ofloxacin has been researched along with Nasal Catarrh in 12 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective is to determine the effect of application of topical ofloxacin on nasal and sinus mucosa in patients with proven existence of bacterial biofilms and persistent chronic sinusitis after FESS." | 7.81 | Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis. ( Ezzat, WF; Fawaz, SA; Hamdy, TA; Rabie, H; Shokry, YA, 2015) |
| "A previous study found that a single 2-g dose of azithromycin extended release (AZ-ER) was as efficacious as 10 days of levofloxacin (LFX) 500 mg QD in adults with acute bacterial rhinosinusitis (ABRS)." | 7.74 | Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial. ( de Caprariis, PJ; Marple, BF; Reisman, A; Roberts, CS, 2007) |
| " The objective is to determine the effect of application of topical ofloxacin on nasal and sinus mucosa in patients with proven existence of bacterial biofilms and persistent chronic sinusitis after FESS." | 3.81 | Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis. ( Ezzat, WF; Fawaz, SA; Hamdy, TA; Rabie, H; Shokry, YA, 2015) |
| "A previous study found that a single 2-g dose of azithromycin extended release (AZ-ER) was as efficacious as 10 days of levofloxacin (LFX) 500 mg QD in adults with acute bacterial rhinosinusitis (ABRS)." | 3.74 | Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial. ( de Caprariis, PJ; Marple, BF; Reisman, A; Roberts, CS, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ezzat, WF | 1 |
| Fawaz, SA | 1 |
| Rabie, H | 1 |
| Hamdy, TA | 1 |
| Shokry, YA | 1 |
| El-Hennawi, DM | 1 |
| Ahmed, MR | 2 |
| Farid, AM | 1 |
| Al Murtadah, AM | 1 |
| Bakshi, SS | 2 |
| Videler, WJ | 1 |
| van Drunen, CM | 1 |
| Reitsma, JB | 1 |
| Fokkens, WJ | 1 |
| Guss, J | 1 |
| Abuzeid, WM | 1 |
| Doghramji, L | 1 |
| Edelstein, PH | 1 |
| Chiu, AG | 1 |
| Anon, JB | 1 |
| Marple, BF | 2 |
| Hadley, JA | 1 |
| Pea, F | 1 |
| Marioni, G | 1 |
| Pavan, F | 1 |
| Staffieri, C | 1 |
| Bottin, R | 1 |
| Staffieri, A | 1 |
| Furlanut, M | 1 |
| Roberts, CS | 1 |
| de Caprariis, PJ | 1 |
| Reisman, A | 1 |
1 review available for ofloxacin and Nasal Catarrh
| Article | Year |
|---|---|
Current management of acute bacterial rhinosinusitis and the role of moxifloxacin.
Topics: Anti-Bacterial Agents; Aza Compounds; Bacterial Infections; Clinical Trials as Topic; Drug Resistanc | 2005 |
2 trials available for ofloxacin and Nasal Catarrh
| Article | Year |
|---|---|
Comparative study of the efficacy of topical steroid and antibiotic combination therapy versus oral antibiotic alone when treating acute rhinosinusitis.
Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Amoxicillin; Anti-Bacterial Age | 2015 |
Nebulized bacitracin/colimycin: a treatment option in recalcitrant chronic rhinosinusitis with Staphylococcus aureus? A double-blind, randomized, placebo-controlled, cross-over pilot study.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacitracin; Chron | 2008 |
9 other studies available for ofloxacin and Nasal Catarrh
| Article | Year |
|---|---|
Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis.
Topics: Administration, Intranasal; Administration, Topical; Adult; Anti-Bacterial Agents; Biofilms; Case-Co | 2015 |
Comparative study of the efficacy of topical steroid and antibiotic combination therapy versus oral antibiotic alone when treating acute rhinosinusitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Dexamethasone; Female; Glucocorticoids; Humans; Male; Ofloxacin; | 2015 |
Comment on: Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis.
Topics: Biofilms; Chronic Disease; Humans; Nose; Ofloxacin; Paranasal Sinuses; Rhinitis; Sinusitis | 2016 |
Authors’ reply.
Topics: Amoxicillin; Anti-Bacterial Agents; Dexamethasone; Female; Glucocorticoids; Humans; Male; Ofloxacin; | 2015 |
Fluoroquinolone-resistant Pseudomonas aeruginosa in chronic rhinosinusitis.
Topics: Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Comorbidity; Drug Resistance, Bacterial; Fluo | 2009 |
Editorial commentary: dilemma in trial design: do current study designs adequately evaluate effectiveness antibiotic in ABRS?
Topics: Acute Disease; Azithromycin; Bacterial Infections; Chemistry, Pharmaceutical; Dose-Response Relation | 2005 |
Value of short-course antimicrobial therapy in acute bacterial rhinosinusitis.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Azithromycin; Bacterial Infections; Dose-Response Relat | 2005 |
Penetration of levofloxacin into paranasal sinuses mucosa of patients with chronic rhinosinusitis after a single 500 mg oral dose.
Topics: Adult; Aged; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chronic Disease; Female; H | 2007 |
Onset of symptom resolution in adults with acute bacterial rhinosinusitis treated with a single dose of azithromycin extended release compared with 10 days of levofloxacin: a retrospective analysis of a randomized, double-blind, double-dummy trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Dela | 2007 |