 2 |
| Fu, D | 1 |
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| Celestrin, CP | 1 |
| Rocha, GZ | 1 |
| Stein, AM | 1 |
| Guadagnini, D | 1 |
| Tadelle, RM | 1 |
| Saad, MJA | 1 |
| Oliveira, AG | 1 |
| Bianconi, V | 1 |
| Bronzo, P | 1 |
| Banach, M | 1 |
| Sahebkar, A | 1 |
| Mannarino, MR | 1 |
| Pirro, M | 1 |
| Patsourakos, NG | 1 |
| Kouvari, M | 1 |
| Kotidis, A | 1 |
| Kalantzi, KI | 1 |
| Tsoumani, ME | 1 |
| Anastasiadis, F | 1 |
| Andronikos, P | 1 |
| Aslanidou, T | 1 |
| Efraimidis, P | 1 |
| Georgiopoulos, A | 1 |
| Gerakiou, K | 1 |
| Grigoriadou-Skouta, E | 1 |
| Grigoropoulos, P | 1 |
| Hatzopoulos, D | 1 |
| Kartalis, A | 1 |
| Lyras, A | 1 |
| Markatos, G | 1 |
| Mikrogeorgiou, A | 1 |
| Myroforou, I | 1 |
| Orkopoulos, A | 1 |
| Pavlidis, P | 1 |
| Petras, C | 1 |
| Riga, M | 1 |
| Skouloudi, M | 1 |
| Smyrnioudis, N | 1 |
| Thomaidis, K | 1 |
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| Tsikouris, EI | 1 |
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| Vavoulis, P | 1 |
| Vitali, MG | 1 |
| Vitsas, G | 1 |
| Vogiatzidis, C | 1 |
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| Solis Condor, R | 1 |
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| Sebayang, SK | 1 |
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| Kuswanto, H | 1 |
| Foroutan, T | 1 |
| Ahmadi, F | 1 |
| Moayer, F | 1 |
| Khalvati, S | 1 |
| Zhang, Q | 2 |
| Lyu, Y | 1 |
| Huang, J | 1 |
| Yu, N | 1 |
| Wen, Z | 1 |
| Hou, H | 1 |
| Zhao, T | 1 |
| Gupta, A | 1 |
| Khosla, N | 1 |
| Govindasamy, V | 1 |
| Saini, A | 1 |
| Annapurna, K | 1 |
| Dhakate, SR | 1 |
| Akkaya, Ö | 1 |
| Chandgude, AL | 1 |
| Dömling, A | 1 |
| Harnett, J | 1 |
| Oakes, K | 1 |
| Carè, J | 1 |
| Leach, M | 1 |
| Brown, D | 1 |
| Cramer, H | 1 |
| Pinder, TA | 1 |
| Steel, A | 1 |
| Anheyer, D | 1 |
| Cantu, J | 1 |
| Valle, J | 1 |
| Flores, K | 1 |
| Gonzalez, D | 1 |
| Valdes, C | 1 |
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| Padilla, V | 1 |
| Alcoutlabi, M | 1 |
| Parsons, J | 1 |
| Núñez, K | 1 |
| Hamed, M | 1 |
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| Bruce, D | 1 |
| Thevenot, P | 1 |
| Cohen, A | 1 |
| Weber, P | 1 |
| Menezes, AMB | 1 |
| Gonçalves, H | 1 |
| Perez-Padilla, R | 1 |
| Jarvis, D | 1 |
| de Oliveira, PD | 1 |
| Wehrmeister, FC | 1 |
| Mir, S | 1 |
| Wong, J | 1 |
| Ryan, CM | 1 |
| Bellingham, G | 1 |
| Singh, M | 3 |
| Waseem, R | 1 |
| Eckert, DJ | 1 |
| Chung, F | 1 |
| Hegde, H | 1 |
| Shimpi, N | 1 |
| Panny, A | 1 |
| Glurich, I | 1 |
| Christie, P | 1 |
| Acharya, A | 1 |
| English, KL | 1 |
| Downs, M | 1 |
| Goetchius, E | 1 |
| Buxton, R | 1 |
| Ryder, JW | 1 |
| Ploutz-Snyder, R | 1 |
| Guilliams, M | 1 |
| Scott, JM | 1 |
| Ploutz-Snyder, LL | 1 |
| Martens, C | 1 |
| Goplen, FK | 1 |
| Aasen, T | 1 |
| Gjestad, R | 1 |
| Nordfalk, KF | 1 |
| Nordahl, SHG | 1 |
| Inoue, T | 1 |
| Soshi, S | 1 |
| Kubota, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intracameral Levofloxacin (0.5%) Versus Intracameral Cefuroxime (1mg/0.1ml) Effect on Corneal Endothelial Cell Count and Morphology in Uneventful Phacoemulsification[NCT04212078] | Phase 1/Phase 2 | 138 participants (Anticipated) | Interventional | 2019-07-29 | Recruiting | ||
| Neutrophil and Lymphocyte Counts and the Neutrophil-to-lymphocyte Ratio as a Predictor of Fever Following Percutaneous Nephrolithotomy in Patients Without Risk Factors[NCT03774940] | 519 participants (Actual) | Interventional | 2005-01-01 | Completed | |||
| The Effects on Betadine 5% Penetration When Using Lidocaine 2% Jelly Versus Topical Tetracaine 0.5% for Topical Phacoemulsification Cataract Surgery.[NCT00827073] | 40 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| Antibiotic Prophylaxis for Cataract Surgery Version 7e January 22 2003[NCT00136344] | 35,000 participants | Interventional | 2003-09-30 | Completed | |||
| Contribution of Fast Molecular Bacterial Identification by Real-time PCR in Managing of Postoperative Acute Endophthalmitis[NCT02850653] | 150 participants (Anticipated) | Interventional | 2007-11-30 | Recruiting | |||
| Use of Intracameral Moxifloxacin for the Prevention of Acute Endophthalmitis Following Cataract Surgery: a Controlled and Randomized Clinical Trial[NCT02770729] | Phase 3 | 3,640 participants (Actual) | Interventional | 2017-01-31 | Terminated | ||
| Phase 4 Study on Effectiveness of Topical 0.5% Levofloxacin on Reduction of Preoperative Conjunctival Flora in Patients Scheduled for Intraocular Surgery[NCT00491049] | Phase 4 | 140 participants (Actual) | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Within 3 hours from time of culture acquisition, the samples will be vortexed for 30 seconds and 100µl aliquots will be plated onto 5% sheep blood and chocolate agar plates. These plates will be incubated with 5% carbon dioxide at 35˚ C for 72 hours. After 72 hours all plates will be read for colony count and identification of all isolates will be performed using routine microbiological methods. The natural log of bacterial bacterial colony count will be used for the outcome measure. (NCT00827073)
Timeframe: (1) Pre-antibiotics swab, and (2) Post-study medication (pre surgery)
| Intervention | Ln(bacterial colony count) (Mean) |
|---|---|
| Tetracaine 0.5% Drop | -0.14 |
| Lidocaine 2% Jelly | -0.52 |
(NCT00827073)
Timeframe: (1) Pre-antibiotics swab and (2) Post-study medication (pre surgery)
| Intervention | bacterial spceies (Mean) | |
|---|---|---|
| pre number of bacterial spices | post surgery number of bacterial speices | |
| Lidocaine 2% Jelly | 1 | 1 |
| Tetracaine 0.5% Drop | 1 | 1 |
3 reviews available for ofloxacin and Postoperative Complications
16 trials available for ofloxacin and Postoperative Complications
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Antibiotic prophylaxis in transcatheter treatment of hepatocellular carcinoma: an open randomized prospective study of oral versus intravenous administration.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Carcinoma, Hepatocellular; Ce | 2010 |
A prospective randomized study of thin versus regular-sized guide wire in wire-guided cannulation.
Topics: Adult; Aged; Aged, 80 and over; Alloys; Antibiotic Prophylaxis; Catheterization; Cholangiopancreatog | 2013 |
Antibiotic prophylaxis in percutaneous nephrolithotomy: prospective study in 81 patients.
Topics: Adult; Antibiotic Prophylaxis; Bacteriuria; Dose-Response Relationship, Drug; Drug Administration Sc | 2002 |
Oral antibiotic prophylaxis can influence the inflammatory response in aortic aneurysm repair: results of a randomized clinical study.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Aortic Aneurysm; Calcito | 2003 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime | 2006 |
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime | 2006 |
Ofloxacin otic drops vs neomycin-polymyxin B otic drops as prophylaxis against early postoperative tympanostomy tube otorrhea.
Topics: Administration, Topical; Anti-Bacterial Agents; Cerebrospinal Fluid Otorrhea; Child, Preschool; Fema | 2006 |
Time of administration of a single dose of oral levofloxacin and its effect in infectious complications from transrectal prostate biopsy.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biopsy, Needle; Humans; Levofl | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors.
Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Endophthalmitis; | 2007 |
A prospective randomized study to determine the efficacy of preoperative topical levofloxacin in reducing conjunctival bacterial flora.
Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Bacteriologi | 2008 |
[Efficacy of lomefloxacin in treatment of nonspecific inflammatory diseases and in prophylaxis of postoperative complications in urology].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Female; F | 1998 |
Complicating risk factors for pyelonephritis after extracorporeal shock wave lithotripsy.
Topics: Adolescent; Adult; Age Distribution; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Humans; Kidn | 2000 |
Ofloxacin and ursodeoxycholic acid versus ursodeoxycholic acid alone to prevent occlusion of biliary stents: a prospective, randomized trial.
Topics: Aged; Anti-Infective Agents; Bile Duct Neoplasms; Cholagogues and Choleretics; Cholestasis, Extrahep | 2001 |
[Perioperative management of focal liver diseases by ofloxacin].
Topics: Adenocarcinoma; Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Antibody Formation; Echi | 2002 |
Treatment of surgical infections with a modern quinolone: therapy of soft tissue infections and pneumonia with ofloxacin.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topi | 1986 |
54 other studies available for ofloxacin and Postoperative Complications
| Article | Year |
|---|---|
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia.
Topics: Anti-Bacterial Agents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Hypoglycemia; Kidne | 2008 |
Third- and fourth-generation fluoroquinolones: retrospective comparison of endophthalmitis after cataract surgery performed over 10 years.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprof | 2008 |
Preventive effect against post-cataract endophthalmitis: drug delivery intraocular lens versus intracameral antibiotics.
Topics: Animals; Anterior Chamber; Anti-Bacterial Agents; Aqueous Humor; Biological Availability; Cataract E | 2008 |
Fluoroquinolones and postoperative endophthalmitis.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Endophthalmitis; Eye In | 2009 |
Fluoroquinolones and postoperative endophthalmitis.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Ciprofloxacin; Endophthalmitis; Eye In | 2009 |
Gelatin sponge insertion into tympanostomy tubes: an in-vitro study to evaluate postoperative obstruction.
Topics: Analysis of Variance; Anti-Bacterial Agents; Blood; Gelatin Sponge, Absorbable; Humans; In Vitro Tec | 2009 |
A case of late-onset diffuse lamellar keratitis 12 years after laser in situ keratomileusis.
Topics: Betamethasone; Cornea; Drug Therapy, Combination; Humans; Keratitis; Keratomileusis, Laser In Situ; | 2010 |
Corneal infiltrates after corneal collagen cross-linking.
Topics: Adult; Collagen; Corneal Diseases; Corneal Stroma; Cross-Linking Reagents; Drug Therapy, Combination | 2010 |
[Septic shock due to fluoroquinolone-resistant Escherichia coli after trans-rectal prostate needle biopsy].
Topics: Biopsy, Needle; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; L | 2010 |
Efficient penetration into aqueous humor by administration of oral and topical levofloxacin.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cataract Extraction; Chromatog | 2011 |
Concurrent postpartum uterine and abdominal wall dehiscence and Streptococcus anginosus infection.
Topics: Abdominal Wall; Acute Disease; Adolescent; Anti-Bacterial Agents; Ascitic Fluid; Cefazolin; Cesarean | 2011 |
Long-term outcome and prognostic factor analysis for keratolimbal allografts.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Corneal Diseases; Cyclosporine; Epithelium, Corne | 2011 |
[Antibioprophylaxis in ocular surgery. Recommendations].
Topics: Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Cefuroxime | 2011 |
Significant visual increase following infectious keratitis after collagen cross-linking.
Topics: Anti-Bacterial Agents; Collagen; Corneal Stroma; Corneal Topography; Corneal Ulcer; Cross-Linking Re | 2012 |
Corneal flap complications in refractive surgery: Part 2: postoperative treatments of diffuse lamellar keratitis in an experimental animal model.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Corneal Stroma; Disease Mod | 2003 |
Effect of flap hinge placement on post-laser in situ keratomileusis wound healing in the presence of superior corneal vascularization.
Topics: Adult; Anti-Infective Agents; Corneal Edema; Corneal Neovascularization; Corneal Stroma; Corneal Top | 2003 |
[Mitigated erysipelas after implantation of foreign material].
Topics: Aged; Anti-Infective Agents; Arthroplasty, Replacement; Arthroplasty, Replacement, Hip; Disease Prog | 2004 |
Candida parapsilosis keratitis following treatment of epithelial ingrowth after laser in situ keratomileusis.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Debridement; Drug Therapy, Combination; Epithelium, | 2004 |
Severe corneal edema after temporomandibular joint reconstruction: report of a case.
Topics: Adolescent; Ankylosis; Anti-Infective Agents; Corneal Edema; Female; Humans; Ofloxacin; Postoperativ | 2004 |
Postoperative Corynebacterium macginleyi endophthalmitis.
Topics: Aged; Aqueous Humor; Bacterial Typing Techniques; Cataract Extraction; Chronic Disease; Corynebacter | 2004 |
A retrospective study of endophtalmitis rates comparing quinolone antibiotics.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Cross | 2005 |
A retrospective study of endophthalmitis rates comparing quinolone antibiotics.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization Review; Endophthalmitis; Eye Infections, Bact | 2005 |
A retrospective study of endophthalmitis rates comparing quinolone antibiotics.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization Review; Endophthalmitis; Eye Infections, Bact | 2005 |
A retrospective study of endophthalmitis rates comparing quinolone antibiotics.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Utilization Review; Endophthalmitis; Eye Infections, Bact | 2005 |
Antibiotic susceptibility of slime-producing isolates from orthopedic patients.
Topics: Anti-Bacterial Agents; Cefotaxime; Clindamycin; Colony-Forming Units Assay; Humans; Imipenem; Microb | 1989 |
The activity of ofloxacin compared to spiramycin in oral surgery.
Topics: Bacterial Infections; Clinical Trials as Topic; Humans; Ofloxacin; Oral Surgical Procedures; Postope | 1989 |
Experience with ofloxacin for short and long-term treatment of urinary tract infections in renal transplant recipients.
Topics: Follow-Up Studies; Humans; Kidney Transplantation; Ofloxacin; Postoperative Complications; Recurrenc | 1989 |
[Clinical efficacy and cost benefit of oral antimicrobial prophylaxis with levofloxacin on neurological surgery].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; | 2006 |
ESCRS study of endophthalmitis prophylaxis.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime | 2006 |
[A case of Mycobacterium fortuitum meningitis following surgery for meningioma].
Topics: Clarithromycin; Female; Humans; Levofloxacin; Meningeal Neoplasms; Meningioma; Meningitis, Bacterial | 2006 |
[Musculoskeletal adverse effects of levofloxacin].
Topics: Anti-Bacterial Agents; Arthralgia; Arthritis; Arthritis, Infectious; Arthroplasty, Replacement, Knee | 2006 |
Diaphragm paralysis in children after cardiac surgery.
Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Cefazolin; Diaphragm; Female; Heart Defects, Con | 2007 |
Methicillin-resistant Staphylococcus aureus infectious keratitis following refractive surgery.
Topics: Adult; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bacterial; Female; Health Personnel | 2007 |
Delayed intraocular foreign body removal without endophthalmitis during Operations Iraqi Freedom and Enduring Freedom.
Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Combined Modality Therapy; Endophthalmitis; Eye Enuclea | 2007 |
[Bilophila wadsworthia isolated from surgical specimens].
Topics: Anti-Bacterial Agents; beta-Lactams; Bilophila; Ciprofloxacin; Clindamycin; Digestive System Surgica | 2006 |
Prophylaxis of postoperative endophthalmitis.
Topics: Administration, Topical; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract E | 2007 |
Postoperative endophthalmitis caused by Bacillus cereus and Chlamydia trachomatis.
Topics: Administration, Oral; Administration, Topical; Aged; Anti-Bacterial Agents; Bacillus cereus; Bacteri | 2007 |
Post-LASIK epithelial dendritic defect associated with Alternaria.
Topics: Alternaria; Amphotericin B; Antifungal Agents; Combined Modality Therapy; Corneal Ulcer; Debridement | 2007 |
Fatal hypoglycemia with levofloxacin use in an elderly patient in the post-operative period.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Duodenal Ulcer; Fatal O | 2008 |
[Ultrasound-controlled percutaneous drainage of subhepatic liver abscess after conventional cholecystectomy].
Topics: Aged; Cholecystectomy; Cholecystitis; Cholelithiasis; Combined Modality Therapy; Drainage; Humans; L | 1993 |
An audit of ciprofloxacin use in a district general hospital.
Topics: Anti-Infective Agents; Bacterial Infections; Cephalosporins; Ciprofloxacin; Cross Infection; Drug Ut | 1995 |
[Ten-year experience with the use of ofloxacin in reconstructive surgery].
Topics: Administration, Oral; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Drug Administra | 1996 |
Ofloxacin penetration into the eye after intravenous and topical administration.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiot | 1997 |
Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient.
Topics: Clarithromycin; Drug Therapy, Combination; Ethambutol; Foot; Humans; Kidney Transplantation; Male; M | 1999 |
Tuberculosis in orthotopic liver transplant patients: increased toxicity of recommended agents; cure of disseminated infection with nonconventional regimens.
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combinatio | 2000 |
[Clinical experience with the preparation Uniflox Unimed Pharma in ophthalmology].
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Eye Infections; Humans; Infant; O | 2000 |
Rhodococcus equi and cytomegalovirus pneumonia in a renal transplant patient: diagnosis by fine-needle aspiration biopsy.
Topics: Actinomycetales Infections; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antigens, Viral; An | 2001 |
[Recurrent abscesses in a renal transplant recipient].
Topics: Abscess; Drug Therapy, Combination; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney | 2001 |
Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate.
Topics: Aged; Anti-Infective Agents; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Postoperative Compli | 2001 |
Efficacy of a new quinolone, levofloxacin in patients with surgical infections.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Female; Humans; Levofloxacin; Male; Middle Age | 1992 |
Postoperative osteomyelitis due to Mycobacterium fortuitum. A case report.
Topics: Adolescent; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Fracture Fi | 1992 |
[Ofloxacin and metronidazole in short-term prophylaxis of septic complications after hepatocholedochal surgery].
Topics: Aged; Aged, 80 and over; Biliary Tract Surgical Procedures; Drug Therapy, Combination; Female; Human | 1989 |
Serum and prostatic tissue concentrations of ofloxacin.
Topics: Administration, Oral; Aged; Aged, 80 and over; Half-Life; Humans; Male; Middle Aged; Ofloxacin; Post | 1988 |
Diffusion of ofloxacin in human tissues.
Topics: Administration, Oral; Adult; Female; Humans; Lung Diseases; Male; Middle Aged; Nephrectomy; Ofloxaci | 1987 |