Page last updated: 2024-11-01

ofloxacin and Necrotizing Pyelonephritis

ofloxacin has been researched along with Necrotizing Pyelonephritis in 36 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to investigate the urinary bactericidal titers (UBTs) and 24-h area under the UBT-versus-time curve (AUBT) of intravenous doripenem (500 mg every 8 h [q8h]), a new carbapenem, versus those of intravenous levofloxacin (250 mg q24h) in patients with complicated urinary tract infections (cUTIs) or pyelonephritis."9.14Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis. ( Naber, KG; Redman, R; Wagenlehner, C; Wagenlehner, FM; Weidner, W, 2009)
"Doripenem was evaluated in adults with complicated urinary tract infections and pyelonephritis in two phase 3 studies."9.14Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis. ( Damiao, R; Davies, T; Kaniga, K; Kotey, P; Naber, KG; Redman, R, 2010)
"A clinical study was conducted to compare the efficacy and safety of levofloxacin 750 mg once daily for 5 days to ciprofloxacin twice daily for 10 days for the treatment of complicated urinary tract infections (cUTI) or acute pyelonephritis (AP)."9.13A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis. ( Fisher, AC; Kahn, JB; Kaul, S; Khashab, M; Peterson, J, 2008)
"A double-blind, noninferiority trial was conducted to establish the safety and efficacy of a once-daily, 5-day course of levofloxacin 750 mg compared to a twice-daily, 10-day course of ciprofloxacin in complicated urinary tract infections (cUTI) and acute pyelonephritis (AP)."9.12A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis. ( Brown, P; Fisher, AC; Kahn, JB; Kaul, S; Khashab, M; Klausner, HA; Peterson, J, 2007)
"To evaluate, in two randomized, multicenter trials, levofloxacin compared with ciprofloxacin and lomefloxacin for efficacy and safety in treating acute pyelonephritis."9.08Levofloxacin versus ciprofloxacin versus lomefloxacin in acute pyelonephritis. ( Callery-D'Amico, S; Fowler, CL; Kim, SS; Klimberg, IN; Richard, GA, 1998)
"The efficacy and safety of parenteral ofloxacin were evaluated in an open, multicenter study of hospitalized patients with pyelonephritis."9.07Multicenter open-label study of parenteral ofloxacin in treatment of pyelonephritis in adults. ( Cox, CE; Gentry, LO; Rodriguez-Gomez, G, 1992)
"The interim findings of two studies of intravenous ofloxacin for the treatment of pyelonephritis are presented."9.07Parenteral ofloxacin in treatment of pyelonephritis. ( Cox, CE, 1991)
"The objective of this study was to assess the in vitro activity of levofloxacin compared to other antibiotics against Escherichia coli strains isolated from female patients with acute pyelonephritis in 23 French hospitals in 2005."7.74[In vitro activity of levofloxacin against Escherichia coli strains in acute pyelonephritis, in France in 2005]. ( Dib-Smahi, C; Lascols, C; Soussy, CJ, 2007)
"This pilot study was undertaken to characterise the pharmacokinetics, pharmacodynamics and potential clinical efficacy of levofloxacin 750 mg once daily for 5 days for treatment of women with acute uncomplicated pyelonephritis."7.74Pharmacokinetics/pharmacodynamics of levofloxacin 750 mg once daily in young women with acute uncomplicated pyelonephritis. ( Bryski, L; Duckworth, H; Harding, G; Nicolle, L; Sitar, D; Zhanel, G, 2008)
" In a murine model of hematogenous pyelonephritis, the in vivo efficacies of levofloxacin and ciprofloxacin were evaluated against two methicillin-susceptible and two methicillin-resistant S."7.69In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains. ( Barrett, JF; Frosco, MB; Kulwich, BA; Licata, L; Melton, JL; Stewart, FP, 1996)
"Two quinolones, fleroxacin and ofloxacin were used as oral treatment in a model of experimental pyelonephritis in rats."7.67Comparative studies of fleroxacin and ofloxacin in experimental pyelonephritis. ( Ritzerfeld, W, 1988)
"Doripenem was found not to be inferior to levofloxacin in terms of therapeutics and is now approved for use in the United States and Europe for the treatment of adults with cUTI, including pyelonephritis."6.74Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis. ( Hedrich, D; Kaniga, K; Kotey, P; Llorens, L; Naber, KG; Redman, R, 2009)
"The aim of this study was to investigate the urinary bactericidal titers (UBTs) and 24-h area under the UBT-versus-time curve (AUBT) of intravenous doripenem (500 mg every 8 h [q8h]), a new carbapenem, versus those of intravenous levofloxacin (250 mg q24h) in patients with complicated urinary tract infections (cUTIs) or pyelonephritis."5.14Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis. ( Naber, KG; Redman, R; Wagenlehner, C; Wagenlehner, FM; Weidner, W, 2009)
"To evaluate the clinical and bacterial efficacies and the safety of antofloxacin hydrochloride tablets in the treatment of acute exacerbations of chronic bronchitis (AECB) and acute pyelonephritis (AP)."5.14A phase II study of antofloxacin hydrochloride, a novel fluoroquinolone, for the treatment of acute bacterial infections. ( Bai, C; Huang, W; Mei, C; Wang, J; Xiao, Y; Xiu, Q; Xu, N; Zheng, Q, 2010)
"Doripenem was evaluated in adults with complicated urinary tract infections and pyelonephritis in two phase 3 studies."5.14Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis. ( Damiao, R; Davies, T; Kaniga, K; Kotey, P; Naber, KG; Redman, R, 2010)
"A clinical study was conducted to compare the efficacy and safety of levofloxacin 750 mg once daily for 5 days to ciprofloxacin twice daily for 10 days for the treatment of complicated urinary tract infections (cUTI) or acute pyelonephritis (AP)."5.13A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis. ( Fisher, AC; Kahn, JB; Kaul, S; Khashab, M; Peterson, J, 2008)
"A double-blind, noninferiority trial was conducted to establish the safety and efficacy of a once-daily, 5-day course of levofloxacin 750 mg compared to a twice-daily, 10-day course of ciprofloxacin in complicated urinary tract infections (cUTI) and acute pyelonephritis (AP)."5.12A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis. ( Brown, P; Fisher, AC; Kahn, JB; Kaul, S; Khashab, M; Klausner, HA; Peterson, J, 2007)
" They were compared with 23 acute pyelonephritis patients given ciprofloxacin in a dose 1 g/day."5.09[Tavanik effectiveness and safety in the treatment of urinary tract infection complications]. ( Loran, OB; Pushkar', DIu; Rasner, PI, 2001)
"Fifteen patients with various forms of pyelonephritis and chronic cystitis were treated with ofloxacin."5.08[Comprehensive treatment with ofloxacin in pyo-inflammatory urologic diseases]. ( Pytel', IuA; Volkova, VS, 1996)
"To evaluate, in two randomized, multicenter trials, levofloxacin compared with ciprofloxacin and lomefloxacin for efficacy and safety in treating acute pyelonephritis."5.08Levofloxacin versus ciprofloxacin versus lomefloxacin in acute pyelonephritis. ( Callery-D'Amico, S; Fowler, CL; Kim, SS; Klimberg, IN; Richard, GA, 1998)
"The efficacy and safety of parenteral ofloxacin were evaluated in an open, multicenter study of hospitalized patients with pyelonephritis."5.07Multicenter open-label study of parenteral ofloxacin in treatment of pyelonephritis in adults. ( Cox, CE; Gentry, LO; Rodriguez-Gomez, G, 1992)
"The interim findings of two studies of intravenous ofloxacin for the treatment of pyelonephritis are presented."5.07Parenteral ofloxacin in treatment of pyelonephritis. ( Cox, CE, 1991)
"The objective of this study was to assess the in vitro activity of levofloxacin compared to other antibiotics against Escherichia coli strains isolated from female patients with acute pyelonephritis in 23 French hospitals in 2005."3.74[In vitro activity of levofloxacin against Escherichia coli strains in acute pyelonephritis, in France in 2005]. ( Dib-Smahi, C; Lascols, C; Soussy, CJ, 2007)
"This pilot study was undertaken to characterise the pharmacokinetics, pharmacodynamics and potential clinical efficacy of levofloxacin 750 mg once daily for 5 days for treatment of women with acute uncomplicated pyelonephritis."3.74Pharmacokinetics/pharmacodynamics of levofloxacin 750 mg once daily in young women with acute uncomplicated pyelonephritis. ( Bryski, L; Duckworth, H; Harding, G; Nicolle, L; Sitar, D; Zhanel, G, 2008)
" In a murine model of hematogenous pyelonephritis, the in vivo efficacies of levofloxacin and ciprofloxacin were evaluated against two methicillin-susceptible and two methicillin-resistant S."3.69In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains. ( Barrett, JF; Frosco, MB; Kulwich, BA; Licata, L; Melton, JL; Stewart, FP, 1996)
"Two quinolones, fleroxacin and ofloxacin were used as oral treatment in a model of experimental pyelonephritis in rats."3.67Comparative studies of fleroxacin and ofloxacin in experimental pyelonephritis. ( Ritzerfeld, W, 1988)
"Ofloxacin, a new fluoroquinolone, was given to fifty patients (29 females and 21 males) aged 25 to 86 years with urinary tract infection or prostatitis."3.67[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections]. ( Acar, JF; Guibert, J, 1986)
"The therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 was compared in alloxan-induced diabetic mice with experimental respiratory and urinary tract infections."3.67Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice. ( Nishino, T; Obana, Y, 1988)
"The antibacterial activity of ofloxacin, a new gyrase inhibitor, was tested in experimental acute occlusive pyelonephritis in rats caused by Escherichia coli O4:H5 and Pseudomonas aeruginosa A 9532."3.67[Results of ofloxacin treatment of experimental urinary tract infections]. ( Ritzerfeld, W, 1986)
"Doripenem was found not to be inferior to levofloxacin in terms of therapeutics and is now approved for use in the United States and Europe for the treatment of adults with cUTI, including pyelonephritis."2.74Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis. ( Hedrich, D; Kaniga, K; Kotey, P; Llorens, L; Naber, KG; Redman, R, 2009)
"Ofloxacin was used in the empirical and etiotropic therapy of patients with severe urinary tract infection."2.68[Outlook and experience in using ofloxacin in urology]. ( Derevianko, II; Kotliarova, GA; Siniukhin, VN, 1996)
"Bacteremia was associated in 44% of uncomplicated and 8% of APN at risk of complications."1.40Antibiotic resistance in adult female patients hospitalized for acute pyelonephritis: rates and predicting factors. ( Caron, F; Choplin-Renard, J; Etienne, M; Pestel-Caron, M; Van Elslande, H, 2014)
"Pyelonephritis is rarely considered in the differential diagnosis of acute kidney injury."1.37Acute kidney injury from pyelonephritis in an elderly man: case report. ( Alroumoh, M; El-Kass, G; Galler, M; Husain, S; Mohan, P; Seshan, SV, 2011)
"We present the case of a patient with ADPKD and suspected cyst infection caused by group B streptococcus who was treated successfully with levofloxacin and ampicillin."1.33Levofloxacin penetration into a renal cyst in a patient with autosomal dominant polycystic kidney disease. ( Hiyama, L; Miller, LG; Tang, A, 2006)
"Treatment with ofloxacin in 15 patients with chronic renal failure at different stages is reported with respect to patients undergoing hemodialysis treatment."1.27[Ofloxacin treatment in nephrologic problem patients with various degrees of chronic renal failure (including dialysis treatment). Preliminary results]. ( Dörfler, A; Schulz, W, 1986)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19906 (16.67)18.7374
1990's7 (19.44)18.2507
2000's16 (44.44)29.6817
2010's7 (19.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Etienne, M1
Van Elslande, H1
Choplin-Renard, J1
Pestel-Caron, M1
Caron, F1
Bedoin, M1
Cazorla, C1
Lucht, F1
Berthelot, P1
Boyer, M1
Carricajo, A1
Guérin, T1
Viallon, A1
Talan, DA1
Krishnadasan, A1
Abrahamian, FM1
Stamm, WE1
Moran, GJ1
Wagenlehner, FM1
Wagenlehner, C1
Redman, R3
Weidner, W1
Naber, KG3
Davila, G1
Ruiz-Hornillos, J1
Rojas, P1
De Castro, F1
Zubeldia, JM1
Llorens, L1
Kaniga, K2
Kotey, P2
Hedrich, D1
Mirone, V1
Wang, J1
Xiao, Y1
Huang, W1
Xu, N1
Bai, C1
Xiu, Q1
Mei, C1
Zheng, Q1
Rafat, C1
Vimont, S1
Ancel, PY1
Xu-Dubois, YC1
Mesnard, L1
Ouali, N1
Denis, M1
Vandewalle, A1
Rondeau, E1
Hertig, A1
Damiao, R1
Davies, T1
Tsuruoka, S1
Yokota, N1
Hayasaka, T1
Saito, T1
Yamagata, K1
Husain, S1
Alroumoh, M1
Mohan, P1
El-Kass, G1
Seshan, SV1
Galler, M1
Tash, K1
Serra, AL1
Klein, M1
Nitsch, D1
Dürr, D1
Wermuth, B1
Frey, FJ1
Hiyama, L1
Tang, A1
Miller, LG1
Klausner, HA1
Brown, P1
Peterson, J3
Kaul, S3
Khashab, M3
Fisher, AC2
Kahn, JB3
Soussy, CJ1
Lascols, C1
Dib-Smahi, C1
Fisher, A1
Nicolle, L1
Duckworth, H1
Sitar, D1
Bryski, L1
Harding, G1
Zhanel, G1
Klesel, N1
Geweniger, KH1
Koletzki, P1
Isert, D1
Limbert, M1
Markus, A1
Riess, G1
Schramm, H1
Iyer, P1
Frosco, MB1
Melton, JL1
Stewart, FP1
Kulwich, BA1
Licata, L1
Barrett, JF1
Pytel', IuA1
Volkova, VS1
Derevianko, II1
Kotliarova, GA1
Siniukhin, VN1
Richard, GA1
Klimberg, IN1
Fowler, CL1
Callery-D'Amico, S1
Kim, SS1
Fujita, K1
Mizuno, T1
Ushiyama, T1
Suzuki, K1
Hadano, S1
Satoh, S1
Kambayashi, T1
Mugiya, S1
Nakano, M1
Revelo, MP1
Paueksakon, P1
Goral, S1
Helderman, H1
Fogo, AB1
Loran, OB1
Pushkar', DIu1
Rasner, PI1
Cox, CE2
Gentry, LO1
Rodriguez-Gomez, G1
Ritzerfeld, W2
Obana, Y1
Nishino, T1
Schulz, W1
Dörfler, A1
Guerra, L1
Erani, E1
Xerri, L1
Guibert, J1
Acar, JF1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-Blind, Randomized, Phase 3 Study of Doripenem Verus a Comparator Antibiotic in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis[NCT00229021]Phase 3741 participants (Actual)Interventional2003-12-31Completed
A Multicenter, Phase 3 Study of the Safety and Effectiveness of Doripenem in Complicated Lower Urinary Tract Infection or Pyelonephritis[NCT00210990]Phase 3403 participants (Actual)Interventional2004-03-31Completed
A Multicenter, Double-blind, Randomized Study to Compare the Efficacy and Safety of Levofloxacin 750 mg Once Daily for Five Days Versus Ciprofloxacin Twice Daily for Ten Days in the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis[NCT00210886]Phase 31,109 participants (Actual)Interventional2004-10-31Completed
Controlling Antimicrobial Use Through Reducing Unnecessary Treatment of Catheter Associated Urinary Tract Infections (CARCUTI)[NCT02650518]Phase 2/Phase 3500 participants (Anticipated)Interventional2015-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ofloxacin and Necrotizing Pyelonephritis

ArticleYear
[From cystitis to bacterial prostatitis: experience with levofloxacin].
    Le infezioni in medicina, 2009, Volume: 17 Suppl 5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cystitis; Double-Blind Method; Drug Therapy, Combinatio

2009

Trials

14 trials available for ofloxacin and Necrotizing Pyelonephritis

ArticleYear
Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Carbapenems; Doripenem; Double-Blin

2009
Intravenous doripenem at 500 milligrams versus levofloxacin at 250 milligrams, with an option to switch to oral therapy, for treatment of complicated lower urinary tract infection and pyelonephritis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Carbapenems; Doripenem; Double-Blind Method; Fema

2009
A phase II study of antofloxacin hydrochloride, a novel fluoroquinolone, for the treatment of acute bacterial infections.
    Chemotherapy, 2010, Volume: 56, Issue:5

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bronchitis, Chronic; Demography; Double-Blind Met

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
Safety and efficacy of intravenous doripenem for the treatment of complicated urinary tract infections and pyelonephritis.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6

    Topics: Aged; Anti-Infective Agents, Urinary; Carbapenems; Doripenem; Double-Blind Method; Female; Genotype;

2010
A trial of levofloxacin 750 mg once daily for 5 days versus ciprofloxacin 400 mg and/or 500 mg twice daily for 10 days in the treatment of acute pyelonephritis.
    Current medical research and opinion, 2007, Volume: 23, Issue:11

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Ciprofloxacin; Double-Blind Method; Drug Administ

2007
Identification and pretherapy susceptibility of pathogens in patients with complicated urinary tract infection or acute pyelonephritis enrolled in a clinical study in the United States from November 2004 through April 2006.
    Clinical therapeutics, 2007, Volume: 29, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Ciprof

2007
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis.
    Urology, 2008, Volume: 71, Issue:1

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Do

2008
[Comprehensive treatment with ofloxacin in pyo-inflammatory urologic diseases].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:9

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Infective Agents, Urinary; Anti-Inflammatory

1996
[Outlook and experience in using ofloxacin in urology].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1996, Volume: 41, Issue:9

    Topics: Administration, Oral; Anti-Infective Agents, Urinary; Drug Administration Schedule; Forecasting; Gra

1996
Levofloxacin versus ciprofloxacin versus lomefloxacin in acute pyelonephritis.
    Urology, 1998, Volume: 52, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Fem

1998
Complicating risk factors for pyelonephritis after extracorporeal shock wave lithotripsy.
    International journal of urology : official journal of the Japanese Urological Association, 2000, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Humans; Kidn

2000
[Tavanik effectiveness and safety in the treatment of urinary tract infection complications].
    Klinicheskaia meditsina, 2001, Volume: 79, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Male; Middle Aged; Of

2001
Multicenter open-label study of parenteral ofloxacin in treatment of pyelonephritis in adults.
    Urology, 1992, Volume: 39, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Drug Administration Schedule; Female; Humans;

1992
Parenteral ofloxacin in treatment of pyelonephritis.
    Urology, 1991, Volume: 37, Issue:3 Suppl

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Ceftazidime; Female; Humans; Infusions, Parent

1991

Other Studies

21 other studies available for ofloxacin and Necrotizing Pyelonephritis

ArticleYear
Antibiotic resistance in adult female patients hospitalized for acute pyelonephritis: rates and predicting factors.
    Medecine et maladies infectieuses, 2014, Volume: 44, Issue:5

    Topics: Acute Disease; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Catchment Area, Heal

2014
Risk factors for quinolone-resistance in women presenting with Escherichia coli acute pyelonephritis.
    Medecine et maladies infectieuses, 2014, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Catchment Area, Health; Cohort St

2014
Prevalence and risk factor analysis of trimethoprim-sulfamethoxazole- and fluoroquinolone-resistant Escherichia coli infection among emergency department patients with pyelonephritis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Nov-01, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ciprofloxacin; Cross-Sectional Studies; Drug Resistance,

2008
Toxic epidermal necrolysis induced by levofloxacin.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:5

    Topics: Fatal Outcome; Female; Humans; Levofloxacin; Middle Aged; Ofloxacin; Pyelonephritis; Stevens-Johnson

2009
Ofloxacin: new applications for the prevention of urinary tract infections in renal graft recipients.
    Transplant infectious disease : an official journal of the Transplantation Society, 2011, Volume: 13, Issue:4

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Dru

2011
Pharmacokinetics of multiple-dose levofloxacin in hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011, Volume: 58, Issue:3

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Half-Life; Humans; Levofloxacin; Middle Aged; Ofl

2011
Acute kidney injury from pyelonephritis in an elderly man: case report.
    International urology and nephrology, 2011, Volume: 43, Issue:3

    Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Diagnosis, Differential;

2011
Rahnella aquatilis bacteremia from a suspected urinary source.
    Journal of clinical microbiology, 2005, Volume: 43, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Lev

2005
A puzzling case of high serum creatinine in a healthy woman.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Creatinine; Drug Administration Schedule; False Positive Reactions; Fe

2006
Levofloxacin penetration into a renal cyst in a patient with autosomal dominant polycystic kidney disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Biological Availability; Drug Therapy, Combination; Female

2006
[In vitro activity of levofloxacin against Escherichia coli strains in acute pyelonephritis, in France in 2005].
    Medecine et maladies infectieuses, 2007, Volume: 37, Issue:11

    Topics: Acute Disease; Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; France; Humans;

2007
Pharmacokinetics/pharmacodynamics of levofloxacin 750 mg once daily in young women with acute uncomplicated pyelonephritis.
    International journal of antimicrobial agents, 2008, Volume: 31, Issue:3

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Area Under Curve; Escherichia coli Infections; F

2008
Chemotherapeutic activity of levofloxacin (HR 355, DR-3355) against systemic and localized infections in laboratory animals.
    The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:6

    Topics: Abscess; Animals; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Female; Granuloma; Kle

1995
In vivo efficacies of levofloxacin and ciprofloxacin in acute murine hematogenous pyelonephritis induced by methicillin-susceptible and-resistant Staphylococcus aureus strains.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:11

    Topics: Acute Disease; Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Female; Kidne

1996
A 14-year-old boy with kidney allograft failure in the first month after transplantation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:4

    Topics: Acute Disease; Adolescent; Anti-Infective Agents, Urinary; Biopsy; Creatinine; Diagnosis, Differenti

2000
Comparative studies of fleroxacin and ofloxacin in experimental pyelonephritis.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22 Suppl D

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Escherichia coli; Fleroxacin; Half-Life; Klebsiella;

1988
Therapeutic efficacy of ofloxacin, ciprofloxacin and NY-198 in experimentally infected normal and alloxan-induced diabetic mice.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:5

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Experimental; Female; Fluoroquinol

1988
[Ofloxacin treatment in nephrologic problem patients with various degrees of chronic renal failure (including dialysis treatment). Preliminary results].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Adult; Aged; Aluminum Hydroxide; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infections; Cre

1986
Ofloxacin: therapeutic activity in experimental infections.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:6

    Topics: Administration, Oral; Agranulocytosis; Animals; Anti-Infective Agents; Female; Male; Mice; Ofloxacin

1986
[Results of ofloxacin treatment of experimental urinary tract infections].
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Animals; Anti-Infective Agents, Urinary; Dose-Response Relationship, Drug; Escherichia coli Infectio

1986
[Ofloxacin (RU 43280): clinical evaluation in urinary and prostatic infections].
    Pathologie-biologie, 1986, Volume: 34, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cystitis; Female; Humans; Male; Middle Age

1986