ofloxacin has been researched along with Pneumonia, Staphylococcal in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Pneumonia, Staphylococcal: Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levofloxacin was administered as an infusion of 500 mg/h for 1." | 2.71 | Relationship between fluoroquinolone area under the curve: minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia. ( Corrado, M; Drusano, GL; Fowler, C; Kahn, J; Preston, SL; Weisinger, B, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stefani, S | 1 |
| Bongiorno, D | 1 |
| Cafiso, V | 1 |
| Campanile, F | 1 |
| Crapis, M | 1 |
| Cristini, F | 1 |
| Sartor, A | 1 |
| Scarparo, C | 1 |
| Spina, D | 1 |
| Viale, P | 1 |
| Paleiron, N | 1 |
| Nguyen, BV | 1 |
| Commandeur, D | 1 |
| Danguy des Déserts, M | 1 |
| Rioualen, S | 1 |
| Ralec, B | 1 |
| André, M | 1 |
| Ould-Ahmed, M | 1 |
| Rousset, J | 1 |
| West, M | 1 |
| Boulanger, BR | 1 |
| Fogarty, C | 1 |
| Tennenberg, A | 1 |
| Wiesinger, B | 1 |
| Oross, M | 1 |
| Wu, SC | 1 |
| Fowler, C | 2 |
| Morgan, N | 1 |
| Kahn, JB | 1 |
| Drusano, GL | 1 |
| Preston, SL | 1 |
| Corrado, M | 1 |
| Weisinger, B | 1 |
| Kahn, J | 1 |
| Bouhaja, B | 1 |
| Thabet, H | 1 |
| Slim, L | 1 |
| Aissa, F | 1 |
| Amamou, M | 1 |
| Yacoub, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Open Label Study to Compare the Safety and Efficacy of Levofloxacin With That of Imipenem/Cilastatin in the Treatment of Nosocomial Pneumonia[NCT00236834] | Phase 3 | 438 participants (Actual) | Interventional | 1997-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ofloxacin and Pneumonia, Staphylococcal
| Article | Year |
|---|---|
Levofloxacin compared with imipenem/cilastatin followed by ciprofloxacin in adult patients with nosocomial pneumonia: a multicenter, prospective, randomized, open-label study.
Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Ciprofloxacin; Cross Infection; Drug Therapy, Combin | 2003 |
Relationship between fluoroquinolone area under the curve: minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Area Under Curve; Cross Infection; Female; Fl | 2004 |
3 other studies available for ofloxacin and Pneumonia, Staphylococcal
| Article | Year |
|---|---|
Pathotype and susceptibility profile of a community-acquired methicillin-resistant Staphylococcus aureus strain responsible for a case of severe pneumonia.
Topics: Adult; Bacterial Proteins; Bacterial Toxins; Community-Acquired Infections; DNA Primers; Exotoxins; | 2009 |
[Miliary X-ray pattern is not always related to tuberculosis].
Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Combined Modality Therapy; Device Remov | 2013 |
[Mixte community-acquired Legionella pneumophila and Staphylococcus aureus pneumonia].
Topics: Adult; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Legionnaires' Disea | 1993 |