ofloxacin has been researched along with Periodontal Diseases in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Four different sites were randomly selected in each periodontal patient and divided into four group: PT-01-treated site (A), PT-01 treatment combined with scaling (S + A), placebo-treated site (P) and placebo treatment combined with scaling (S + P)." | 2.66 | [Effectiveness of local delivery of ofloxacin using controlled-release strips (PT-01) in periodontal patients. Part 2. Successive delivery system and combination with scaling]. ( Fukui, M; Hashizume, A; Ikeda, Y; Kobayashi, R; Ogata, C; Ohno, S; Tanaka, S; Teranishi, Y; Ueda, M; Yamamoto, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alou, L | 1 |
| Giménez, MJ | 1 |
| Manso, F | 1 |
| Sevillano, D | 1 |
| Cafini, F | 1 |
| Torrico, M | 1 |
| González, N | 1 |
| Prieto, J | 1 |
| Alió, JJ | 1 |
| Aguilar, L | 1 |
| Jamal, T | 1 |
| Rahman, MA | 1 |
| Mirza, MA | 1 |
| Panda, AK | 1 |
| Talegaonkar, S | 1 |
| Iqbal, Z | 1 |
| Ishikawa, I | 1 |
| Umeda, M | 1 |
| Laosrisin, N | 1 |
| Mikx, FH | 1 |
| Langendijk, P | 1 |
| Renggli, HH | 1 |
| Takamori, A | 2 |
| Ueda, M | 2 |
| Teranishi, Y | 2 |
| Kitamura, T | 1 |
| Makigusa, K | 1 |
| Shirai, T | 1 |
| Tanaka, M | 1 |
| Higashi, K | 1 |
| Ohashi, S | 1 |
| Minamibayashi, S | 1 |
| Yamaoka, A | 1 |
| Hashizume, A | 1 |
| Yamamoto, M | 1 |
| Ohno, S | 1 |
| Ogata, C | 1 |
| Kobayashi, R | 1 |
| Tanaka, S | 1 |
| Fukui, M | 1 |
| Ikeda, Y | 1 |
| Miyake, Y | 1 |
| Onoe, T | 1 |
| Sagawa, H | 1 |
| Suginaka, H | 1 |
2 trials available for ofloxacin and Periodontal Diseases
| Article | Year |
|---|---|
[Effectiveness of local delivery of ofloxacin using controlled-release strips (PT-01) in periodontal patients. Part 1. PT-01 application among treatment plans for periodontal disease].
Topics: Delayed-Action Preparations; Dental Scaling; Humans; Ofloxacin; Periodontal Diseases; Tooth Root | 1989 |
[Effectiveness of local delivery of ofloxacin using controlled-release strips (PT-01) in periodontal patients. Part 2. Successive delivery system and combination with scaling].
Topics: Delayed-Action Preparations; Dental Prophylaxis; Dental Scaling; Humans; Ofloxacin; Periodontal Dise | 1989 |
6 other studies available for ofloxacin and Periodontal Diseases
| Article | Year |
|---|---|
In vitro killing activity of crevicular concentrations of tinidazole plus common oral antibiotics against high-density mixed inocula of periodontal pathogens in strict anaerobic conditions.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Clavulanic Acid; Clindamycin; Drug Synergis | 2010 |
Formulation, antimicrobial and toxicity evaluation of bioceramic based ofloxacin loaded biodegradable microspheres for periodontal infection.
Topics: Animals; Anti-Bacterial Agents; Cell Survival; Chemistry, Pharmaceutical; Escherichia coli; Escheric | 2012 |
Clinical, bacteriological, and immunological examinations and the treatment process of two Papillon-Lefèvre syndrome patients.
Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Child; Child, Preschool; Colony Count, Mi | 1994 |
[Antibiotic use in periodontics. Results from a research study].
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Clindamycin; Dental Plaque; Doxycycline; Drug Resistan | 1996 |
[Attempt of periodontal chemotherapy by topical application of Ofloxacin].
Topics: Administration, Topical; Humans; Ofloxacin; Periodontal Diseases | 1989 |
In vitro antibacterial activity of ofloxacin against periodontal disease-associated bacteria.
Topics: Bacteria; Microbial Sensitivity Tests; Ofloxacin; Oxazines; Periodontal Diseases | 1988 |