ofloxacin has been researched along with Opportunistic Infections in 13 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors analyzed 27 breakthrough bacteremias occurring during ofloxacin prophylaxis in afebrile neutropenia over 7 years in 9989 admissions and 979 bacteremic and fungemic episodes in a National Cancer Center in Bratislava, Slovak Republic." | 7.69 | Bacteremia and fungemia occurring during antimicrobial prophylaxis with ofloxacin in cancer patients: risk factors, etiology and outcome. ( Demitrovicova, A; Drgona, L; Helpianska, L; Ilavska, I; Koren, P; Krcmery, V; Kukuckova, E; Lacka, J; Oravcova, E; Pichna, P; Rusnakova, V; Spanik, S; Studena, M; Trupl, J, 1996) |
| "Bacteremia was documented in two patients in the O+R group and six in the control group (p=0." | 5.30 | Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma. ( Brunet, S; Martino, R; Muñoz, L; Sierra, J; Subirà, M; Sureda, A, 1999) |
| " We conducted a prospective non-randomised trial to evaluate the efficacy of administration of oral ofloxacin by caregivers to paediatric cancer patients with fever and neutropenia." | 5.08 | Out-patient management of febrile neutropenia in indigent paediatric patients. ( Malik, IA, 1997) |
| "The authors analyzed 27 breakthrough bacteremias occurring during ofloxacin prophylaxis in afebrile neutropenia over 7 years in 9989 admissions and 979 bacteremic and fungemic episodes in a National Cancer Center in Bratislava, Slovak Republic." | 3.69 | Bacteremia and fungemia occurring during antimicrobial prophylaxis with ofloxacin in cancer patients: risk factors, etiology and outcome. ( Demitrovicova, A; Drgona, L; Helpianska, L; Ilavska, I; Koren, P; Krcmery, V; Kukuckova, E; Lacka, J; Oravcova, E; Pichna, P; Rusnakova, V; Spanik, S; Studena, M; Trupl, J, 1996) |
| "A 55 year-old male patient with chronic renal failure was hospitalized in intensive care unit following cardiopulmonary arrest." | 1.38 | [A case of ventilator-associated pneumonia due to Pantoea agglomerans]. ( Altın, N; Argun, C; Canbakan, B; Cesur, S; Koldaş, K; Kurşun, O; Sencan, I; Unal, N, 2012) |
| "Cellulitis is usually caused by organisms such as beta-hemolytic streptococci and Staphylococcus aureus." | 1.32 | Sepsis in a renal transplant recipient due to Citrobacter braakii. ( Agraharkar, ML; Gupta, R; Rauf, SJ; Singh, S; Smith, J, 2003) |
| "Bacteremia was documented in two patients in the O+R group and six in the control group (p=0." | 1.30 | Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma. ( Brunet, S; Martino, R; Muñoz, L; Sierra, J; Subirà, M; Sureda, A, 1999) |
| "HIV infection due to intravenous drug abuse had been diagnosed in 1986." | 1.28 | [Reversible space-occupying lesions of the kidney in HIV infection]. ( Bogner, JR; Middeke, M; Zoller, WG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurşun, O | 1 |
| Unal, N | 1 |
| Cesur, S | 1 |
| Altın, N | 1 |
| Canbakan, B | 1 |
| Argun, C | 1 |
| Koldaş, K | 1 |
| Sencan, I | 1 |
| Gracia Escudero, A | 1 |
| Martín González, M | 1 |
| Giménez Garrido, F | 1 |
| Clavero Farré, C | 1 |
| García Pérez, MJ | 1 |
| Alvarez Corral, G | 1 |
| Reyes Bertos, A | 1 |
| Villegas Maldonado, G | 1 |
| Rodríguez Cuartero, A | 1 |
| Gupta, R | 1 |
| Rauf, SJ | 1 |
| Singh, S | 1 |
| Smith, J | 1 |
| Agraharkar, ML | 1 |
| Watson, AM | 1 |
| Boyce, TG | 1 |
| Wylam, ME | 1 |
| Chou, SY | 1 |
| Tsai, CC | 1 |
| Kau, SC | 1 |
| Kau, HC | 1 |
| Hsu, WM | 1 |
| Roveta, S | 1 |
| Schito, AM | 1 |
| Marchese, A | 1 |
| Schito, GC | 1 |
| Upton, C | 1 |
| Spanik, S | 1 |
| Trupl, J | 1 |
| Ilavska, I | 1 |
| Helpianska, L | 1 |
| Drgona, L | 1 |
| Demitrovicova, A | 1 |
| Kukuckova, E | 1 |
| Studena, M | 1 |
| Pichna, P | 1 |
| Oravcova, E | 1 |
| Rusnakova, V | 1 |
| Koren, P | 1 |
| Lacka, J | 1 |
| Krcmery, V | 1 |
| Malik, IA | 1 |
| Muñoz, L | 1 |
| Martino, R | 1 |
| Subirà, M | 1 |
| Brunet, S | 1 |
| Sureda, A | 1 |
| Sierra, J | 1 |
| Del Pozo, JL | 1 |
| Lecároz, C | 1 |
| Hernáez, S | 1 |
| Leiva, J | 1 |
| Ballester, B | 1 |
| Valero, E | 1 |
| Sevillano, D | 1 |
| Calvo, A | 1 |
| García, R | 1 |
| Leturia, A | 1 |
| Gómez-Lus, ML | 1 |
| Bogner, JR | 1 |
| Zoller, WG | 1 |
| Middeke, M | 1 |
2 trials available for ofloxacin and Opportunistic Infections
| Article | Year |
|---|---|
[A prospective, controlled, non-randomized study of three cohorts to test the effectiveness of two antibiotics levofloxacin and cotrimoxazol on antibacterial prophylaxis in neutropenic patients].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Humans; Leukemia; Levofloxac | 2003 |
Out-patient management of febrile neutropenia in indigent paediatric patients.
Topics: Administration, Oral; Adolescent; Ambulatory Care; Anti-Infective Agents; Child; Child, Preschool; F | 1997 |
11 other studies available for ofloxacin and Opportunistic Infections
| Article | Year |
|---|---|
[A case of ventilator-associated pneumonia due to Pantoea agglomerans].
Topics: Anti-Bacterial Agents; Cefoperazone; Cross Infection; Drug Therapy, Combination; Enterobacteriaceae | 2012 |
Sepsis in a renal transplant recipient due to Citrobacter braakii.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Bacteremia; Cellulitis; Citrobacter freundi | 2003 |
Legionella pneumonia: infection during immunosuppressive therapy for idiopathic pulmonary hemosiderosis.
Topics: Child; Drug Therapy, Combination; Female; Follow-Up Studies; Hemosiderosis; Humans; Immunosuppressiv | 2004 |
Aeromonas hydrophila orbital cellulitis in a patient with myelodysplastic syndrome.
Topics: Aeromonas hydrophila; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Cellulitis; Gr | 2004 |
Microbiological rationale for the utilisation of prulifloxacin, a new fluoroquinolone, in the eradication of serious infections caused by Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cystic Fibrosis; Dioxolanes; Drug Resistance, B | 2005 |
Sleep disturbance in children treated with ofloxacin.
Topics: Child; Cystic Fibrosis; Female; Humans; Male; Ofloxacin; Opportunistic Infections; Pseudomonas Infec | 1994 |
Bacteremia and fungemia occurring during antimicrobial prophylaxis with ofloxacin in cancer patients: risk factors, etiology and outcome.
Topics: Bacteremia; Disease Outbreaks; Fungemia; Humans; Incidence; Microbial Sensitivity Tests; Neoplasms; | 1996 |
Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bact | 1999 |
[Recurrent abscesses in a renal transplant recipient].
Topics: Abscess; Drug Therapy, Combination; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney | 2001 |
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].
Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; | 2001 |
[Reversible space-occupying lesions of the kidney in HIV infection].
Topics: Abscess; Adult; Cefuroxime; Female; HIV Infections; Humans; Nephritis; Ofloxacin; Opportunistic Infe | 1990 |