ofloxacin has been researched along with Neisseria gonorrhoeae Infection in 67 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of gonorrhea is complicated by widespread resistance of Neisseria gonorrhoeae to antimicrobial agents of choice, including decreased susceptibility to ciprofloxacin." | 9.09 | Single-dose gatifloxacin compared with ofloxacin for the treatment of uncomplicated gonorrhea: a randomized, double-blind, multicenter trial. ( Baumgartner, T; Douglas, JM; Hook, EW; Jones, R; Leone, P; Martin, DH; McCormack, WM; Mroczkowski, TF; Stoner, BP; Yang, J, 2001) |
| " Patients identified with laparoscopic findings of salpingitis were treated with 400 mg of intravenous ofloxacin every 12 hours followed by 400 mg of oral ofloxacin every 12 hours for 10 to 14 days." | 9.09 | Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis). ( Kahn, J; Peipert, JF; Rielly-Gauvin, K; Sweet, RL; Walker, CK, 1999) |
| "To compare trovafloxacin, a new quinolone antibiotic with enhanced activity against Neisseria gonorrhoeae, with ofloxacin as single-dose oral therapy for uncomplicated gonococcal urethritis or cervicitis." | 9.08 | Randomized trial of trovafloxacin and ofloxacin for single-dose therapy of gonorrhea. Trovafloxacin Gonorrhea Study Group. ( Dalu, ZA; Johnson, RB; Jones, RB; Leone, P; Schwebke, J; Thorpe, EM, 1998) |
| "A multicenter randomized comparative trial was done to assess the safety and efficacy of oral ofloxacin (400 mg twice daily for 10 days) versus cefoxitin (2 g intramuscularly) followed by doxycycline (100 mg twice daily orally for 10 days) for the outpatient treatment of uncomplicated pelvic inflammatory disease (PID)." | 9.07 | Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group. ( Berkeley, A; Binder, D; Faro, S; Gordon, S; Martens, MG; Yarborough, DR, 1993) |
| "The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis." | 9.07 | A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991) |
| "Efficacy and safety of ofloxacin (OFLX), a new quinolone antibacterial agent, were investigated in cases of sexually transmitted male urethritis and cervicitis." | 9.06 | [Efficacy of ofloxacin in sexually transmitted male urethritis and cervicitis]. ( Aso, Y; Higashihara, E; Hirose, T; Kishi, H; Kiyota, H; Kumamoto, Y; Machida, T; Okazaki, T; Sakai, S; Tsunekawa, T, 1988) |
| "Two multicenter trials compared single-dose oral therapy with 400 mg of ofloxacin or 3 g of amoxicillin plus 1 g of probenecid in the treatment of uncomplicated gonorrhea in 160 men and 102 women." | 9.06 | Single-dose efficacy of ofloxacin in uncomplicated gonorrhea. ( Lutz, FB, 1989) |
| "We attempted to define the microbiologic characteristics of acute salpingitis in women presenting to an urban emergency department with pelvic inflammatory disease and to determine the effectiveness of ofloxacin in treating this disease." | 7.68 | Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin. ( Brockwell, NJ; Dalton, HP; Soper, DE, 1992) |
| "Ofloxacin was used in the treatment of 20 cases of typhoid fever, 32 cases of bacillary dysentery and 50 cases of gonococcal infection." | 7.68 | [Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea]. ( Jiang, YF; Wang, QN; Zou, QY, 1991) |
| "We performed basic and clinical studies in male gonococcal urethritis on a new oral antimicrobial agent, levofloxacin (LVFX, DR-3355), a new quinolone derivative." | 7.68 | [Bacteriological and clinical studies on levofloxacin in male gonococcal urethritis]. ( Ono, K; Saiko, Y; Saito, I; Suzuki, A; Yokozawa, M, 1992) |
| "A multi-institutional clinical study was performed on the efficacy of Ofloxacin against chlamydial urethritis in males between January and June, 1987." | 7.67 | [Studies of clinical efficacy of ofloxacin against male urethritis caused by Chlamydia trachomatis]. ( Matsuda, T; Okada, K; Yoshida, O, 1988) |
| "Ofloxacin is a new fluoroquinolone with in vitro activity against the three main urethritis-causing pathogens: i." | 7.67 | [Treatment with ofloxacin (RU 43280) of uncomplicated bacterial urethritis in males]. ( Bianchi, A; Casin, I; Dolivo, M; Morel, P; Perol, Y, 1986) |
| "Sexually transmitted diseases are an important cause of morbidity in women." | 6.38 | The clinical experience with ofloxacin in the treatment of sexually transmitted diseases. ( Corrado, ML, 1991) |
| "Ofloxacin is a new fluoroquinolone with excellent in vitro activity against N." | 5.27 | [One-dose treatment of male gonococcal urethritis by ofloxacin]. ( Baury, A; Casin, I; Lassau, F; Morel, P; Perol, Y, 1987) |
| " Patients identified with laparoscopic findings of salpingitis were treated with 400 mg of intravenous ofloxacin every 12 hours followed by 400 mg of oral ofloxacin every 12 hours for 10 to 14 days." | 5.09 | Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis). ( Kahn, J; Peipert, JF; Rielly-Gauvin, K; Sweet, RL; Walker, CK, 1999) |
| "Treatment of gonorrhea is complicated by widespread resistance of Neisseria gonorrhoeae to antimicrobial agents of choice, including decreased susceptibility to ciprofloxacin." | 5.09 | Single-dose gatifloxacin compared with ofloxacin for the treatment of uncomplicated gonorrhea: a randomized, double-blind, multicenter trial. ( Baumgartner, T; Douglas, JM; Hook, EW; Jones, R; Leone, P; Martin, DH; McCormack, WM; Mroczkowski, TF; Stoner, BP; Yang, J, 2001) |
| "To compare trovafloxacin, a new quinolone antibiotic with enhanced activity against Neisseria gonorrhoeae, with ofloxacin as single-dose oral therapy for uncomplicated gonococcal urethritis or cervicitis." | 5.08 | Randomized trial of trovafloxacin and ofloxacin for single-dose therapy of gonorrhea. Trovafloxacin Gonorrhea Study Group. ( Dalu, ZA; Johnson, RB; Jones, RB; Leone, P; Schwebke, J; Thorpe, EM, 1998) |
| "The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated acute salpingitis." | 5.07 | A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( Bawdon, RE; Cox, SM; Heard, MC; Nobles, BJ; Theriot, SK; Wendel, GD, 1991) |
| "A multicenter randomized comparative trial was done to assess the safety and efficacy of oral ofloxacin (400 mg twice daily for 10 days) versus cefoxitin (2 g intramuscularly) followed by doxycycline (100 mg twice daily orally for 10 days) for the outpatient treatment of uncomplicated pelvic inflammatory disease (PID)." | 5.07 | Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group. ( Berkeley, A; Binder, D; Faro, S; Gordon, S; Martens, MG; Yarborough, DR, 1993) |
| "Two multicenter trials compared single-dose oral therapy with 400 mg of ofloxacin or 3 g of amoxicillin plus 1 g of probenecid in the treatment of uncomplicated gonorrhea in 160 men and 102 women." | 5.06 | Single-dose efficacy of ofloxacin in uncomplicated gonorrhea. ( Lutz, FB, 1989) |
| "Efficacy and safety of ofloxacin (OFLX), a new quinolone antibacterial agent, were investigated in cases of sexually transmitted male urethritis and cervicitis." | 5.06 | [Efficacy of ofloxacin in sexually transmitted male urethritis and cervicitis]. ( Aso, Y; Higashihara, E; Hirose, T; Kishi, H; Kiyota, H; Kumamoto, Y; Machida, T; Okazaki, T; Sakai, S; Tsunekawa, T, 1988) |
| "The clinical efficacies of 2 different single-dose oral treatments of ofloxacin were evaluated in a double-blind, randomised study of 60 males with gonococcal urethritis." | 5.06 | Single doses of ofloxacin in uncomplicated gonorrhoea. ( Aznar, J; Herrera, A; Perea, EJ; Prados, R; Rodriguez-Pichardo, A, 1987) |
| "Experience with ofloxacin in the United States in the treatment of sexually transmitted diseases is reviewed." | 5.06 | Clinical experience with ofloxacin in sexually transmitted disease. ( Beals, BS; Judson, FN; Tack, KJ, 1986) |
| " All 19 cases of gonoccocal urethritis in the present study were cured with a single intramuscular injection of 2 g spectinomycin." | 3.72 | Frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae in Tokyo in 2002. ( Abe, H; Aoto, T; Nishimura, T; Norose, Y; Ohkuni, H; Ohzuka, H, 2003) |
| "The susceptibilities of 37 penicillinase-producing strains of Neisseria gonorrhoeae (PPNG), isolated in Hawaii from December 1991 through January 1994, were determined to ciprofloxacin and ofloxacin, fluoroquinolone agents currently recommended by the Centers for Disease Control and Prevention as alternative regimens for the treatment of uncomplicated gonorrhea." | 3.69 | Emerging in vitro resistance to quinolones in penicillinase-producing Neisseria gonorrhoeae strains in Hawaii. ( Higa, H; Knapp, JS; Neal, SW; Ohye, R; Parekh, MC; Rice, RJ, 1994) |
| "Treatment failure with multiple doses of ofloxacin was observed in this case of gonorrhea." | 3.69 | Fluoroquinolone treatment failure in gonorrhea. Emergence of a Neisseria gonorrhoeae strain with enhanced resistance to fluoroquinolones. ( Deguchi, K; Deguchi, T; Kanematsu, E; Kawada, Y; Nakano, M; Nishino, Y; Ozeki, S; Saito, I; Sato, K; Tanaka, M; Yasuda, M, 1997) |
| "Ofloxacin was used in the treatment of 20 cases of typhoid fever, 32 cases of bacillary dysentery and 50 cases of gonococcal infection." | 3.68 | [Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea]. ( Jiang, YF; Wang, QN; Zou, QY, 1991) |
| "Results of the treatment of 5 cases of males with uncomplicated gonoccocal urethritis using levofloxacin (LVFX, DR-3355), the L-type optical isomer of ofloxacin (OFLX), were compared with those treated with OFLX itself." | 3.68 | [Treatment of gonococcal urethritis]. ( Katsukawa, C; Makino, M; Osato, K, 1991) |
| "We performed basic and clinical studies in male gonococcal urethritis on a new oral antimicrobial agent, levofloxacin (LVFX, DR-3355), a new quinolone derivative." | 3.68 | [Bacteriological and clinical studies on levofloxacin in male gonococcal urethritis]. ( Ono, K; Saiko, Y; Saito, I; Suzuki, A; Yokozawa, M, 1992) |
| "We attempted to define the microbiologic characteristics of acute salpingitis in women presenting to an urban emergency department with pelvic inflammatory disease and to determine the effectiveness of ofloxacin in treating this disease." | 3.68 | Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin. ( Brockwell, NJ; Dalton, HP; Soper, DE, 1992) |
| "A multi-institutional clinical study was performed on the efficacy of Ofloxacin against chlamydial urethritis in males between January and June, 1987." | 3.67 | [Studies of clinical efficacy of ofloxacin against male urethritis caused by Chlamydia trachomatis]. ( Matsuda, T; Okada, K; Yoshida, O, 1988) |
| "Ofloxacin is a new fluoroquinolone with in vitro activity against the three main urethritis-causing pathogens: i." | 3.67 | [Treatment with ofloxacin (RU 43280) of uncomplicated bacterial urethritis in males]. ( Bianchi, A; Casin, I; Dolivo, M; Morel, P; Perol, Y, 1986) |
| "In a word, both drugs are effective in treating bacterial infections of digestive system, urinary system and respiratory tract." | 2.67 | [Clinical efficacy of ciprofloxacin and ofloxacin]. ( Jiang, SC; Miao, JZ; Wang, XF, 1994) |
| "Ofloxacin was successful in eradicating C." | 2.67 | Effectiveness of ofloxacin in the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae cervical infection. ( Faro, S; Hammill, HA; Maccato, M; Martens, MG; Riddle, G; Roberts, S, 1991) |
| "Gonorrhea, trichomoniasis, chlamydiosis and Ureaplasma infection were detected in 60, 31." | 2.67 | [Ofloxacin and ciprofloxacin in the treatment of sexually-transmitted diseases]. ( Bakalova, LA; Bednova, VN; Bugrov, AV; Kisina, VI; Navolotskaia, TI; Vakhnina, TE, 1992) |
| "Ofloxacin was also effective in the treatment of enteric fever, in which eradication was achieved in all seven patients." | 2.66 | Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections. ( Sahaphong, S; Srimuang, S; Tanphaichitra, D, 1986) |
| " We conclude that a single oral dose of ofloxacin in the studied dosage regimens was highly effective and safe in the treatment of uncomplicated gonorrhoea." | 2.66 | Single dose ofloxacin in treatment of uncomplicated gonorrhoea. ( Chan, AS; Fung, KK; Ng, TK; Tang, KC, 1986) |
| "Sexually transmitted diseases are an important cause of morbidity in women." | 2.38 | The clinical experience with ofloxacin in the treatment of sexually transmitted diseases. ( Corrado, ML, 1991) |
| "Most patients (81%) with pelvic inflammatory disease were diagnosed as having chlamydia alone." | 1.48 | Gonococcal and Chlamydial Cases of Pelvic Inflammatory Disease at 2 Canadian Sexually Transmitted Infection Clinics, 2004 to 2014: A Retrospective Cross-sectional Review. ( Chen, JZ; Gratrix, J; Parker, P; Read, R; Singh, AE; Smyczek, P, 2018) |
| "Gemifloxacin is a valid therapeutic alternative to treat infections with N." | 1.32 | In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene. ( Aguilar, L; Garcia-Mendez, E; Jiménez De Anta, MT; Marco, F; Mensa, J; Ruiz, J; Sierra, JM; Vila, J, 2003) |
| "Ofloxacin was used to treat patients with gonorrhoea and/or Chlamydia trachomatis infection." | 1.27 | The efficacy of ofloxacin against infection caused by Neisseria gonorrhoeae and Chlamydia trachomatis. ( Bhattacharyya, MN; Chowdhury, FH; Maiti, H; Richmond, SJ; Stirland, RM; Tooth, JA, 1988) |
| "Ofloxacin is a new fluoroquinolone with excellent in vitro activity against N." | 1.27 | [One-dose treatment of male gonococcal urethritis by ofloxacin]. ( Baury, A; Casin, I; Lassau, F; Morel, P; Perol, Y, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (25.37) | 18.7374 |
| 1990's | 34 (50.75) | 18.2507 |
| 2000's | 13 (19.40) | 29.6817 |
| 2010's | 3 (4.48) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JZ | 1 |
| Gratrix, J | 1 |
| Smyczek, P | 1 |
| Parker, P | 1 |
| Read, R | 1 |
| Singh, AE | 1 |
| Noguchi, Y | 1 |
| Khalifa, AB | 1 |
| Mastouri, M | 1 |
| Abdallah, HB | 1 |
| Noomen, S | 1 |
| Khedher, M | 1 |
| Ferreira, WA | 1 |
| Ferreira, CM | 1 |
| Naveca, FG | 1 |
| Almeida, NC | 1 |
| Vasconcelos, Wde S | 1 |
| Gomes, Jde S | 1 |
| Silva, Mde F | 1 |
| Alecrim, Md | 1 |
| Bourret, A | 1 |
| Fauconnier, A | 1 |
| Brun, JL | 1 |
| Ruiz, J | 1 |
| Marco, F | 1 |
| Sierra, JM | 1 |
| Aguilar, L | 1 |
| Garcia-Mendez, E | 1 |
| Mensa, J | 1 |
| Jiménez De Anta, MT | 1 |
| Vila, J | 1 |
| Abe, H | 1 |
| Nishimura, T | 1 |
| Norose, Y | 1 |
| Aoto, T | 1 |
| Ohzuka, H | 1 |
| Ohkuni, H | 1 |
| Shigemura, K | 1 |
| Shirakawa, T | 1 |
| Okada, H | 1 |
| Hinata, N | 1 |
| Acharya, B | 1 |
| Kinoshita, S | 1 |
| Kofuku, T | 1 |
| Kawabata, M | 1 |
| Kamidono, S | 1 |
| Arakawa, S | 1 |
| Gotoh, A | 1 |
| Dewi, BE | 1 |
| Akira, S | 1 |
| Hayashi, H | 1 |
| Ba-Thein, W | 1 |
| Komeda, H | 1 |
| Fujimoto, Y | 1 |
| Uno, M | 1 |
| Takada, T | 1 |
| Yamada, Y | 1 |
| Guettrot-Imbert, G | 1 |
| Letranchant, L | 1 |
| Gallot, D | 1 |
| Romaszko, C | 1 |
| Laurichesse, H | 1 |
| Jabeen, K | 1 |
| Khan, E | 1 |
| Hasan, R | 1 |
| Hovhannisyan, G | 1 |
| von Schoen-Angerer, T | 1 |
| Babayan, K | 1 |
| Fenichiu, O | 1 |
| Gaboulaud, V | 1 |
| Yamamoto, Y | 1 |
| Sato, K | 2 |
| Miyazaki, R | 1 |
| Nakai, H | 1 |
| Kam, KM | 4 |
| Lo, KK | 3 |
| Ho, NK | 2 |
| Cheung, MM | 3 |
| Knapp, JS | 3 |
| Washington, JA | 1 |
| Doyle, LJ | 1 |
| Neal, SW | 2 |
| Parekh, MC | 2 |
| Rice, RJ | 2 |
| Ohye, R | 1 |
| Higa, H | 1 |
| Jiang, SC | 1 |
| Wang, XF | 1 |
| Miao, JZ | 1 |
| Loughlin, KA | 1 |
| Bakst, CM | 1 |
| Rybak, MJ | 1 |
| Kuznetsov, VP | 1 |
| Dubenskiĭ, VV | 1 |
| Delektorskiĭ, VV | 1 |
| Igoshin, IuM | 1 |
| Beliaev, DL | 1 |
| Iashkova, GN | 1 |
| Babaiants, AA | 1 |
| Tanaka, M | 4 |
| Kumazawa, J | 1 |
| Matsumoto, T | 1 |
| Kobayashi, I | 3 |
| Lai, CF | 1 |
| Lee, YS | 1 |
| Chan, CB | 1 |
| Bogaerts, J | 1 |
| Tello, WM | 1 |
| Akingeneye, J | 1 |
| Mukantabana, V | 1 |
| Van Dyck, E | 1 |
| Piot, P | 1 |
| Hou, SR | 1 |
| Martens, MG | 2 |
| Gordon, S | 1 |
| Yarborough, DR | 1 |
| Faro, S | 2 |
| Binder, D | 1 |
| Berkeley, A | 1 |
| Aavitsland, P | 1 |
| Høiby, EA | 1 |
| Wong, PW | 1 |
| Deguchi, T | 1 |
| Saito, I | 2 |
| Deguchi, K | 1 |
| Yasuda, M | 1 |
| Nakano, M | 1 |
| Nishino, Y | 1 |
| Kanematsu, E | 1 |
| Ozeki, S | 1 |
| Kawada, Y | 1 |
| Jones, RB | 1 |
| Schwebke, J | 1 |
| Thorpe, EM | 1 |
| Dalu, ZA | 1 |
| Leone, P | 2 |
| Johnson, RB | 1 |
| Chandeying, V | 1 |
| Skov, S | 1 |
| Kemapunmanus, M | 1 |
| Law, M | 1 |
| Geater, A | 1 |
| Rowe, P | 1 |
| Peipert, JF | 1 |
| Sweet, RL | 1 |
| Walker, CK | 1 |
| Kahn, J | 1 |
| Rielly-Gauvin, K | 1 |
| Sagiyama, K | 1 |
| Haraoka, M | 1 |
| Saika, T | 2 |
| Naito, S | 2 |
| Chong, LY | 1 |
| Au, WF | 1 |
| Wong, PY | 1 |
| Tunoe, H | 1 |
| Mochida, O | 1 |
| Kanayama, A | 1 |
| Stoner, BP | 1 |
| Douglas, JM | 1 |
| Martin, DH | 1 |
| Hook, EW | 2 |
| McCormack, WM | 2 |
| Mroczkowski, TF | 1 |
| Jones, R | 1 |
| Yang, J | 1 |
| Baumgartner, T | 1 |
| Otero, L | 1 |
| Alcala, B | 1 |
| Varela, JA | 1 |
| Miguel, MD | 1 |
| Vazquez, JA | 1 |
| Vazquez, F | 1 |
| Bednova, VN | 1 |
| Bakalova, LA | 1 |
| Bugrov, AV | 1 |
| Navolotskaia, TI | 1 |
| Kisina, VI | 1 |
| Vakhnina, TE | 1 |
| Soper, DE | 1 |
| Brockwell, NJ | 1 |
| Dalton, HP | 1 |
| Suzuki, A | 1 |
| Saiko, Y | 1 |
| Yokozawa, M | 1 |
| Ono, K | 1 |
| Addiss, SS | 1 |
| Nakata, S | 1 |
| Miki, M | 1 |
| Okabe, K | 1 |
| Mashimo, T | 1 |
| Kobayashi, M | 1 |
| Yamanaka, H | 1 |
| Takahashi, O | 1 |
| Onuki, T | 1 |
| Osato, K | 1 |
| Katsukawa, C | 1 |
| Makino, M | 1 |
| Zou, QY | 1 |
| Wang, QN | 1 |
| Jiang, YF | 1 |
| Maccato, M | 1 |
| Hammill, HA | 1 |
| Roberts, S | 1 |
| Riddle, G | 1 |
| Wendel, GD | 1 |
| Cox, SM | 1 |
| Bawdon, RE | 1 |
| Theriot, SK | 1 |
| Heard, MC | 1 |
| Nobles, BJ | 1 |
| Corrado, ML | 1 |
| Covino, JM | 1 |
| Cummings, M | 1 |
| Smith, B | 1 |
| Benes, S | 1 |
| Draft, K | 1 |
| Melby, K | 1 |
| Faegri, A | 1 |
| Lutz, FB | 1 |
| Black, JR | 1 |
| Long, JM | 1 |
| Zwickl, BE | 1 |
| Ray, BS | 1 |
| Verdon, MS | 1 |
| Wetherby, S | 1 |
| Handsfield, HH | 1 |
| Heap, BJ | 1 |
| Blomer, R | 1 |
| Bruch, K | 1 |
| Klose, U | 1 |
| Tanphaichitra, D | 1 |
| Sahaphong, S | 1 |
| Srimuang, S | 1 |
| Matsuda, T | 1 |
| Okada, K | 1 |
| Yoshida, O | 1 |
| Kumamoto, Y | 1 |
| Sakai, S | 1 |
| Hirose, T | 1 |
| Tsunekawa, T | 1 |
| Machida, T | 1 |
| Kiyota, H | 1 |
| Okazaki, T | 1 |
| Kishi, H | 1 |
| Higashihara, E | 1 |
| Aso, Y | 1 |
| Richmond, SJ | 1 |
| Bhattacharyya, MN | 1 |
| Maiti, H | 1 |
| Chowdhury, FH | 1 |
| Stirland, RM | 1 |
| Tooth, JA | 1 |
| Morel, P | 2 |
| Lassau, F | 1 |
| Casin, I | 2 |
| Baury, A | 1 |
| Perol, Y | 2 |
| Henderson, A | 1 |
| Aznar, J | 1 |
| Prados, R | 1 |
| Herrera, A | 1 |
| Rodriguez-Pichardo, A | 1 |
| Perea, EJ | 1 |
| Bianchi, A | 1 |
| Dolivo, M | 1 |
| Judson, FN | 1 |
| Beals, BS | 1 |
| Tack, KJ | 1 |
| Ariyarit, C | 1 |
| Panikabutra, K | 1 |
| Chitwarakorn, A | 1 |
| Wongba, C | 1 |
| Buatiang, A | 1 |
| Chan, AS | 1 |
| Tang, KC | 1 |
| Fung, KK | 1 |
| Ng, TK | 1 |
4 reviews available for ofloxacin and Neisseria gonorrhoeae Infection
| Article | Year |
|---|---|
[Pharyngeal Neisseria gonorrhoeae and Chlamydia trachomatis infections].
Topics: Anti-Bacterial Agents; Azithromycin; Bacteriological Techniques; Cephalosporins; Chlamydia Infection | 2009 |
[Management of uncomplicated pelvic inflammatory disease].
Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Chlamydia trachomatis; Drug Resistance, Microbial; | 2012 |
Oral treatment of gonorrhea and chlamydia.
Topics: Administration, Oral; Anti-Infective Agents; Cefixime; Cefotaxime; Chlamydia Infections; Ciprofloxac | 1994 |
The clinical experience with ofloxacin in the treatment of sexually transmitted diseases.
Topics: Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Ofloxacin; Pelvic Inflammato | 1991 |
20 trials available for ofloxacin and Neisseria gonorrhoeae Infection
| Article | Year |
|---|---|
[Clinical efficacy of ciprofloxacin and ofloxacin].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Ciprofloxacin; Dysentery, Bacillary; Female; Gonorrhe | 1994 |
[Clinical study of Chinese ofloxacin].
Topics: Adolescent; Adult; Aged; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxacin; Respiratory Tract | 1993 |
Multicenter randomized trial of ofloxacin versus cefoxitin and doxycycline in outpatient treatment of pelvic inflammatory disease. Ambulatory PID Research Group.
Topics: Adolescent; Adult; Ambulatory Care; Cefoxitin; Chlamydia Infections; Chlamydia trachomatis; Doxycycl | 1993 |
Randomized trial of trovafloxacin and ofloxacin for single-dose therapy of gonorrhea. Trovafloxacin Gonorrhea Study Group.
Topics: Adolescent; Adult; Anti-Infective Agents; Double-Blind Method; Female; Fluoroquinolones; Gonorrhea; | 1998 |
Evaluation of two clinical protocols for the management of women with vaginal discharge in southern Thailand.
Topics: Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Clinical Protocols; Doxycycline; Female; Go | 1998 |
Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis).
Topics: Administration, Oral; Adult; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Dru | 1999 |
Single-dose gatifloxacin compared with ofloxacin for the treatment of uncomplicated gonorrhea: a randomized, double-blind, multicenter trial.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Double-Blind Method; Drug Administra | 2001 |
[Ofloxacin and ciprofloxacin in the treatment of sexually-transmitted diseases].
Topics: Chlamydia Infections; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Female | 1992 |
Effectiveness of ofloxacin in the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae cervical infection.
Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Doxycycline; Drug Evaluation; Female | 1991 |
A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis.
Topics: Acute Disease; Adult; Ambulatory Care; Cefoxitin; Chi-Square Distribution; Chlamydia Infections; Chl | 1991 |
Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains.
Topics: Adult; Ceftriaxone; Chlamydia trachomatis; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Te | 1990 |
Single-dose efficacy of ofloxacin in uncomplicated gonorrhea.
Topics: Adolescent; Adult; Amoxicillin; Ampicillin Resistance; Drug Combinations; Drug Resistance, Microbial | 1989 |
Multicenter randomized study of single-dose ofloxacin versus amoxicillin-probenecid for treatment of uncomplicated gonococcal infection.
Topics: Adult; Amoxicillin; Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Male; Mi | 1989 |
Ofloxacin, a new quinolone in the treatment of genitourinary and enteric infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Female; Gonorrhea; Humans; Male; Middle Aged; Ofloxa | 1986 |
[Efficacy of ofloxacin in sexually transmitted male urethritis and cervicitis].
Topics: Adult; Chlamydia Infections; Chlamydia trachomatis; Drug Evaluation; Female; Gonorrhea; Humans; Male | 1988 |
Low dose oral ofloxacin to treat gonorrhoea in Hong Kong.
Topics: Administration, Oral; Anti-Infective Agents; Clinical Trials as Topic; Gonorrhea; Humans; Male; Oflo | 1987 |
Single doses of ofloxacin in uncomplicated gonorrhoea.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Clinical Trials as Topic; Double-Blind Method; Gonor | 1987 |
Clinical experience with ofloxacin in sexually transmitted disease.
Topics: Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Clinical Trials as Topic; Double | 1986 |
Efficacy of ofloxacin in uncomplicated gonorrhoea.
Topics: Anti-Infective Agents; Clinical Trials as Topic; Double-Blind Method; Gonorrhea; Humans; Male; Oflox | 1986 |
Single dose ofloxacin in treatment of uncomplicated gonorrhoea.
Topics: Adult; Anti-Infective Agents; Clinical Trials as Topic; Female; Gonorrhea; Humans; Male; Ofloxacin; | 1986 |
43 other studies available for ofloxacin and Neisseria gonorrhoeae Infection
| Article | Year |
|---|---|
Gonococcal and Chlamydial Cases of Pelvic Inflammatory Disease at 2 Canadian Sexually Transmitted Infection Clinics, 2004 to 2014: A Retrospective Cross-sectional Review.
Topics: Adolescent; Adult; Ambulatory Care Facilities; Anti-Bacterial Agents; Canada; Chlamydia Infections; | 2018 |
[Male gonococcal infection: antibiotic resistance in the Monastir Teaching Hospital, Tunisia (1999-2003)].
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; O | 2009 |
Genotyping of two Neisseria gonorrhoeae fluroquinolone-resistant strains in the Brazilian Amazon Region.
Topics: Adult; Anti-Bacterial Agents; Brazil; Ciprofloxacin; Drug Resistance, Bacterial; Genotype; Gonorrhea | 2011 |
In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistan | 2003 |
Frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae in Tokyo in 2002.
Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gonorrhea; Huma | 2003 |
Mutations in the gyrA and parC genes and in vitro activities of fluoroquinolones in 91 clinical isolates of Neisseria gonorrhoeae in Japan.
Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; | 2004 |
High occurrence of simultaneous mutations in target enzymes and MtrRCDE efflux system in quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Res | 2004 |
[Clinical study of male urethritis in Oogaki Municipal Hospital].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Chlamydia Infections; Fluoroquinolones; Gonorrhea; Hospita | 2005 |
[Multiorgan failure due to gonococcal peritonitis in an HIV-HCV co-infected female patient].
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Ascites; Bacteremia; Carcinoma, Hepatocellular | 2004 |
Emergence of quinolone-resistant Neisseria gonorrhoeae in Pakistan.
Topics: Adult; Anti-Infective Agents; Communicable Diseases, Emerging; Drug Resistance, Bacterial; Female; G | 2006 |
Antimicrobial susceptibility of Neisseria gonorrheae strains in three regions of Armenia.
Topics: Anti-Bacterial Agents; Armenia; Ciprofloxacin; Doxycycline; Gonorrhea; Humans; Kanamycin; Microbial | 2007 |
[Clinical studies on DL-8280 in male gonococcal urethritis].
Topics: Adult; Anti-Infective Agents; Drug Evaluation; Gonorrhea; Humans; Male; Middle Aged; Ofloxacin; Oxaz | 1984 |
Rapid decline in penicillinase-producing Neisseria gonorrhoeae in Hong Kong associated with emerging 4-fluoroquinolone resistance.
Topics: Drug Resistance, Microbial; Female; Gonorrhea; Hong Kong; Humans; Male; Microbial Sensitivity Tests; | 1995 |
Persistence of Neisseria gonorrhoeae strains with decreased susceptibilities to ciprofloxacin and ofloxacin in Cleveland, Ohio, from 1992 through 1993.
Topics: beta-Lactamases; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbial Sensi | 1994 |
Emerging in vitro resistance to quinolones in penicillinase-producing Neisseria gonorrhoeae strains in Hawaii.
Topics: Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Hawaii; Humans; Microbial Sensitivity Tests; N | 1994 |
[The combined therapy of patients with gonorrheal-chlamydial urogenital infections by leukinferon immunocorrection].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Chlamydia Infections; Cytokines; Doxycycline; Drug Combin | 1993 |
Decreased susceptibility of Neisseria gonorrhoeae to fluoroquinolones--Ohio and Hawaii, 1992-1994.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Hawaii; Humans; Male; M | 1994 |
From the Centers for Disease Control and Prevention. Decreased susceptibility of Neisseria gonorrhoeae to fluoroquinolones--Ohio and Hawaii, 1992-1994.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Hawaii; Humans; Male; M | 1994 |
High prevalence of Neisseria gonorrhoeae strains with reduced susceptibility to fluoroquinolones in Japan.
Topics: Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbi | 1994 |
Ofloxacin susceptibilities of 5,667 Neisseria gonorrhoeae strains isolated in Hong Kong.
Topics: Gonorrhea; Hong Kong; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin | 1993 |
Effectiveness of norfloxacin and ofloxacin for treatment of gonorrhoea and decrease of in vitro susceptibility to quinolones over time in Rwanda.
Topics: Administration, Oral; Adult; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Neisseria gonorrho | 1993 |
[Treatment of uncomplicated gonorrhea in adults. New guidelines from the working group against gonorrhea].
Topics: Administration, Oral; Adult; Anti-Infective Agents; Ciprofloxacin; Female; Gonorrhea; Humans; Male; | 1996 |
Detection of quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluo | 1996 |
Fluoroquinolone treatment failure in gonorrhea. Emergence of a Neisseria gonorrhoeae strain with enhanced resistance to fluoroquinolones.
Topics: Adult; Anti-Infective Agents; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Gonorrhea; Hu | 1997 |
Neisseria gonorrhoeae resistant to ciprofloxacin and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Gonorrhea; Humans; Neisseria gonor | 1998 |
Genotypic evolution in a quinolone-resistant Neisseria gonorrhoeae isolate from a patient with clinical failure of levofloxacin treatment.
Topics: Adult; Anti-Infective Agents; Chromosomes, Bacterial; DNA, Bacterial; Drug Resistance, Microbial; Ge | 1999 |
Correlation between in vitro quinolone susceptibility of Neisseria gonorrhoeae and outcome of treatment of gonococcal urethritis with single-dose ofloxacin.
Topics: Adult; Anti-Infective Agents; Cost-Benefit Analysis; Female; Gonorrhea; Humans; In Vitro Techniques; | 1999 |
National guideline for the management of gonorrhoea in adults. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Contact Tracing; Female; Gonorrhea; Humans; | 1999 |
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates.
Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluo | 2000 |
First isolate of a Neisseria gonorrhoeae strain associated with an ofloxacin treatment failure in Spain: case report.
Topics: Adult; Anti-Infective Agents; Drug Resistance, Bacterial; Gonorrhea; Humans; Male; Neisseria gonorrh | 2001 |
Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin.
Topics: Acute Disease; Adult; Chlamydia Infections; Emergency Medical Services; Female; Follow-Up Studies; G | 1992 |
[Bacteriological and clinical studies on levofloxacin in male gonococcal urethritis].
Topics: Administration, Oral; Adolescent; Adult; Chlamydia trachomatis; Drug Resistance, Microbial; Gonorrhe | 1992 |
Treatment of choice for gonorrhea in Connecticut.
Topics: Ceftriaxone; Connecticut; Cost Control; Gonorrhea; Humans; Medical Indigency; Ofloxacin; Quality Ass | 1992 |
[Clinical analysis of male urethritis].
Topics: Adolescent; Adult; Child; Gonorrhea; Humans; Japan; Lymphogranuloma Venereum; Male; Middle Aged; Min | 1991 |
[Treatment of gonococcal urethritis].
Topics: Adult; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Gonorrhea; Humans; Levofloxacin | 1991 |
[Clinical effect and laboratory observation of ofloxacin in the treatment of typhoid fever, bacillary dysentery and gonorrhea].
Topics: Adult; Dysentery, Bacillary; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Ag | 1991 |
The in vitro activity of norfloxacin, ofloxacin and ciprofloxacin and other antibiotics in current use against Neisseria gonorrhoeae.
Topics: Ampicillin; Ampicillin Resistance; Ciprofloxacin; Doxycycline; Drug Resistance, Microbial; Gonorrhea | 1989 |
Low dose oral ofloxacin to treat gonorrhoea in Hong Kong.
Topics: Administration, Oral; Gonorrhea; Hong Kong; Humans; Male; Ofloxacin | 1989 |
Ofloxacin in the treatment of gonococcal and chlamydial urethritis.
Topics: Adult; Chlamydia Infections; Chlamydia trachomatis; Female; Gonorrhea; Humans; Male; Ofloxacin; Piva | 1988 |
[Studies of clinical efficacy of ofloxacin against male urethritis caused by Chlamydia trachomatis].
Topics: Adult; Aged; Chlamydia Infections; Chlamydia trachomatis; Drug Evaluation; Gonorrhea; Humans; Male; | 1988 |
The efficacy of ofloxacin against infection caused by Neisseria gonorrhoeae and Chlamydia trachomatis.
Topics: Chlamydia Infections; Chlamydia trachomatis; Female; Follow-Up Studies; Gonorrhea; Male; Ofloxacin | 1988 |
[One-dose treatment of male gonococcal urethritis by ofloxacin].
Topics: Adult; Anti-Infective Agents; Gonorrhea; Humans; Male; Ofloxacin; Oxazines; Urethritis | 1987 |
[Treatment with ofloxacin (RU 43280) of uncomplicated bacterial urethritis in males].
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Gonorrhea; Humans; Male; | 1986 |