ofloxacin has been researched along with Nausea in 13 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide." | 9.12 | Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007) |
| " This study concluded that the dosage regimen of LVFX 500 mg once daily was effective and tolerable for the treatment of LRTIs and UTIs." | 6.74 | Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China. ( Chen, BY; Ding, GH; Duan, J; Gu, JM; Guo, DY; Hao, QL; Huang, HH; Huang, JA; Li, HY; Li, QH; Liu, A; Lü, XJ; Ma, H; Ren, ZY; Shen, HH; Shi, MH; Si, B; Sun, SH; Sun, TY; Wu, GM; Xia, QM; Xiao, W; Xiao, ZK; Xiu, QY; Yang, HF; Yang, HP; Yao, WZ; Ying, KJ; Yu, YS; Yue, HM; Zhang, W; Zhang, YY; Zheng, HG, 2009) |
| "The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide." | 5.12 | Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007) |
| " Nausea, vomiting, and diarrhoea were the most frequently reported adverse events." | 2.74 | Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia. ( Calistru, PI; Castaing, N; Chernyak, V; Cooper, CA; Dartois, N; Gandjini, H; Milutinovic, S; Strausz, J; Tanaseanu, C; Zolubas, M, 2009) |
| " This study concluded that the dosage regimen of LVFX 500 mg once daily was effective and tolerable for the treatment of LRTIs and UTIs." | 2.74 | Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China. ( Chen, BY; Ding, GH; Duan, J; Gu, JM; Guo, DY; Hao, QL; Huang, HH; Huang, JA; Li, HY; Li, QH; Liu, A; Lü, XJ; Ma, H; Ren, ZY; Shen, HH; Shi, MH; Si, B; Sun, SH; Sun, TY; Wu, GM; Xia, QM; Xiao, W; Xiao, ZK; Xiu, QY; Yang, HF; Yang, HP; Yao, WZ; Ying, KJ; Yu, YS; Yue, HM; Zhang, W; Zhang, YY; Zheng, HG, 2009) |
| "Clarithromycin resistance was indirectly assessed by the (13)C-urea breath test, with a post-treatment value cut-off point at 15." | 2.73 | Levofloxacin-containing triple therapy to eradicate the persistent H. pylori after a failed conventional triple therapy. ( Chang, WL; Chen, WY; Cheng, HC; Sheu, BS; Wu, JJ; Yang, HB, 2007) |
| " The study indicates that ofloxacin is a safe and effective agent in the treatment of various infections." | 1.27 | Clinical safety and efficacy of ofloxacin. ( Concia, E; Grossi, P; Malfitano, A; Marone, P; Perversi, L, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 10 (76.92) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanders, JW | 1 |
| Frenck, RW | 1 |
| Putnam, SD | 1 |
| Riddle, MS | 1 |
| Johnston, JR | 1 |
| Ulukan, S | 1 |
| Rockabrand, DM | 1 |
| Monteville, MR | 1 |
| Tribble, DR | 1 |
| Sokolova, GB | 1 |
| Kirtaeva, OV | 1 |
| Lazareva, IaV | 1 |
| Tsybanev, AA | 1 |
| Tanaseanu, C | 1 |
| Milutinovic, S | 1 |
| Calistru, PI | 1 |
| Strausz, J | 1 |
| Zolubas, M | 1 |
| Chernyak, V | 1 |
| Dartois, N | 1 |
| Castaing, N | 1 |
| Gandjini, H | 1 |
| Cooper, CA | 1 |
| Zhang, YY | 1 |
| Huang, HH | 1 |
| Ren, ZY | 1 |
| Zheng, HG | 1 |
| Yu, YS | 1 |
| Lü, XJ | 1 |
| Xiao, ZK | 1 |
| Yang, HF | 1 |
| Xiu, QY | 1 |
| Chen, BY | 1 |
| Yue, HM | 1 |
| Hao, QL | 1 |
| Huang, JA | 1 |
| Ma, H | 1 |
| Xiao, W | 1 |
| Guo, DY | 1 |
| Si, B | 1 |
| Sun, SH | 1 |
| Zhang, W | 1 |
| Li, QH | 1 |
| Shen, HH | 1 |
| Duan, J | 1 |
| Li, HY | 1 |
| Yao, WZ | 1 |
| Gu, JM | 1 |
| Xia, QM | 1 |
| Ying, KJ | 1 |
| Liu, A | 1 |
| Yang, HP | 1 |
| Shi, MH | 1 |
| Sun, TY | 1 |
| Ding, GH | 1 |
| Wu, GM | 1 |
| Karabay, O | 1 |
| Sencan, I | 1 |
| Kayas, D | 1 |
| Sahin, I | 1 |
| Biswas, SK | 1 |
| Martinez, FJ | 1 |
| Grossman, RF | 1 |
| Zadeikis, N | 1 |
| Fisher, AC | 1 |
| Walker, K | 1 |
| Ambruzs, ME | 1 |
| Tennenberg, AM | 1 |
| Cheng, HC | 1 |
| Chang, WL | 1 |
| Chen, WY | 1 |
| Yang, HB | 1 |
| Wu, JJ | 1 |
| Sheu, BS | 1 |
| Hadiarto, M | 1 |
| Tjandra, YA | 1 |
| Hudoyo, A | 1 |
| Storr, M | 1 |
| Weigert, N | 1 |
| Fellbaum, C | 1 |
| Classen, M | 1 |
| Flannery, MT | 1 |
| Le, M | 1 |
| Altus, P | 1 |
| Stahlmann, R | 1 |
| Marone, P | 1 |
| Concia, E | 1 |
| Grossi, P | 1 |
| Malfitano, A | 1 |
| Perversi, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 3, Multicenter, Randomized, Double-Blind, Comparative Study Of The Efficacy And Safety Of Intravenous Tigecycline Vs Intravenous Levofloxacin To Treat Subjects Hospitalized With Community-Acquired Pneumonia[NCT00081575] | Phase 3 | 434 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for ofloxacin and Nausea
| Article | Year |
|---|---|
Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.
Topics: Adult; Azithromycin; Campylobacter Infections; Diarrhea; Double-Blind Method; Drug Therapy, Combinat | 2007 |
[Floracide, a Russian 3rd generation fluoroquinolone in complex therapy of tuberculosis].
Topics: Adult; Antitubercular Agents; Arthralgia; Diarrhea; Drug Resistance, Multiple, Bacterial; Drug Thera | 2008 |
Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Diarrhea; Dose-Respon | 2009 |
Clinical evaluation of oral levofloxacin 500 mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China.
Topics: Administration, Oral; Adolescent; Aged; Anti-Bacterial Agents; China; Dizziness; Drug Administration | 2009 |
Ofloxacin plus rifampicin versus doxycycline plus rifampicin in the treatment of brucellosis: a randomized clinical trial [ISRCTN11871179].
Topics: Adolescent; Adult; Brucellosis; Diarrhea; Doxycycline; Drug Costs; Drug Therapy, Combination; Female | 2004 |
Patient stratification in the management of acute bacterial exacerbation of chronic bronchitis: the role of levofloxacin 750 mg.
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amoxicillin-Potassium Clavul | 2005 |
Levofloxacin-containing triple therapy to eradicate the persistent H. pylori after a failed conventional triple therapy.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; | 2007 |
Treatment of multidrug-resistant tuberculosis in Indonesia.
Topics: Adult; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Indonesia; Isoniazid; M | 1996 |
5 other studies available for ofloxacin and Nausea
| Article | Year |
|---|---|
Chemotherapy of leprosy.
Topics: Anti-Bacterial Agents; Clofazimine; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Dr | 2004 |
[Polyposis of the gastrointestinal tract as a manifestation of diffuse follicular lymphatic hyperplasia].
Topics: Abdominal Pain; Adult; Anti-Infective Agents; Diagnosis, Differential; Diarrhea; Endoscopy, Gastroin | 1998 |
Endocarditis due to Salmonella.
Topics: Aged; Anti-Infective Agents; Cardiac Catheterization; Ceftriaxone; Cephalosporins; Combined Modality | 2001 |
Clinical toxicological aspects of fluoroquinolones.
Topics: Anti-Infective Agents; Bacterial Infections; Cardiovascular Diseases; Central Nervous System Disease | 2002 |
Clinical safety and efficacy of ofloxacin.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Drug Evaluation; Female; Humans; Male; Middle | 1988 |