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ofloxacin and Mycobacterium Infections

ofloxacin has been researched along with Mycobacterium Infections in 19 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Mycobacterium Infections: Infections with bacteria of the genus MYCOBACTERIUM.

Research Excerpts

ExcerptRelevanceReference
"A systemic antibiotic, 1 g levofloxacin daily, had been started at the initial abscess operation."3.71[Osteomyelitis of the tibial head caused by Mycobacterium haemophilium in a patient with AIDS]. ( Brade, V; Enzensberger, R; Gruschke, A, 2002)
"Tubercular sternal osteomyelitis is a rare manifestation of tuberculosis."1.35Sternal tuberculosis. ( Howell, JM; Mohammadi, A, 2009)
"Multiple injections of ofloxacin (subcutaneous or oral) in combination with a Lactobacillus casei preparation, LC9018 (subcutaneous), in mice infected intravenously with Mycobacterium fortuitum led to a marked delay in the incidence of spinning disease, a lowered incidence of gross renal lesions, and an increase in the rate of elimination of organisms from the kidneys."1.28Effect of ofloxacin combined with Lactobacillus casei against Mycobacterium fortuitum infection induced in mice. ( Saito, H; Sato, K; Tomioka, H, 1990)
"A 58-year-old man with pulmonary disease due to Mycobacterium fortuitum was treated successfully with ofloxacin (0."1.27Ofloxacin and the treatment of pulmonary disease due to Mycobacterium fortuitum. ( Ichiyama, S; Tsukamura, M, 1987)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's6 (31.58)18.2507
2000's3 (15.79)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tam, PM1
Young, AL1
Cheng, L1
Congdon, N1
Lam, PT1
Disratthakit, A1
Doi, N1
Kelley, CF1
Armstrong, WS1
Eaton, ME1
Gruschke, A1
Enzensberger, R1
Brade, V1
Tam, WO1
Yew, WW4
Yam, WC1
Yuen, KY1
Wong, PC1
Tse, TF1
Mohammadi, A1
Howell, JM1
Padeĭskaia, EN1
Padełskaya, EN1
Tsukamura, M2
Yamori, S1
Wallace, RJ1
Bedsole, G1
Sumter, G1
Sanders, CV1
Steele, LC1
Brown, BA1
Smith, J1
Graham, DR1
Tomioka, H3
Sato, K3
Saito, H3
Kwan, SY3
Ma, WK3
Lui, KS1
Suen, HC1
Heap, BJ1
Aung-khin, M1
Mok, CK2
Khin, MA1
Watanabe, T1
Ichiyama, S1

Reviews

2 reviews available for ofloxacin and Mycobacterium Infections

ArticleYear
[Value of ciprofloxacin in the therapy of tuberculosis and other mycobacterioses].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1997, Volume: 42, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium

1997
[Ofloxacin in mycobacteriosis therapy].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1997, Volume: 42, Issue:11

    Topics: Animals; Anti-Infective Agents; Clinical Trials as Topic; Disease Models, Animal; Humans; Leprosy, T

1997

Other Studies

17 other studies available for ofloxacin and Mycobacterium Infections

ArticleYear
Tsukamurella: an unrecognized mimic of atypical mycobacterial keratitis? The first case report.
    Cornea, 2010, Volume: 29, Issue:3

    Topics: Actinomycetales; Actinomycetales Infections; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Cor

2010
In vitro activities of DC-159a, a novel fluoroquinolone, against Mycobacterium species.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Aminopyridines; Antitubercular Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Fluoroqu

2010
Disseminated Mycobacterium haemophilum infection.
    The Lancet. Infectious diseases, 2011, Volume: 11, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Anti-HIV Agents; Cellulitis; Clarithromyc

2011
[Osteomyelitis of the tibial head caused by Mycobacterium haemophilium in a patient with AIDS].
    Deutsche medizinische Wochenschrift (1946), 2002, Sep-20, Volume: 127, Issue:38

    Topics: Abscess; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Clarit

2002
Pacemaker infections due to rapidly growing mycobacteria: further experience.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2007, Volume: 11, Issue:1

    Topics: Acetamides; Aged; Anti-Infective Agents; Clarithromycin; Drug Therapy, Combination; Female; Humans;

2007
Sternal tuberculosis.
    The Journal of emergency medicine, 2009, Volume: 36, Issue:4

    Topics: Abscess; Adult; Anti-Bacterial Agents; Antitubercular Agents; Drug Therapy, Combination; Humans; Mal

2009
[Chemotherapeutic regimens for nontuberculous mycobacterial infection based on in-vitro susceptibility test results].
    Kekkaku : [Tuberculosis], 1990, Volume: 65, Issue:5

    Topics: Drug Resistance, Microbial; Drug Therapy, Combination; Enviomycin; Ethambutol; Humans; Isoniazid; My

1990
Activities of ciprofloxacin and ofloxacin against rapidly growing mycobacteria with demonstration of acquired resistance following single-drug therapy.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:1

    Topics: Adult; Aged; Ciprofloxacin; Drug Resistance, Microbial; Female; Humans; Male; Microbial Sensitivity

1990
Effect of ofloxacin combined with Lactobacillus casei against Mycobacterium fortuitum infection induced in mice.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Drug Synergism; Female; Injections, Subcutane

1990
Ofloxacin therapy of Mycobacterium fortuitum infection: further experience.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:5

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Mycobacterium Infections; Mycobacterium Infections,

1990
[Rifabutine in the treatment of mycobacterial infections resistant to rifampicin. Preliminary results. Group for the Study and Treatment of Resistant Mycobacterial Infections (GETIM)].
    Revue des maladies respiratoires, 1989, Volume: 6, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Drug Resistance, Microbial; Drug Therapy, Combinati

1989
Mycobacterium simiae as a cause of intra-abdominal disease: a case report.
    Tubercle, 1989, Volume: 70, Issue:3

    Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Myco

1989
Combination of ofloxacin and amikacin in the treatment of sternotomy wound infection.
    Chest, 1989, Volume: 95, Issue:5

    Topics: Adult; Aged; Amikacin; Cardiac Surgical Procedures; Drug Combinations; Female; Humans; Injections, I

1989
Single daily-dose ofloxacin monotherapy for Mycobacterium fortuitum sternotomy infection.
    Chest, 1989, Volume: 96, Issue:5

    Topics: Drug Administration Schedule; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycoba

1989
[In vitro and in vivo activities of norfloxacin, ofloxacin and ciprofloxacin against various mycobacteria].
    Kekkaku : [Tuberculosis], 1987, Volume: 62, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Mice; Mycobacteri

1987
Ofloxacin and the treatment of pulmonary disease due to Mycobacterium fortuitum.
    Chest, 1987, Volume: 92, Issue:6

    Topics: Humans; Lung Diseases; Male; Middle Aged; Mycobacterium Infections; Ofloxacin; Oxazines; Radiography

1987
[Environmental mycobacteria in Korea--II. Therapeutic effects of ofloxacin against infections due to isolates].
    Kekkaku : [Tuberculosis], 1987, Volume: 62, Issue:9

    Topics: Animals; Environmental Microbiology; Korea; Mice; Mice, Inbred Strains; Mycobacterium; Mycobacterium

1987