ofloxacin has been researched along with Meningitis in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Meningitis: Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The penetration of ofloxacin was studied in 22 patients with purulent meningitis or ventriculitis treated with conventional antibiotics." | 7.67 | Diffusion of ofloxacin into cerebrospinal fluid of patients with purulent meningitis or ventriculitis. ( Clair, B; Laisne, MJ; Pioget, JC; Regnier, B; Singlas, E; Vachon, F; Wolff, M, 1989) |
| "Ofloxacin diffusion into cerebrospinal fluid (CSF) was evaluated in nine patients with bacterial meningitis." | 7.67 | Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis. ( Bru, JP; Croize, J; Fourtillan, JB; Guyot, A; Leduc, D; Lefèbvre, MA; Micoud, M; Stahl, JP, 1986) |
| "After antibiotic prophylaxis with metronidazole and levofloxacin, a transrectal sextant biopsy was performed under the guide of transrectal ultrasonography (TRUS) for a 75-year-old suspicious patient with prostate adenocarcinoma." | 3.73 | Life-threatening meningitis resulting from transrectal prostate biopsy. ( Chen, SW; Shen, ZJ; Wang, H; Zhao, JP; Zhou, XL, 2005) |
| "The penetration of ofloxacin was studied in 22 patients with purulent meningitis or ventriculitis treated with conventional antibiotics." | 3.67 | Diffusion of ofloxacin into cerebrospinal fluid of patients with purulent meningitis or ventriculitis. ( Clair, B; Laisne, MJ; Pioget, JC; Regnier, B; Singlas, E; Vachon, F; Wolff, M, 1989) |
| "Ofloxacin diffusion into cerebrospinal fluid (CSF) was evaluated in nine patients with bacterial meningitis." | 3.67 | Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis. ( Bru, JP; Croize, J; Fourtillan, JB; Guyot, A; Leduc, D; Lefèbvre, MA; Micoud, M; Stahl, JP, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, ZJ | 1 |
| Chen, SW | 1 |
| Wang, H | 1 |
| Zhou, XL | 1 |
| Zhao, JP | 1 |
| Komachi, H | 1 |
| Uchihara, T | 1 |
| Saito, Y | 1 |
| Takewaki, S | 1 |
| Nagai, R | 1 |
| Furukawa, T | 1 |
| Staffensky, RH | 1 |
| Stolke, D | 1 |
| Malottke, R | 1 |
| Pioget, JC | 1 |
| Wolff, M | 1 |
| Singlas, E | 1 |
| Laisne, MJ | 1 |
| Clair, B | 1 |
| Regnier, B | 1 |
| Vachon, F | 1 |
| Stahl, JP | 1 |
| Croize, J | 1 |
| Lefèbvre, MA | 1 |
| Bru, JP | 1 |
| Guyot, A | 1 |
| Leduc, D | 1 |
| Fourtillan, JB | 1 |
| Micoud, M | 1 |
5 other studies available for ofloxacin and Meningitis
| Article | Year |
|---|---|
Life-threatening meningitis resulting from transrectal prostate biopsy.
Topics: Adenocarcinoma; Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Biopsy; Escherichia col | 2005 |
Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
Topics: Administration, Oral; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, An | 1996 |
[Cerebrospinal fluid penetration of ofloxacin (Tarivid) in non-inflamed meninges].
Topics: Adenoma; Administration, Oral; Adult; Bacterial Infections; Blood-Brain Barrier; Female; Humans; Mal | 1990 |
Diffusion of ofloxacin into cerebrospinal fluid of patients with purulent meningitis or ventriculitis.
Topics: Adolescent; Adult; Aged; Cerebral Ventricles; Diffusion; Encephalitis; Female; Half-Life; Humans; Ma | 1989 |
Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis.
Topics: Adult; Anti-Infective Agents; Bacterial Infections; Female; Humans; Male; Meningitis; Meningitis, Me | 1986 |