ofloxacin has been researched along with Pleural Effusion in 9 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ofloxacin (OFLX) concentration in serum, saliva and pleural effusion was measured in 12 patients with pleural effusion after oral administration at a dose of 200 mg three times a day (600 mg daily)." | 7.69 | Ofloxacin concentrations in serum, saliva and pleural effusion of patients with pulmonary tuberculosis and lung cancer. ( Goya, T; Hamakubo, S; Hanaoka, T; Hosaka, K; Miya, T, 1995) |
| "After 3 days of treatment with ofloxacin (300 mg given orally once daily), the drug levels in serum and pleural fluid 2 and 4 h after drug administration in patients with tuberculous pleural effusion were assessed by a rapid high-performance liquid chromatography assay." | 7.68 | Ofloxacin penetration into tuberculous pleural effusion. ( Chan, CY; Cheung, SW; Kwan, SY; Lee, J; Wong, PC; Yew, WW, 1991) |
| "We report a rare case of tuberculous pleurisy with a rapid decrease in pleural effusion by levofloxacin." | 3.74 | [A case of tuberculous pleurisy with a rapid decrease in pleural effusion]. ( Eiji, S; Isowa, N; Kawasaki, Y; Okazaki, R; Tokuyasu, H; Touge, H; Watanabe, E, 2007) |
| "The ofloxacin (OFLX) concentration in serum, saliva and pleural effusion was measured in 12 patients with pleural effusion after oral administration at a dose of 200 mg three times a day (600 mg daily)." | 3.69 | Ofloxacin concentrations in serum, saliva and pleural effusion of patients with pulmonary tuberculosis and lung cancer. ( Goya, T; Hamakubo, S; Hanaoka, T; Hosaka, K; Miya, T, 1995) |
| "After 3 days of treatment with ofloxacin (300 mg given orally once daily), the drug levels in serum and pleural fluid 2 and 4 h after drug administration in patients with tuberculous pleural effusion were assessed by a rapid high-performance liquid chromatography assay." | 3.68 | Ofloxacin penetration into tuberculous pleural effusion. ( Chan, CY; Cheung, SW; Kwan, SY; Lee, J; Wong, PC; Yew, WW, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fenoll, A | 1 |
| Aguilar, L | 1 |
| Vicioso, MD | 1 |
| Gimenez, MJ | 1 |
| Robledo, O | 1 |
| Granizo, JJ | 1 |
| Mendez, C | 1 |
| Liapakis, IE | 1 |
| Kottakis, I | 1 |
| Tzatzarakis, MN | 1 |
| Tsatsakis, AM | 1 |
| Pitiakoudis, MS | 1 |
| Ypsilantis, P | 1 |
| Light, RW | 1 |
| Simopoulos, CE | 1 |
| Bouros, DE | 1 |
| Miglioli, PA | 1 |
| Sartore, P | 1 |
| Gianfranceschi, L | 1 |
| Lanzafame, P | 1 |
| Berti, T | 1 |
| Oznur, AK | 1 |
| Ozer, S | 1 |
| Benzonana, NA | 1 |
| Tokuyasu, H | 1 |
| Watanabe, E | 1 |
| Okazaki, R | 1 |
| Touge, H | 1 |
| Kawasaki, Y | 1 |
| Isowa, N | 1 |
| Eiji, S | 1 |
| Elliott, AM | 1 |
| Berning, SE | 1 |
| Iseman, MD | 1 |
| Peloquin, CA | 1 |
| Miya, T | 1 |
| Hamakubo, S | 1 |
| Goya, T | 1 |
| Hanaoka, T | 1 |
| Hosaka, K | 1 |
| Yew, WW | 1 |
| Lee, J | 1 |
| Chan, CY | 1 |
| Cheung, SW | 1 |
| Wong, PC | 1 |
| Kwan, SY | 1 |
| Warlich, R | 1 |
| Mutschler, E | 1 |
9 other studies available for ofloxacin and Pleural Effusion
| Article | Year |
|---|---|
Serotype distribution and susceptibility of Streptococcus pneumoniae isolates from pleural fluid in Spain from 1997 to 2008.
Topics: Adolescent; Adult; Body Fluids; Cefotaxime; Humans; In Vitro Techniques; Ofloxacin; Penicillins; Ple | 2010 |
Penetration of newer quinolones in the empyema fluid.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Empyema, Pleural; Escherichia coli Infections; Fluoro | 2004 |
Enhancement of antibacterial activity of norfloxacin and ofloxacin in vitro by serum and experimental pleural exudates.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Escherichia coli; Humans; Microbial Sensitivity Tests; Nor | 1989 |
[Antibiotic resistance in Streptococcus pneumoniae strains isolated from sterile body sites].
Topics: Anti-Bacterial Agents; Bacteremia; Cerebrospinal Fluid; Dacryocystitis; Drug Resistance, Bacterial; | 2006 |
[A case of tuberculous pleurisy with a rapid decrease in pleural effusion].
Topics: Aged; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Ofloxacin; Pleural Effusion; Tuberculosis | 2007 |
Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema.
Topics: Aged; Antitubercular Agents; Chronic Disease; Empyema, Tuberculous; Ethambutol; Humans; Male; Ofloxa | 1995 |
Ofloxacin concentrations in serum, saliva and pleural effusion of patients with pulmonary tuberculosis and lung cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Carcinoma, Non-Small-Ce | 1995 |
Ofloxacin penetration into tuberculous pleural effusion.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Mycobacterium tuberc | 1991 |
Thin-layer chromatographic separation and in situ fluorimetric determination of ofloxacin in plasma and pleural fluid.
Topics: Chromatography, Thin Layer; Humans; Ofloxacin; Pleural Effusion; Spectrometry, Fluorescence | 1989 |