Page last updated: 2024-11-01

ofloxacin and Myelodysplastic Syndromes

ofloxacin has been researched along with Myelodysplastic Syndromes in 3 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmidt-Hieber, M1
Stroux, A1
Thiel, E1
Blau, IW1
Chou, SY1
Tsai, CC1
Kau, SC1
Kau, HC1
Hsu, WM1
Zaigraykin, N1
Kovalev, J1
Elias, N1
Naschitz, JE1

Trials

1 trial available for ofloxacin and Myelodysplastic Syndromes

ArticleYear
Antibacterial prophylaxis with levofloxacin in patients after allogeneic stem cell transplantation and neutrophil reconstitution: results from a double-blinded, placebo-controlled phase III trial and overview of recent clinical practice.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Double-Blind Method; Female; Humans; Leukemia, Myelo

2010

Other Studies

2 other studies available for ofloxacin and Myelodysplastic Syndromes

ArticleYear
Aeromonas hydrophila orbital cellulitis in a patient with myelodysplastic syndrome.
    Journal of the Chinese Medical Association : JCMA, 2004, Volume: 67, Issue:1

    Topics: Aeromonas hydrophila; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Cellulitis; Gr

2004
Levofloxacin-induced interstitial nephritis and vasculitis in an elderly woman.
    The Israel Medical Association journal : IMAJ, 2006, Volume: 8, Issue:10

    Topics: Acute Kidney Injury; Aged, 80 and over; Anti-Bacterial Agents; Fatal Outcome; Female; Humans; Levofl

2006