Page last updated: 2024-11-01

ofloxacin and Ovarian Neoplasms

ofloxacin has been researched along with Ovarian Neoplasms in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Not only in melanoma, but also in MCF7 breast carcinoma and A2780 ovarian carcinoma cells overexpressing MdmX."1.46A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein. ( Growkova, K; Mlcochova, J; Radova, L; Slaby, O; Stetkova, M; Uldrijan, S; Valcikova, B; Valianatos, G; Verlande, A; Vyhnakova, M, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valianatos, G1
Valcikova, B1
Growkova, K1
Verlande, A1
Mlcochova, J1
Radova, L1
Stetkova, M1
Vyhnakova, M1
Slaby, O1
Uldrijan, S1
Park, Y1
Liu, Y1
Hong, J1
Lee, CO1
Cho, H1
Kim, DK1
Im, KS1
Jung, JH1

Other Studies

2 other studies available for ofloxacin and Ovarian Neoplasms

ArticleYear
A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Alternative Splicing; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Damage;

2017
New bromotyrosine derivatives from an association of two sponges, Jaspis wondoensis and Poecillastra wondoensis.
    Journal of natural products, 2003, Volume: 66, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Central Nervous System Neoplasms; Colonic Neoplasms; Dis

2003