Page last updated: 2024-11-01

ofloxacin and Myasthenia Gravis

ofloxacin has been researched along with Myasthenia Gravis in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gunduz, A1
Turedi, S1
Kalkan, A1
Nuhoglu, I1
Azevedo, E1
Ribeiro, JA1
Polónia, J1
Pontes, C1

Other Studies

2 other studies available for ofloxacin and Myasthenia Gravis

ArticleYear
Levofloxacin induced myasthenia crisis.
    Emergency medicine journal : EMJ, 2006, Volume: 23, Issue:8

    Topics: Anti-Bacterial Agents; Humans; Levofloxacin; Male; Middle Aged; Myasthenia Gravis; Ofloxacin; Respir

2006
Probable exacerbation of myasthenia gravis by ofloxacin.
    Journal of neurology, 1993, Volume: 240, Issue:8

    Topics: Adult; Female; Humans; Myasthenia Gravis; Ofloxacin

1993