Page last updated: 2024-11-01

ofloxacin and Paratyphoid Fever

ofloxacin has been researched along with Paratyphoid Fever in 8 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Paratyphoid Fever: A prolonged febrile illness commonly caused by several Paratyphi serotypes of SALMONELLA ENTERICA. It is similar to TYPHOID FEVER but less severe.

Research Excerpts

ExcerptRelevanceReference
"In the present study, 33 adult patients with salmonella infections consisting of 13 typhoid fever, 9 paratyphoid fever, 8 enterocolitis, 2 carriers, 1 acute gastroenteritis have been treated with ofloxacin."3.68[Ofloxacin treatment of salmonella infections]. ( Altay, G; Arman, D; Unlü, S, 1993)
"Typhoid and paratyphoid (enteric fever) are febrile bacterial illnesses common in many low- and middle-income countries."2.82Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins. ( Basnyat, B; Darton, TC; Eyre, D; Kuehn, R; Parry, CM; Stoesser, N, 2022)
"Ofloxacin was also effective in the treatment of enteric fever, in which eradication was achieved in all seven patients."2.66Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections. ( Sahaphong, S; Srimuang, S; Tanphaichitra, D, 1986)
"210 clinical isolates of typhoid salmonellae, cultivated from blood of patients with typhoid fever (108 strains of Salmonella typhi, 99 strains of Salmonella paratyphi A and three strains of Salmonella paratyphi B) as well as 266 random clinical isolates of Escherichia coli (n = 152), Klebsiella spp."1.27In vitro activity of ofloxacin against 210 clinical isolates of typhoid salmonellae. ( Hannan, A, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Kuehn, R3
Stoesser, N3
Eyre, D3
Darton, TC3
Basnyat, B4
Parry, CM3
Thompson, CN1
Karkey, A1
Dongol, S1
Arjyal, A1
Wolbers, M1
Darton, T1
Farrar, JJ1
Thwaites, GE1
Dolecek, C1
Baker, S1
Truusalu, K1
Kullisaar, T1
Hütt, P1
Mahlapuu, R1
Aunapuu, M1
Arend, A1
Zilmer, M1
Mikelsaar, RH1
Mikelsaar, M1
Randhawa, VS1
Kumar, A1
Saili, A1
Datta, V1
Agrawal, C1
Mehta, G1
Unlü, S1
Arman, D1
Altay, G1
Sabbour, MS1
Osman, LM1
Hannan, A1
Tanphaichitra, D1
Sahaphong, S1
Srimuang, S1

Reviews

1 review available for ofloxacin and Paratyphoid Fever

ArticleYear
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
    The Cochrane database of systematic reviews, 2022, 11-24, Volume: 11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Cefixime; Ceftriaxone

2022

Trials

3 trials available for ofloxacin and Paratyphoid Fever

ArticleYear
Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Jun-01, Volume: 64, Issue:11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Child; Drug Resistance, Multipl

2017
Experience with ofloxacin in enteric fever.
    Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Drug Administration Schedule; Fem

1990
Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxa

1986

Other Studies

4 other studies available for ofloxacin and Paratyphoid Fever

ArticleYear
Immunological, antioxidative, and morphological response in combined treatment of ofloxacin and Lactobacillus fermentum ME-3 probiotic in Salmonella Typhimurium murine model.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2010, Volume: 118, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Cytokines; Disease Models, Animal; Glutathione Peroxidase; Glutathio

2010
Paratyphoid sepsis.
    Indian journal of pediatrics, 2007, Volume: 74, Issue:2

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Bottle Feeding; Breast Feeding; Cesarean Section; Female; Fo

2007
[Ofloxacin treatment of salmonella infections].
    Mikrobiyoloji bulteni, 1993, Volume: 27, Issue:3

    Topics: Carrier State; Humans; Ofloxacin; Paratyphoid Fever; Salmonella Food Poisoning; Salmonella Infection

1993
In vitro activity of ofloxacin against 210 clinical isolates of typhoid salmonellae.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Anti-Bacterial Agents; Humans; Ofloxacin; Oxazines; Paratyphoid Fever; Salmonella; Salmonella paraty

1986