Page last updated: 2024-11-01

ofloxacin and Mycoplasma dispar Infection

ofloxacin has been researched along with Mycoplasma dispar Infection in 14 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"We report a case of lethal hepatitis possibly/probably associated with levofloxacin, doxy-cycline, and naproxen in a patient with acute M pneumoniae infection."7.75Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection. ( Andrade, RJ; Carrascosa, MF; Caviedes, JR; Lavín, AC; Lucena, MI; Mones, JC; Rivero, AP; Serrano, VB, 2009)
"To assess the safety and efficacy of a ten-day oral course of ofloxacin (400 mg 12 hourly) as compared with erythromycin (400 mg every 6 hours) for treatment of lower respiratory tract infections, fifty-two adult outpatients with pulmonary infiltrates (pneumonia) or with a cough and purulent sputum (bronchitis) were evaluated."5.07Treatment of lower respiratory infections in outpatients with ofloxacin compared with erythromycin. ( Hooton, TM; Lipsky, BA; Pecoraro, RE; Peugeot, RL, 1991)
"We report a case of lethal hepatitis possibly/probably associated with levofloxacin, doxy-cycline, and naproxen in a patient with acute M pneumoniae infection."3.75Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection. ( Andrade, RJ; Carrascosa, MF; Caviedes, JR; Lavín, AC; Lucena, MI; Mones, JC; Rivero, AP; Serrano, VB, 2009)
"Ofloxacin was administered orally in 32 cases (200 mg b."2.66[Treatment of pneumonia caused by Legionella, Mycoplasma, Chlamydiae and Rickettsia using ofloxacin]. ( Beuscart, C; Chidiac, C; Leroy, O; Mouton, Y; Senneville, E; Sivery, B; Vincent du Laurier, M, 1989)
"Sparfloxacin was more effective than levofloxacin and ofloxacin in both dosing regimens."1.29In vitro and in vivo activities of sparfloxacin against Mycoplasma pneumoniae. ( Irifune, K; Ishida, K; Kaku, M; Mizukane, R; Suyama, N; Takemura, H; Tanaka, H; Tomono, K; Usui, T; Yoshida, R, 1994)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's7 (50.00)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrascosa, MF1
Lucena, MI1
Andrade, RJ1
Caviedes, JR1
Lavín, AC1
Mones, JC1
Rivero, AP1
Serrano, VB1
Hawkins, S1
Rausch, CM1
McCanta, AC1
Ficko, C1
Mellon, G1
Andriamanantena, D1
Merens, A1
Rapp, C1
Fukushima, K1
Nakatsubo, M1
Noda, M1
Uenami, T1
Hayama, Y1
Tsuruta, N1
Oniki, S1
Saito, Y1
Niju, T1
Ikeda, T1
Duffy, LB1
Crabb, DM1
Bing, X1
Waites, KB1
Dunbar, LM1
Khashab, MM1
Kahn, JB1
Zadeikis, N1
Xiang, JX1
Tennenberg, AM1
Kaku, M2
Ishida, K2
Irifune, K1
Mizukane, R1
Takemura, H1
Yoshida, R1
Tanaka, H1
Usui, T2
Tomono, K1
Suyama, N1
Gohara, Y2
Arai, S2
Akashi, A2
Kuwano, K2
Tseng, CC1
Matsubara, S1
Matumoto, M1
Furudera, T1
Nishimoto, M1
Yano, T1
Oizumi, K1
Takeda, K1
Yamaguchi, T1
Kohno, S1
Koga, H1
Hara, K1
Chidiac, C2
Senneville, E2
Mouton, Y2
Peugeot, RL1
Lipsky, BA1
Hooton, TM1
Pecoraro, RE1
Kikuchi, N1
Kawashima, T1
Onozaki, I1
Leroy, O1
Beuscart, C1
Sivery, B1
Vincent du Laurier, M1

Reviews

1 review available for ofloxacin and Mycoplasma dispar Infection

ArticleYear
[Value of quinolones in the treatment of lower respiratory tract infections caused by intracellular organisms, excluding mycobacteria].
    Pathologie-biologie, 1992, Volume: 40, Issue:6

    Topics: Anti-Infective Agents; Chlamydia Infections; Ciprofloxacin; Enoxacin; Erythromycin; Humans; In Vitro

1992

Trials

4 trials available for ofloxacin and Mycoplasma dispar Infection

ArticleYear
Efficacy of 750-mg, 5-day levofloxacin in the treatment of community-acquired pneumonia caused by atypical pathogens.
    Current medical research and opinion, 2004, Volume: 20, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Chlamydophila pneumoniae; Community-Acquired Inf

2004
Experimental and clinical studies of sparfloxacin in Mycoplasma pneumoniae infection.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Lung; Male; Mesocricetus; Micr

1995
Treatment of lower respiratory infections in outpatients with ofloxacin compared with erythromycin.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:5

    Topics: Adult; Aged; Bronchitis; Chlamydia Infections; Erythromycin; Female; Humans; Legionnaires' Disease;

1991
[Treatment of pneumonia caused by Legionella, Mycoplasma, Chlamydiae and Rickettsia using ofloxacin].
    Pathologie-biologie, 1989, Volume: 37, Issue:10

    Topics: Adult; Aged; Female; France; Humans; Legionnaires' Disease; Male; Middle Aged; Multicenter Studies a

1989

Other Studies

9 other studies available for ofloxacin and Mycoplasma dispar Infection

ArticleYear
Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection.
    Clinical therapeutics, 2009, Volume: 31, Issue:5

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Ind

2009
Constrictive pericarditis secondary to infection with Mycoplasma pneumoniae.
    Current opinion in pediatrics, 2011, Volume: 23, Issue:1

    Topics: Adolescent; Anti-Bacterial Agents; Cardiac Tamponade; Diagnosis, Differential; Diuretics; Follow-Up

2011
[Acute Mycoplasma pneumonia pancreatitis].
    Medecine et maladies infectieuses, 2011, Volume: 41, Issue:11

    Topics: Abdominal Pain; Acute Disease; Anti-Bacterial Agents; Antibodies, Bacterial; China; DNA, Bacterial;

2011
Anaphylaxis due to intravenous levofloxacin with tolerance to garenoxacin.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:13

    Topics: Adult; Anaphylaxis; Anti-Bacterial Agents; Cross Reactions; Drug Hypersensitivity; Fluoroquinolones;

2012
Bactericidal activity of levofloxacin against Mycoplasma pneumoniae.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:3

    Topics: Anti-Bacterial Agents; Humans; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Mycoplasma pneum

2003
In vitro and in vivo activities of sparfloxacin against Mycoplasma pneumoniae.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4

    Topics: Animals; Anti-Infective Agents; Cricetinae; Fluoroquinolones; Humans; Levofloxacin; Lung; Mesocricet

1994
In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumoniae.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Drug Resistance, Mi

1993
Effects of new quinolones on Mycoplasma pneumoniae-infected hamsters.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Animals; Anti-Infective Agents; Antibodies, Bacterial; Ciprofloxacin; Cricetinae; Female; Fluoroquin

1993
[Clinical evaluations of ofloxacin in the treatment of Mycoplasma pneumoniae pneumonia in adults].
    The Japanese journal of antibiotics, 1990, Volume: 43, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Female; Humans; Male; Middle Aged; Ofloxacin; Pneumonia, My

1990