ofloxacin has been researched along with Perforated Appendicitis in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a rare case of spontaneous bilateral Achilles tendon rupture induced by levofloxacin, one of the fluoroquinolone antibiotics." | 8.82 | Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature. ( Amano, M; Kowatari, K; Nakashima, K; Ono, A; Toh, S; Yoshihara, M, 2004) |
| "We present a rare case of spontaneous bilateral Achilles tendon rupture induced by levofloxacin, one of the fluoroquinolone antibiotics." | 4.82 | Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature. ( Amano, M; Kowatari, K; Nakashima, K; Ono, A; Toh, S; Yoshihara, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kowatari, K | 1 |
| Nakashima, K | 1 |
| Ono, A | 1 |
| Yoshihara, M | 1 |
| Amano, M | 1 |
| Toh, S | 1 |
| Taylor, E | 1 |
| Berjis, A | 1 |
| Bosch, T | 1 |
| Hoehne, F | 1 |
| Ozaeta, M | 1 |
| Eriksson, S | 1 |
| Granström, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis (Randomized, Controlled Clinical Trial)[NCT01115153] | 150 participants (Actual) | Interventional | 2007-12-31 | Completed | |||
| Randomized Study of Conservative Versus Surgical Treatment of Appendicitis; Analyses of Result and Economics[NCT00469430] | Phase 2 | 360 participants (Actual) | Interventional | 2006-05-31 | Completed | ||
| Non Operative Treatment for Acute Appendicitis: Study on Efficacy and Safety of Antibiotic Treatment (Amoxicillin and Clavulanic Acid) in Patients With Right Sided Lower Abdominal Pain[NCT01096927] | Phase 4 | 160 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| A Prospective Non-randomized Controlled, Multicenter, Multidisciplinary Trial Comparing Appendectomy and Conservative Treatment for Patients With Uncomplicated Acute Appendicitis (the ACTUAA STUDY).[NCT03080103] | 300 participants (Actual) | Observational | 2017-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ofloxacin and Perforated Appendicitis
| Article | Year |
|---|---|
Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature.
Topics: Achilles Tendon; Aged; Anti-Infective Agents; Appendicitis; Humans; Levofloxacin; Male; Ofloxacin; R | 2004 |
2 trials available for ofloxacin and Perforated Appendicitis
| Article | Year |
|---|---|
The efficacy of postoperative oral antibiotics in appendicitis: a randomized prospective double-blinded study.
Topics: Abdominal Abscess; Acute Disease; Administration, Oral; Adolescent; Adult; Ambulatory Care; Amoxicil | 2004 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |
Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Appendicitis; Cefotaxime; Female; Humans; Male; Middle Aged; | 1995 |